Eva Maria Ratai

Summary

Affiliation: Harvard University
Country: USA

Publications

  1. pmc Proton MR spectroscopic imaging of rhesus macaque brain in vivo at 7T
    Oded Gonen
    Department of Radiology, New York University School of Medicine, New York, New York 10016, USA
    Magn Reson Med 59:692-9. 2008
  2. pmc Metabolic markers of neuronal injury correlate with SIV CNS disease severity and inoculum in the macaque model of neuroAIDS
    Margaret R Lentz
    Massachusetts General Hospital, Department of Neuroradiology, Boston, Massachusetts 02114 2696, USA
    Magn Reson Med 59:475-84. 2008
  3. pmc Factor analysis reveals differences in brain metabolism in macaques with SIV/AIDS and those with SIV-induced encephalitis
    Margaret R Lentz
    Department of Neuroradiology A A Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Charlestown, MA 02129, USA
    NMR Biomed 21:878-87. 2008
  4. pmc Magnetic resonance spectroscopy as an early indicator of response to anti-angiogenic therapy in patients with recurrent glioblastoma: RTOG 0625/ACRIN 6677
    Eva Maria Ratai
    A A Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Department of Radiology, Neuroradiology Division, Harvard Medical School, Building 149, 13th Street, Room 2301, Charlestown, MA 02129, USA
    Neuro Oncol 15:936-44. 2013
  5. pmc A prospective longitudinal in vivo 1H MR spectroscopy study of the SIV/macaque model of neuroAIDS
    Robert A Fuller
    Massachusetts General Hospital NMR Center and Neuroradiology Division, Harvard Medical School, Charlestown, MA, USA
    BMC Neurosci 5:10. 2004
  6. pmc Proton magnetic resonance spectroscopy reveals neuroprotection by oral minocycline in a nonhuman primate model of accelerated NeuroAIDS
    Eva Maria Ratai
    AA Martinos Center for Biomedical Imaging and Neuroradiology Division, Massachusetts General Hospital, Charlestown, Massachusetts, United States of America
    PLoS ONE 5:e10523. 2010
  7. pmc Automatic repositioning of MRSI voxels in longitudinal studies: impact on reproducibility of metabolite concentration measurements
    Eva Maria Ratai
    Massachusetts General Hospital, A A Martinos Center for Biomedical Imaging, Department of Radiology and Neuroradiology Division, Charlestown, Massachusetts 02129, USA
    J Magn Reson Imaging 27:1188-93. 2008
  8. pmc In vivo proton magnetic resonance spectroscopy reveals region specific metabolic responses to SIV infection in the macaque brain
    Eva Maria Ratai
    Neuroradiology Division, Department of Radiology and A A Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Charlestown, Massachusetts 02129, USA
    BMC Neurosci 10:63. 2009
  9. pmc Brain metabolites B1-corrected proton T1 mapping in the rhesus macaque at 3 T
    Songtao Liu
    Department of Radiology, New York University School of Medicine, New York, New York, USA
    Magn Reson Med 63:865-71. 2010
  10. pmc Brain creatine elevation and N-Acetylaspartate reduction indicates neuronal dysfunction in the setting of enhanced glial energy metabolism in a macaque model of neuroAIDS
    Eva Maria Ratai
    Neuroradiology Division, Department of Radiology and Athinoula A Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Charlestown, Massachusetts, USA
    Magn Reson Med 66:625-34. 2011

Collaborators

Detail Information

Publications21

  1. pmc Proton MR spectroscopic imaging of rhesus macaque brain in vivo at 7T
    Oded Gonen
    Department of Radiology, New York University School of Medicine, New York, New York 10016, USA
    Magn Reson Med 59:692-9. 2008
    ..Their metabolites' linewidths, 9+/-2 Hz, yield excellent spectral resolution as well. These results indicate that 3D (1)H-MRSI can be integrated into comprehensive MR studies in primates at such high fields...
  2. pmc Metabolic markers of neuronal injury correlate with SIV CNS disease severity and inoculum in the macaque model of neuroAIDS
    Margaret R Lentz
    Massachusetts General Hospital, Department of Neuroradiology, Boston, Massachusetts 02114 2696, USA
    Magn Reson Med 59:475-84. 2008
    ..In considering therapy for neuroAIDS the findings here support prevention of the encephalitic process, but suggest that suppressing the formation of multinucleated giant cells alone would be insufficient to prevent neuronal injury...
  3. pmc Factor analysis reveals differences in brain metabolism in macaques with SIV/AIDS and those with SIV-induced encephalitis
    Margaret R Lentz
    Department of Neuroradiology A A Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Charlestown, MA 02129, USA
    NMR Biomed 21:878-87. 2008
    ..These results suggest that the divergent pathways of N-acetylaspartate and creatine in this disease may enable the commonly reported ratio N-acetylaspartate/creatine to be a more sensitive marker of disease severity...
  4. pmc Magnetic resonance spectroscopy as an early indicator of response to anti-angiogenic therapy in patients with recurrent glioblastoma: RTOG 0625/ACRIN 6677
    Eva Maria Ratai
    A A Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Department of Radiology, Neuroradiology Division, Harvard Medical School, Building 149, 13th Street, Room 2301, Charlestown, MA 02129, USA
    Neuro Oncol 15:936-44. 2013
    ..The prognosis for patients with recurrent glioblastoma remains poor. The purpose of this study was to assess the potential role of MR spectroscopy as an early indicator of response to anti-angiogenic therapy...
  5. pmc A prospective longitudinal in vivo 1H MR spectroscopy study of the SIV/macaque model of neuroAIDS
    Robert A Fuller
    Massachusetts General Hospital NMR Center and Neuroradiology Division, Harvard Medical School, Charlestown, MA, USA
    BMC Neurosci 5:10. 2004
    ..Our goal was to undertsand the dynamics of cerebral injury by performing a longitudinal in vivo 1H MRS study of the SIV/macaque model of neuroAIDS...
  6. pmc Proton magnetic resonance spectroscopy reveals neuroprotection by oral minocycline in a nonhuman primate model of accelerated NeuroAIDS
    Eva Maria Ratai
    AA Martinos Center for Biomedical Imaging and Neuroradiology Division, Massachusetts General Hospital, Charlestown, Massachusetts, United States of America
    PLoS ONE 5:e10523. 2010
    ....
  7. pmc Automatic repositioning of MRSI voxels in longitudinal studies: impact on reproducibility of metabolite concentration measurements
    Eva Maria Ratai
    Massachusetts General Hospital, A A Martinos Center for Biomedical Imaging, Department of Radiology and Neuroradiology Division, Charlestown, Massachusetts 02129, USA
    J Magn Reson Imaging 27:1188-93. 2008
    ..However, one source of variability in such exams arises from imperfect relocalization of the MRSI grid in the follow-up exams...
  8. pmc In vivo proton magnetic resonance spectroscopy reveals region specific metabolic responses to SIV infection in the macaque brain
    Eva Maria Ratai
    Neuroradiology Division, Department of Radiology and A A Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Charlestown, Massachusetts 02129, USA
    BMC Neurosci 10:63. 2009
    ..Metabolic changes in the frontal cortex, basal ganglia and white matter in 18 SIV-infected macaques were investigated using MRS during the first month of infection...
  9. pmc Brain metabolites B1-corrected proton T1 mapping in the rhesus macaque at 3 T
    Songtao Liu
    Department of Radiology, New York University School of Medicine, New York, New York, USA
    Magn Reson Med 63:865-71. 2010
    ....
  10. pmc Brain creatine elevation and N-Acetylaspartate reduction indicates neuronal dysfunction in the setting of enhanced glial energy metabolism in a macaque model of neuroAIDS
    Eva Maria Ratai
    Neuroradiology Division, Department of Radiology and Athinoula A Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Charlestown, Massachusetts, USA
    Magn Reson Med 66:625-34. 2011
    ..Given these data, elevated creatine may reflect enhanced high-energy phosphate turnover in highly metabolizing activated astrocytes and microglia...
  11. pmc Metabolite proton T(2) mapping in the healthy rhesus macaque brain at 3 T
    Songtao Liu
    Department of Radiology, New York University School of Medicine, New York, New York 10016, USA
    Magn Reson Med 62:1292-9. 2009
    ....
  12. doi request reprint Structure-specific glial response in a macaque model of neuroAIDS: multivoxel proton magnetic resonance spectroscopic imaging at 3 Tesla
    William E Wu
    aDepartment of Radiology, New York University School of Medicine, New York, New York bMassachusetts General Hospital, Athinoula A Martinos Center for Biomedical Imaging and Neuroradiology Division, Charlestown, Massachusetts, USA
    AIDS 27:2519-28. 2013
    ....
  13. pmc Cross-sectional and longitudinal reproducibility of rhesus macaque brain metabolites: a proton MR spectroscopy study at 3 T
    William E Wu
    Department of Radiology, New York University School of Medicine, New York, New York 10016, USA
    Magn Reson Med 65:1522-31. 2011
    ....
  14. pmc Minocycline inhibition of monocyte activation correlates with neuronal protection in SIV neuroAIDS
    Jennifer H Campbell
    Department of Biology, Boston College, Chestnut Hill, Massachusetts, United States of America
    PLoS ONE 6:e18688. 2011
    ..Minocycline is a tetracycline antibiotic that has been proposed as a potential conjunctive therapy for HIV-1 associated cognitive disorders. Precise mechanism(s) of minocycline's functions are not well defined...
  15. pmc Regional metabolite T2 in the healthy rhesus macaque brain at 7T
    Songtao Liu
    Department of Radiology, New York University School of Medicine, New York, New York, USA
    Magn Reson Med 59:1165-9. 2008
    ..The T(2) histograms from 320 voxels in each animal for NAA, Cr, and Cho were similar in position and shape, indicating that they are potentially characteristic of "healthy" in this species...
  16. pmc Spectroscopic imaging with improved gradient modulated constant adiabaticity pulses on high-field clinical scanners
    Ovidiu C Andronesi
    Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Boston, MA 02114, USA
    J Magn Reson 203:283-93. 2010
    ..GOIA-WURST pulse tested in this work shows that reliable spectroscopic imaging could be obtained in routine clinical setup and might facilitate the use of clinical spectroscopy...
  17. pmc Serial magnetic resonance spectroscopy reveals a direct metabolic effect of cediranib in glioblastoma
    Heisoog Kim
    Massachusetts Institute of Technology, Department of Nuclear Science and Engineering Health Science and Technology, Cambridge, Massachusetts, USA
    Cancer Res 71:3745-52. 2011
    ..Further study is needed to confirm these findings...
  18. pmc A phase I, pharmacokinetic, dosage escalation study of creatine monohydrate in subjects with amyotrophic lateral sclerosis
    Nazem Atassi
    Neurology Clinical Trials Unit NCTU, Massachusetts General Hospital, 13th Street, Charlestown, MA 02129, USA
    Amyotroph Lateral Scler 11:508-13. 2010
    ..Creatine appears to cross the blood-brain barrier, and oral administration of 15 g b.i.d. is associated with increased in vivo brain creatine concentrations and decreased glutamate concentrations...
  19. doi request reprint 7-T MRI of the spinal cord can detect lateral corticospinal tract abnormality in amyotrophic lateral sclerosis
    Julien Cohen-Adad
    AA Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Charlestown, Massachusetts, USA
    Muscle Nerve 47:760-2. 2013
    ..Degeneration of the lateral corticospinal tract (CST) is a key finding in ALS cervical spinal cord autopsies. We hypothesized that in vivo ultra-high-field MRI of the cervical spinal cord can detect abnormality in the CST...
  20. doi request reprint The use of magnetic resonance spectroscopy in the evaluation of epilepsy
    Paul A Caruso
    Division of Neuroradiology, Department of Radiology, Harvard Medical School, Massachusetts General Hospital, Boston, MA 02114, USA
    Neuroimaging Clin N Am 23:407-24. 2013
    ..Single-voxel MRS with echo time of 35 milliseconds may be used for this purpose as a quick screening tool in the epilepsy imaging protocol. MRS is useful in the evaluation of both focal and generalized epilepsy. ..
  21. pmc In vivo 1D and 2D correlation MR spectroscopy of the soleus muscle at 7T
    Saadallah Ramadan
    Centre for Clinical Spectroscopy, Department of Radiology, Brigham and Women s Hospital, Harvard Medical School, 4 Blackfan St, H I M, 8th Floor, Boston, MA 02115, USA
    J Magn Reson 204:91-8. 2010
    ....