Susan L Santangelo

Summary

Affiliation: Harvard University
Country: USA

Publications

  1. ncbi What is known about autism: genes, brain, and behavior
    Susan L Santangelo
    Psychiatric and Neurodevelopmental Genetics Unit, Center for Human Genetic Research, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02129, USA
    Am J Pharmacogenomics 5:71-92. 2005
  2. ncbi A discordant sib-pair linkage analysis of age-related macular degeneration
    Susan L Santangelo
    Psychiatric and Neurodevelopmental Genetics Unit, Center for Human Genetic Research, Massachusetts General Hospital, 149 13th Street, Charlestown, MA, USA
    Ophthalmic Genet 26:61-7. 2005
  3. ncbi Sex-specific association of a common variant of the XG gene with autism spectrum disorders
    Shun Chiao Chang
    Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts Department of Social and Behavioral Sciences, Harvard School of Public Health, Boston, Massachusetts
    Am J Med Genet B Neuropsychiatr Genet 162:742-50. 2013
  4. pmc Fertility therapies, infertility and autism spectrum disorders in the Nurses' Health Study II
    Kristen Lyall
    Department of Nutrition, Harvard School of Public Health, Boston, MA, USA
    Paediatr Perinat Epidemiol 26:361-72. 2012
  5. pmc Pregnancy complications and obstetric suboptimality in association with autism spectrum disorders in children of the Nurses' Health Study II
    Kristen Lyall
    Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts 02115, USA
    Autism Res 5:21-30. 2012
  6. pmc A genome-wide linkage and association scan reveals novel loci for autism
    Lauren A Weiss
    Center for Human Genetic Research, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts 02114, USA
    Nature 461:802-8. 2009
  7. pmc A genomewide scan for age-related macular degeneration provides evidence for linkage to several chromosomal regions
    Johanna M Seddon
    Ophthalmology Epidemiology Unit, Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, MA 02114, USA
    Am J Hum Genet 73:780-90. 2003
  8. ncbi The genetics of age-related macular degeneration: a review of progress to date
    Stephen Haddad
    Psychiatric and Neurodevelopmental Genetics Unit, Massachusetts General Hospital, Boston, 02114, USA
    Surv Ophthalmol 51:316-63. 2006
  9. pmc Paternal age increases the risk for autism in an Iranian population sample
    Roksana Sasanfar
    Department of Psychiatry, Harvard Medical School, Boston, MA, USA
    Mol Autism 1:2. 2010
  10. doi Association between microdeletion and microduplication at 16p11.2 and autism
    Lauren A Weiss
    Autism Consortium, Boston, USA
    N Engl J Med 358:667-75. 2008

Detail Information

Publications18

  1. ncbi What is known about autism: genes, brain, and behavior
    Susan L Santangelo
    Psychiatric and Neurodevelopmental Genetics Unit, Center for Human Genetic Research, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02129, USA
    Am J Pharmacogenomics 5:71-92. 2005
    ..The application of new techniques in autism research is being proposed, including the investigation of abnormal regulation of gene expression, proteomics, and the use of MRI and postmortem analysis of the brain...
  2. ncbi A discordant sib-pair linkage analysis of age-related macular degeneration
    Susan L Santangelo
    Psychiatric and Neurodevelopmental Genetics Unit, Center for Human Genetic Research, Massachusetts General Hospital, 149 13th Street, Charlestown, MA, USA
    Ophthalmic Genet 26:61-7. 2005
    ..Our prior genome scan in 511 affected sib-pairs and other relative pairs identified significant or suggestive linkage signals on chromosomes 1, 2, 3, 6, 8, 10, 12, 16, and 22...
  3. ncbi Sex-specific association of a common variant of the XG gene with autism spectrum disorders
    Shun Chiao Chang
    Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts Department of Social and Behavioral Sciences, Harvard School of Public Health, Boston, Massachusetts
    Am J Med Genet B Neuropsychiatr Genet 162:742-50. 2013
    ..Our results suggest that the pseudoautosomal boundary on Xp22.33/Yp11.31 may harbor male-specific genetic variants for ASD...
  4. pmc Fertility therapies, infertility and autism spectrum disorders in the Nurses' Health Study II
    Kristen Lyall
    Department of Nutrition, Harvard School of Public Health, Boston, MA, USA
    Paediatr Perinat Epidemiol 26:361-72. 2012
    ..An increasing number of women are utilizing fertility treatments, but little is known about their relation to autism spectrum disorders (ASD)...
  5. pmc Pregnancy complications and obstetric suboptimality in association with autism spectrum disorders in children of the Nurses' Health Study II
    Kristen Lyall
    Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts 02115, USA
    Autism Res 5:21-30. 2012
    ..Consistent with previous research, the general class of pregnancy complications was associated with ASD as a whole. Additional work will be required to more fully assess the role of gestational diabetes...
  6. pmc A genome-wide linkage and association scan reveals novel loci for autism
    Lauren A Weiss
    Center for Human Genetic Research, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts 02114, USA
    Nature 461:802-8. 2009
    ..The linkage regions reported here provide targets for rare variation screening whereas the discovery of a single novel association demonstrates the action of common variants...
  7. pmc A genomewide scan for age-related macular degeneration provides evidence for linkage to several chromosomal regions
    Johanna M Seddon
    Ophthalmology Epidemiology Unit, Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, MA 02114, USA
    Am J Hum Genet 73:780-90. 2003
    ..00001. The consistency of many of the other signals across both two-point and multipoint, as well as parametric and nonparametric, analyses indicate several other regions worthy of follow-up...
  8. ncbi The genetics of age-related macular degeneration: a review of progress to date
    Stephen Haddad
    Psychiatric and Neurodevelopmental Genetics Unit, Massachusetts General Hospital, Boston, 02114, USA
    Surv Ophthalmol 51:316-63. 2006
    ..Among these, apolipoprotein E (APOE) may be a minor risk locus. Additional genes will likely be identified, and future studies should explore the potential interactions of these genes with other genes as well as environmental factors...
  9. pmc Paternal age increases the risk for autism in an Iranian population sample
    Roksana Sasanfar
    Department of Psychiatry, Harvard Medical School, Boston, MA, USA
    Mol Autism 1:2. 2010
    ..Parental age has been shown to be associated with many disorders, such as schizophrenia, childhood cancer and fetal death. However, results from studies of parental age and autism are inconsistent...
  10. doi Association between microdeletion and microduplication at 16p11.2 and autism
    Lauren A Weiss
    Autism Consortium, Boston, USA
    N Engl J Med 358:667-75. 2008
    ..Autism spectrum disorder is a heritable developmental disorder in which chromosomal abnormalities are thought to play a role...
  11. pmc A QTL genome scan of the metabolic syndrome and its component traits
    Matthew B McQueen
    Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts, USA
    BMC Genet 4:S96. 2003
    ..We used genotype and phenotype data from the Framingham Heart Study to perform a full-genome scan for quantitative trait loci underlying the metabolic syndrome...
  12. doi Autism and serotonin transporter gene polymorphisms: a systematic review and meta-analysis
    Christine H Huang
    Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts, USA
    Am J Med Genet B Neuropsychiatr Genet 147:903-13. 2008
    ....
  13. pmc Maternal early life factors associated with hormone levels and the risk of having a child with an autism spectrum disorder in the nurses health study II
    Kristen Lyall
    Department of Epidemiology, Harvard School of Public Health, Boston, MA, USA
    J Autism Dev Disord 41:618-27. 2011
    ..54, 95% CI 1.18, 2.02, p = 0.0002) and BMI at age 18 of ≥30 (RR 2.03, 95% CI 1.34, 3.08, p = 0.0008) were significantly associated with increased risk of ASD. Further work should investigate the potential influence of these factors...
  14. pmc Brief report: no association between parental age and extreme social-communicative autistic traits in the general population
    Elise B Robinson
    Department of Epidemiology, Harvard School of Public Health, Simches Research Building, Boston, MA 02114, USA
    J Autism Dev Disord 41:1733-7. 2011
    ..Neither maternal nor paternal age was associated with extreme scores. These findings suggest that advanced parental age does not confer increased risk for extreme social and communication impairment assessed quantitatively...
  15. pmc Common genetic variation in the GAD1 gene and the entire family of DLX homeobox genes and autism spectrum disorders
    Shun Chiao Chang
    Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts, USA
    Am J Med Genet B Neuropsychiatr Genet 156:233-9. 2011
    ..Our observations, when taken together with previous findings, suggest that common genetic variation in the GAD1 and DLX genes is unlikely to play a critical role in ASD susceptibility...
  16. pmc Examination of NRCAM, LRRN3, KIAA0716, and LAMB1 as autism candidate genes
    Holli B Hutcheson
    Center for Human Genetics Research and Department of Molecular Physiology and Biophysics, Vanderbilt University Medical Center, Nashville, TN 37027, USA
    BMC Med Genet 5:12. 2004
    ....
  17. ncbi Meta-analysis of genome scans of age-related macular degeneration
    Sheila A Fisher
    Department of Medical and Molecular Genetics, Guy s, King s and St Thomas School of Medicine, King s College London, London SE1 9RT, UK
    Hum Mol Genet 14:2257-64. 2005
    ..Several of the regions identified here showed only weak evidence for linkage in the individual studies. These results will help prioritize regions for future positional and functional candidate gene studies in AMD...
  18. ncbi Intergenerational transmission of tobacco use and dependence: a transdisciplinary perspective
    Edmond D Shenassa
    Brown Medical School, Centers for Behavioral and Preventive Medicine, Providence, RI 02903, USA
    Nicotine Tob Res 5:S55-69. 2003
    ..Research gaps that exist between scientific disciplines are highlighted, and some directions for future research are suggested...