Tobias Pischon

Summary

Affiliation: Harvard University
Country: USA

Publications

  1. ncbi request reprint Adiponectin: stability in plasma over 36 hours and within-person variation over 1 year
    Tobias Pischon
    Department of Nutrition and Division of Biological Sciences, Harvard School of Public Health, Boston, MA 02115, USA
    Clin Chem 49:650-2. 2003
  2. ncbi request reprint Single nucleotide polymorphisms at the adiponectin locus and risk of coronary heart disease in men and women
    Tobias Pischon
    Department of Nutrition, Harvard School of Public Health, Boston, Massachusetts, USA
    Obesity (Silver Spring) 15:2051-60. 2007
  3. ncbi request reprint Soluble intercellular adhesion molecules, soluble vascular cell adhesion molecules, and risk of coronary heart disease
    Iris Shai
    Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts, USA
    Obesity (Silver Spring) 14:2099-106. 2006
  4. ncbi request reprint Leisure-time physical activity and reduced plasma levels of obesity-related inflammatory markers
    Tobias Pischon
    Department of Nutrition, Harvard School of Public Health, Boston, Massachusetts 02115, USA
    Obes Res 11:1055-64. 2003
  5. ncbi request reprint Association between dietary factors and plasma adiponectin concentrations in men
    Tobias Pischon
    Departments of Nutrition and Epidemiology, Harvard School of Public Health, Boston, MA, USA
    Am J Clin Nutr 81:780-6. 2005
  6. ncbi request reprint Drinking frequency, mediating biomarkers, and risk of myocardial infarction in women and men
    Kenneth J Mukamal
    Division of General Medicine and Primary Care, Beth Israel Deaconess Medical Center, Boston, MA 02215, USA
    Circulation 112:1406-13. 2005
  7. ncbi request reprint Inflammatory markers and the risk of coronary heart disease in men and women
    Jennifer K Pai
    Department of Epidemiology, Harvard School of Public Health, Boston, MA 02115, USA
    N Engl J Med 351:2599-610. 2004
  8. ncbi request reprint Moderate alcohol consumption and lower levels of inflammatory markers in US men and women
    Jennifer K Pai
    Department of Epidemiology, Harvard School of Public Health, Boston, MA 02115, USA
    Atherosclerosis 186:113-20. 2006
  9. ncbi request reprint Non-high-density lipoprotein cholesterol and apolipoprotein B in the prediction of coronary heart disease in men
    Tobias Pischon
    Department of Nutrition, Harvard School of Public Health, Boston, Massachusetts, USA
    Circulation 112:3375-83. 2005
  10. pmc Dietary intake of trans fatty acids and systemic inflammation in women
    Dariush Mozaffarian
    Channing Laboratory, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA, USA
    Am J Clin Nutr 79:606-12. 2004

Detail Information

Publications52

  1. ncbi request reprint Adiponectin: stability in plasma over 36 hours and within-person variation over 1 year
    Tobias Pischon
    Department of Nutrition and Division of Biological Sciences, Harvard School of Public Health, Boston, MA 02115, USA
    Clin Chem 49:650-2. 2003
  2. ncbi request reprint Single nucleotide polymorphisms at the adiponectin locus and risk of coronary heart disease in men and women
    Tobias Pischon
    Department of Nutrition, Harvard School of Public Health, Boston, Massachusetts, USA
    Obesity (Silver Spring) 15:2051-60. 2007
    ..The objective was to examine the association of 5 common single nucleotide polymorphisms (SNPs) at the adiponectin locus with risk of coronary heart disease (CHD) in men and women...
  3. ncbi request reprint Soluble intercellular adhesion molecules, soluble vascular cell adhesion molecules, and risk of coronary heart disease
    Iris Shai
    Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts, USA
    Obesity (Silver Spring) 14:2099-106. 2006
    ....
  4. ncbi request reprint Leisure-time physical activity and reduced plasma levels of obesity-related inflammatory markers
    Tobias Pischon
    Department of Nutrition, Harvard School of Public Health, Boston, Massachusetts 02115, USA
    Obes Res 11:1055-64. 2003
    ..Furthermore, we examined the relationship between physical activity and insulin sensitivity (insulin, C-peptide, and hemoglobin A(1c) levels) and whether inflammatory markers mediate this association...
  5. ncbi request reprint Association between dietary factors and plasma adiponectin concentrations in men
    Tobias Pischon
    Departments of Nutrition and Epidemiology, Harvard School of Public Health, Boston, MA, USA
    Am J Clin Nutr 81:780-6. 2005
    ..However, little is known about dietary predictors of plasma adiponectin concentrations in humans...
  6. ncbi request reprint Drinking frequency, mediating biomarkers, and risk of myocardial infarction in women and men
    Kenneth J Mukamal
    Division of General Medicine and Primary Care, Beth Israel Deaconess Medical Center, Boston, MA 02215, USA
    Circulation 112:1406-13. 2005
    ....
  7. ncbi request reprint Inflammatory markers and the risk of coronary heart disease in men and women
    Jennifer K Pai
    Department of Epidemiology, Harvard School of Public Health, Boston, MA 02115, USA
    N Engl J Med 351:2599-610. 2004
    ..The value of these inflammatory markers as independent predictors remains controversial...
  8. ncbi request reprint Moderate alcohol consumption and lower levels of inflammatory markers in US men and women
    Jennifer K Pai
    Department of Epidemiology, Harvard School of Public Health, Boston, MA 02115, USA
    Atherosclerosis 186:113-20. 2006
    ..Moderate alcohol consumption is associated with substantially lower risk of cardiovascular disease (CVD). We assessed the relationship between alcohol intake and inflammatory markers to partially explain this beneficial effect...
  9. ncbi request reprint Non-high-density lipoprotein cholesterol and apolipoprotein B in the prediction of coronary heart disease in men
    Tobias Pischon
    Department of Nutrition, Harvard School of Public Health, Boston, Massachusetts, USA
    Circulation 112:3375-83. 2005
    ....
  10. pmc Dietary intake of trans fatty acids and systemic inflammation in women
    Dariush Mozaffarian
    Channing Laboratory, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA, USA
    Am J Clin Nutr 79:606-12. 2004
    ..Systemic inflammation may be involved in the pathogenesis of such conditions; however, relations between TFA intake and systemic inflammation are not well established...
  11. ncbi request reprint Plasma adiponectin levels and risk of myocardial infarction in men
    Tobias Pischon
    Department of Nutrition, Harvard School of Public Health, Channing Laboratory, Boston, Mass 02115, USA
    JAMA 291:1730-7. 2004
    ..Adiponectin, a recently discovered adipocyte-derived peptide, is involved in the regulation of insulin sensitivity and lipid oxidation and, purportedly, in the development of atherosclerosis and coronary heart disease in humans...
  12. ncbi request reprint Fructose, glycemic load, and quantity and quality of carbohydrate in relation to plasma C-peptide concentrations in US women
    Tianying Wu
    Department of Nutrition, Harvard School of Public Health, Boston, USA
    Am J Clin Nutr 80:1043-9. 2004
    ..However, associations between fructose and the quantity and quality of total carbohydrate intake in relation to C-peptide concentrations have not been adequately examined...
  13. ncbi request reprint Peroxisome proliferator-activated receptor-gamma2 P12A polymorphism and risk of coronary heart disease in US men and women
    Tobias Pischon
    Department of Nutrition and Epidemiology, Harvard School of Public Health, Boston, Mass, USA
    Arterioscler Thromb Vasc Biol 25:1654-8. 2005
    ..Studies suggest that the A12 allele is associated with reduced risk of type 2 diabetes; however, data on the risk of coronary heart disease (CHD) are scarce and controversial...
  14. pmc Hepatocellular carcinoma risk factors and disease burden in a European cohort: a nested case-control study
    Dimitrios Trichopoulos
    Department of Epidemiology, Harvard School of Public Health, 677 Huntington Avenue, Boston, MA 02115, USA
    J Natl Cancer Inst 103:1686-95. 2011
    ..To date, no attempt has been made to systematically determine the apportionment of the hepatocellular carcinoma burden in Europe or North America among established risk factors...
  15. ncbi request reprint Habitual dietary intake of n-3 and n-6 fatty acids in relation to inflammatory markers among US men and women
    Tobias Pischon
    Department of Nutrition, Harvard School of Public Health, 665 Huntington Ave, Boston, Mass 02115, USA
    Circulation 108:155-60. 2003
    ..Polyunsaturated fatty acid intake favorably affects chronic inflammatory-related diseases such as cardiovascular disease; however, high intake of n-6 fatty acids may attenuate the known beneficial effects of n-3 fatty acids...
  16. doi request reprint Anthropometric characteristics and non-Hodgkin's lymphoma and multiple myeloma risk in the European Prospective Investigation into Cancer and Nutrition (EPIC)
    Julie A Britton
    Department of Epidemiology and Public Health, Imperial College London, Room 151, St Mary s Campus, Norfolk Place W2 1PG, London, UK
    Haematologica 93:1666-77. 2008
    ..It has been hypothesized that this may be due, in part, to the parallel rising prevalence of obesity. It is biologically plausible that anthropometric characteristics can infuence the risk of non-Hodgkin's lymphoma and multiple myeloma...
  17. ncbi request reprint Plasma carotenoids, retinol, and tocopherols and the risk of prostate cancer in the European Prospective Investigation into Cancer and Nutrition study
    Timothy J Key
    Cancer Research UK Epidemiology Unit, University of Oxford, Oxford, United Kingdom
    Am J Clin Nutr 86:672-81. 2007
    ..Previous studies suggest that high plasma concentrations of carotenoids, retinol, or tocopherols may reduce the risk of prostate cancer...
  18. ncbi request reprint EPIC-Heart: the cardiovascular component of a prospective study of nutritional, lifestyle and biological factors in 520,000 middle-aged participants from 10 European countries
    John Danesh
    EPIC Heart Secretariat, Department of Public Health and Primary Care, Strangeways Research Laboratory, University of Cambridge, Worts Causeway, Cambridge, CB1 8RN, UK
    Eur J Epidemiol 22:129-41. 2007
    ..Subsequent analyses will extend this approach to non-fatal cardiovascular outcomes and to further dietary, biochemical and genetic factors...
  19. ncbi request reprint Anthropometric factors and risk of endometrial cancer: the European prospective investigation into cancer and nutrition
    Christine Friedenreich
    Division of Population Health and Information, Alberta Cancer Board, T2N 4N2, Calgary, Alberta, Canada
    Cancer Causes Control 18:399-413. 2007
    ..To examine the association between anthropometry and endometrial cancer, particularly by menopausal status and exogenous hormone use subgroups...
  20. ncbi request reprint Potentially modifiable classic risk factors and their impact on incident myocardial infarction: results from the EPIC-Potsdam study
    Christin Heidemann
    Department of Epidemiology, German Institute of Human Nutrition Potsdam Rehbruecke, Nuthetal, Germany
    Eur J Cardiovasc Prev Rehabil 14:65-71. 2007
    ..Prospective data on the importance of established risk factors for myocardial infarction in Germany are sparse...
  21. ncbi request reprint Serum C-peptide, IGFBP-1 and IGFBP-2 and risk of colon and rectal cancers in the European Prospective Investigation into Cancer and Nutrition
    Mazda Jenab
    Nutrition and Hormones Group, IARC WHO, Lyon, France
    Int J Cancer 121:368-76. 2007
    ..No clear colorectal cancer risk associations were observed for IGFBP-1 or -2. This large prospective study confirms that hyperinsulinemia, as determined by C-peptide levels, is associated with an increased colorectal cancer risk...
  22. ncbi request reprint Within-subject variation of plasma resistin levels over a 1-year period
    Cornelia Weikert
    German Institute of Human Nutrition, Potsdam Rehbrucke, Nuthetal, Germany
    Clin Chem Lab Med 45:899-902. 2007
    ..Resistin, a recently discovered hormone, is purportedly involved in metabolic and inflammatory processes in humans and may thus be an important marker to assess disease risk in large-scale epidemiological studies...
  23. ncbi request reprint Blood pressure and risk of renal cell carcinoma in the European prospective investigation into cancer and nutrition
    Steffen Weikert
    Department of Epidemiology, German Institute of Human Nutrition Potsdam Rehbruecke, Nuthetal, Germany
    Am J Epidemiol 167:438-46. 2008
    ..These results support the hypothesis that hypertension, rather than its medications, increases the risk of RCC in both sexes, while effective blood pressure control may lower the risk...
  24. ncbi request reprint Comparison of relative and attributable risk of myocardial infarction and stroke according to C-reactive protein and low-density lipoprotein cholesterol levels
    Tobias Pischon
    Department of Epidemiology, German Institute of Human Nutrition DIfE, Potsdam Rehbruecke, Arthur Scheunert Allee 114 116, 14558, Nuthetal, Germany
    Eur J Epidemiol 22:429-38. 2007
    ..Consideration of LDL-C beyond smoking, diabetes and hypertension may increase the PAF of MI slightly more than CRP. In contrast, consideration of CRP but not of LDL-C may increase the PAF of stroke beyond these factors...
  25. ncbi request reprint Body size and risk of colon and rectal cancer in the European Prospective Investigation Into Cancer and Nutrition (EPIC)
    Tobias Pischon
    Department of Epidemiology, German Institute of Human Nutrition DIfE, Potsdam Rehbruecke, Arthur Scheunert Allee 114 116, 14558 Nuthetal, Germany
    J Natl Cancer Inst 98:920-31. 2006
    ..This discrepancy may be related to differences in fat distribution between sexes or to the use of hormone replacement therapy (HRT) in women...
  26. pmc Obesity prevalence from a European perspective: a systematic review
    Anne Berghöfer
    Institute for Social Medicine, Epidemiology and Health Economics, Charite University Medical Center, Berlin, Germany
    BMC Public Health 8:200. 2008
    ..We therefore aimed to identify and discuss current epidemiological data on the prevalence of obesity in European countries...
  27. pmc Inflammation, the metabolic syndrome, and risk of coronary heart disease in women and men
    Tobias Pischon
    Department of Epidemiology, German Institute of Human Nutrition, Potsdam Rehbruecke, Arthur Scheunert Allee 114 116, 14558 Nuthetal, Germany
    Atherosclerosis 197:392-9. 2008
    ..This study examined whether inflammation adds to the prediction of coronary heart disease (CHD) beyond metabolic syndrome (MetS), and whether these associations differ between sexes...
  28. doi request reprint Plasma resistin levels and risk of myocardial infarction and ischemic stroke
    Cornelia Weikert
    Department of Epidemiology, German Institute of Human Nutrition, Arthur Scheunert Allee 114 116, Nuthetal, Germany
    J Clin Endocrinol Metab 93:2647-53. 2008
    ....
  29. ncbi request reprint Fruits and vegetables and renal cell carcinoma: findings from the European prospective investigation into cancer and nutrition (EPIC)
    Steffen Weikert
    Department of Epidemiology, German Institute of Human Nutrition Potsdam Rehbruecke, Nuthetal
    Int J Cancer 118:3133-9. 2006
    ..The relationship of specific fruit and vegetable subgroups with RCC risk warrant further investigation...
  30. ncbi request reprint Physical activity and risk of endometrial cancer: the European prospective investigation into cancer and nutrition
    Christine Friedenreich
    Division of Population Health and Information, Alberta Cancer Board, Calgary, Alberta, Canada
    Int J Cancer 121:347-55. 2007
    ..The relative risk reductions are most apparent for household activities...
  31. doi request reprint Obesity and cancer
    Tobias Pischon
    Department of Epidemiology, German Institute of Human Nutrition Potsdam Rehbruecke, 14558 Nuthetal, Germany
    Proc Nutr Soc 67:128-45. 2008
    ..Recent research also suggests that adipose tissue-derived hormones and cytokines (adipokines), such as leptin, adiponectin and inflammatory markers, may reflect mechanisms linked to tumourigenesis...
  32. doi request reprint Circulating concentrations of folate and vitamin B12 in relation to prostate cancer risk: results from the European Prospective Investigation into Cancer and Nutrition study
    Mattias Johansson
    Department of Surgical and Perioperative Sciences, Urology and Andrology, Umea University, 901 85 Umea, Sweden
    Cancer Epidemiol Biomarkers Prev 17:279-85. 2008
    ..The aim of the present study was to investigate the relationship between prostate cancer risk and circulating concentrations of folate and vitamin B(12) in a large prospective cohort...
  33. ncbi request reprint Metabolic syndrome, plasma lipid, lipoprotein and glucose levels, and endometrial cancer risk in the European Prospective Investigation into Cancer and Nutrition (EPIC)
    Anne E Cust
    Nutrition and Hormones Unit, International Agency for Research on Cancer, Lyon, France
    Endocr Relat Cancer 14:755-67. 2007
    ..01). None of the associations differed significantly by fasting status. These findings suggest that metabolic abnormalities and obesity may act synergistically to increase endometrial cancer risk...
  34. ncbi request reprint Dietary fat intake and risk of prostate cancer in the European Prospective Investigation into Cancer and Nutrition
    Francesca L Crowe
    Cancer Research UK Epidemiology Unit, University of Oxford, Oxford, United Kingdom
    Am J Clin Nutr 87:1405-13. 2008
    ..However, the results from more recent prospective studies do not support this hypothesis, and the possible association between different food sources of fat and prostate cancer risk also remains unclear...
  35. ncbi request reprint Recent developments in the treatment of obesity-related hypertension
    Tobias Pischon
    Franz Volhard Clinic HELIOS Klinikum Berlin Buch, Charite, Medical Faculty of the Humboldt University Berlin, Max Delbruck Center for Molecular Medicine, Germany
    Curr Opin Nephrol Hypertens 11:497-502. 2002
    ..Obesity is a major public health issue, and hypertension is one of the most common associated co-morbidities. Here, recent developments in the treatment of obesity-related hypertension, published during the past year, are reviewed...
  36. doi request reprint A statistical test for the equality of differently adjusted incidence rate ratios
    Kurt Hoffmann
    Department of Epidemiology, German Institute of Human Nutrition Potsdam Rehbrucke, Nuthetal, Germany
    Am J Epidemiol 167:517-22. 2008
    ..The statistical method described may be helpful as an additional tool for analyzing epidemiologic cohort data and for interpreting results obtained from Cox regression models with adjustment for different covariates...
  37. ncbi request reprint Serum insulin-like growth factor (IGF)-I and IGF-binding protein-3 concentrations and prostate cancer risk: results from the European Prospective Investigation into Cancer and Nutrition
    Naomi E Allen
    Cancer Research UK Epidemiology Unit, University of Oxford, Oxford OX3 7LF, United Kingdom
    Cancer Epidemiol Biomarkers Prev 16:1121-7. 2007
    ..Some studies suggest that elevated serum insulin-like growth factor (IGF)-I concentrations are associated with an increased risk of prostate cancer and, in particular, with an increased risk of advanced-stage prostate cancer...
  38. ncbi request reprint Serum androgens and prostate cancer among 643 cases and 643 controls in the European Prospective Investigation into Cancer and Nutrition
    Ruth C Travis
    Cancer Research UK Epidemiology Unit, University of Oxford, Oxford, United Kingdom
    Int J Cancer 121:1331-8. 2007
    ....
  39. ncbi request reprint Effect of forced titration of nebivolol on response rate in obese hypertensive patients
    Tobias Pischon
    Am J Hypertens 16:98-100. 2003
  40. ncbi request reprint Paradoxical effect of sibutramine on autonomic cardiovascular regulation in obese hypertensive patients--sibutramine and blood pressure
    Andreas L Birkenfeld
    Franz Volhard Clinical Research Center, Medical Faculty of the Charité and HELIOS Klinikum, Berlin, Germany
    Clin Auton Res 15:200-6. 2005
    ..This notion has not been tested in overweight and obese patients...
  41. ncbi request reprint Body size and risk of renal cell carcinoma in the European Prospective Investigation into Cancer and Nutrition (EPIC)
    Tobias Pischon
    Department of Epidemiology, German Institute of Human Nutrition, Potsdam Rehbruecke, Germany
    Int J Cancer 118:728-38. 2006
    ..Our data give further credence to public health efforts aiming to reduce the prevalence of obesity to prevent RCC, in addition to other chronic diseases...
  42. ncbi request reprint Genetic variation in the growth hormone synthesis pathway in relation to circulating insulin-like growth factor-I, insulin-like growth factor binding protein-3, and breast cancer risk: results from the European prospective investigation into cancer and nu
    Federico Canzian
    Hormones and Cancer Team, International Agency for Research on Cancer, 150 cours Albert Thomas, F 69372 Lyon, France
    Cancer Epidemiol Biomarkers Prev 14:2316-25. 2005
    ....
  43. ncbi request reprint Association of plasma resistin levels with coronary heart disease in women
    Tobias Pischon
    Department of Epidemiology, German Institute of Human Nutrition, Potsdam Rehbruecke, Arthur Scheunert Allee 114 116, 14558 Nuthetal, Germany
    Obes Res 13:1764-71. 2005
    ..To examine the association between plasma resistin levels and the presence of coronary heart disease (CHD) in women...
  44. ncbi request reprint Anthropometry, physical activity, and the risk of pancreatic cancer in the European prospective investigation into cancer and nutrition
    Amy Berrington de Gonzalez
    Cancer Epidemiology Unit, University of Oxford, Richard Doll Building, Roosevelt Drive, Oxford OX3 7LF, United Kingdom
    Cancer Epidemiol Biomarkers Prev 15:879-85. 2006
    ..50-1.35 for most active versus inactive). Future studies should consider including measurements of waist and hip circumference, to further investigate the relationship between central adiposity and the risk of pancreatic cancer...
  45. ncbi request reprint Intake of fruits and vegetables and risk of cancer of the upper aero-digestive tract: the prospective EPIC-study
    Heiner Boeing
    Department of Epidemiology, German Institute of Human Nutrition, Potsdam Rehbrucke, Arthur Scheunert Allee 114 116, 14558, Nuthetal, Germany
    Cancer Causes Control 17:957-69. 2006
    ..Dietary recommendations should consider the potential benefit of increasing fruits and vegetables consumption for reducing the risk of cancers of the upper aero-digestive tract, particularly at low intake...
  46. ncbi request reprint Plasma adiponectin levels and endometrial cancer risk in pre- and postmenopausal women
    Anne E Cust
    Nutrition and Hormones Unit, International Agency for Research on Cancer, 69372 Lyon, France
    J Clin Endocrinol Metab 92:255-63. 2007
    ..Adiponectin, an adipocytokine secreted by adipose tissue, is decreased in obesity, insulin resistance, type 2 diabetes, and polycystic ovary syndrome, all of which are well-established risk factors for endometrial cancer...
  47. ncbi request reprint Physical activity and risk of colon and rectal cancers: the European prospective investigation into cancer and nutrition
    Christine Friedenreich
    Nutrition and Hormones Group, IARC, Lyon, France
    Cancer Epidemiol Biomarkers Prev 15:2398-407. 2006
    ..We found that physical activity reduced colon cancer risk, specifically for right-sided tumors and for lean participants, but not rectal cancer...
  48. ncbi request reprint Adiponectin and risk of acute coronary syndromes: defining the obesity phenotype
    Tobias Pischon
    Eur Heart J 28:274-5. 2007
  49. ncbi request reprint Letter by Pischon et al regarding article, "Adiponectin and coronary heart disease: a prospective study and meta-analysis"
    Tobias Pischon
    Circulation 115:e322; author reply e323. 2007
  50. ncbi request reprint Adiponectin: a promising marker for cardiovascular disease
    Tobias Pischon
    Clin Chem 52:797-9. 2006
  51. ncbi request reprint Fruit and vegetable consumption and lung cancer risk: updated information from the European Prospective Investigation into Cancer and Nutrition (EPIC)
    Jakob Linseisen
    Division of Clinical Epidemiology, German Cancer Research Centre, Heidelberg, Germany
    Int J Cancer 121:1103-14. 2007
    ..In addition to an overall inverse association with fruit intake, the results of this evaluation add evidence for a significant inverse association of vegetable consumption and lung cancer incidence in smokers...
  52. ncbi request reprint Optimizing blood pressure control in the obese patient
    Tobias Pischon
    Franz Volhard Clinic Charité, Wiltbergstrasse 50, 13125 Berlin, Germany
    Curr Hypertens Rep 4:358-62. 2002
    ..The role of antiobesity drugs in the management of the obese hypertensive patient also remains to be defined...