Research Topics
Species | Debra SchaumbergSummaryAffiliation: Harvard University Country: USA Publications
Research Grants
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Detail Information
Publications
Corneal transplantation in young children with congenital hereditary endothelial dystrophy. Multicenter Pediatric Keratoplasty StudyD A Schaumberg
Division of Preventive Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts 02215, USA
Am J Ophthalmol 127:373-8. 1999....- Effect of intensive glycemic control on levels of markers of inflammation in type 1 diabetes mellitus in the diabetes control and complications trialDebra A Schaumberg
Division of Preventive Medicine, Brigham and Womens Hospital, Boston, Mass, USA
Circulation 111:2446-53. 2005..The present study examined the effect of intensive therapy on levels of several markers of inflammation that have been linked to risk of CVD... - Accumulated lead exposure and risk of age-related cataract in menDebra A Schaumberg
Division of Preventive Medicine, Brigham and Women s Hospital, Boston, Mass 02215 1204, USA
JAMA 292:2750-4. 2004..Several studies have documented the presence of lead in lenses with cataract. The intrusion of lead into the lens may alter lens redox status and cause protein conformational changes that decrease lens transparency... - Dietary glycemic load and risk of age-related cataractDebra A Schaumberg
Division of Preventive Medicine and Nutrition, Harvard School of Public Health, 900 Commonwealth Avenue East, Boston, MA 02215, USA
Am J Clin Nutr 80:489-95. 2004..Although hyperglycemia is a risk factor for cataract, there is no information on the potential effect of a high dietary glycemic load on the incidence of age-related cataract... - No effect of beta-carotene supplementation on risk of nonmelanoma skin cancer among men with low baseline plasma beta-caroteneDebra A Schaumberg
Division of Preventive Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, 900 Commonwealth Avenue East, Boston, MA 02215, USA
Cancer Epidemiol Biomarkers Prev 13:1079-80. 2004 
High-sensitivity C-reactive protein, other markers of inflammation, and the incidence of macular degeneration in womenDebra A Schaumberg
Division of Preventive Medicine, 900 Commonwealth Ave E, Boston, MA 02215, USA
Arch Ophthalmol 125:300-5. 2007..To investigate whether high-sensitivity C-reactive protein (hsCRP) and other biomarkers of inflammation predict age-related macular degeneration (AMD)...- Prevalence of dry eye disease among US men: estimates from the Physicians' Health StudiesDebra A Schaumberg
Division of Preventive Medicine, Brigham and Women s Hospital, Harvard Medical School, 900 Commonwealth Ave E, Boston, MA 02215, USA
Arch Ophthalmol 127:763-8. 2009..To estimate the prevalence and risk factors for dry eye disease (DED) among US men... - Prospective study of common variants in the retinoic acid receptor-related orphan receptor α gene and risk of neovascular age-related macular degenerationDebra A Schaumberg
Division of Preventive Medicine, Department of Medicine, Brigham and Women s Hospital, Boston, MA 02215, USA
Arch Ophthalmol 128:1462-71. 2010..We aimed to determine if common variants in RORA predict future risk of neovascular AMD... - A prospective study of 2 major age-related macular degeneration susceptibility alleles and interactions with modifiable risk factorsDebra A Schaumberg
Division of Preventive Medicine, Brigham and Women s Hospital, Boston, Mass, USA
Arch Ophthalmol 125:55-62. 2007.... - Development and validation of a short global dry eye symptom indexDebra A Schaumberg
Schepens Eye Research Institute, Harvard Medical School, Boston, Massachusetts 02215, USA
Ocul Surf 5:50-7. 2007..The results are encouraging and suggest that further refinement and testing of the SANDE questionnaire in larger populations may result in a reliable questionnaire to detect change in irritative symptoms over time... - Hormone replacement therapy and dry eye syndromeD A Schaumberg
Division of Preventive Medicine, Brigham and Women s Hospital, Harvard Medical School, 900 Commonwealth Ave E, Boston, MA 02215, USA
JAMA 286:2114-9. 2001..Some research suggests that estrogen may have detrimental effects on the tear film and could influence the development of dry eye syndrome, but few data are available on this relationship... - Body mass index and the incidence of visually significant age-related maculopathy in menD A Schaumberg
Division of Preventive Medicine, Brigham and Women s Hospital, 900 Commonwealth Ave E, Boston, MA 02215, USA
Arch Ophthalmol 119:1259-65. 2001..Reports have suggested relationships of body weight with age-related maculopathy (ARM), particularly its nonneovascular (dry) forms, but results are inconsistent and prospective data are scarce... - A prospective assessment of the Y402H variant in complement factor H, genetic variants in C-reactive protein, and risk of age-related macular degenerationDebra A Schaumberg
Division of Preventive Medicine, Center for Cardiovascular Disease Prevention, Brigham and Women s Hospital, and Department of Ophthalmology, Schepens Eye Research Institute, Harvard Medical School, Boston, MA 02215, USA
Invest Ophthalmol Vis Sci 47:2336-40. 2006..Although plasma CRP levels have been related to AMD and plasma CRP levels are partly determined by genetic variation, there is no information on whether genetic variants in CRP are associated with AMD... - Predictors of prolonged length of stay after major elective head and neck surgeryNicolas Y Busaba
Division of Otolaryngology, VA Boston Healthcare System, Boston, Massachusetts, USA
Laryngoscope 117:1756-63. 2007.... 
Menopausal and reproductive factors and risk of age-related macular degenerationDiane Feskanich
Channing Laboratory, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, Massachusetts 02115, USA
Arch Ophthalmol 126:519-24. 2008..To investigate whether estrogen exposures are associated with lower risks of age-related macular degeneration (AMD)...- Fruit and vegetable intake and the risk of cataract in womenWilliam G Christen
Division of Preventive Medicine, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, MA, USA
Am J Clin Nutr 81:1417-22. 2005..Prospective data on cataract in relation to total fruit and vegetable intake are limited... - Inflammation and progressive nephropathy in type 1 diabetes in the diabetes control and complications trialJulie Lin
Renal Division, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts, USA
Diabetes Care 31:2338-43. 2008..Early albuminuria probably reflects vascular endothelial dysfunction, which may be mediated in part by chronic inflammation... - Prevalence of dry eye syndrome among US womenDebra A Schaumberg
Division of Preventive Medicine, Brigham and Women s Hospital, Schepens Eye Research Institute, Massachusetts Eye and Ear Infirmary, and Department of Medicine, Harvard Medical School, Boston, MA 02215, USA
Am J Ophthalmol 136:318-26. 2003..However, there are few studies describing the magnitude of the problem in women and how this may vary with demographic characteristics... - Do estrogen and progesterone play a role in the dry eye of Sjögren's syndrome?Tomo Suzuki
Schepens Eye Research Institute, Boston, Massachusetts 02114, USA
Ann N Y Acad Sci 966:223-5. 2002 - Androgen deficiency, Meibomian gland dysfunction, and evaporative dry eyeDavid A Sullivan
Schepens Eye Research Institute, Boston, Massachusetts 02114, USA
Ann N Y Acad Sci 966:211-22. 2002..The following studies were designed to test these predictions... - Impact of dry eye syndrome on vision-related quality of lifeBiljana Miljanovic
Division of Preventive Medicine, Brigham and Women s Hospital, Boston, Massachusetts, USA
Am J Ophthalmol 143:409-15. 2007..To evaluate the impact of dry eye syndrome (DES) on vision-associated quality of life... - Comparison of mucin levels at the ocular surface of postmenopausal women with and without a history of dry eyeIlene K Gipson
Schepens Eye Research Institute and Department of Ophthalmology, Harvard Medical School, Boston, MA 02114, USA
Cornea 30:1346-52. 2011.... - Relation between dietary n-3 and n-6 fatty acids and clinically diagnosed dry eye syndrome in womenBiljana Miljanovic
Division of Preventive Medicine, Brigham and Women s Hospital, Boston, MA 02215, USA
Am J Clin Nutr 82:887-93. 2005..Dry eye syndrome (DES) is a prevalent condition, but information on risk or protective factors is lacking... - A prospective study of serum lipids and risk of diabetic macular edema in type 1 diabetesBiljana Miljanovic
Division of Preventive Medicine, Brigham and Women's Hospital, Harvard Medical School, 900 Commonwealth Ave. East, Boston, MA 02215, USA
Diabetes 53:2883-92. 2004..Lipid-lowering treatment among type 1 diabetic subjects, recommended to prevent cardiovascular disease, may also decrease risk of CSME, an important cause of vision loss... - Epidemiology of dry eye syndromeDebra A Schaumberg
Division of Preventive Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA
Adv Exp Med Biol 506:989-98. 2002 - Modulation of integrin alpha4beta1 (VLA-4) in dry eye diseaseTatiana Ecoiffier
Schepens Eye Research Institute, Harvard Medical School, Boston, MA 02114, USA
Arch Ophthalmol 126:1695-9. 2008..To study the effect of topical application of very late antigen 4 (VLA-4) small-molecule antagonist (anti-VLA-4 sm) in a mouse model of dry eye disease... - Validation and repeatability of a short questionnaire for dry eye syndromeAbha Gulati
Schepens Eye Research Institute, Harvard Medical School, Boston, Massachusetts 02215, USA
Am J Ophthalmol 142:125-131. 2006..CONCLUSION: The short questionnaire for DES is a sensitive and repeatable tool that is easy to administer in large epidemiologic research studies as well as clinical research... - Microdebrider tonsillotomy vs electrosurgical tonsillectomy: a randomized, double-blind, paired control study of postoperative painMatthew T Lister
Department of Otolaryngology, Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, USA
Arch Otolaryngol Head Neck Surg 132:599-604. 2006..CONCLUSION: Microdebrider intracapsular tonsillotomy is significantly less painful compared with electrosurgical ET in children undergoing surgical intervention for obstructive tonsillar hypertrophy... - Preoperative characteristics and a potential mechanism of chronic dry eye after LASIKKeiko Konomi
Schepens Eye Research Institute, 20 Staniford Street, Boston, MA 02114, USA
Invest Ophthalmol Vis Sci 49:168-74. 2008..To determine whether measurable preoperative characteristics predispose patients to chronic dry eye after laser in situ keratomileusis (LASIK)... - Topical omega-3 and omega-6 fatty acids for treatment of dry eyeSaadia Rashid
Schepens Eye Research Institute, 20 Staniford St, Boston, MA 02114, USA
Arch Ophthalmol 126:219-25. 2008..To study the efficacy of topical application of alpha-linolenic acid (ALA) and linoleic acid (LA) for dry eye treatment... - Assessment of visual function after corneal transplantation: the quality of life and psychometric assessment after corneal transplantation (Q-PACT) studyFlavia Mendes
Massachusetts Eye and Ear Infirmary and Schepens Eye Research Institute, Harvard Medical School, Boston, Massachusetts 02114, USA
Am J Ophthalmol 135:785-93. 2003..Although most keratoplasties are done unilaterally in the setting of good visual acuity in the contralateral eye, for the majority of patients visual function improves after PK... - The changing times in dry eye researchKelly K Nichols
Optom Vis Sci 85:613-4. 2008
Research Grants
- Molecular Risk Factors for Age-Related MaculopathyDebra Schaumberg; Fiscal Year: 2004..abstract_text> ..
- Genetic Epidemiology of Age-Related Macular DegenerationDebra Schaumberg; Fiscal Year: 2007....
- Genetic Epidemiology of Age-Related Macular DegenerationDebra A Schaumberg; Fiscal Year: 2010....