Genomes and Genes
Jennifer R Rider
Affiliation: Harvard University
- Long-term outcomes among noncuratively treated men according to prostate cancer risk category in a nationwide, population-based studyJennifer R Rider
Channing Laboratory, Department of Medicine, Brigham and Women s Hospital, Boston, MA, USA
Eur Urol 63:88-96. 2013..Limited data exist on long-term outcomes among men with prostate cancer (PCa) from population-based cohorts incorporating information on clinical risk category...
- Modification of the association between obesity and lethal prostate cancer by TMPRSS2:ERGAndreas Pettersson
Affiliations of authors Department of Epidemiology AP, AM, MF, REG, KLP, JRR, EJN, MJS, ELG, LAM and Department of Nutrition MJS, ELG, Harvard School of Public Health, Boston, MA Channing Division of Network Medicine AP, KLP, JRR, MJS, ELG, LAM and Division of Preventive Medicine HDS, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA Department of Pathology, Brigham and Women s Hospital, Boston, MA RTL, ECS, ML Center for Molecular Oncologic Pathology RTL, RF, ECS, MF, SF, NEM, ML, Department of Radiation Oncology NEM, Centre for Regenerative Medicine
J Natl Cancer Inst 105:1881-90. 2013..TMPRSS2:ERG is a hormonally regulated gene fusion present in about half of prostate tumors. We investigated whether obesity, which deregulates several hormonal pathways, interacts with TMPRSS2:ERG to impact prostate cancer outcomes...
- Gleason grade progression is uncommonKathryn L Penney
Department of Epidemiology, Harvard School of Public Health, Brigham and Women s Hospital and Harvard Medical School, Boston, MA 02115, USA
Cancer Res 73:5163-8. 2013..This has implications for the understanding of tumor progression and prognosis, and may help patients diagnosed with lower grade disease feel more comfortable choosing active surveillance...
- A single nucleotide polymorphism in inflammatory gene RNASEL predicts outcome after radiation therapy for localized prostate cancerJonathan D Schoenfeld
Harvard Radiation Oncology Program, Boston, Massachusetts, USA
Clin Cancer Res 19:1612-9. 2013..To study associations between single nucleotide polymorphisms (SNP) in Ribonuclease L (RNASEL), a gene implicated in inflammation and prostate cancer risk, and outcomes after radiation therapy...
- Seasonal variation in expression of markers in the vitamin D pathway in prostate tissueMara M Epstein
Department of Epidemiology, Harvard School of Public Health, 677 Huntington Avenue, Boston, MA 02115, USA
Cancer Causes Control 23:1359-66. 2012..As serum vitamin D levels vary by season, we sought to determine whether the expression of genes on the vitamin D pathway, assessed in prostate tumor tissue, do the same...
- Temporal trends in cause of death among Swedish and US men with prostate cancerMara M Epstein
Department of Epidemiology, Harvard School of Public Health, 677 Huntington Ave, 9th Floor, Boston, MA 02115, USA
J Natl Cancer Inst 104:1335-42. 2012..Temporal trends in specific causes of death among prostate cancer patients have not been well described...
- The TMPRSS2:ERG rearrangement, ERG expression, and prostate cancer outcomes: a cohort study and meta-analysisAndreas Pettersson
Channing Laboratory, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA, USA
Cancer Epidemiol Biomarkers Prev 21:1497-509. 2012..Whether the genomic rearrangement transmembrane protease, serine 2 (TMPRSS2):v-ets erythroblastosis virus E26 oncogene homolog (ERG) has prognostic value in prostate cancer is unclear...
- Coffee consumption and prostate cancer risk and progression in the Health Professionals Follow-up StudyKathryn M Wilson
Department of Epidemiology, Harvard School of Public Health, Boston, MA 02115, USA
J Natl Cancer Inst 103:876-84. 2011..Because of these biological activities, coffee may be associated with a reduced risk of prostate cancer...
- Common polymorphisms in the adiponectin and its receptor genes, adiponectin levels and the risk of prostate cancerPreet K Dhillon
Channing Laboratory, Brigham and Women s Hospital and Harvard Medical School Boston, MA, USA
Cancer Epidemiol Biomarkers Prev 20:2618-27. 2011..However, the role of genetic variation in the adiponectin (ADIPOQ) and receptor genes (ADIPOR1/R2) in prostate cancer is largely unknown...