Research Topics
| E J SamelsonSummaryAffiliation: Harvard University Country: USA Publications
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Detail Information
Publications
The MOBILIZE Boston Study: design and methods of a prospective cohort study of novel risk factors for falls in an older populationSuzanne G Leveille
Division of General Medicine and Primary Care, Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA
BMC Geriatr 8:16. 2008....
Issues in conducting epidemiologic research among elders: lessons from the MOBILIZE Boston StudyElizabeth J Samelson
Institute for Aging Research, Hebrew SeniorLife, 1200 Centre Street, Boston, MA 02131, USA
Am J Epidemiol 168:1444-51. 2008..It is hoped that this paper will encourage and inform future epidemiologic research in this important segment of the population...
Increased plasma osteoprotegerin concentrations are associated with indices of bone strength of the hipElizabeth J Samelson
Institute for Aging Research, Hebrew SeniorLife, 1200 Centre Street, Boston, MA 02131, USA
J Clin Endocrinol Metab 93:1789-95. 2008..We conducted a cross-sectional study to evaluate the association between plasma OPG and femoral neck (FN) bone density (BMD) and geometry in a large cohort of women and men...
Vascular calcification in middle age and long-term risk of hip fracture: the Framingham StudyElizabeth J Samelson
Institute for Aging Research, Hebrew SeniorLife, Boston, Massachusetts 02131, USA
J Bone Miner Res 22:1449-54. 2007..This study examined the relation between severity of aortic calcification in middle-age years and subsequent risk of hip fracture in women and men in the population-based Framingham Study...
Incidence and risk factors for vertebral fracture in women and men: 25-year follow-up results from the population-based Framingham studyElizabeth J Samelson
Institute for Aging Research, Hebrew SeniorLife, Boston, MA 02131, USA
J Bone Miner Res 21:1207-14. 2006..Incidence was 24% in women and 10% in men. Few factors in middle-aged persons, except prevalent (moderate) fracture and alcohol consumption (in men), predicted long-term incidence of vertebral fracture...
Epidemiology of osteoporosisElizabeth J Samelson
Institute for Aging Research, Hebrew Senior Life, Harvard Medical School, 1200 Centre Street, Boston, MA 02131, USA
Curr Rheumatol Rep 8:76-83. 2006..This epidemiologic review describes the definition, pathogenesis, and risk factors, as well as the frequency and impact of osteoporosis, with particular emphasis upon hip fracture...
Reliability of vertebral fracture assessment using multidetector CT lateral scout views: the Framingham Osteoporosis StudyE J Samelson
Hebrew SeniorLife, Institute for Aging Research Boston, Boston, MA, USA
Osteoporos Int 22:1123-31. 2011..Agreement was fair to good for mild fractures, and agreement was good to excellent for more severe fractures. CT scout views are useful to assess vertebral fracture...
Identification of prevalent vertebral fractures using CT lateral scout views: a comparison of semi-automated quantitative vertebral morphometry and radiologist semi-quantitative gradingY M Kim
Center for Advanced Orthopaedic Studies, Beth Israel Deaconess Medical Center, Boston, MA, USA
Osteoporos Int 23:1007-16. 2012..The semi-automated morphometry method showed good to excellent agreement with the visual SQ grading by radiologists for identification of vertebral fractures...
Survival of aged nursing home residents with hip fractureSarah D Berry
Institute for Aging Research, Hebrew SeniorLife, Boston, Massachusetts, USA
J Gerontol A Biol Sci Med Sci 64:771-7. 2009..This study examined the effect of pre-fracture characteristics, hospital complications, and post-fracture complications on mortality in residents with hip fracture...
Intra-and inter-reader reliability of semi-automated quantitative morphometry measurements and vertebral fracture assessment using lateral scout views from computed tomographyY M Kim
Center for Advanced Orthopaedic Studies, Beth Israel Deaconess Medical Center, Boston, MA, USA
Osteoporos Int 22:2677-88. 2011..Reliability was excellent for vertebral height measurements, good for height ratios, and comparable to semi-quantitative grading by radiologists for identification of vertebral fractures...
Application of the National Osteoporosis Foundation Guidelines to postmenopausal women and men: the Framingham Osteoporosis StudyS D Berry
Institute for Aging Research, Hebrew SeniorLife, Boston, MA 02131, USA
Osteoporos Int 21:53-60. 2010..Given the high proportion of persons recommended for treatment, NOF Guidelines may need to be re-evaluated with respect to budget impact...
Competing risk of death: an important consideration in studies of older adultsSarah D Berry
Institute for Aging Research, Hebrew SeniorLife, Boston, Massachusetts 02131, USA
J Am Geriatr Soc 58:783-7. 2010..Use of a competing risk approach is critical to accurately determining disease risk for elderly individuals and therefore best inform clinical decision-making...
Optimizing the tracking of falls in studies of older participants: comparison of quarterly telephone recall with monthly falls calendars in the MOBILIZE Boston StudyMarian T Hannan
Institute for Aging Research, Hebrew SeniorLife, 1200 Centre Street, Boston, MA 02131 1097, USA
Am J Epidemiol 171:1031-6. 2010..Retrospective 3-month recall of falls resulted in underreporting of falls by as much as 25% compared with daily calendars. Calendars should be considered the preferred method of ascertaining falls in longitudinal studies...
Poor adherence to medications may be associated with fallsSarah D Berry
MD Institute for Aging Research, Hebrew SeniorLife, 1200 Centre Street, Boston, MA 02131, USA
J Gerontol A Biol Sci Med Sci 65:553-8. 2010....
Subsequent fracture in nursing home residents with a hip fracture: a competing risks approachSarah D Berry
Hebrew SeniorLife, Institute for Aging Research, Hebrew SeniorLife, Boston, Massachusetts 02131, USA
J Am Geriatr Soc 56:1887-92. 2008..To determine the incidence and predictors of subsequent fracture in nursing home residents with a hip fracture, accounting for the competing risk of death...
Effect of birth cohort on risk of hip fracture: age-specific incidence rates in the Framingham StudyElizabeth J Samelson
Boston University Arthritis Center, Boston, Mass, USA
Am J Public Health 92:858-62. 2002..This study examined the effect of birth cohort on incidence rates of hip fracture among women and men in the Framingham Study...
Plasma B vitamins, homocysteine, and their relation with bone loss and hip fracture in elderly men and womenRobert R McLean
Institute for Aging Research, Hebrew SeniorLife, 1200 Centre Street, Boston, MA 02131, USA
J Clin Endocrinol Metab 93:2206-12. 2008..Elevated homocysteine is a strong risk factor for osteoporotic fractures among elders, yet it may be a marker for low B-vitamin status...
Second hip fracture in older men and women: the Framingham StudySarah D Berry
Department of Medicine, Beth Israel Deaconess Medical Center, Boston, MA, USA
Arch Intern Med 167:1971-6. 2007..Older persons with hip fractures remain at increased risk of subsequent hip fractures. However, little is known about the frequency and characteristics of persons who sustain a second hip fracture...
Homocysteine as a predictive factor for hip fracture in older personsRobert R McLean
Hebrew Rehabilitation Center for Aged Research and Training Institute, Boston, USA
N Engl J Med 350:2042-9. 2004..We examined the association between the total homocysteine concentration and the risk of hip fracture in men and women enrolled in the Framingham Study...
Metacarpal cortical area and risk of coronary heart disease: the Framingham StudyElizabeth J Samelson
Research and Training Institute, Hebrew Rehabilitation Center for Aged, 1200 Center Street, Boston, MA 02131, USA
Am J Epidemiol 159:589-95. 2004..53, 1.00; p(trend) = 0.03). In contrast, no association was present in men (highest vs. lowest quartile of metacarpal cortical area: hazard ratio = 1.14, 95% confidence interval: 0.84, 1.56; p(trend) = 0.55)...
Long-term effects of serum cholesterol on bone mineral density in women and men: the Framingham Osteoporosis StudyElizabeth J Samelson
Research and Training Institute, Hebrew Rehabilitation Center for Aged, Boston, MA 02131, USA
Bone 34:557-61. 2004..73, 0.72, 0.72, 0.70 g/cm2, lowest to highest quartile, P for trend=0.02. Cholesterol levels in women and men from young adulthood to middle age years do not appear to have long-term clinical implications for osteoporosis later in life...
Vertebral deformity, back symptoms, and functional limitations among older women: the Framingham StudySusan L Edmond
University of Medicine and Dentistry New Jersey, SHRP PT, 65 Bergen Street, Newark, NJ 07101 1709, USA
Osteoporos Int 16:1086-95. 2005..Efforts to prevent and treat back pain, independent of vertebral deformity status, might help to reduce functional limitations in older women...
Prevalent vertebral fracture and the risk of incident vertebral fractureElizabeth J Samelson
JAMA 299:1666; author reply 1666-7. 2008
