Affiliation: Harvard University
- Elderly patients with dementia-related symptoms of severe agitation and aggression: consensus statement on treatment options, clinical trials methodology, and policyCarl Salzman
Department of Psychiatry, Harvard Medical School, Boston, Mass 02115, USA
J Clin Psychiatry 69:889-98. 2008..In 2005, the FDA issued a black box warning regarding increased risk of mortality associated with the use of atypical antipsychotic drugs in this patient population...
- Association between prior authorization for medications and health service use by Medicaid patients with bipolar disorderChristine Y Lu
Department of Population Medicine, Harvard Medical School, 133 Brookline Ave, 6th Floor, Boston, MA 02215, USA
Psychiatr Serv 62:186-93. 2011..This study examined the association between a Medicaid prior-authorization policy for second-generation antipsychotic and anticonvulsant agents and medication discontinuation and health service use by patients with bipolar disorder...
- The limited role of expert guidelines in teaching psychopharmacologyCarl Salzman
Hravard Medical School, Boston, Massachusetts, USA
Acad Psychiatry 29:176-9. 2005..To consider the limited usefulness of expert guidelines for teaching psychopharmacology...
- Late-life anxiety disordersCarl Salzman
Massachusetts Mental Health Center, Boston, Massachusetts, 02115, USA
Psychopharmacol Bull 38:25-30. 2004..Until studies are completed, treatment of late-life anxiety will continue to be guided by extrapolating data from the general adult population. Psychopharmacology Bulletin. 2004;38(Suppl 1): 25-30...
- A 60-year-old woman who has felt sad for much of her lifeCarl Salzman
Harvard Medical School, Boston, USA
JAMA 295:318-23. 2006
- New uses for lithium and anticonvulsantsCarl Salzman
Department of Psychiatry, Harvard Medical School, Boston, MA, USA
Harv Rev Psychiatry 11:230-44. 2003..The potential usefulness of these medications for 21 other conditions has been reported in the literature, primarily from small case series or open-label, uncontrolled trials...
- Lack of relationship between long-term use of benzodiazepines and escalation to high dosagesStephen B Soumerai
Department of Ambulatory Care and Prevention, Harvard Medical School, Boston, MA, USA
Psychiatr Serv 54:1006-11. 2003..The objective of this study was to determine whether long-term benzodiazepine use is associated with dose escalation...
- A retrospective data analysis of the impact of the New York triplicate prescription program on benzodiazepine use in medicaid patients with chronic psychiatric and neurologic disordersLinda Simoni-Wastila
Department of Ambulatory Care and Prevention, Harvard Medical School and Harvard Pilgrim Health Care, Boston, Massachusetts, USA
Clin Ther 26:322-36. 2004..In January 1989, New York implemented regulations requiring physicians to order benzodiazepines using state-monitored triplicate prescription forms...
- A controlled study of the effects of state surveillance on indicators of problematic and non-problematic benzodiazepine use in a Medicaid populationDennis Ross-Degnan
Harvard Medical School and Harvard Pilgrim Health Care, Boston, MA 02215, USA
Int J Psychiatry Med 34:103-23. 2004..CONCLUSIONS: State-mandated physician surveillance dramatically reduces BZ use with limited substitution of alternative drugs, lowers rates of possible abuse, but may severely limit non-problematic BZ use...
- Atypical antipsychotics in elderly patients with dementia or schizophrenia: review of recent literatureDilip V Jeste
Department of Psychiatry, University of California San Diego, and Veterans Affairs San Diego Healthcare System 116A 1, 3350 La Jolla Village Drive, San Diego, CA 92161, USA
Harv Rev Psychiatry 13:340-51. 2005..Clinical judgment, caution, and consent should be the watchwords in this area of psychopharmacology...
- Racial disparities in access after regulatory surveillance of benzodiazepinesSallie-Anne Pearson
Department of Ambulatory Care and Prevention, Harvard Medical School and Harvard Pilgrim Health Care, Boston, Massachusetts 02215, USA
Arch Intern Med 166:572-9. 2006..The policy may have resulted in an unintended decrease in nonproblematic use that disproportionately affects black populations...
- Pharmacologic treatment of disturbed sleep in the elderlyCarl Salzman
Harvard Medical School, Boston, MA, USA carl
Harv Rev Psychiatry 16:271-8. 2008..Hypnotic drugs should be used in conjunction with nonmedication treatments, including appropriate sleep hygiene practice, and treatment of other medical or psychiatric causes of disturbed sleep...
- Sleep in the elderly: normal variations and common sleep disordersSonia Ancoli-Israel
Department of Psychiatry, University of California San Diego, La Jolla, CA 92093 0603, USA
Harv Rev Psychiatry 16:279-86. 2008..Nonpharmacological treatment techniques are discussed; pharmacological treatments are discussed in a companion article...
- Teaching psychopharmacology: what works and what doesn'tSidney Zisook
Department of Psychiatry, University of California, San Diego, La Jolla, CA 92093, USA
J Clin Psychopharmacol 28:96-100. 2008....
- Atypical uses of atypical antipsychoticsNora Selengut Brooke
Department of Psychiatry, Harvard Medical School, Beth Israel Deaconess Medical Center, Boston, MA, USA
Harv Rev Psychiatry 13:317-39. 2005..It has not yet been determined whether the usefulness of atypical antipsychotics for nonpsychotic disorders outweighs their potential to cause serious side effects...
- Drug and ECT treatment of depression in the elderly, 1996-2001: a literature reviewCarl Salzman
Department of Psychiatry, Harvard Medical School, Massachusetts Mental Health Center, Boston 02115, USA
Biol Psychiatry 52:265-84. 2002..Research studies of depressed elderly increased markedly since 1995 compared with all previous years although more studies are still necessary...
- A randomized, placebo-controlled trial of paroxetine in nursing home residents with non-major depressionAdam B Burrows
Geriatrics Section, Boston University School of Medicine, 74 Fenwood Road, Boston, MA 02115, USA
Depress Anxiety 15:102-10. 2002..The study also illustrates the discordance between patient and caregiver ratings, and the difficulties in studying very elderly patients with mood disorders...
- Are benzodiazepines still the medication of choice for patients with panic disorder with or without agoraphobia?Steven E Bruce
Brown University, Providence, RI 02906, USA
Am J Psychiatry 160:1432-8. 2003..The authors examined how the use of psychotropic drugs has shifted over the course of 10 years to determine if prescribing patterns have changed to reflect these revised treatment guidelines...
- Update: new uses for lithium and anticonvulsantsJennifer M Rosenberg
Front Range Clinical Research, Wheat Ridge, CO, USA
CNS Spectr 12:831-41. 2007..Although anticonvulsant and lithium augmentation for schizophrenia is common in practice and has been studied in double-blind, randomized, controlled trials, the sum of the evidence has been inconclusive...
- Are there predictors of outcome in depressed elderly nursing home residents during treatment with mirtazapine orally disintegrating tablets?J Craig Nelson
University California San Francisco, San Francisco, CA, USA
Int J Geriatr Psychiatry 22:999-1003. 2007..Treatment studies of depression in residential care are limited. Reports of predictors of response are rare. In the largest nursing home prospective antidepressant trial reported, we examined predictors of response...
- Open-label study of mirtazapine orally disintegrating tablets in depressed patients in the nursing homeSteven P Roose
Columbia University College of Physicians and Surgeons, Columbia University, New York, New York 10032, USA
Curr Med Res Opin 19:737-46. 2003..To evaluate the efficacy and tolerability of mirtazapine orally disintegrating tablets in depressed, elderly nursing home residents, under naturalistic study conditions...
- Depression in the elderlyWilliam M McDonald
Fuqua Center for Late-Life Depression, Emory University, Atlanta, USA
Psychopharmacol Bull 36:112-22. 2002..Treatment should also take into account the likelihood of achieving and maintaining remission of symptoms in order to restore the patient to a baseline level of functioning appropriate for their age...
- Schizophrenia in late lifeLarry E Tune
Department of Psychiatry and Behavioral Sciences, Emory University School of Medicine, Atlanta, GA, USA
Psychiatr Clin North Am 26:103-13. 2003..Within these two groups, treatment response, effective dose ranges, and sensitivity to side effects can be scrutinized more carefully...
- Depression and Bipolar Support Alliance consensus statement on the unmet needs in diagnosis and treatment of mood disorders in late lifeDennis S Charney
National Institute of Mental Health, National Institutes of Health, Bethesda, MD, USA
Arch Gen Psychiatry 60:664-72. 2003....
- Schizophrenia symptoms remain stable during decreases from 2 antipsychotics to aripiprazoleCarl Salzman
J Clin Psychiatry 68:970. 2007
- Improving the pedagogy associated with the teaching of psychopharmacologyIra D Glick
Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, CA 94305, USA
Acad Psychiatry 31:211-7. 2007..The focus was on whether "improving the teaching-learning process" in psychiatric residency programs could improve clinical practice...
- ACNP White Paper: update on use of antipsychotic drugs in elderly persons with dementiaDilip V Jeste
Department of Psychiatry and Neurosciences, University of California, San Diego, CA 92161, USA
Neuropsychopharmacology 33:957-70. 2008..The role of shared decision making and caution in using pharmacotherapy for these patients is stressed...