Affiliation: Harvard University
Pourquie O, Brown K. Editorial changes. Development. 2017;: pubmed publisher
..They will both be greatly missed, but will maintain connections with and continue to provide input on the journal as members of our Editorial Advisory Board. ..
Pourquie O. Somite formation in the chicken embryo. Int J Dev Biol. 2018;62:57-62 pubmed publisher
..In this review, we will discuss how studies on somites in avian embryos have contributed to our understanding of key developmental processes such as segmentation, control of bilateral symmetry or axis regionalization. ..
Pourquie O, Al Tanoury Z, Chal J. The Long Road to Making Muscle In Vitro. Curr Top Dev Biol. 2018;129:123-142 pubmed publisher
..These new in vitro systems now open the possibility to better understand human myogenesis and to develop in vitro disease models as well as cell therapy approaches. ..
PourquiÃ© O. Standing Up for Sticklebacks. Cell. 2016;164:9-10 pubmed publisher
..Indjeian et al. now uncover how the cis regulation of a gene controls skeletal variation in fish and might have contributed to the evolution of bipedalism in humans. ..
Chal J, Guillot C, Pourquie O. PAPC couples the segmentation clock to somite morphogenesis by regulating N-cadherin-dependent adhesion. Development. 2017;144:664-676 pubmed publisher
..Thus, periodic expression of PAPC in the anterior PSM triggers rhythmic endocytosis of CDH2, allowing for segmental de-adhesion and individualization of somites. ..
Oginuma M, Moncuquet P, Xiong F, Karoly E, Chal J, Guevorkian K, et al
. A Gradient of Glycolytic Activity Coordinates FGF and Wnt Signaling during Elongation of the Body Axis in Amniote Embryos. Dev Cell. 2017;40:342-353.e10 pubmed publisher
..Our results suggest that glycolysis in the tail bud coordinates Wnt and FGF signaling to promote elongation of the embryonic axis. ..
Vilhais Neto G, Fournier M, Plassat J, Sardiu M, Saraf A, Garnier J, et al
. The WHHERE coactivator complex is required for retinoic acid-dependent regulation of embryonic symmetry. Nat Commun. 2017;8:728 pubmed publisher
..Here, the authors use a proteomic approach to identify a protein complex of Wdr5, Hdac1, Hdac2 that act together with RA and coactivator Rere/Atrophin2 and a histone methyltransferase Ehmt2 to regulate embryonic symmetry. ..