Research Topics
Species | Sharon K SagivSummaryAffiliation: Harvard University Country: USA Publications
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Publications
Prenatal organochlorine exposure and measures of behavior in infancy using the Neonatal Behavioral Assessment Scale (NBAS)Sharon K Sagiv
Department of Environmental Health, Channing Laboratory, Harvard School of Public Health, Boston, MA 02115, USA
Environ Health Perspect 116:666-73. 2008..Previous literature suggests an association between organochlorines and behavioral measures in childhood, including inattention...
Active and passive cigarette smoke and breast cancer survivalSharon K Sagiv
Department of Epidemiology, School of Public Health, University of North Carolina, Chapel Hill, NC, USA
Ann Epidemiol 17:385-93. 2007..The association between active and passive cigarette smoking before breast cancer diagnosis and survival was investigated among a cohort of invasive breast cancer cases (n = 1273) participating in a population-based case-control study...
Organochlorine exposures during pregnancy and infant size at birthSharon K Sagiv
Department of Environmental Health, Harvard School of Public Health, Boston, Massachusetts, USA
Epidemiology 18:120-9. 2007..Organochlorines, including polychlorinated biphenyls (PCBs) and pesticides, are environmentally persistent contaminants that concentrate in the food chain as well in human adipose tissue and readily cross the placenta...
Polycyclic aromatic hydrocarbon-DNA adducts and survival among women with breast cancerSharon K Sagiv
Department of Epidemiology, School of Public Health, University of North Carolina, Chapel Hill, NC, USA
Environ Res 109:287-91. 2009..Results from this large population-based study do not provide strong support for an association between detectable PAH-DNA adducts and survival among women with breast cancer, except perhaps among those receiving radiation treatment...
Prenatal organochlorine exposure and behaviors associated with attention deficit hyperactivity disorder in school-aged childrenSharon K Sagiv
Department of Environmental Health, Harvard School of Public Health, Boston, MA 02115, USA
Am J Epidemiol 171:593-601. 2010..76, 95% confidence interval: 1.06, 2.92) and a similar relation for p,p'-DDE. These results support an association between low-level prenatal organochlorine exposure and ADHD-like behaviors in childhood...
A time-series analysis of air pollution and preterm birth in Pennsylvania, 1997-2001Sharon K Sagiv
Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA
Environ Health Perspect 113:602-6. 2005..The results from this time-series analysis, which provides evidence of an increase in preterm birth risk with exposure to PM10 and SO2, are consistent with prior investigations of spatial contrasts...
Polycyclic aromatic hydrocarbon-DNA adducts and breast cancer: a pooled analysisMarilie D Gammon
Department of Epidemiology, University of North Carolina School of Public Health, Chapel Hill, North Carolina 27599 7435, USA
Arch Environ Health 59:640-9. 2004..These data provide only modest support for an association between PAH-DNA adducts and breast cancer development...
Polymorphisms in nucleotide excision repair genes, polycyclic aromatic hydrocarbon-DNA adducts, and breast cancer riskKatherine D Crew
Department of Epidemiology, Mailman School of Public Health, Columbia University, 161 Fort Washington Avenue, New York, NY 10032, USA
Cancer Epidemiol Biomarkers Prev 16:2033-41. 2007..Overall, this study suggests that the risk of breast cancer may be elevated among women with polymorphisms in NER pathway genes and detectable PAH-DNA adducts...
Genetic variation of TP53, polycyclic aromatic hydrocarbon-related exposures, and breast cancer risk among women on Long Island, New YorkMia M Gaudet
Department of Epidemiology, School of Public Health, University of North Carolina, Chapel Hill, NC, USA
Breast Cancer Res Treat 108:93-9. 2008..p53 participates in cell cycle control, programmed cell death/apoptosis, and DNA repair, all pathways involved in carcinogenesis. TP53 variants may influence p53 function...
Neuropsychological measures of attention and impulse control among 8-year-old children exposed prenatally to organochlorinesSharon K Sagiv
Department of Environmental Health, Boston University School of Public Health, Boston, Massachusetts 02118, USA
Environ Health Perspect 120:904-9. 2012....
Residential environmental exposures and other characteristics associated with detectable PAH-DNA adducts in peripheral mononuclear cells in a population-based sample of adult femalesSumitra Shantakumar
Department of Epidemiology, CB 7435 McGavran Greenberg Hall, University of North Carolina School of Public Health, Chapel Hill, North Carolina 27599 7435, USA
J Expo Anal Environ Epidemiol 15:482-90. 2005..These data suggest that PAH-DNA adducts detected in a population-based sample of adult women with ambient exposure levels reflect some key residential PAH exposure sources assessed in this study, such as cigarette smoking...
PAH-DNA adducts, cigarette smoking, GST polymorphisms, and breast cancer riskKathleen M McCarty
Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA
Environ Health Perspect 117:552-8. 2009..Few breast cancer studies have investigated the joint effects of multiple GSTs and a PAH biomarker...
Polymorphism in the DNA repair gene XPD, polycyclic aromatic hydrocarbon-DNA adducts, cigarette smoking, and breast cancer riskMary Beth Terry
Department of Epidemiology, Mailman School of Public Health, Columbia University, PH 18 102, 600 West 168th Street, New York, NY 10032, USA
Cancer Epidemiol Biomarkers Prev 13:2053-8. 2004..Overall, this study suggests that those individuals with this polymorphism in the XPD gene may face an increased risk of breast cancer from PAH-DNA adducts and cigarette smoking...
Prenatal exposure to mercury and fish consumption during pregnancy and attention-deficit/hyperactivity disorder-related behavior in childrenSharon K Sagiv
Department of Environmental Health, Boston University School of Public Health, Boston, Massachusetts 02118, USA
Arch Pediatr Adolesc Med 166:1123-31. 2012..To investigate the association of prenatal mercury exposure and fish intake with attention-deficit/hyperactivity disorder (ADHD)-related behavior...
Plasma organochlorine levels and risk of non-Hodgkin lymphoma in the Nurses' Health StudyFrancine Laden
Channing Laboratory, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, 181 Longwood Avenue, Boston, MA 02115, USA
Cancer Epidemiol Biomarkers Prev 19:1381-4. 2010..These results do not support the hypothesis of a positive association between PCB exposure and development of NHL...
Polychlorinated biphenyls, organochlorine pesticides and neurodevelopmentSusan A Korrick
Channing Laboratory, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA
Curr Opin Pediatr 20:198-204. 2008..The review will describe current understanding of the potential neurodevelopmental consequences of low-level exposures to these contaminants...
Consumption of sweet foods and breast cancer risk: a case-control study of women on Long Island, New YorkPatrick T Bradshaw
Department of Epidemiology, CB 7435 McGavran Greenberg Hall, School of Public Health, University of North Carolina, Chapel Hill, NC 27599 7435, USA
Cancer Causes Control 20:1509-15. 2009..These results are consistent with other studies that implicate insulin-related factors in breast carcinogenesis...
Associations between polycyclic aromatic hydrocarbon-related exposures and p53 mutations in breast tumorsIrina Mordukhovich
Department of Epidemiology, University of North Carolina, Chapel Hill, North Carolina 27599 7435, USA
Environ Health Perspect 118:511-8. 2010..Objectives: We hypothesized that associations of PAH-related exposures with breast cancer would differ according to tumor p53 mutation status, effect, type, and number...
Pre- and postnatal risk factors for ADHD in a nonclinical pediatric populationSharon K Sagiv
Department of Environmental Health, Boston University School of Public Health, MA 02118, USA
J Atten Disord 17:47-57. 2013..The authors characterized pre- and postnatal risk factors for ADHD among a population-based sample of 8-year-old children followed since birth (N = 604)...
MGMT genotype modulates the associations between cigarette smoking, dietary antioxidants and breast cancer riskJing Shen
Department of Environmental Health Sciences, Columbia University, New York, NY 10032, USA
Carcinogenesis 26:2131-7. 2005....
Polymorphisms in XRCC1 modify the association between polycyclic aromatic hydrocarbon-DNA adducts, cigarette smoking, dietary antioxidants, and breast cancer riskJing Shen
Department of Environmental Health Sciences, Mailman School of Public Health, Columbia University, New York, NY 10032, USA
Cancer Epidemiol Biomarkers Prev 14:336-42. 2005..Further understanding of the biological function of XRCC1 variants and their interactions with PAH-DNA adducts, antioxidants, and other genes in the pathway are needed...
Genetic polymorphisms in the apoptosis-associated genes FAS and FASL and breast cancer riskKatherine D Crew
Department of Medicine and the Herbert Irving Comprehensive Cancer Center, Columbia University, 161 Fort Washington Avenue, 10 1072, New York, NY 10032, USA
Carcinogenesis 28:2548-51. 2007..Overall, this study suggests that the risk of breast cancer may be elevated among women with polymorphisms in the FAS gene and detectable PAH-DNA adducts...
OGG1 polymorphisms and breast cancer riskPavel Rossner
Department of Environmental Health Sciences, Mailman School of Public Health, Columbia University, New York, New York, USA
Cancer Epidemiol Biomarkers Prev 15:811-5. 2006..In addition, data on functionality of these polymorphisms are crucial to understand if these modest differences are important...
IGHMBP2 Thr671Ala polymorphism might be a modifier for the effects of cigarette smoking and PAH-DNA adducts to breast cancer riskJing Shen
Department of Environmental Health Sciences, Mailman School of Public Health, Columbia University, New York, NY, USA
Breast Cancer Res Treat 99:1-7. 2006..Additional studies focused on the biological function of the variant-G allele and interactions with other genetic polymorphisms are necessary to confirm our findings...
