Research Topics
Genomes and Genes | N RosenthalSummaryAffiliation: Harvard University Country: USA Publications
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Publications
From the bottom of the heart: anteroposterior decisions in cardiac muscle differentiationN Rosenthal
Cardiovascular Research Center, Massachusetts General Hospital, Charlestown, MA 02129, USA
Curr Opin Cell Biol 12:742-6. 2000..In the past year, a wealth of information on these signals has emerged, elucidating the general pathways controlling body axes in the context of the developing heart...- Sequential programs of retinoic acid synthesis in the myocardial and epicardial layers of the developing avian heartJ Xavier-Neto
Cardiovascular Research Center, Massachusetts General Hospital, Charlestown, Massachusetts, 02129, USA
Dev Biol 219:129-41. 2000.... - A retinoic acid-inducible transgenic marker of sino-atrial development in the mouse heartJ Xavier-Neto
Cardiovascular Research Center, Massachusetts General Hospital, Charlestown, MA 02129, USA
Development 126:2677-87. 1999..It also suggests that atrial-specific gene expression is controlled by localized synthesis of RA, and that exclusion of RA from ventricular precursors is essential for correct specification of the ventricles... - Localized Igf-1 transgene expression sustains hypertrophy and regeneration in senescent skeletal muscleA Musaro
Cardiovascular Research Center, Massachusetts General Hospital East, Charlestown, Massachusetts, USA
Nat Genet 27:195-200. 2001..The preservation of muscle architecture and age-independent regenerative capacity through localized mIgf-1 transgene expression suggests clinical strategies for the treatment of age or disease-related muscle frailty... - Dynamic patterns of retinoic acid synthesis and response in the developing mammalian heartJ B Moss
Cardiovascular Research Center, Massachusetts General Hospital, Charlestown 02129, USA
Dev Biol 199:55-71. 1998..These observations support a model in which the influence of endogenous RA on heart development depends upon localized presentation of the ligand, with only limited diffusion from the source of its synthesis... - Regulation of a muscle-specific transgene by persistent expression of Hox genes in postnatal murine limb muscleL Houghton
Cardiovascular Research Center, Massachusetts General Hospital East, Charlestown 02129, USA
Dev Dyn 216:385-97. 1999..These results indicate that members of the HoxA and C clusters may, in combination, mediate various aspects of differentiation and patterning in adult musculature... - Green fluorescent protein marks skeletal muscle in murine cell lines and zebrafishJ B Moss
Cardiovascular Research Center, Massachusetts General Hospital East, Charlestown 02129, USA
Gene 173:89-98. 1996..Transgenic fish continued to express high levels of gfp in skeletal muscle at 1.5 months, demonstrating that GFP is an effective marker of muscle cells in vivo... - Developmental regulation of Zbu1, a DNA-binding member of the SWI2/SNF2 familyX Gong
Cardiovascular Research Center, Massachusetts General Hospital East, Charlestown 02129, USA
Dev Biol 183:166-82. 1997....