Gili Regev-Yochay

Summary

Affiliation: Harvard University
Country: USA

Publications

  1. doi request reprint A nationwide surveillance of invasive pneumococcal disease in adults in Israel before an expected effect of PCV7
    Gili Regev-Yochay
    Infectious Disease Unit, Sheba Medical Center, Ramat Gan, Israel, affiliated to the Sackler School of Medicine, Tel Aviv University, Israel
    Vaccine 31:2387-94. 2013
  2. pmc Streptococcus pneumoniae carriage in the Gaza strip
    Gili Regev-Yochay
    Infectious Disease Unit, Sheba Medical Center, Tel Hashomer affiliated to the Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel
    PLoS ONE 7:e35061. 2012
  3. pmc The pneumococcal pilus predicts the absence of Staphylococcus aureus co-colonization in pneumococcal carriers
    Gili Regev-Yochay
    Department of Medicine, Division of Infectious Diseases, Children s Hospital, Harvard Medical School, Boston, Massachusetts, USA
    Clin Infect Dis 48:760-3. 2009
  4. doi request reprint Parental Staphylococcus aureus carriage is associated with staphylococcal carriage in young children
    Gili Regev-Yochay
    Infectious Diseases Unit, Sheba Medical Center and Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel
    Pediatr Infect Dis J 28:960-5. 2009
  5. pmc In vitro bactericidal activity of Streptococcus pneumoniae and bactericidal susceptibility of Staphylococcus aureus strains isolated from cocolonized versus noncocolonized children
    Gili Regev-Yochay
    Department of Epidemiology and Department of Immunology and Infectious Diseases, Harvard School of Public Health, Boston, MA 02115, USA
    J Clin Microbiol 46:747-9. 2008
  6. pmc SpxB is a suicide gene of Streptococcus pneumoniae and confers a selective advantage in an in vivo competitive colonization model
    Gili Regev-Yochay
    Department of Epidemiology and Department of Immunology and Infectious Diseases, Harvard School of Public Health, 677 Huntington Ave, Boston, MA 02115, USA
    J Bacteriol 189:6532-9. 2007
  7. pmc Re-emergence of the type 1 pilus among Streptococcus pneumoniae isolates in Massachusetts, USA
    Gili Regev-Yochay
    Division of Infectious Diseases, Department of Medicine, Children s Hospital Boston, Harvard Medical School, Boston, MA, USA
    Vaccine 28:4842-6. 2010
  8. ncbi request reprint Prevalence and genetic relatedness of community-acquired methicillin-resistant Staphylococcus aureus in Israel
    G Regev-Yochay
    Infectious Diseases Unit, Sheba Medical Center, Ramat Gan, Israel
    Eur J Clin Microbiol Infect Dis 25:719-22. 2006
  9. pmc Interference between Streptococcus pneumoniae and Staphylococcus aureus: In vitro hydrogen peroxide-mediated killing by Streptococcus pneumoniae
    Gili Regev-Yochay
    Department of Epidemiology, Harvard School of Public Health, 677 Huntington Ave, Boston, MA 02115, USA
    J Bacteriol 188:4996-5001. 2006
  10. doi request reprint Reduction in antibiotic use following a cluster randomized controlled multifaceted intervention: the Israeli judicious antibiotic prescription study
    Gili Regev-Yochay
    Infectious Disease Unit, Sheba Medical Center, Ramat Gan, Israel
    Clin Infect Dis 53:33-41. 2011

Detail Information

Publications24

  1. doi request reprint A nationwide surveillance of invasive pneumococcal disease in adults in Israel before an expected effect of PCV7
    Gili Regev-Yochay
    Infectious Disease Unit, Sheba Medical Center, Ramat Gan, Israel, affiliated to the Sackler School of Medicine, Tel Aviv University, Israel
    Vaccine 31:2387-94. 2013
    ..9% and 67.9% of isolates in mortality cases respectively. This nationwide active surveillance provides the baseline incidence, mortality rates and risk group distributions of IPD in adults before expected PCV effect...
  2. pmc Streptococcus pneumoniae carriage in the Gaza strip
    Gili Regev-Yochay
    Infectious Disease Unit, Sheba Medical Center, Tel Hashomer affiliated to the Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel
    PLoS ONE 7:e35061. 2012
    ..We report the epidemiology of S. pneumoniae carriage in a developing region, the Gaza strip, and evaluate the theoretical coverage of carriage strains by pneumococcal conjugate vaccines (PCVs)...
  3. pmc The pneumococcal pilus predicts the absence of Staphylococcus aureus co-colonization in pneumococcal carriers
    Gili Regev-Yochay
    Department of Medicine, Division of Infectious Diseases, Children s Hospital, Harvard Medical School, Boston, Massachusetts, USA
    Clin Infect Dis 48:760-3. 2009
    ..aureus were significantly lower for individuals carrying a piliated versus a nonpiliated S. pneumoniae strain, suggesting the pilus may be a determinant of the negative association...
  4. doi request reprint Parental Staphylococcus aureus carriage is associated with staphylococcal carriage in young children
    Gili Regev-Yochay
    Infectious Diseases Unit, Sheba Medical Center and Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel
    Pediatr Infect Dis J 28:960-5. 2009
    ..Our previous study suggested that S. aureus carriage in children is associated with parental carriage. Here we wished to distinguish the different components that play a role in the risk to a child of a S. aureus-carrying parent...
  5. pmc In vitro bactericidal activity of Streptococcus pneumoniae and bactericidal susceptibility of Staphylococcus aureus strains isolated from cocolonized versus noncocolonized children
    Gili Regev-Yochay
    Department of Epidemiology and Department of Immunology and Infectious Diseases, Harvard School of Public Health, Boston, MA 02115, USA
    J Clin Microbiol 46:747-9. 2008
    ..Thus, in vitro killing is not the major determinant of the pattern of cocolonization...
  6. pmc SpxB is a suicide gene of Streptococcus pneumoniae and confers a selective advantage in an in vivo competitive colonization model
    Gili Regev-Yochay
    Department of Epidemiology and Department of Immunology and Infectious Diseases, Harvard School of Public Health, 677 Huntington Ave, Boston, MA 02115, USA
    J Bacteriol 189:6532-9. 2007
    ..We conclude that a suicide gene of pneumococcus is spxB, which induces an apoptosis-like death in pneumococci and confers a selective advantage in nasopharyngeal cocolonization...
  7. pmc Re-emergence of the type 1 pilus among Streptococcus pneumoniae isolates in Massachusetts, USA
    Gili Regev-Yochay
    Division of Infectious Diseases, Department of Medicine, Children s Hospital Boston, Harvard Medical School, Boston, MA, USA
    Vaccine 28:4842-6. 2010
    ..These emerging piliated non-VT strains are mostly novel clones, with some exceptions. The rise in pilus type 1 frequency across multiple distinct genetic backgrounds suggests that the pilus may confer an intrinsic advantage...
  8. ncbi request reprint Prevalence and genetic relatedness of community-acquired methicillin-resistant Staphylococcus aureus in Israel
    G Regev-Yochay
    Infectious Diseases Unit, Sheba Medical Center, Ramat Gan, Israel
    Eur J Clin Microbiol Infect Dis 25:719-22. 2006
    ..Isolates were negative for pvl and were classified as ST-45-MRSA. Although CA-MRSA is still rare in Israel, the genetic relatedness of the strains found in this study to a successful MSSA clone warrants close follow up...
  9. pmc Interference between Streptococcus pneumoniae and Staphylococcus aureus: In vitro hydrogen peroxide-mediated killing by Streptococcus pneumoniae
    Gili Regev-Yochay
    Department of Epidemiology, Harvard School of Public Health, 677 Huntington Ave, Boston, MA 02115, USA
    J Bacteriol 188:4996-5001. 2006
    ..These results provide a possible mechanistic explanation for the interspecies interference observed in epidemiologic studies...
  10. doi request reprint Reduction in antibiotic use following a cluster randomized controlled multifaceted intervention: the Israeli judicious antibiotic prescription study
    Gili Regev-Yochay
    Infectious Disease Unit, Sheba Medical Center, Ramat Gan, Israel
    Clin Infect Dis 53:33-41. 2011
    ....
  11. pmc Methicillin-resistant Staphylococcus aureus in neonatal intensive care unit
    Gili Regev-Yochay
    Infectious Diseases Unit, Sheba Medical Center, Tel Hashomer, Ramat Gan, 52621 Israel
    Emerg Infect Dis 11:453-6. 2005
    ..Fifteen infected neonates were identified, 2 of whom died. This outbreak illustrates how a rare community pathogen can rapidly spread through nosocomial transmission...
  12. ncbi request reprint Independent risk factors for carriage of penicillin-non-susceptible Streptococcus pneumoniae
    Gili Regev-Yochay
    Infectious Disease Unit, Sheba Medical Center, Tel Hashomer, Ramat Gan, Israel
    Scand J Infect Dis 35:219-22. 2003
    ..24, 95% CI 1.64-3.05). Young children, who attended DCC and received 1 antibiotic course (9% of the population) had a risk 12.9 times higher than children without these features...
  13. ncbi request reprint Nasopharyngeal carriage of Streptococcus pneumoniae by adults and children in community and family settings
    Gili Regev-Yochay
    Infectious Disease Unit, Sheba Medical Center, Tel Hashomer, Israel
    Clin Infect Dis 38:632-9. 2004
    ..In a subanalysis of 151 pairs of children and their parents and of 32 pairs of siblings, intrafamilial transmission of S. pneumoniae could not be demonstrated...
  14. ncbi request reprint Comparison of community-acquired methicillin-resistant Staphylococcus aureus bacteremia to other staphylococcal species in a neonatal intensive care unit
    Jacob Kuint
    Neonatal Department, The Edmond and Lili Safra Children s Hospital, Sheba Medical Center, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel
    Eur J Pediatr 166:319-25. 2007
    ..One possible explanation for this observation is that the CA-MRSA outbreak strain did not contain the pvl-gene, which has been suggested to be a significant virulence factor...
  15. ncbi request reprint Association between carriage of Streptococcus pneumoniae and Staphylococcus aureus in Children
    Gili Regev-Yochay
    Sheba Medical Center, Tel Hashomer, Israel
    JAMA 292:716-20. 2004
    ..Of particular significance may be an interaction between Streptococcus pneumoniae and Staphylococcus aureus, in view of the recent emergence of community-acquired methicillin-resistant S aureus...
  16. doi request reprint Transmission of Staphylococcus aureus from mothers to newborns
    Eyal Leshem
    Infectious Diseases Unit, The Chaim Sheba Medical Center, Tel Hashomer and the Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel
    Pediatr Infect Dis J 31:360-3. 2012
    ..The study objective was to define the risk factors and the route of Staphylococcus aureus transmission between mother and newborn...
  17. pmc A typical hospital-acquired methicillin-resistant Staphylococcus aureus clone is widespread in the community in the Gaza strip
    Asaf Biber
    Infectious Disease Unit, Sheba Medical Center, affiliated to the Sackler School of Medicine, Tel Aviv University, Ramat Gan, Israel
    PLoS ONE 7:e42864. 2012
    ..The rapid spread in the community may be due to population determinants or due to yet unknown advantageous features of this particular strain...
  18. doi request reprint Epidemiologic evidence for serotype-specific acquired immunity to pneumococcal carriage
    Daniel M Weinberger
    Department of Immunology and Infectious Diseases, Harvard School of Public Health, Boston, Massachusetts 02115, USA
    J Infect Dis 197:1511-8. 2008
    ..We found no evidence of specific protection for type 6B, group 15, or type 19F. Our findings imply that at least some serotypes generate anti-capsular antibodies that can reduce the risk of carriage in unimmunized toddlers...
  19. doi request reprint Changing parents' opinions regarding antibiotic use in primary care
    Yasmin Maor
    Infectious Disease Unit, Sheba Medical Center, Tel Hashomer 52621, Israel
    Eur J Pediatr 170:359-64. 2011
    ..Improving parents' knowledge regarding antibiotics can reduce parents' wish for antibiotic treatment...
  20. doi request reprint Potential role of active surveillance in the control of a hospital-wide outbreak of carbapenem-resistant Klebsiella pneumoniae infection
    Debby Ben-David
    Infectious Diseases Unit, Sheba Medical Center, Tel Hashomer, Israel
    Infect Control Hosp Epidemiol 31:620-6. 2010
    ..The recent emergence of carbapenem resistance among Enterobacteriaceae is a major threat for hospitalized patients, and effective strategies are needed...
  21. pmc Is methicillin-resistant Staphylococcus aureus replacing methicillin-susceptible S. aureus?
    Elizabeth Mostofsky
    Department of Epidemiology, Harvard School of Public Health, Boston, MA, USA
    J Antimicrob Chemother 66:2199-214. 2011
    ..So far, evidence indicates that MSSA still accounts for many infections. Therefore, eradication of MRSA alone is not sufficient to address the public health burden of S. aureus...
  22. doi request reprint Initial Effects of the National PCV7 Childhood Immunization Program on Adult Invasive Pneumococcal Disease in Israel
    Gili Regev-Yochay
    Infectious Disease Unit, Sheba Medical Center, Ramat Gan, Israel
    PLoS ONE 9:e88406. 2014
    ..Here we report data on adult invasive pneumococcal disease (IPD), two years post PCV7 implementation and before an expected effect of PCV13...
  23. ncbi request reprint Resistant organisms and otitis media
    Ron Dagan
    Pediatr Infect Dis J 24:849; author reply 849-51. 2005
  24. ncbi request reprint Does pneumococcal conjugate vaccine influence Staphylococcus aureus carriage in children?
    Gili Regev-Yochay
    Clin Infect Dis 47:289-91; author reply 291-2. 2008