Debra Schaumberg

Summary

Affiliation: Harvard University
Country: USA

Publications

  1. ncbi Corneal transplantation in young children with congenital hereditary endothelial dystrophy. Multicenter Pediatric Keratoplasty Study
    D A Schaumberg
    Division of Preventive Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts 02215, USA
    Am J Ophthalmol 127:373-8. 1999
  2. ncbi Effect of intensive glycemic control on levels of markers of inflammation in type 1 diabetes mellitus in the diabetes control and complications trial
    Debra A Schaumberg
    Division of Preventive Medicine, Brigham and Womens Hospital, Boston, Mass, USA
    Circulation 111:2446-53. 2005
  3. ncbi Accumulated lead exposure and risk of age-related cataract in men
    Debra A Schaumberg
    Division of Preventive Medicine, Brigham and Women s Hospital, Boston, Mass 02215 1204, USA
    JAMA 292:2750-4. 2004
  4. ncbi Dietary glycemic load and risk of age-related cataract
    Debra A Schaumberg
    Division of Preventive Medicine and Nutrition, Harvard School of Public Health, 900 Commonwealth Avenue East, Boston, MA 02215, USA
    Am J Clin Nutr 80:489-95. 2004
  5. ncbi No effect of beta-carotene supplementation on risk of nonmelanoma skin cancer among men with low baseline plasma beta-carotene
    Debra A Schaumberg
    Division of Preventive Medicine, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, 900 Commonwealth Avenue East, Boston, MA 02215, USA
    Cancer Epidemiol Biomarkers Prev 13:1079-80. 2004
  6. pmc High-sensitivity C-reactive protein, other markers of inflammation, and the incidence of macular degeneration in women
    Debra A Schaumberg
    Division of Preventive Medicine, 900 Commonwealth Ave E, Boston, MA 02215, USA
    Arch Ophthalmol 125:300-5. 2007
  7. pmc Prevalence of dry eye disease among US men: estimates from the Physicians' Health Studies
    Debra A Schaumberg
    Division of Preventive Medicine, Brigham and Women s Hospital, Harvard Medical School, 900 Commonwealth Ave E, Boston, MA 02215, USA
    Arch Ophthalmol 127:763-8. 2009
  8. pmc Prospective study of common variants in the retinoic acid receptor-related orphan receptor α gene and risk of neovascular age-related macular degeneration
    Debra A Schaumberg
    Division of Preventive Medicine, Department of Medicine, Brigham and Women s Hospital, Boston, MA 02215, USA
    Arch Ophthalmol 128:1462-71. 2010
  9. ncbi A prospective study of 2 major age-related macular degeneration susceptibility alleles and interactions with modifiable risk factors
    Debra A Schaumberg
    Division of Preventive Medicine, Brigham and Women s Hospital, Boston, Mass, USA
    Arch Ophthalmol 125:55-62. 2007
  10. ncbi Development and validation of a short global dry eye symptom index
    Debra A Schaumberg
    Schepens Eye Research Institute, Harvard Medical School, Boston, Massachusetts 02215, USA
    Ocul Surf 5:50-7. 2007

Research Grants

Detail Information

Publications32

  1. ncbi Corneal transplantation in young children with congenital hereditary endothelial dystrophy. Multicenter Pediatric Keratoplasty Study
    D A Schaumberg
    Division of Preventive Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts 02215, USA
    Am J Ophthalmol 127:373-8. 1999
    ....
  2. ncbi Effect of intensive glycemic control on levels of markers of inflammation in type 1 diabetes mellitus in the diabetes control and complications trial
    Debra A Schaumberg
    Division of Preventive Medicine, Brigham and Womens Hospital, Boston, Mass, USA
    Circulation 111:2446-53. 2005
    ..The present study examined the effect of intensive therapy on levels of several markers of inflammation that have been linked to risk of CVD...
  3. ncbi Accumulated lead exposure and risk of age-related cataract in men
    Debra A Schaumberg
    Division of Preventive Medicine, Brigham and Women s Hospital, Boston, Mass 02215 1204, USA
    JAMA 292:2750-4. 2004
    ..Several studies have documented the presence of lead in lenses with cataract. The intrusion of lead into the lens may alter lens redox status and cause protein conformational changes that decrease lens transparency...
  4. ncbi Dietary glycemic load and risk of age-related cataract
    Debra A Schaumberg
    Division of Preventive Medicine and Nutrition, Harvard School of Public Health, 900 Commonwealth Avenue East, Boston, MA 02215, USA
    Am J Clin Nutr 80:489-95. 2004
    ..Although hyperglycemia is a risk factor for cataract, there is no information on the potential effect of a high dietary glycemic load on the incidence of age-related cataract...
  5. ncbi No effect of beta-carotene supplementation on risk of nonmelanoma skin cancer among men with low baseline plasma beta-carotene
    Debra A Schaumberg
    Division of Preventive Medicine, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, 900 Commonwealth Avenue East, Boston, MA 02215, USA
    Cancer Epidemiol Biomarkers Prev 13:1079-80. 2004
  6. pmc High-sensitivity C-reactive protein, other markers of inflammation, and the incidence of macular degeneration in women
    Debra A Schaumberg
    Division of Preventive Medicine, 900 Commonwealth Ave E, Boston, MA 02215, USA
    Arch Ophthalmol 125:300-5. 2007
    ..To investigate whether high-sensitivity C-reactive protein (hsCRP) and other biomarkers of inflammation predict age-related macular degeneration (AMD)...
  7. pmc Prevalence of dry eye disease among US men: estimates from the Physicians' Health Studies
    Debra A Schaumberg
    Division of Preventive Medicine, Brigham and Women s Hospital, Harvard Medical School, 900 Commonwealth Ave E, Boston, MA 02215, USA
    Arch Ophthalmol 127:763-8. 2009
    ..To estimate the prevalence and risk factors for dry eye disease (DED) among US men...
  8. pmc Prospective study of common variants in the retinoic acid receptor-related orphan receptor α gene and risk of neovascular age-related macular degeneration
    Debra A Schaumberg
    Division of Preventive Medicine, Department of Medicine, Brigham and Women s Hospital, Boston, MA 02215, USA
    Arch Ophthalmol 128:1462-71. 2010
    ..We aimed to determine if common variants in RORA predict future risk of neovascular AMD...
  9. ncbi A prospective study of 2 major age-related macular degeneration susceptibility alleles and interactions with modifiable risk factors
    Debra A Schaumberg
    Division of Preventive Medicine, Brigham and Women s Hospital, Boston, Mass, USA
    Arch Ophthalmol 125:55-62. 2007
    ....
  10. ncbi Development and validation of a short global dry eye symptom index
    Debra A Schaumberg
    Schepens Eye Research Institute, Harvard Medical School, Boston, Massachusetts 02215, USA
    Ocul Surf 5:50-7. 2007
    ..The results are encouraging and suggest that further refinement and testing of the SANDE questionnaire in larger populations may result in a reliable questionnaire to detect change in irritative symptoms over time...
  11. ncbi Hormone replacement therapy and dry eye syndrome
    D A Schaumberg
    Division of Preventive Medicine, Brigham and Women s Hospital, Harvard Medical School, 900 Commonwealth Ave E, Boston, MA 02215, USA
    JAMA 286:2114-9. 2001
    ..Some research suggests that estrogen may have detrimental effects on the tear film and could influence the development of dry eye syndrome, but few data are available on this relationship...
  12. pmc Body mass index and the incidence of visually significant age-related maculopathy in men
    D A Schaumberg
    Division of Preventive Medicine, Brigham and Women s Hospital, 900 Commonwealth Ave E, Boston, MA 02215, USA
    Arch Ophthalmol 119:1259-65. 2001
    ..Reports have suggested relationships of body weight with age-related maculopathy (ARM), particularly its nonneovascular (dry) forms, but results are inconsistent and prospective data are scarce...
  13. pmc A prospective assessment of the Y402H variant in complement factor H, genetic variants in C-reactive protein, and risk of age-related macular degeneration
    Debra A Schaumberg
    Division of Preventive Medicine, Center for Cardiovascular Disease Prevention, Brigham and Women s Hospital, and Department of Ophthalmology, Schepens Eye Research Institute, Harvard Medical School, Boston, MA 02215, USA
    Invest Ophthalmol Vis Sci 47:2336-40. 2006
    ..Although plasma CRP levels have been related to AMD and plasma CRP levels are partly determined by genetic variation, there is no information on whether genetic variants in CRP are associated with AMD...
  14. ncbi Predictors of prolonged length of stay after major elective head and neck surgery
    Nicolas Y Busaba
    Division of Otolaryngology, VA Boston Healthcare System, Boston, Massachusetts, USA
    Laryngoscope 117:1756-63. 2007
    ....
  15. doi Menopausal and reproductive factors and risk of age-related macular degeneration
    Diane Feskanich
    Channing Laboratory, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, Massachusetts 02115, USA
    Arch Ophthalmol 126:519-24. 2008
    ..To investigate whether estrogen exposures are associated with lower risks of age-related macular degeneration (AMD)...
  16. ncbi Fruit and vegetable intake and the risk of cataract in women
    William G Christen
    Division of Preventive Medicine, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, MA, USA
    Am J Clin Nutr 81:1417-22. 2005
    ..Prospective data on cataract in relation to total fruit and vegetable intake are limited...
  17. pmc Inflammation and progressive nephropathy in type 1 diabetes in the diabetes control and complications trial
    Julie Lin
    Renal Division, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts, USA
    Diabetes Care 31:2338-43. 2008
    ..Early albuminuria probably reflects vascular endothelial dysfunction, which may be mediated in part by chronic inflammation...
  18. ncbi Prevalence of dry eye syndrome among US women
    Debra A Schaumberg
    Division of Preventive Medicine, Brigham and Women s Hospital, Schepens Eye Research Institute, Massachusetts Eye and Ear Infirmary, and Department of Medicine, Harvard Medical School, Boston, MA 02215, USA
    Am J Ophthalmol 136:318-26. 2003
    ..However, there are few studies describing the magnitude of the problem in women and how this may vary with demographic characteristics...
  19. ncbi Do estrogen and progesterone play a role in the dry eye of Sjögren's syndrome?
    Tomo Suzuki
    Schepens Eye Research Institute, Boston, Massachusetts 02114, USA
    Ann N Y Acad Sci 966:223-5. 2002
  20. ncbi Androgen deficiency, Meibomian gland dysfunction, and evaporative dry eye
    David A Sullivan
    Schepens Eye Research Institute, Boston, Massachusetts 02114, USA
    Ann N Y Acad Sci 966:211-22. 2002
    ..The following studies were designed to test these predictions...
  21. pmc Impact of dry eye syndrome on vision-related quality of life
    Biljana Miljanovic
    Division of Preventive Medicine, Brigham and Women s Hospital, Boston, Massachusetts, USA
    Am J Ophthalmol 143:409-15. 2007
    ..To evaluate the impact of dry eye syndrome (DES) on vision-associated quality of life...
  22. pmc Comparison of mucin levels at the ocular surface of postmenopausal women with and without a history of dry eye
    Ilene K Gipson
    Schepens Eye Research Institute and Department of Ophthalmology, Harvard Medical School, Boston, MA 02114, USA
    Cornea 30:1346-52. 2011
    ....
  23. pmc Relation between dietary n-3 and n-6 fatty acids and clinically diagnosed dry eye syndrome in women
    Biljana Miljanovic
    Division of Preventive Medicine, Brigham and Women s Hospital, Boston, MA 02215, USA
    Am J Clin Nutr 82:887-93. 2005
    ..Dry eye syndrome (DES) is a prevalent condition, but information on risk or protective factors is lacking...
  24. ncbi A prospective study of serum lipids and risk of diabetic macular edema in type 1 diabetes
    Biljana Miljanovic
    Division of Preventive Medicine, Brigham and Women s Hospital, Harvard Medical School, 900 Commonwealth Ave East, Boston, MA 02215, USA
    Diabetes 53:2883-92. 2004
    ..Lipid-lowering treatment among type 1 diabetic subjects, recommended to prevent cardiovascular disease, may also decrease risk of CSME, an important cause of vision loss...
  25. ncbi Epidemiology of dry eye syndrome
    Debra A Schaumberg
    Division of Preventive Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts, USA
    Adv Exp Med Biol 506:989-98. 2002
  26. doi Modulation of integrin alpha4beta1 (VLA-4) in dry eye disease
    Tatiana Ecoiffier
    Schepens Eye Research Institute, Harvard Medical School, Boston, MA 02114, USA
    Arch Ophthalmol 126:1695-9. 2008
    ..To study the effect of topical application of very late antigen 4 (VLA-4) small-molecule antagonist (anti-VLA-4 sm) in a mouse model of dry eye disease...
  27. ncbi Validation and repeatability of a short questionnaire for dry eye syndrome
    Abha Gulati
    Schepens Eye Research Institute, Harvard Medical School, Boston, Massachusetts 02215, USA
    Am J Ophthalmol 142:125-131. 2006
    ....
  28. ncbi Microdebrider tonsillotomy vs electrosurgical tonsillectomy: a randomized, double-blind, paired control study of postoperative pain
    Matthew T Lister
    Department of Otolaryngology, Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, USA
    Arch Otolaryngol Head Neck Surg 132:599-604. 2006
    ..To examine whether microdebrider intracapsular tonsillotomy (MT) results in less postoperative pain compared with electrosurgical extracapsular tonsillectomy (ET)...
  29. doi Preoperative characteristics and a potential mechanism of chronic dry eye after LASIK
    Keiko Konomi
    Schepens Eye Research Institute, 20 Staniford Street, Boston, MA 02114, USA
    Invest Ophthalmol Vis Sci 49:168-74. 2008
    ..To determine whether measurable preoperative characteristics predispose patients to chronic dry eye after laser in situ keratomileusis (LASIK)...
  30. doi Topical omega-3 and omega-6 fatty acids for treatment of dry eye
    Saadia Rashid
    Schepens Eye Research Institute, 20 Staniford St, Boston, MA 02114, USA
    Arch Ophthalmol 126:219-25. 2008
    ..To study the efficacy of topical application of alpha-linolenic acid (ALA) and linoleic acid (LA) for dry eye treatment...
  31. ncbi Assessment of visual function after corneal transplantation: the quality of life and psychometric assessment after corneal transplantation (Q-PACT) study
    Flavia Mendes
    Massachusetts Eye and Ear Infirmary and Schepens Eye Research Institute, Harvard Medical School, Boston, Massachusetts 02114, USA
    Am J Ophthalmol 135:785-93. 2003
    ..Many patients with successful corneal grafts have poor vision postoperatively. This study evaluates changes in vision-related quality of life after penetrating keratoplasty (PK)...
  32. doi The changing times in dry eye research
    Kelly K Nichols
    Optom Vis Sci 85:613-4. 2008

Research Grants7

  1. Molecular Risk Factors for Age-Related Maculopathy
    Debra Schaumberg; Fiscal Year: 2004
    ..abstract_text> ..
  2. Genetic Epidemiology of Age-Related Macular Degeneration
    Debra Schaumberg; Fiscal Year: 2007
    ....
  3. Genetic Epidemiology of Age-Related Macular Degeneration
    Debra A Schaumberg; Fiscal Year: 2010
    ....