Mark C Pierce

Summary

Affiliation: Harvard University
Country: USA

Publications

  1. ncbi request reprint Advances in optical coherence tomography imaging for dermatology
    Mark C Pierce
    Wellman Center for Photomedicine Harvard Medical School, Massachusetts General Hospital, 50 Blossom Street, Boston, MA 02114, USA
    J Invest Dermatol 123:458-63. 2004
  2. ncbi request reprint Birefringence measurements in human skin using polarization-sensitive optical coherence tomography
    Mark C Pierce
    Harvard Medical School, Massachusetts General Hospital, Wellman Center for Photomedicine, 50 Blossom Street Boston, Massachusetts 02114, USA
    J Biomed Opt 9:287-91. 2004
  3. ncbi request reprint Collagen denaturation can be quantified in burned human skin using polarization-sensitive optical coherence tomography
    Mark C Pierce
    Wellman Center for Photomedicine, Harvard Medical School, Massachusetts General Hospital, Boston, MA 02114, USA
    Burns 30:511-7. 2004
  4. ncbi request reprint Comment on "Optical-fiber-based Mueller optical coherence tomography"
    B Hyle Park
    Harvard Medical School and Wellman Center for Photomedicine, Massachusetts General Hospital, 50 Blossom Street, BAR 7, Boston, Massachusetts 02114, USA
    Opt Lett 29:2873-4; discussion 2875-7. 2004
  5. ncbi request reprint Imaging the human vocal folds in vivo with optical coherence tomography: a preliminary experience
    Adam M Klein
    Department of Surgery, Harvard Medical School, Boston, Massachusetts, USA
    Ann Otol Rhinol Laryngol 115:277-84. 2006
  6. ncbi request reprint Optic axis determination accuracy for fiber-based polarization-sensitive optical coherence tomography
    B Hyle Park
    Wellman Center for Photomedicine, Massachusetts General Hospital, Harvard Medical School, 50 Blossom Street, BAR 7, Boston, Massachusetts 02114, USA
    Opt Lett 30:2587-9. 2005
  7. ncbi request reprint Spectral domain optical coherence tomography: ultra-high speed, ultra-high resolution ophthalmic imaging
    Teresa C Chen
    Department of Ophthalmology, Harvard Medical School, Boston, Mass, USA
    Arch Ophthalmol 123:1715-20. 2005
  8. ncbi request reprint Thickness and birefringence of healthy retinal nerve fiber layer tissue measured with polarization-sensitive optical coherence tomography
    Barry Cense
    Harvard Medical School and Wellman Center of Photomedicine, Massachusetts General Hospital, Boston, 02114, USA
    Invest Ophthalmol Vis Sci 45:2606-12. 2004
  9. pmc Measurement of collagen and smooth muscle cell content in atherosclerotic plaques using polarization-sensitive optical coherence tomography
    Seemantini K Nadkarni
    Department of Dermatology, Harvard Medical School and Massachusetts General Hospital, Boston, Massachusetts, USA
    J Am Coll Cardiol 49:1474-81. 2007
  10. ncbi request reprint Polarization-sensitive optical coherence tomography of invasive basal cell carcinoma
    John Strasswimmer
    Wellman Center of Photomedicine, Department of Dermatology, Massachusetts General Hospital, Harvard Medical School, 50 Blossom Street, Boston, Massachusetts 02114, USA
    J Biomed Opt 9:292-8. 2004

Detail Information

Publications15

  1. ncbi request reprint Advances in optical coherence tomography imaging for dermatology
    Mark C Pierce
    Wellman Center for Photomedicine Harvard Medical School, Massachusetts General Hospital, 50 Blossom Street, Boston, MA 02114, USA
    J Invest Dermatol 123:458-63. 2004
    ..In particular, combining the previously described structural and Doppler imaging functions with polarization-sensitive imaging increases the utility of the technique for rapid, non-invasive investigations in the skin...
  2. ncbi request reprint Birefringence measurements in human skin using polarization-sensitive optical coherence tomography
    Mark C Pierce
    Harvard Medical School, Massachusetts General Hospital, Wellman Center for Photomedicine, 50 Blossom Street Boston, Massachusetts 02114, USA
    J Biomed Opt 9:287-91. 2004
    ..Examples of PS-OCT images from skin sites following wound healing and repair are also presented and discussed...
  3. ncbi request reprint Collagen denaturation can be quantified in burned human skin using polarization-sensitive optical coherence tomography
    Mark C Pierce
    Wellman Center for Photomedicine, Harvard Medical School, Massachusetts General Hospital, Boston, MA 02114, USA
    Burns 30:511-7. 2004
    ..In conclusion, PS-OCT is capable of imaging and quantifying collagen denaturation in burned human skin, providing a new parameter against which post-injury outcome may be compared...
  4. ncbi request reprint Comment on "Optical-fiber-based Mueller optical coherence tomography"
    B Hyle Park
    Harvard Medical School and Wellman Center for Photomedicine, Massachusetts General Hospital, 50 Blossom Street, BAR 7, Boston, Massachusetts 02114, USA
    Opt Lett 29:2873-4; discussion 2875-7. 2004
    ..Opt. Lett. 25, 1355 (2000)]...
  5. ncbi request reprint Imaging the human vocal folds in vivo with optical coherence tomography: a preliminary experience
    Adam M Klein
    Department of Surgery, Harvard Medical School, Boston, Massachusetts, USA
    Ann Otol Rhinol Laryngol 115:277-84. 2006
    ....
  6. ncbi request reprint Optic axis determination accuracy for fiber-based polarization-sensitive optical coherence tomography
    B Hyle Park
    Wellman Center for Photomedicine, Massachusetts General Hospital, Harvard Medical School, 50 Blossom Street, BAR 7, Boston, Massachusetts 02114, USA
    Opt Lett 30:2587-9. 2005
    ..We discuss the accuracy of optic axis determination due to a fundamental limit on the accuracy with which a polarization state can be determined as a function of signal-to-noise ratio...
  7. ncbi request reprint Spectral domain optical coherence tomography: ultra-high speed, ultra-high resolution ophthalmic imaging
    Teresa C Chen
    Department of Ophthalmology, Harvard Medical School, Boston, Mass, USA
    Arch Ophthalmol 123:1715-20. 2005
    ..To introduce a new ophthalmic optical coherence tomography technology that allows unprecedented simultaneous ultra-high speed and ultra-high resolution...
  8. ncbi request reprint Thickness and birefringence of healthy retinal nerve fiber layer tissue measured with polarization-sensitive optical coherence tomography
    Barry Cense
    Harvard Medical School and Wellman Center of Photomedicine, Massachusetts General Hospital, Boston, 02114, USA
    Invest Ophthalmol Vis Sci 45:2606-12. 2004
    ..Early detection of RNFL changes may enable treatment to prevent permanent loss of vision. Polarization-sensitive optical coherence tomography (PS-OCT) can provide objective information on RNFL thickness and birefringence...
  9. pmc Measurement of collagen and smooth muscle cell content in atherosclerotic plaques using polarization-sensitive optical coherence tomography
    Seemantini K Nadkarni
    Department of Dermatology, Harvard Medical School and Massachusetts General Hospital, Boston, Massachusetts, USA
    J Am Coll Cardiol 49:1474-81. 2007
    ..The purpose of this study was to investigate the measurement of collagen and smooth muscle cell (SMC) content in atherosclerotic plaques using polarization-sensitive optical coherence tomography (PSOCT)...
  10. ncbi request reprint Polarization-sensitive optical coherence tomography of invasive basal cell carcinoma
    John Strasswimmer
    Wellman Center of Photomedicine, Department of Dermatology, Massachusetts General Hospital, Harvard Medical School, 50 Blossom Street, Boston, Massachusetts 02114, USA
    J Biomed Opt 9:292-8. 2004
    ..These results indicate that PS-OCT can identify features that distinguish normal skin from tumor and may have the potential to guide surgeons in the treatment of aggressive skin cancer...
  11. pmc Jones matrix analysis for a polarization-sensitive optical coherence tomography system using fiber-optic components
    B Hyle Park
    Wellman Center for Photomedicine, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts 02114, USA
    Opt Lett 29:2512-4. 2004
    ..The relative importance of diattenuation versus birefringence to angular displacement of Stokes vectors on a Poincaré sphere was quantified...
  12. ncbi request reprint In vivo birefringence and thickness measurements of the human retinal nerve fiber layer using polarization-sensitive optical coherence tomography
    Barry Cense
    Wellman Laboratories of Photomedicine, Harvard Medical School and Massachusetts General Hospital, 50 Blossom Street BAR 714, Boston, MA 02114, USA
    J Biomed Opt 9:121-5. 2004
    ..A trend in the preliminary measurements shows that the nerve fiber layer located inferior and superior to the optic nerve head is more birefringent than the thinner layer of nerve fiber tissue in the temporal and nasal regions...
  13. ncbi request reprint Improved signal-to-noise ratio in spectral-domain compared with time-domain optical coherence tomography
    Johannes F de Boer
    Harvard Medical School and Wellman Center for Photomedicine, Massachusetts General Hospital, 50 Blossom Street, BAR 724, Boston, Massachusetts 02114, USA
    Opt Lett 28:2067-9. 2003
    ..A significant SNR gain of several hundredfold is found for acquisition in the spectral domain. The SNR benefit is demonstrated experimentally in a hybrid time-domain-spectral-domain OCT system...
  14. ncbi request reprint Imaging the mucosa of the human vocal fold with optical coherence tomography
    James A Burns
    Department of Surgery, Harvard Medical School, Boston, MA 02114, USA
    Ann Otol Rhinol Laryngol 114:671-6. 2005
    ..Optical coherence tomography (OCT), a noncontact, noninvasive technology that provides cross-sectional images by means of backscattered light, offers the potential for delineating these layers in vivo...
  15. pmc Optical contrast agents and imaging systems for detection and diagnosis of cancer
    Mark C Pierce
    Department of Bioengineering, Rice University, Houston, TX, USA
    Int J Cancer 123:1979-90. 2008
    ..In this article, we review fundamental techniques and recent developments in optical molecular imaging, emphasizing laboratory and clinical systems that aim to visualize the microscopic and macroscopic hallmarks of cancer...