Xiao Bo Qiu

Summary

Affiliation: Harvard University
Country: USA

Publications

  1. pmc Nrdp1/FLRF is a ubiquitin ligase promoting ubiquitination and degradation of the epidermal growth factor receptor family member, ErbB3
    Xiao Bo Qiu
    Division of Signal Transduction, Beth Israel Deaconess Medical Center, Boston, MA 02115, USA
    Proc Natl Acad Sci U S A 99:14843-8. 2002
  2. pmc Nrdp1-mediated degradation of the gigantic IAP, BRUCE, is a novel pathway for triggering apoptosis
    Xiao Bo Qiu
    Department of Cell Biology, Harvard Medical School, Boston, MA 02115, USA
    EMBO J 23:800-10. 2004
  3. ncbi request reprint The membrane-associated inhibitor of apoptosis protein, BRUCE/Apollon, antagonizes both the precursor and mature forms of Smac and caspase-9
    Xiao Bo Qiu
    Department of Cell Biology, Harvard Medical School, Boston, Massachusetts 02115, USA
    J Biol Chem 280:174-82. 2005
  4. ncbi request reprint Interaction between c-Abl and Arg tyrosine kinases and proteasome subunit PSMA7 regulates proteasome degradation
    Xuan Liu
    Beijing Institute of Biotechnology, Beijing 100850, China
    Mol Cell 22:317-27. 2006
  5. pmc hRpn13/ADRM1/GP110 is a novel proteasome subunit that binds the deubiquitinating enzyme, UCH37
    Xiao Bo Qiu
    National Laboratory of Medical Molecular Biology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences and Peking Union Medical College, Tsinghua University, 5 Dongdan Santiao, Beijing, China
    EMBO J 25:5742-53. 2006
  6. ncbi request reprint New insights into the role of the ubiquitin-proteasome pathway in the regulation of apoptosis
    Cui Hua Liu
    National Laboratory of Medical Molecular Biology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences and Peking Union Medical College, Tsinghua University, Beijing, China
    Chang Gung Med J 30:469-79. 2007

Collaborators

Detail Information

Publications6

  1. pmc Nrdp1/FLRF is a ubiquitin ligase promoting ubiquitination and degradation of the epidermal growth factor receptor family member, ErbB3
    Xiao Bo Qiu
    Division of Signal Transduction, Beth Israel Deaconess Medical Center, Boston, MA 02115, USA
    Proc Natl Acad Sci U S A 99:14843-8. 2002
    ..These data indicate that Nrdp1 is a RING finger-type of ubiquitin ligase, which promotes degradation of ErbB3 by proteasomes and, thus, may be an important factor influencing cell growth...
  2. pmc Nrdp1-mediated degradation of the gigantic IAP, BRUCE, is a novel pathway for triggering apoptosis
    Xiao Bo Qiu
    Department of Cell Biology, Harvard Medical School, Boston, MA 02115, USA
    EMBO J 23:800-10. 2004
    ..Thus, BRUCE normally inhibits apoptosis, and Nrdp1 can be important in the initiation of apoptosis by catalyzing ubiquitination and degradation of BRUCE...
  3. ncbi request reprint The membrane-associated inhibitor of apoptosis protein, BRUCE/Apollon, antagonizes both the precursor and mature forms of Smac and caspase-9
    Xiao Bo Qiu
    Department of Cell Biology, Harvard Medical School, Boston, Massachusetts 02115, USA
    J Biol Chem 280:174-82. 2005
    ..These results suggest that the ability of BRUCE to antagonize both the precursor and mature forms of Smac and caspase-9 is an important mechanism for the prevention of apoptosis under normal conditions...
  4. ncbi request reprint Interaction between c-Abl and Arg tyrosine kinases and proteasome subunit PSMA7 regulates proteasome degradation
    Xuan Liu
    Beijing Institute of Biotechnology, Beijing 100850, China
    Mol Cell 22:317-27. 2006
    ....
  5. pmc hRpn13/ADRM1/GP110 is a novel proteasome subunit that binds the deubiquitinating enzyme, UCH37
    Xiao Bo Qiu
    National Laboratory of Medical Molecular Biology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences and Peking Union Medical College, Tsinghua University, 5 Dongdan Santiao, Beijing, China
    EMBO J 25:5742-53. 2006
    ..Thus in human 26S proteasomes, hRpn13 appears to be important for the binding of UCH37 to the 19S complex and for efficient proteolysis...
  6. ncbi request reprint New insights into the role of the ubiquitin-proteasome pathway in the regulation of apoptosis
    Cui Hua Liu
    National Laboratory of Medical Molecular Biology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences and Peking Union Medical College, Tsinghua University, Beijing, China
    Chang Gung Med J 30:469-79. 2007
    ....