Daniel Portal

Summary

Affiliation: Harvard University
Country: USA

Publications

  1. pmc EBV nuclear antigen EBNALP dismisses transcription repressors NCoR and RBPJ from enhancers and EBNA2 increases NCoR-deficient RBPJ DNA binding
    Daniel Portal
    Department of Medicine, Channing Laboratory, Brigham and Women s Hospital and Harvard University, Boston, MA 02215, USA
    Proc Natl Acad Sci U S A 108:7808-13. 2011
  2. pmc Epstein-Barr virus nuclear antigen leader protein localizes to promoters and enhancers with cell transcription factors and EBNA2
    Daniel Portal
    Department of Medicine, Brigham and Women s Hospital, and Department of Microbiology and Immunobiology, Harvard University, Boston, MA 02115
    Proc Natl Acad Sci U S A 110:18537-42. 2013
  3. pmc Genome-wide analysis of Epstein-Barr virus Rta DNA binding
    Andreas M F Heilmann
    The Channing Laboratory, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts, USA
    J Virol 86:5151-64. 2012

Collaborators

  • Andreas M F Heilmann
  • Michael A Calderwood
  • Eric Johannsen
  • Yong Lu

Detail Information

Publications3

  1. pmc EBV nuclear antigen EBNALP dismisses transcription repressors NCoR and RBPJ from enhancers and EBNA2 increases NCoR-deficient RBPJ DNA binding
    Daniel Portal
    Department of Medicine, Channing Laboratory, Brigham and Women s Hospital and Harvard University, Boston, MA 02215, USA
    Proc Natl Acad Sci U S A 108:7808-13. 2011
    ..These data strongly support a model in which EBNA2 association with NCoR-deficient RBPJ enhances transcription and EBNALP dismisses NCoR and RBPJ repressive complexes from enhancers to coactivate hes1 and arglu1 but not cd21 or cd23...
  2. pmc Epstein-Barr virus nuclear antigen leader protein localizes to promoters and enhancers with cell transcription factors and EBNA2
    Daniel Portal
    Department of Medicine, Brigham and Women s Hospital, and Department of Microbiology and Immunobiology, Harvard University, Boston, MA 02115
    Proc Natl Acad Sci U S A 110:18537-42. 2013
    ..These data implicate LP and associated TFs and DNA looping factors CTCF, RAD21, SMC3, and YY1/INO80 chromatin-remodeling complexes in repressor depletion and gene activation necessary for lymphoblastoid cell line growth and survival...
  3. pmc Genome-wide analysis of Epstein-Barr virus Rta DNA binding
    Andreas M F Heilmann
    The Channing Laboratory, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts, USA
    J Virol 86:5151-64. 2012
    ..Our results represent the first characterization of Rta binding to the EBV genome during replication, identify previously unknown RREs, such as one in BALF5p, and highlight the complexity of EBV late gene promoter activation by Rta...