Homer H Pien

Summary

Affiliation: Harvard University
Country: USA

Publications

  1. ncbi request reprint Using imaging biomarkers to accelerate drug development and clinical trials
    Homer H Pien
    Department of Radiology, Massachusetts General Hospital, 55 Fruit Street, Boston, MA 02114, USA
    Drug Discov Today 10:259-66. 2005
  2. doi request reprint Adaptive statistical iterative reconstruction technique for radiation dose reduction in chest CT: a pilot study
    Sarabjeet Singh
    Department of Radiology, Massachusetts General Hospital, 25 New Chardon St, 4th Floor, 467C, Boston, MA 02114, USA
    Radiology 259:565-73. 2011
  3. ncbi request reprint Imaging angiogenesis: applications and potential for drug development
    Janet C Miller
    Department of Radiology, Massachusetts General Hospital, 100 Charles River Plaza, Boston, MA 02114, USA
    J Natl Cancer Inst 97:172-87. 2005
  4. doi request reprint A decomposition-based CT reconstruction formulation for reducing blooming artifacts
    Synho Do
    Department of Radiology, Massachusetts General Hospital, Boston, MA, USA
    Phys Med Biol 56:7109-25. 2011
  5. ncbi request reprint Trends in the use and role of biomarkers in phase I oncology trials
    Bernardo H L Goulart
    Massachusetts General Hospital Cancer Center, Harvard Medical School, Boston, MA, USA
    Clin Cancer Res 13:6719-26. 2007
  6. doi request reprint Abdominal CT: comparison of adaptive statistical iterative and filtered back projection reconstruction techniques
    Sarabjeet Singh
    Department of Radiology, Massachusetts General Hospital, 25 New Chardon St, Suite 400B, Boston, MA 02114, USA
    Radiology 257:373-83. 2010

Detail Information

Publications6

  1. ncbi request reprint Using imaging biomarkers to accelerate drug development and clinical trials
    Homer H Pien
    Department of Radiology, Massachusetts General Hospital, 55 Fruit Street, Boston, MA 02114, USA
    Drug Discov Today 10:259-66. 2005
    ..We conclude with some remarks concerning new developments that will be required to significantly advance the field of pharmaco-imaging...
  2. doi request reprint Adaptive statistical iterative reconstruction technique for radiation dose reduction in chest CT: a pilot study
    Sarabjeet Singh
    Department of Radiology, Massachusetts General Hospital, 25 New Chardon St, 4th Floor, 467C, Boston, MA 02114, USA
    Radiology 259:565-73. 2011
    ....
  3. ncbi request reprint Imaging angiogenesis: applications and potential for drug development
    Janet C Miller
    Department of Radiology, Massachusetts General Hospital, 100 Charles River Plaza, Boston, MA 02114, USA
    J Natl Cancer Inst 97:172-87. 2005
    ..Finally, we discuss which imaging methods are most likely to have the sensitivity and reliability required for monitoring responses to cancer therapy and describe ways in which imaging has been used in clinical trials to date...
  4. doi request reprint A decomposition-based CT reconstruction formulation for reducing blooming artifacts
    Synho Do
    Department of Radiology, Massachusetts General Hospital, Boston, MA, USA
    Phys Med Biol 56:7109-25. 2011
    ..The result is a quantifiable reduction in blooming artifacts without the introduction of new distortions away from the blooming observed in other methods. Results are shown for simulations, phantoms, ex vivo, and in vivo studies...
  5. ncbi request reprint Trends in the use and role of biomarkers in phase I oncology trials
    Bernardo H L Goulart
    Massachusetts General Hospital Cancer Center, Harvard Medical School, Boston, MA, USA
    Clin Cancer Res 13:6719-26. 2007
    ..There has been interest in using biomarkers that aid the evaluation of new anticancer agents. We evaluated trends in the use of biomarkers and their contribution to the main goals of phase I trials...
  6. doi request reprint Abdominal CT: comparison of adaptive statistical iterative and filtered back projection reconstruction techniques
    Sarabjeet Singh
    Department of Radiology, Massachusetts General Hospital, 25 New Chardon St, Suite 400B, Boston, MA 02114, USA
    Radiology 257:373-83. 2010
    ....