Zivotije Radisavljevic

Summary

Affiliation: Harvard University
Country: USA

Publications

  1. doi request reprint AKT as locus of fragility in robust cancer system
    Ziv Radisavljevic
    Department of Surgery, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA
    J Cell Biochem 104:2071-7. 2008
  2. ncbi request reprint Signaling through Cdk2, importin-alpha and NuMA is required for H2O2-induced mitosis in primary type II pneumocytes
    Ziv Manasija Radisavljevic
    Department of Environmental Health, Physiology Program, Harvard University, School of Public Health, 665 Huntington Avenue, Boston, MA 02115, USA
    Biochim Biophys Acta 1640:163-70. 2003
  3. ncbi request reprint Nitric oxide suppression triggers apoptosis through the FKHRL1 (FOXO3A)/ROCK kinase pathway in human breast carcinoma cells
    Zivotije Radisavljevic
    Department of Cancer Cell Biology, School of Public Health, Harvard University, Boston, Massachusetts 02115, USA
    Cancer 97:1358-63. 2003
  4. ncbi request reprint TOR kinase and Ran are downstream from PI3K/Akt in H2O2-induced mitosis
    Ziv Manasija Radisavljevic
    Harvard University, School of Public Health, Physiology Program, Boston, Massachusetts 02115, USA
    J Cell Biochem 91:1293-300. 2004
  5. ncbi request reprint Inactivated tumor suppressor Rb by nitric oxide promotes mitosis in human breast cancer cells
    Ziv Radisavljevic
    Department of Cancer Cell Biology, Harvard University, School of Public Health, Boston, Massachusetts 02115, USA
    J Cell Biochem 92:1-5. 2004
  6. ncbi request reprint Locus of fragility in robust breast cancer system
    Ziv Radisavljevic
    Department of Cancer Cell Biology, Harvard University, School of Public Health, Boston, Massachusetts 02115, USA
    J Cell Biochem 92:1020-4. 2004

Detail Information

Publications6

  1. doi request reprint AKT as locus of fragility in robust cancer system
    Ziv Radisavljevic
    Department of Surgery, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA
    J Cell Biochem 104:2071-7. 2008
    ..Simultaneously targeted loci represents new principles in cancer robustness chemotherapy by blocking cell proliferation, migration, angiogenesis and inducing rather slow then fast apoptosis leading to slow eradication of cancer...
  2. ncbi request reprint Signaling through Cdk2, importin-alpha and NuMA is required for H2O2-induced mitosis in primary type II pneumocytes
    Ziv Manasija Radisavljevic
    Department of Environmental Health, Physiology Program, Harvard University, School of Public Health, 665 Huntington Avenue, Boston, MA 02115, USA
    Biochim Biophys Acta 1640:163-70. 2003
    ..This pathway is essential for H(2)O(2)-induced mitosis in type II pneumocytes...
  3. ncbi request reprint Nitric oxide suppression triggers apoptosis through the FKHRL1 (FOXO3A)/ROCK kinase pathway in human breast carcinoma cells
    Zivotije Radisavljevic
    Department of Cancer Cell Biology, School of Public Health, Harvard University, Boston, Massachusetts 02115, USA
    Cancer 97:1358-63. 2003
    ..Because the human breast carcinoma T47D cell line releases a great amount of nitric oxide (NO), I investigated signaling of FKHRL1/ROCK [corrected] kinase during NO suppression...
  4. ncbi request reprint TOR kinase and Ran are downstream from PI3K/Akt in H2O2-induced mitosis
    Ziv Manasija Radisavljevic
    Harvard University, School of Public Health, Physiology Program, Boston, Massachusetts 02115, USA
    J Cell Biochem 91:1293-300. 2004
    ..These results indicate that H2O2-induced mitogenic signaling in primary type II pneumocytes is mediated by PI3K, Akt, mTOR-kinase, and Ran protein...
  5. ncbi request reprint Inactivated tumor suppressor Rb by nitric oxide promotes mitosis in human breast cancer cells
    Ziv Radisavljevic
    Department of Cancer Cell Biology, Harvard University, School of Public Health, Boston, Massachusetts 02115, USA
    J Cell Biochem 92:1-5. 2004
    ..These data indicate that NO induces cell proliferation through the Rb pathway. NO phosphorylates and inactivates tumor suppressor protein Rb inducing mitosis by the p53 independent pathway in breast cancer cell...
  6. ncbi request reprint Locus of fragility in robust breast cancer system
    Ziv Radisavljevic
    Department of Cancer Cell Biology, Harvard University, School of Public Health, Boston, Massachusetts 02115, USA
    J Cell Biochem 92:1020-4. 2004
    ..This tiny and trivial perturbation in breast cancer cells such as suppression of NO represents locus of fragility (weakness) and new approach for breast cancer chemotherapy...