Research Topics
Species | Rinaa S PungliaSummaryAffiliation: Harvard University Country: USA Publications
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Detail Information
Publications
Radiation therapy after mastectomy between 1991 and 1999 in elderly women: response to clinical trial informationRinaa S Punglia
Department of Radiation Oncology and Center for Outcomes and Policy Research, Division of Medical Oncology, Dana Farber Cancer Institute, Boston, MA 02115, USA
J Clin Oncol 24:3474-82. 2006..We sought to study the receipt of PMRT in elderly women in this period, using a population-based cohort of women with breast cancer...
Radiation therapy plus tamoxifen versus tamoxifen alone after breast-conserving surgery in postmenopausal women with stage I breast cancer: a decision analysisRinaa S Punglia
Joint Center for Radiation Therapy, Harvard Medical School, Boston, MA, USA
J Clin Oncol 21:2260-7. 2003....
Local therapy and survival in breast cancerRinaa S Punglia
Department of Radiation Oncology, Dana-Farber Cancer Institute, Boston, MA 02115, USA
N Engl J Med 356:2399-405. 2007
Impact of interval from breast conserving surgery to radiotherapy on local recurrence in older women with breast cancer: retrospective cohort analysisRinaa S Punglia
Department of Radiation Oncology, Dana Farber Cancer Institute, Boston, MA 02115, USA
BMJ 340:c845. 2010..To determine if the length of interval between breast conserving surgery and start of radiotherapy affects local recurrence and to identify factors that might be associated with delay in older women with breast cancer...
Radiation therapy for ductal carcinoma in situ: a decision analysisRinaa S Punglia
Department of Radiation Oncology, Dana Farber Cancer Institute Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA
Cancer 118:603-11. 2012..The benefit of adding radiation therapy after excision of ductal carcinoma in situ (DCIS) is widely debated. Randomized clinical trials are underpowered to delineate long-term outcomes after radiation...
Effect of distance to radiation treatment facility on use of radiation therapy after mastectomy in elderly womenRinaa S Punglia
Department of Radiation Oncology, Dana Farber Cancer Institute, Boston, MA 02115, USA
Int J Radiat Oncol Biol Phys 66:56-63. 2006..We sought to study the effect of distance to the nearest radiation treatment facility on the use of postmastectomy radiation therapy (PMRT) in elderly women...
The impact of tumor progesterone receptor status on optimal adjuvant endocrine therapy for postmenopausal patients with early-stage breast cancer: a decision analysisRinaa S Punglia
Department of Radiation Oncology, Dana-Farber Cancer Institute and Brigham and Women's Hospital, Boston, Massachusetts 02115, USA
Cancer 106:2576-82. 2006..Patients with ER+/PR+ tumors achieved optimal 10-year DFS estimates with tamoxifen followed by a crossover to AI therapy, whereas patients with ER+/PR- tumors fared best when they initiated treatment with AI...
Pharmacogenomic variation of CYP2D6 and the choice of optimal adjuvant endocrine therapy for postmenopausal breast cancer: a modeling analysisRinaa S Punglia
Department of Radiation Oncology, Dana Farber Cancer Institute, Brigham and Women s Hospital, 44 Binney St, Boston, MA 02115, USA
J Natl Cancer Inst 100:642-8. 2008....
Optimizing adjuvant endocrine therapy in postmenopausal women with early-stage breast cancer: a decision analysisRinaa S Punglia
Division of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA 02115, USA
J Clin Oncol 23:5178-87. 2005..5 years yields improved outcomes compared with either drug alone or cross-over treatment after 5 years of tamoxifen...
Accelerated partial breast irradiation using brachytherapy for breast cancer: patterns in utilization and guideline concordanceJona A Hattangadi
Harvard Radiation Oncology Program, Boston, MA, USA
J Natl Cancer Inst 104:29-41. 2012..We evaluated patterns of APBIb use with respect to 2009 American Society for Radiation Oncology consensus guidelines (ASTRO-G) in a population-based cohort...
Use of stereotactic radiosurgery for brain metastases from non-small cell lung cancer in the United StatesLia M Halasz
Department of Radiation Oncology, University of Washington, Seattle, Washington, USA
Int J Radiat Oncol Biol Phys 85:e109-16. 2013..The indications for treatment of brain metastases from non-small cell lung cancer (NSCLC) with stereotactic radiosurgery (SRS) remain controversial. We studied patterns, predictors, and cost of SRS use in elderly patients with NSCLC...
Cost effectiveness and screening interval of lipid screening in Hodgkin's lymphoma survivorsAileen B Chen
Department of Radiation Oncology, Dana Farber Cancer Institute and Brigham and Women s Hospital, Boston, MA 02115, USA
J Clin Oncol 27:5383-9. 2009..We evaluated the cost effectiveness of lipid screening in survivors of HL and compared different screening intervals...
Partial breast irradiation versus whole breast radiotherapy for early-stage breast cancer: a decision analysisDavid J Sher
Department of Radiation Oncology, Dana Farber Cancer Institute, Boston, MA 02115, USA
Int J Radiat Oncol Biol Phys 70:469-76. 2008..To compare the quality-adjusted life expectancy between women treated with partial breast irradiation (PBI) vs. whole breast radiotherapy (WBRT) for estrogen receptor-positive early-stage breast cancer...
Partial-breast irradiation versus whole-breast irradiation for early-stage breast cancer: a cost-effectiveness analysisDavid J Sher
Harvard Radiation Oncology Program, Boston, MA, USA
Int J Radiat Oncol Biol Phys 74:440-6. 2009..We aim to determine the incremental cost-effectiveness of PBI compared with whole-breast radiation therapy (WBRT) for estrogen receptor-positive postmenopausal women treated for early-stage breast cancer...
Pathologic characteristics of second breast cancers after breast conservation for ductal carcinoma in situNils D Arvold
Harvard Radiation Oncology Program, Harvard Medical School, Boston, Massachusetts, USA
Cancer 118:6022-30. 2012..The authors described the characteristics of SBC and examined associations between the pathologic features of SBC and index DCIS cases...
Influence of year of diagnosis, patient age, and sociodemographic status on recommending adjuvant radiation treatment for stage I testicular seminomaKaren E Hoffman
Department of Radiation Oncology, Brigham and Women s Hospital, 375 Longwood Ave, Boston, MA 02115, USA
J Clin Oncol 26:3937-42. 2008..This study evaluated ART trends in the United States and the impact of clinical and sociodemographic factors on ART recommendations...
Impact of margin status on local recurrence after mastectomy for ductal carcinoma in situStephanie K Childs
Harvard Radiation Oncology Program, Boston, MA 02115, USA
Int J Radiat Oncol Biol Phys 85:948-52. 2013..To examine the rate of local recurrence according to the margin status for patients with pure ductal carcinoma in situ (DCIS) treated by mastectomy...
Cost-effectiveness analysis of computerized tomography in the routine follow-up of patients after primary treatment for Hodgkin's diseaseBeverly A Guadagnolo
Joint Center for Radiation Therapy Harvard Radiation Oncology Program, Harvard School of Public Health, Harvard University, Boston, MA 02215, USA
J Clin Oncol 24:4116-22. 2006..To estimate the clinical benefits and cost effectiveness of computed tomography (CT) in the follow-up of patients with complete response (CR) after treatment for Hodgkin's disease (HD)...
Factors associated with guideline-concordant use of radiotherapy after mastectomy in the national comprehensive cancer networkRinaa S Punglia
Dana Farber Cancer Institute, Boston, MA, USA
Int J Radiat Oncol Biol Phys 72:1434-40. 2008....
Improved outcomes of breast-conserving therapy for patients with ductal carcinoma in situLia M Halasz
Harvard Radiation Oncology Program, Boston, MA, USA
Int J Radiat Oncol Biol Phys 82:e581-6. 2012..We sought to determine the following: LR rates with this more modern approach; the relation between LR and HER-2 status; and clinical and pathologic factors associated with HER-2(+) DCIS...
Adjuvant therapy for elderly patients with resected gastric adenocarcinoma: population-based practices and treatment effectivenessKaren E Hoffman
Department of Radiation Oncology, Brigham and Women s Hospital and Dana Farber Cancer Institute, Boston, Massachusetts, USA
Cancer 118:248-57. 2012..A study was undertaken to determine the survival benefit of postoperative chemoradiation therapy for elderly patients with resected gastric adenocarcinoma...
Impact of age, benign prostatic hyperplasia, and cancer on prostate-specific antigen levelRinaa S Punglia
Department of Radiation Oncology, Brigham and Women's Hospital, Boston, MA 02115, USA
Cancer 106:1507-13. 2006..Therefore, the current threshold of 4.0 ng/mL should not be applied indiscriminately...
Effect of very small tumor size on cancer-specific mortality in node-positive breast cancerJennifer Y Wo
Dana Farber Cancer Institute Brigham and Women s Hospital, Boston, MA 02115, USA
J Clin Oncol 29:2619-27. 2011..In particular, we evaluated whether very small tumor size may predict for increased BCSM relative to larger tumors in patients with extensive LN involvement...
Cost-effectiveness analysis of stereotactic body radiotherapy and radiofrequency ablation for medically inoperable, early-stage non-small cell lung cancerDavid J Sher
Department of Radiation Oncology, Dana Farber Cancer Institute Brigham and Women s Hospital, Boston, MA 02115, USA
Int J Radiat Oncol Biol Phys 81:e767-74. 2011..Radiofrequency ablation (RFA) has also been investigated as a less costly, single-day therapy that thermally ablates small, peripheral tumors. The cost-effectiveness of these three techniques has never been compared...
Variability among breast radiation oncologists in delineation of the postsurgical lumpectomy cavityDaniel M Landis
Joint Center for Radiation Therapy Residency Training Program, Harvard Medical School, Brigham and Women s Hospital, Boston, MA, USA
Int J Radiat Oncol Biol Phys 67:1299-308. 2007..We examined the interobserver variability in delineation of the lumpectomy cavity among four academic radiation oncologists who specialize in the treatment of breast cancer...
Prostate-specific antigen velocity and the detection of gleason score 7 to 10 prostate cancerRinaa S Punglia
Department of Radiation Oncology, Brigham and Women s Hospital and Dana Farber Cancer Institute, Boston, Massachusetts 02115, USA
Cancer 110:1973-8. 2007..In this study, the authors evaluated whether PSA velocity was associated with prostate cancer detection and grade at diagnosis after adjusting for established predictors...
Trade-offs associated with axillary lymph node dissection with breast irradiation versus breast irradiation alone in patients with a positive sentinel node in relation to the risk of non-sentinel node involvement: implications of ACOSOG Z0011Monica S Krishnan
Harvard Radiation Oncology Program, Boston, MA, USA
Breast Cancer Res Treat 138:205-13. 2013..6 % or lymphedema risk with ALND is under 10 %. Patients eligible for Z0011 but at a higher risk of residual nodal disease following BCS and positive SLNB may benefit from ALND + BRT, rather than BRT alone...
Should a sentinel node biopsy be performed in patients with high-risk breast cancer?Kenneth D Westover
Harvard Radiation Oncology Program, Boston, MA 02115, USA
Int J Breast Cancer 2011:973245. 2011..This tool may be useful in identifying patients who should have expanded upfront exploration of the axilla or comprehensive axillary irradiation...
Effect of verification bias on screening for prostate cancer by measurement of prostate-specific antigenRinaa S Punglia
Joint Center for Radiation Therapy, Harvard Medical School, Boston, USA
N Engl J Med 349:335-42. 2003..CONCLUSIONS: A lower threshold level of PSA for recommending prostate biopsy, particularly in younger men, may improve the clinical value of the PSA test...
Integrating surgery and radiotherapy to reduce toxicity while maintaining local control for breast cancer: a fine balanceRinaa S Punglia
Ann Surg Oncol 9:526-8. 2002
