J T Rogers

Summary

Affiliation: Harvard University
Country: USA

Publications

  1. ncbi request reprint Translation of the alzheimer amyloid precursor protein mRNA is up-regulated by interleukin-1 through 5'-untranslated region sequences
    J T Rogers
    Division of Hematology, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA
    J Biol Chem 274:6421-31. 1999
  2. ncbi request reprint Ferritin translation by interleukin-1and interleukin-6: the role of sequences upstream of the start codons of the heavy and light subunit genes
    J T Rogers
    Division of Hematology Oncology, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02115 USA
    Blood 87:2525-37. 1996
  3. ncbi request reprint Iron-dependent regulation of the divalent metal ion transporter
    H Gunshin
    Membrane Biology Program and Renal Division, Brigham and Women s Hospital and Harvard Medical School, Harvard Institutes of Medicine, 77 Avenue Louis Pasteur, Boston, MA 02115, USA
    FEBS Lett 509:309-16. 2001
  4. pmc Translational enhancement of H-ferritin mRNA by interleukin-1 beta acts through 5' leader sequences distinct from the iron responsive element
    J T Rogers
    Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02115
    Nucleic Acids Res 22:2678-86. 1994
  5. ncbi request reprint Role of the APP non-amyloidogenic signaling pathway and targeting alpha-secretase as an alternative drug target for treatment of Alzheimer's disease
    S Bandyopadhyay
    Laboratory for Neurochemistry, Department of Psychiatry Neuroscience, and Genetics, Massachusetts General Hospital, Boston, MA, USA
    Curr Med Chem 14:2848-64. 2007
  6. ncbi request reprint Role of cytokines in the gene expression of amyloid beta-protein precursor: identification of a 5'-UTR-binding nuclear factor and its implications in Alzheimer's disease
    D K Lahiri
    Department of Psychiatry, Institute of Psychiatric Research, 791 Union Drive, Indiana University School of Medicine, Indianapolis, IN 46202, USA
    J Alzheimers Dis 5:81-90. 2003
  7. ncbi request reprint The 5'-untranslated region of Parkinson's disease alpha-synuclein messengerRNA contains a predicted iron responsive element
    A L Friedlich
    Mol Psychiatry 12:222-3. 2007

Collaborators

Detail Information

Publications7

  1. ncbi request reprint Translation of the alzheimer amyloid precursor protein mRNA is up-regulated by interleukin-1 through 5'-untranslated region sequences
    J T Rogers
    Division of Hematology, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA
    J Biol Chem 274:6421-31. 1999
    ..Enhanced translation of APP mRNA provides a mechanism by which IL-1 influences the pathogenesis of AD...
  2. ncbi request reprint Ferritin translation by interleukin-1and interleukin-6: the role of sequences upstream of the start codons of the heavy and light subunit genes
    J T Rogers
    Division of Hematology Oncology, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02115 USA
    Blood 87:2525-37. 1996
    ..Transfected hybrid H-mRNA SUS/CAT mRNAs with a three nucleotide deleted version of the H-mRNA SUS displays an eightfold reduced level of translation and no longer confer IL-1beta-dependent translation...
  3. ncbi request reprint Iron-dependent regulation of the divalent metal ion transporter
    H Gunshin
    Membrane Biology Program and Renal Division, Brigham and Women s Hospital and Harvard Medical School, Harvard Institutes of Medicine, 77 Avenue Louis Pasteur, Boston, MA 02115, USA
    FEBS Lett 509:309-16. 2001
    ..We propose that regulation of DCT1/DMT1 mRNA by iron involves post-transcriptional regulation through the binding of IRP1 to the transporter's IRE, as well as other as yet unknown factors...
  4. pmc Translational enhancement of H-ferritin mRNA by interleukin-1 beta acts through 5' leader sequences distinct from the iron responsive element
    J T Rogers
    Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02115
    Nucleic Acids Res 22:2678-86. 1994
    ..Deletion of three nucleotides from this region of the 61 nt G + C rich element in the H-ferritin mRNA 5' leader eliminates Il-1 beta translational enhancement of the CAT reporter transcripts...
  5. ncbi request reprint Role of the APP non-amyloidogenic signaling pathway and targeting alpha-secretase as an alternative drug target for treatment of Alzheimer's disease
    S Bandyopadhyay
    Laboratory for Neurochemistry, Department of Psychiatry Neuroscience, and Genetics, Massachusetts General Hospital, Boston, MA, USA
    Curr Med Chem 14:2848-64. 2007
    ....
  6. ncbi request reprint Role of cytokines in the gene expression of amyloid beta-protein precursor: identification of a 5'-UTR-binding nuclear factor and its implications in Alzheimer's disease
    D K Lahiri
    Department of Psychiatry, Institute of Psychiatric Research, 791 Union Drive, Indiana University School of Medicine, Indianapolis, IN 46202, USA
    J Alzheimers Dis 5:81-90. 2003
    ..The characterization of AbetaPP regulatory elements, including the 5'-UTR, will accelerate the development of novel agents against new targets for AD...
  7. ncbi request reprint The 5'-untranslated region of Parkinson's disease alpha-synuclein messengerRNA contains a predicted iron responsive element
    A L Friedlich
    Mol Psychiatry 12:222-3. 2007