- EBV nuclear antigen EBNALP dismisses transcription repressors NCoR and RBPJ from enhancers and EBNA2 increases NCoR-deficient RBPJ DNA bindingDaniel Portal
Department of Medicine, Channing Laboratory, Brigham and Women s Hospital and Harvard University, Boston, MA 02215, USA
Proc Natl Acad Sci U S A 108:7808-13. 2011..These data strongly support a model in which EBNA2 association with NCoR-deficient RBPJ enhances transcription and EBNALP dismisses NCoR and RBPJ repressive complexes from enhancers to coactivate hes1 and arglu1 but not cd21 or cd23...
- Genome-wide analysis of Epstein-Barr virus Rta DNA bindingAndreas M F Heilmann
The Channing Laboratory, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts, USA
J Virol 86:5151-64. 2012..Our results represent the first characterization of Rta binding to the EBV genome during replication, identify previously unknown RREs, such as one in BALF5p, and highlight the complexity of EBV late gene promoter activation by Rta...