A J Quayle

Summary

Affiliation: Harvard University
Country: USA

Publications

  1. pmc Gene expression, immunolocalization, and secretion of human defensin-5 in human female reproductive tract
    A J Quayle
    Department of Obstetrics, Gynecology and Reproductive Biology, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts, USA
    Am J Pathol 152:1247-58. 1998
  2. ncbi Detection of HIV-1-specific CTLs in the semen of HIV-infected individuals
    A J Quayle
    Department of Obstetrics, Gynecology and Reproductive Biology, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02115, USA
    J Immunol 161:4406-10. 1998
  3. pmc Human beta-defensin-1: an antimicrobial peptide of urogenital tissues
    E V Valore
    Department of Medicine, University of California, Los Angeles School of Medicine, Los Angeles, California 90095, USA
    J Clin Invest 101:1633-42. 1998

Collaborators

Detail Information

Publications3

  1. pmc Gene expression, immunolocalization, and secretion of human defensin-5 in human female reproductive tract
    A J Quayle
    Department of Obstetrics, Gynecology and Reproductive Biology, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts, USA
    Am J Pathol 152:1247-58. 1998
    ..We hypothesize that HD-5 is an intrinsic component of the female urogenital innate immune defense system and that its expression may be modulated by hormonal and proinflammatory factors...
  2. ncbi Detection of HIV-1-specific CTLs in the semen of HIV-infected individuals
    A J Quayle
    Department of Obstetrics, Gynecology and Reproductive Biology, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02115, USA
    J Immunol 161:4406-10. 1998
    ..In summary, our results demonstrate the presence of a broad CTL response to HIV in the urogenital tract and provide a rationale for further studies of local enhancement of genital mucosal responses by anti-HIV immunization...
  3. pmc Human beta-defensin-1: an antimicrobial peptide of urogenital tissues
    E V Valore
    Department of Medicine, University of California, Los Angeles School of Medicine, Los Angeles, California 90095, USA
    J Clin Invest 101:1633-42. 1998
    ..coli in unconcentrated (low conductance) urine, and the 36 aa form was microbicidal even in normal (high conductance) urine. Production of HBD-1 in the urogenital tract could contribute to local antimicrobial defense...