G Schlaug

Summary

Affiliation: Harvard University
Country: USA

Publications

  1. pmc Dual-hemisphere tDCS facilitates greater improvements for healthy subjects' non-dominant hand compared to uni-hemisphere stimulation
    Bradley W Vines
    Department of Neurology, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA 02215, USA
    BMC Neurosci 9:103. 2008
  2. pmc Perceiving pitch absolutely: comparing absolute and relative pitch possessors in a pitch memory task
    Katrin Schulze
    Department of Neurology, Music and Neuroimaging Laboratory, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA, 02215, USA
    BMC Neurosci 10:106. 2009
  3. pmc Effect of pre-stroke use of ACE inhibitors on ischemic stroke severity
    Magdy Selim
    Department of Neurology, Beth Israel Deaconess Medical Center, Boston, USA
    BMC Neurol 5:10. 2005
  4. ncbi request reprint Musicians differ from nonmusicians in brain activation despite performance matching
    Nadine Gaab
    Department of Neurology, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachusetts 02215, USA
    Ann N Y Acad Sci 999:385-8. 2003
  5. ncbi request reprint Effects of music training on the child's brain and cognitive development
    Gottfried Schlaug
    Department of Neurology, Music and Neuroimaging Laboratory, Beth Israel Deaconess Medical Center Harvard Medical School, 330 Brookline Avenue, Palmer 127, Boston, MA 02215, USA
    Ann N Y Acad Sci 1060:219-30. 2005
  6. pmc Transcranial direct current stimulation: a noninvasive tool to facilitate stroke recovery
    Gottfried Schlaug
    Department of Neurology, Neuroimaging and Stroke Recovery Laboratories, Beth Israel Deaconess Medical Center and Harvard Medical School, 330 Brookline Avenue, Boston, MA 02215, USA
    Expert Rev Med Devices 5:759-68. 2008
  7. pmc The use of non-invasive brain stimulation techniques to facilitate recovery from post-stroke aphasia
    Gottfried Schlaug
    Department of Neurology, Neuroimaging and Stroke Recovery Laboratories, Harvard Medical School and Beth Israel Deaconess Medical Center, 330 Brookline Avenue, Palmer 127, Boston, MA 02215, USA
    Neuropsychol Rev 21:288-301. 2011
  8. pmc Transcranial direct current stimulation in stroke recovery
    Gottfried Schlaug
    Neuroimaging and Stroke Recovery Laboratories, Department of Neurology, Beth Israel Deaconess Medical Center and Harvard Medical School, 330 Brookline Ave, Boston, MA 02215, USA
    Arch Neurol 65:1571-6. 2008
  9. pmc Training-induced neuroplasticity in young children
    Gottfried Schlaug
    Department of Neurology, Music and Neuroimaging Laboratory, Beth Israel Deaconess Medical Center, and Harvard Medical School, Boston, Massachusetts 02215, USA
    Ann N Y Acad Sci 1169:205-8. 2009
  10. pmc Evidence for plasticity in white-matter tracts of patients with chronic Broca's aphasia undergoing intense intonation-based speech therapy
    Gottfried Schlaug
    Music, Stroke Recovery, and Neuroimaging Laboratory, Department of Neurology, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachusetts 02215, USA
    Ann N Y Acad Sci 1169:385-94. 2009

Research Grants

Detail Information

Publications84

  1. pmc Dual-hemisphere tDCS facilitates greater improvements for healthy subjects' non-dominant hand compared to uni-hemisphere stimulation
    Bradley W Vines
    Department of Neurology, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA 02215, USA
    BMC Neurosci 9:103. 2008
    ..Participants performed a finger-sequencing task with the non-dominant hand before and after each stimulation. The dependent variable was the percentage of change in performance, comparing pre- and post-tDCS scores...
  2. pmc Perceiving pitch absolutely: comparing absolute and relative pitch possessors in a pitch memory task
    Katrin Schulze
    Department of Neurology, Music and Neuroimaging Laboratory, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA, 02215, USA
    BMC Neurosci 10:106. 2009
    ..The aim of this fMRI study was to examine the neural network underlying AP using a pitch memory experiment and contrasting two groups of musicians with each other, those that have AP and those that do not...
  3. pmc Effect of pre-stroke use of ACE inhibitors on ischemic stroke severity
    Magdy Selim
    Department of Neurology, Beth Israel Deaconess Medical Center, Boston, USA
    BMC Neurol 5:10. 2005
    ..We aimed to compare stroke severity between stroke patients who were taking ACEI before their stroke onset and those who were not, to examine the effects of pretreatment with ACEI on ischemic stroke severity...
  4. ncbi request reprint Musicians differ from nonmusicians in brain activation despite performance matching
    Nadine Gaab
    Department of Neurology, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachusetts 02215, USA
    Ann N Y Acad Sci 999:385-8. 2003
    ..Musicians showed greater right posterior temporal and supramarginal activation, whereas nonmusicians had greater activation of the left secondary auditory cortex...
  5. ncbi request reprint Effects of music training on the child's brain and cognitive development
    Gottfried Schlaug
    Department of Neurology, Music and Neuroimaging Laboratory, Beth Israel Deaconess Medical Center Harvard Medical School, 330 Brookline Avenue, Palmer 127, Boston, MA 02215, USA
    Ann N Y Acad Sci 1060:219-30. 2005
    ..Further, we present a comparison of the results in these children's studies with observations from our cross-sectional studies with adults...
  6. pmc Transcranial direct current stimulation: a noninvasive tool to facilitate stroke recovery
    Gottfried Schlaug
    Department of Neurology, Neuroimaging and Stroke Recovery Laboratories, Beth Israel Deaconess Medical Center and Harvard Medical School, 330 Brookline Avenue, Boston, MA 02215, USA
    Expert Rev Med Devices 5:759-68. 2008
    ..We will review tDCS's successful utilization in pilot and proof-of-principle stroke recovery studies, the different modes of tDCS currently in use, and the potential mechanisms underlying the neural effects of tDCS...
  7. pmc The use of non-invasive brain stimulation techniques to facilitate recovery from post-stroke aphasia
    Gottfried Schlaug
    Department of Neurology, Neuroimaging and Stroke Recovery Laboratories, Harvard Medical School and Beth Israel Deaconess Medical Center, 330 Brookline Avenue, Palmer 127, Boston, MA 02215, USA
    Neuropsychol Rev 21:288-301. 2011
    ..A better understanding of the predictors of recovery from natural outcome studies would also help to inform study design, and the selection of clinically meaningful outcome measures in future studies...
  8. pmc Transcranial direct current stimulation in stroke recovery
    Gottfried Schlaug
    Neuroimaging and Stroke Recovery Laboratories, Department of Neurology, Beth Israel Deaconess Medical Center and Harvard Medical School, 330 Brookline Ave, Boston, MA 02215, USA
    Arch Neurol 65:1571-6. 2008
    ..We review the role of TDCS as a facilitator of stroke recovery, the different modes of TDCS, and the potential mechanisms underlying the neural effects of TDCS...
  9. pmc Training-induced neuroplasticity in young children
    Gottfried Schlaug
    Department of Neurology, Music and Neuroimaging Laboratory, Beth Israel Deaconess Medical Center, and Harvard Medical School, Boston, Massachusetts 02215, USA
    Ann N Y Acad Sci 1169:205-8. 2009
    ..Our results show that it is intense musical experience/practice, not preexisting differences, that is responsible for the larger anterior CC area found in professional adult musicians...
  10. pmc Evidence for plasticity in white-matter tracts of patients with chronic Broca's aphasia undergoing intense intonation-based speech therapy
    Gottfried Schlaug
    Music, Stroke Recovery, and Neuroimaging Laboratory, Department of Neurology, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachusetts 02215, USA
    Ann N Y Acad Sci 1169:385-94. 2009
    ..This suggests that intense, long-term MIT leads to remodeling of the right AF and may provide an explanation for the sustained therapy effects that were seen in these six patients...
  11. pmc Impairment of speech production predicted by lesion load of the left arcuate fasciculus
    Sarah Marchina
    Department of Neurology, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA 02215, USA
    Stroke 42:2251-6. 2011
    ....
  12. pmc Bihemispheric brain stimulation facilitates motor recovery in chronic stroke patients
    R Lindenberg
    Department of Neurology, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA 02215, USA
    Neurology 75:2176-84. 2010
    ..In this sham-controlled randomized trial, we investigated whether noninvasive modulation of regional excitability of bilateral motor cortices in combination with physical and occupational therapy improves motor outcome after stroke...
  13. pmc Structural integrity of corticospinal motor fibers predicts motor impairment in chronic stroke
    R Lindenberg
    Department of Neurology, Beth Israel Deaconess Medical Center Harvard Medical School, 330 Brookline Ave, Boston, MA 02215, USA
    Neurology 74:280-7. 2010
    ....
  14. ncbi request reprint Repetitive TMS of the motor cortex improves ipsilateral sequential simple finger movements
    M Kobayashi
    Laboratory for Magnetic Brain Stimulation, Department of Neurology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA
    Neurology 62:91-8. 2004
    ..The authors hypothesize that reducing cortical excitability of M1 by rTMS may improve motor performance in the ipsilateral hand by releasing the contralateral M1 from transcallosal inhibition...
  15. ncbi request reprint Absolute pitch and planum temporale
    J P Keenan
    Department of Neurology, Beth Israel Deaconess Medical Center, 330 Brookline Avenue, Boston, Massachusetts 02215, USA
    Neuroimage 14:1402-8. 2001
    ..This may explain why the increased PT asymmetry of AP musicians was not seen in the group of early beginning non-AP musicians...
  16. ncbi request reprint Congenital amusia: an auditory-motor feedback disorder?
    Jake Mandell
    Department of Neurology, Music and Neuroimaging Laboratory, Beth Israel Deaconess Medical Center and Harvard Medical School, 330 Brookline Avenue, Boston, MA 02215, USA
    Restor Neurol Neurosci 25:323-34. 2007
    ..The aim of our study was to identify candidate brain regions that might be associated with this disorder...
  17. ncbi request reprint Examining rhythm and melody processing in young children using FMRI
    K Overy
    Music and Neuroimaging Laboratory, Department of Neurology, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachusetts 02215, USA
    Ann N Y Acad Sci 1060:210-8. 2005
    ....
  18. ncbi request reprint Neural correlates of absolute pitch differ between blind and sighted musicians
    Nadine Gaab
    Neuroimaging Laboratory, Department of Neurology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, USA
    Neuroreport 17:1853-7. 2006
    ....
  19. ncbi request reprint The power of listening: auditory-motor interactions in musical training
    Amir Lahav
    The Music, Mind and Motion Lab, Boston University, 635 Commonwealth Ave, MA 02215, USA
    Ann N Y Acad Sci 1060:189-94. 2005
    ..In addition, we found preliminary evidence that passive listening to a newly learned musical piece can enhance motor performance in the absence of physical practice...
  20. pmc The HAT Score: a simple grading scale for predicting hemorrhage after thrombolysis
    M Lou
    Department of Neurology, Stroke Division, Beth Israel Deaconess Medical Center, 330 Brookline Avenue, Palmer 127, Boston, MA 02215, USA
    Neurology 71:1417-23. 2008
    ..To develop a grading scale to predict the risk of intracerebral hemorrhage (ICH) and prognosis after treatment with IV tissue-plasminogen activator (t-PA) in patients with ischemic stroke...
  21. ncbi request reprint The brain of musicians. A model for functional and structural adaptation
    G Schlaug
    Department of Neurology, Beth Israel Deaconess Medical Center and Harvard Medical School, 330 Brookline Ave, Boston, MA, USA
    Ann N Y Acad Sci 930:281-99. 2001
    ..This structure may undergo some form of functional plasticity that is possible only during a critical period of brain development...
  22. ncbi request reprint Sleep-dependent motor memory plasticity in the human brain
    M P Walker
    Sleep and Neuroimaging Laboratory, FD Feldberg 862, Department of Psychiatry, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02115, USA
    Neuroscience 133:911-7. 2005
    ..This evidence of an overnight, systems-level change in the representation of a motor memory holds important implications for acquiring real-life skills and in clinical rehabilitation following brain trauma, such as stroke...
  23. ncbi request reprint STAR MR angiography for rapid detection of vascular abnormalities in patients with acute cerebrovascular disease
    B Siewert
    Department of Radiology, Beth Isreal Hospital, Boston Mass, USA
    Stroke 28:1211-5. 1997
    ..The potential advantage of the technique is that angiographic images can be acquired in less than 1 minute...
  24. ncbi request reprint Markedly reduced apparent blood volume on bolus contrast magnetic resonance imaging as a predictor of hemorrhage after thrombolytic therapy for acute ischemic stroke
    David C Alsop
    Department of Radiology, Beth Israel Deaconess Medical Center, and Harvard Medical School, Boston, Mass 02215, USA
    Stroke 36:746-50. 2005
    ..This study sought to define characteristics of hemodynamic magnetic resonance imaging (MRI), which best predict hemorrhage...
  25. pmc White matter integrity in right hemisphere predicts pitch-related grammar learning
    Psyche Loui
    Beth Israel Deaconess Medical Center and Harvard Medical School, Department of Neurology, Boston, MA 02215, USA
    Neuroimage 55:500-7. 2011
    ..Results show that the right ventral arcuate fasciculus is important in pitch-based artificial grammar learning, and that brain structures subserving learning may be tied to the hemisphere that processes the stimulus more generally...
  26. pmc Noninvasive brain stimulation may improve stroke-related dysphagia: a pilot study
    Sandeep Kumar
    Department of Neurology, Stroke Division, Beth Israel Deaconess Medical Center and Harvard Medical School, 330 Brookline Avenue, Palmer 127 Boston, MA 02215, USA
    Stroke 42:1035-40. 2011
    ..In this study, we investigated whether noninvasive brain stimulation in combination with swallowing maneuvers facilitates swallowing recovery in dysphagic stroke patients during early stroke convalescence...
  27. ncbi request reprint Clinical and vascular outcome in internal carotid artery versus middle cerebral artery occlusions after intravenous tissue plasminogen activator
    Italo Linfante
    Department of Neurology, Beth Israel Deaconess Medical Center, Boston, Mass 02115, USA
    Stroke 33:2066-71. 2002
    ....
  28. pmc Enhanced cortical connectivity in absolute pitch musicians: a model for local hyperconnectivity
    Psyche Loui
    Department of Neurology, Beth Israel Deaconess Medical Center, Harvard Medical School, 330 Brookline Ave, Palmer 127, Boston, MA 02215, USA
    J Cogn Neurosci 23:1015-26. 2011
    ....
  29. ncbi request reprint Action representation of sound: audiomotor recognition network while listening to newly acquired actions
    Amir Lahav
    Department of Neurology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts 02215, USA
    J Neurosci 27:308-14. 2007
    ..These findings support the hypothesis of a "hearing-doing" system that is highly dependent on the individual's motor repertoire, gets established rapidly, and consists of Broca's area as its hub...
  30. ncbi request reprint The effect of musicianship on pitch memory in performance matched groups
    Nadine Gaab
    Department of Neurology, Music and Neuroimaging Laboratory, Beth Israel Deaconess Medical Center, Boston, MA 02215, USA
    Neuroreport 14:2291-5. 2003
    ..Non-musicians rely more on brain regions important for pitch discrimination while musicians prefer to use brain regions specialized in short-term memory and recall to perform well in this pitch memory task...
  31. pmc Tone deafness: a new disconnection syndrome?
    Psyche Loui
    Department of Neurology and Radiology, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA 02215, USA
    J Neurosci 29:10215-20. 2009
    ..By identifying white matter differences and their psychophysical correlates, results contribute to our understanding of how neural connectivity subserves behavior...
  32. doi request reprint Reducing the delay in thrombolysis: is it necessary to await the results of renal function tests before computed tomography perfusion and angiography in patients with code stroke?
    Manu Mehdiratta
    Stroke Division, Beth Israel Deaconess Medical Center, Boston, Massachusetts 02215, USA
    J Stroke Cerebrovasc Dis 17:273-5. 2008
    ....
  33. ncbi request reprint Predictors of hemorrhagic transformation after intravenous recombinant tissue plasminogen activator: prognostic value of the initial apparent diffusion coefficient and diffusion-weighted lesion volume
    Magdy Selim
    Department of Neurology, Division of Cerebrovascular Diseases, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Mass 02215, USA
    Stroke 33:2047-52. 2002
    ..We sought to examine which pretreatment DWI parameters and clinical data are predictive of ICH after intravenous thrombolysis...
  34. ncbi request reprint The stroke patient who woke up: clinical and radiological features, including diffusion and perfusion MRI
    John N Fink
    Beth Israel Deaconess Medical Center, Boston, Mass 02215, USA
    Stroke 33:988-93. 2002
    ..Functional imaging techniques may allow estimation of benefit and risk of acute stroke therapy. We compared the clinical and multimodal MRI findings of patients with uncertain stroke onset with those with known onset time...
  35. ncbi request reprint The effects of gender on the neural substrates of pitch memory
    Nadine Gaab
    Beth Israel Deaconess Medical Center and Harvard Medical School, USA
    J Cogn Neurosci 15:810-20. 2003
    ..These data indicate that similar to language studies, males rely more on left lateralized hemispheric processing even for basic pitch tasks...
  36. ncbi request reprint Brain mapping in musicians with focal task-specific dystonia
    Michael E Charness
    Department of Neurology, Harvard Medical School, Department of Neurology, Brigham and Women s Hospital, Neurology Service, Veterans Affairs Boston Healthcare System, Boston, Massachusetts, USA
    Adv Neurol 94:231-8. 2004
  37. ncbi request reprint Shared and distinct neural correlates of singing and speaking
    Elif Ozdemir
    Music and Neuroimaging Laboratory, Beth Israel Deaconess Medical Center Harvard Medical School, 330 Brookline Ave, Palmer 127, Boston, MA 02215, USA
    Neuroimage 33:628-35. 2006
    ....
  38. ncbi request reprint Specialization of the specialized in features of external human brain morphology
    Marc Bangert
    Department of Neurology, Beth Israel Deaconess Medical Center and Harvard Medical School, 330 Brookline Ave, Boston, MA 02215, USA
    Eur J Neurosci 24:1832-4. 2006
    ..Musicians had a more pronounced OS expression than non-musicians, with keyboard-players showing a left and string-players a right hemisphere advantage. This suggests a differential brain adaptation depending on instrument played...
  39. pmc Investigating musical disorders with diffusion tensor imaging: a comparison of imaging parameters
    Psyche Loui
    Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachusetts, USA
    Ann N Y Acad Sci 1169:121-5. 2009
    ..Results were robust to variations in imaging parameters and emphasize the importance of brain connectivity in para-linguistic processes, such as music...
  40. ncbi request reprint Is the association of National Institutes of Health Stroke Scale scores and acute magnetic resonance imaging stroke volume equal for patients with right- and left-hemisphere ischemic stroke?
    John N Fink
    Beth Israel Deaconess Medical Center, Boston, Mass, USA
    Stroke 33:954-8. 2002
    ..The aim of this study was to investigate whether the relationship between acute NIHSS score and acute stroke volume as determined by acute diffusion- and perfusion-weighted MRI (DWI and PWI) differs between right- and left-sided stroke...
  41. ncbi request reprint Functional anatomy of pitch memory--an fMRI study with sparse temporal sampling
    Nadine Gaab
    Department of Neurology, Music and Neuroimaging Laboratory, Beth Israel Deaconess Medical Center and Harvard Medical School, 330 Brookline Avenue, Boston, MA 02215, USA
    Neuroimage 19:1417-26. 2003
    ..The SMG and the dorsolateral cerebellum may play a critical role in short-term storage of pitch information and the continuous pitch discrimination necessary for performing this pitch memory task...
  42. ncbi request reprint Improvement-related functional plasticity following pitch memory training
    Nadine Gaab
    Department of Neurology, Neuroimaging Laboratory, Beth Israel Deaconess Medical Center and Harvard Medical School, 330 Brookline Avenue, Boston, MA 02215, USA
    Neuroimage 31:255-63. 2006
    ..It is most likely that the activation of the SMG reflects its importance in the short-term storage of auditory material, and it was this activation that best differentiated between subjects' levels of performance...
  43. ncbi request reprint The influence of sleep on auditory learning: a behavioral study
    Nadine Gaab
    Department of Neurology, Music and Neuroimaging Laboratory, Beth Israel Deaconess Medical Center and Harvard Medical School, 330 Brookline Avenue, Boston, MA 02215, USA
    Neuroreport 15:731-4. 2004
    ..These data add to the growing literature describing sleep-dependent learning throughout sensory and motor domains...
  44. ncbi request reprint Absolute pitch in blind musicians
    Roy H Hamilton
    Department of Neurology, Beth Israel Deaconess Medical Center, 330 Brookline Avenue, Palmer 1, Boston, MA 02215, USA
    Neuroreport 15:803-6. 2004
    ..This suggests that neural mechanisms underlying AP in blind musicians could differ from those in sighted musicians...
  45. ncbi request reprint Arterial occlusive lesions recanalize more frequently in women than in men after intravenous tissue plasminogen activator administration for acute stroke
    Sean I Savitz
    Division of Cerebrovascular Disease, Beth Israel Deaconess Medical Center, Harvard Medical School, 330 Brookline Ave, Palmer 127, Boston, MA 02215, USA
    Stroke 36:1447-51. 2005
    ..Coagulation and fibrinolysis differ between sexes. These findings prompted us to investigate possible gender differences in arterial recanalization after intravenous tissue plasminogen activator (IV tPA)...
  46. ncbi request reprint Are there pre-existing neural, cognitive, or motoric markers for musical ability?
    Andrea Norton
    Department of Neurology, Beth Israel Deaconess Medical Center, Harvard Medical School, USA
    Brain Cogn 59:124-34. 2005
    ....
  47. ncbi request reprint Diffusion- and perfusion-weighted MRI patterns in borderzone infarcts
    C J Chaves
    Stroke Division, Department of Neurology, Beth Israel Deaconess Medical Center, Boston, MA 02115, USA
    Stroke 31:1090-6. 2000
    ..We investigated whether combined diffusion-weighted imaging (DWI) and perfusion-weighted imaging (PWI) could identify pathophysiologically meaningful categories of borderzone infarcts...
  48. ncbi request reprint Repetitive TMS temporarily alters brain diffusion
    F M Mottaghy
    Department of Neurology, Beth Israel Deaconess Medical Center, Boston, MA, USA
    Neurology 60:1539-41. 2003
    ..These findings provide a physiologic correlate to the reported behavioral consequences of off-line 1-Hz rTMS and reveal the transitory nature of the effects...
  49. ncbi request reprint Multiple acute stroke syndrome: marker of embolic disease?
    A E Baird
    Department of Neurology, Beth Israel Deaconess Medical Center, and Harvard Medical School, Boston, MA 02215, USA
    Neurology 54:674-8. 2000
    ..To determine the frequency and etiologic significance of multiple acute ischemic lesions in stroke...
  50. ncbi request reprint Age-related differences in movement representation
    S Hutchinson
    Neuroimaging Laboratory, Department of Neurology, Beth Israel Deaconess Medical Center, Boston, Massachusetts 02215, USA
    Neuroimage 17:1720-8. 2002
    ..This study has important implications for functional imaging experiments of neurological disorders in older subjects...
  51. pmc Atraumatic convexal subarachnoid hemorrhage: clinical presentation, imaging patterns, and etiologies
    S Kumar
    Department of Neurology, Stroke Division, Beth Israel Deaconess Medical Center, Boston, MA 02215, USA
    Neurology 74:893-9. 2010
    ..To identify patterns of clinical presentation, imaging findings, and etiologies in a cohort of hospitalized patients with localized nontraumatic convexal subarachnoid hemorrhage...
  52. ncbi request reprint Reciprocal modulation and attenuation in the prefrontal cortex: an fMRI study on emotional-cognitive interaction
    Georg Northoff
    Laboratory for Magnetic Brain Stimulation, Division of Behavioral Neurology, Department of Neurology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, USA
    Hum Brain Mapp 21:202-12. 2004
    ..Reciprocal modulation and attenuation in medial and lateral prefrontal cortex might constitute the neurophysiologic basis for emotional-cognitive interaction as observed in both healthy and psychiatric subjects...
  53. pmc Practicing a musical instrument in childhood is associated with enhanced verbal ability and nonverbal reasoning
    Marie Forgeard
    Department of Neurology, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachusetts, USA
    PLoS ONE 3:e3566. 2008
    ..In this study we investigated the association between instrumental music training in childhood and outcomes closely related to music training as well as those more distantly related...
  54. doi request reprint Modulating activity in the motor cortex affects performance for the two hands differently depending upon which hemisphere is stimulated
    Bradley W Vines
    Department of Neurology, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA 02215, USA
    Eur J Neurosci 28:1667-73. 2008
    ..These results provide evidence for a hemispheric asymmetry in the ipsilateral effects of modulating excitability in the motor cortex and may be important for clinical research on motor recovery...
  55. ncbi request reprint Seizure at stroke onset: should it be an absolute contraindication to thrombolysis?
    Magdy Selim
    Department of Neurology, Division of Cerebrovascular Diseases, Beth Israel Deaconess Medical Center, Boston, MA, USA
    Cerebrovasc Dis 14:54-7. 2002
    ..Magnetic resonance imaging (MRI) with diffusion- (DWI) and perfusion-weighted images (PWI) and angiography (MRA) can be used to confirm the diagnosis of an acute ischemic process in the presence of concurrent seizures...
  56. pmc Renal function predicts survival in patients with acute ischemic stroke
    Elizabeth Mostofsky
    Cardiovascular Epidemiology Research Unit, Department of Medicine, Beth Israel Deaconess Medical Center, Boston, MA 02115, USA
    Cerebrovasc Dis 28:88-94. 2009
    ..Among patients with acute ischemic stroke, impaired kidney function has been shown to increase the mortality risk, but the shape of this relationship has not been evaluated in detail...
  57. ncbi request reprint Imaging melody and rhythm processing in young children
    Katie Overy
    Music and Neuroimaging Laboratory, Department of Neurology, Harvard Medical School, 330 Brookline Ave, Boston, MA 02215, USA
    Neuroreport 15:1723-6. 2004
    ..These results suggest that hemispheric specialization for musical processing may develop with age...
  58. doi request reprint Association between serum ferritin level and perihematoma edema volume in patients with spontaneous intracerebral hemorrhage
    Manu Mehdiratta
    Department of Neurology, Harvard Medical School, Beth Israel Deaconess Medical Center, Boston, Mass 02215, USA
    Stroke 39:1165-70. 2008
    ..We undertook this exploratory study to investigate the association of serum ferritin, as an indicator of body iron load, with perihematoma edema after ICH...
  59. ncbi request reprint Cerebellar volume of musicians
    Siobhan Hutchinson
    Department of Neurology, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA 02215, USA
    Cereb Cortex 13:943-9. 2003
    ....
  60. ncbi request reprint Adults and children processing music: an fMRI study
    Stefan Koelsch
    Music and Neuroimaging Laboratory, Department of Neurology, Beth Israel Deaconess, Medical Center and Harvard Medical School, Boston, MA 02215, USA
    Neuroimage 25:1068-76. 2005
    ..In both adults and children, musical training was correlated with stronger activations in the frontal operculum and the anterior portion of the superior temporal gyrus...
  61. ncbi request reprint Dissociable networks for the expectancy and perception of emotional stimuli in the human brain
    Felix Bermpohl
    Center for Non Invasive Brain Stimulation, Department of Neurology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02132, USA
    Neuroimage 30:588-600. 2006
    ..This dissociation may reflect a distinction between anticipatory and perceptive components of emotional stimulus processing...
  62. ncbi request reprint Diffusion-weighted imaging and National Institutes of Health Stroke Scale in the acute phase of posterior-circulation stroke
    I Linfante
    Division of Cerebrovascular Diseases, Department of Neurology, Beth Israel Deaconess Medical Center, East Campus DA 779, 330 Brookline Ave, Boston, MA 02115, USA
    Arch Neurol 58:621-8. 2001
    ..Correlation between NIHSS score and lesion volume in posterior-circulation infarcts is unknown...
  63. ncbi request reprint Antiplatelets, ACE inhibitors, and statins combination reduces stroke severity and tissue at risk
    S Kumar
    Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA
    Neurology 66:1153-8; discussion 1135. 2006
    ..The authors examined whether combination therapy with these agents has additive protective effects in reducing ischemic stroke severity...
  64. pmc Alcohol and acute ischemic stroke onset: the stroke onset study
    Elizabeth Mostofsky
    Cardiovascular Epidemiology Research Unit, Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Mass 02215, USA
    Stroke 41:1845-9. 2010
    ....
  65. pmc From music making to speaking: engaging the mirror neuron system in autism
    Catherine Y Wan
    Department of Neurology, Music and Neuroimaging Laboratory, Beth Israel Deaconess Medical Center and Harvard Medical School, 330 Brookline Avenue, Boston, MA 02215, USA
    Brain Res Bull 82:161-8. 2010
    ..Thus, interventions incorporating methods of music making may offer a promising approach for facilitating expressive language in otherwise nonverbal children with autism...
  66. ncbi request reprint Ipsilateral motor cortex activation on functional magnetic resonance imaging during unilateral hand movements is related to interhemispheric interactions
    Masahito Kobayashi
    Laboratory for Magnetic Brain Stimulation, Department of Neurology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA
    Neuroimage 20:2259-70. 2003
    ..Instead, IpsiLM1 may reveal an enhanced interhemispheric inhibition from the right hemisphere upon the left to suppress superfluous, excessive activation...
  67. ncbi request reprint Contralateral and ipsilateral motor effects after transcranial direct current stimulation
    Bradley W Vines
    Neuroimaging Laboratory, Department of Neurology, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachusetts 02215, USA
    Neuroreport 17:671-4. 2006
    ..This outcome provides evidence for the role of interhemispheric inhibition in corticomotor functioning, and also has implications for treatment methods aimed at facilitating motor recovery after stroke...
  68. pmc Melodic intonation therapy: shared insights on how it is done and why it might help
    Andrea Norton
    Music, Stroke Recovery, and Neuroimaging Laboratory, Beth Israel Deaconess Medical Center Harvard Medical School, Boston, Massachusetts 02215, USA
    Ann N Y Acad Sci 1169:431-6. 2009
    ..Here we share those observations, our additions to the protocol that aim to enhance MIT's benefit, and the rationale that supports them...
  69. ncbi request reprint How do we modulate our emotions? Parametric fMRI reveals cortical midline structures as regions specifically involved in the processing of emotional valences
    Alexander Heinzel
    Behavioral Neurology Unit, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston 02215, USA
    Brain Res Cogn Brain Res 25:348-58. 2005
    ..We conclude that the psychological concept of emotional valence may be related to neural processing in cortical midline regions...
  70. ncbi request reprint Attentional modulation of emotional stimulus processing: an fMRI study using emotional expectancy
    Felix Bermpohl
    Center for Non Invasive Brain Stimulation, Department of Neurology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, USA
    Hum Brain Mapp 27:662-77. 2006
    ..This enhancement effect is not present in neutral pictures and might parallel accentuated subjective feeling states...
  71. ncbi request reprint Brain structures differ between musicians and non-musicians
    Christian Gaser
    Department of Neurology, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachusetts 02215, USA
    J Neurosci 23:9240-5. 2003
    ..However, only future experiments can determine the relative contribution of predisposition and practice...
  72. ncbi request reprint Corpus callosum: musician and gender effects
    Dennis J Lee
    Department of Neurology, Beth Israel Deaconess Medical Center and Harvard Medical School, 330 Brookline Ave, Boston, MA 02215, USA
    Neuroreport 14:205-9. 2003
    ....
  73. pmc Testing for causality with transcranial direct current stimulation: pitch memory and the left supramarginal gyrus
    Bradley W Vines
    Neuroimaging Laboratory, Department of Neurology, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachusetts 02215, USA
    Neuroreport 17:1047-50. 2006
    ....
  74. ncbi request reprint Hand function improvement with low-frequency repetitive transcranial magnetic stimulation of the unaffected hemisphere in a severe case of stroke
    Paulo S Boggio
    Center for Non Invasive Brain Stimulation, Department of Neurology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts 02215, USA
    Am J Phys Med Rehabil 85:927-30. 2006
    ....
  75. pmc Air pollution and risk of stroke: underestimation of effect due to misclassification of time of event onset
    R Peter Lokken
    Department of Medicine, Cardiovascular Epidemiology Research Unit, Beth Israel Deaconess Medical Center, Boston, MA 02115, USA
    Epidemiology 20:137-42. 2009
    ..Epidemiologic studies linking ambient air pollution to the onset of acute cardiovascular events often rely on date of hospital admission for exposure assessment...
  76. pmc Imaging correlates of motor recovery from cerebral infarction and their physiological significance in well-recovered patients
    Dinesh G Nair
    Department of Neurology, Palmer 127, Beth Israel Deaconess Medical Center Harvard Medical School, 330, Brookline Avenue, Boston, MA 02215, USA
    Neuroimage 34:253-63. 2007
    ..Disinhibition of the contralesional hemisphere observed in a subgroup of our patients suggests persistent alterations in intracortical and transcallosal (interhemispheric) interactions, despite complete functional recovery...
  77. pmc Lesion load of the corticospinal tract predicts motor impairment in chronic stroke
    Lin L Zhu
    Department of Neurology, Beth Israel Deaconess Medical Center Harvard Medical School, 330 Brookline Avenue, Boston, MA 02215, USA
    Stroke 41:910-5. 2010
    ....
  78. ncbi request reprint Magnetic resonance imaging profiles predict clinical response to early reperfusion: the diffusion and perfusion imaging evaluation for understanding stroke evolution (DEFUSE) study
    Gregory W Albers
    Department of Neurology and Neurological Sciences and the Stanford Stroke Center, Stanford University Medical Center, Stanford, CA 94304, USA
    Ann Neurol 60:508-17. 2006
    ..To determine whether prespecified baseline magnetic resonance imaging (MRI) profiles can identify stroke patients who have a robust clinical response after early reperfusion when treated 3 to 6 hours after symptom onset...
  79. ncbi request reprint Initial motor impairment influences activation pattern of motor recovery
    Masahito Kobayashi
    Department of Neurosurgery, Keio University School of Medicine, Tokyo, Japan
    Neurol Res 28:849-52. 2006
    ..We investigated the functional magnetic resonance imaging (fMRI) activation pattern of a motor task in patients with acute subcortical lesions to examine the relationship between activation pattern and recovery of motor impairment...
  80. ncbi request reprint Shared networks for auditory and motor processing in professional pianists: evidence from fMRI conjunction
    Marc Bangert
    Institute of Music Physiology and Musicians Medicine, Hanover University of Music and Drama, Hohenzollernstrasse 47, D 30161 Hanover, Germany
    Neuroimage 30:917-26. 2006
    ..This network is comprised of dorsolateral and inferior frontal cortex (including Broca's area), the superior temporal gyrus (Wernicke's area), the supramarginal gyrus, and supplementary motor and premotor areas...
  81. ncbi request reprint Evaluation of the clinical-diffusion and perfusion-diffusion mismatch models in DEFUSE
    Maarten G Lansberg
    Stanford Stroke Center, Stanford University Medical Center, Palo Alto, CA 94304, USA
    Stroke 38:1826-30. 2007
    ..The clinical-diffusion mismatch (CDM) model is an alternative method that is technically less challenging because it does not require perfusion-weighted imaging. This study is an evaluation of these 2 models in the DEFUSE dataset...
  82. pmc Action-perception mismatch in tone-deafness
    Psyche Loui
    Curr Biol 18:R331-2. 2008
  83. pmc Relationships between infarct growth, clinical outcome, and early recanalization in diffusion and perfusion imaging for understanding stroke evolution (DEFUSE)
    Jean Marc Olivot
    Department of Neurology and Neurological Sciences and the Stanford Stroke Center, Stanford University Medical Center, 701 Welch Road, Suite 325, Palo Alto, CA 94304, USA
    Stroke 39:2257-63. 2008
    ..The purpose of this study was to determine the relationships between ischemic lesion growth, recanalization, and clinical response in stroke patients with and without a perfusion/diffusion mismatch...
  84. ncbi request reprint Gray matter differences between musicians and nonmusicians
    Christian Gaser
    Department of Psychiatry, University of Jena, Jena, Germany
    Ann N Y Acad Sci 999:514-7. 2003
    ....

Research Grants11

  1. Behavioral and Neural Correlates of Melodic Intonation Therapy
    Gottfried Schlaug; Fiscal Year: 2009
    ..Secondary outcome measures include correctly named items on standard picture naming tests, timed automatic speech, and linguistically-based measures of phrase and sentence analysis. Project Description Page 6 ..
  2. Behavioral and Neural Correlates of Melodic Intonation Therapy
    Gottfried Schlaug; Fiscal Year: 2010
    ..Secondary outcome measures include correctly named items on standard picture naming tests, timed automatic speech, and linguistically-based measures of phrase and sentence analysis. ..
  3. Neural Control of Vocal Production in Tone-Deafness
    Gottfried Schlaug; Fiscal Year: 2010
    ....
  4. Behavioral and Neural Correlates of Melodic Intonation Therapy
    Gottfried Schlaug; Fiscal Year: 2009
    ....
  5. Facilitators of Motor Recovery Following Stroke
    Gottfried Schlaug; Fiscal Year: 2007
    ..abstract_text> ..
  6. Neural Control of Vocal Production in Tone-Deafness
    Gottfried Schlaug; Fiscal Year: 2011
    ..By combining brain imaging with singing tests in tone-deaf and normal individuals, and simulating abnormal singing via non-invasive brain stimulation, the proposed research will identify and test the neural substrates of tone-deafness. ..