D A Petrov

Summary

Affiliation: Harvard University
Country: USA

Publications

  1. ncbi request reprint High intrinsic rate of DNA loss in Drosophila
    D A Petrov
    Department of Organismic and Evolutionary Biology, Harvard University, Cambridge, Massachusetts 02138, USA
    Nature 384:346-9. 1996
  2. ncbi request reprint Trash DNA is what gets thrown away: high rate of DNA loss in Drosophila
    D A Petrov
    Department of Organismic and Evolutionary Biology, Harvard University, Cambridge, MA 02138, USA
    Gene 205:279-89. 1997
  3. ncbi request reprint High rate of DNA loss in the Drosophila melanogaster and Drosophila virilis species groups
    D A Petrov
    Department of Organismic and Evolutionary Biology, Harvard University, Cambridge, Massachusetts, USA
    Mol Biol Evol 15:293-302. 1998
  4. pmc Patterns of nucleotide substitution in Drosophila and mammalian genomes
    D A Petrov
    Harvard University Society of Fellows, 78 Mt Auburn Street, Cambridge, MA 02138, USA
    Proc Natl Acad Sci U S A 96:1475-9. 1999
  5. ncbi request reprint Evidence for DNA loss as a determinant of genome size
    D A Petrov
    Harvard University Society of Fellows, Department of Organismic and Evolutionary Biology, Harvard University, Cambridge, MA 02138, USA
    Science 287:1060-2. 2000
  6. ncbi request reprint Genomic gigantism: DNA loss is slow in mountain grasshoppers
    D Bensasson
    Hartl Lab, Department of Organismic and Evolutionary Biology, Harvard University, Cambridge, MA 02138, USA
    Mol Biol Evol 18:246-53. 2001
  7. ncbi request reprint A combined molecular and cytogenetic approach to genome evolution in Drosophila using large-fragment DNA cloning
    E R Lozovskaya
    Department of Organismic and Evolutionary Biology, Harvard University, Cambridge, MA 02138
    Chromosoma 102:253-66. 1993
  8. ncbi request reprint Genomic regulation of transposable elements in Drosophila
    E R Lozovskaya
    Department of Organismic and Evolutionary Biology, Harvard University, Cambridge, MA 02138, USA
    Curr Opin Genet Dev 5:768-73. 1995

Collaborators

Detail Information

Publications8

  1. ncbi request reprint High intrinsic rate of DNA loss in Drosophila
    D A Petrov
    Department of Organismic and Evolutionary Biology, Harvard University, Cambridge, Massachusetts 02138, USA
    Nature 384:346-9. 1996
    ..This finding has important implications for the study of genome evolution in general and the 'C-value paradox' in particular...
  2. ncbi request reprint Trash DNA is what gets thrown away: high rate of DNA loss in Drosophila
    D A Petrov
    Department of Organismic and Evolutionary Biology, Harvard University, Cambridge, MA 02138, USA
    Gene 205:279-89. 1997
    ..In this paper we outline the theoretical basis of our method, examine the data from this perspective, and discuss potential problems that may bias our estimates...
  3. ncbi request reprint High rate of DNA loss in the Drosophila melanogaster and Drosophila virilis species groups
    D A Petrov
    Department of Organismic and Evolutionary Biology, Harvard University, Cambridge, Massachusetts, USA
    Mol Biol Evol 15:293-302. 1998
    ..virilis group. These results strongly suggest that the high rate of DNA loss is a general feature of Drosophila and not a peculiar property of a particular stretch of DNA in a particular species group...
  4. pmc Patterns of nucleotide substitution in Drosophila and mammalian genomes
    D A Petrov
    Harvard University Society of Fellows, 78 Mt Auburn Street, Cambridge, MA 02138, USA
    Proc Natl Acad Sci U S A 96:1475-9. 1999
    ..C to A.T substitution in mammals, probably because of methylated cytosine "hotspots." When the G.C to A.T substitutions are discounted, the remaining differences are considerably reduced and not statistically significant...
  5. ncbi request reprint Evidence for DNA loss as a determinant of genome size
    D A Petrov
    Harvard University Society of Fellows, Department of Organismic and Evolutionary Biology, Harvard University, Cambridge, MA 02138, USA
    Science 287:1060-2. 2000
    ..Consistent with the hypothesis, DNA loss is more than 40 times slower in Laupala than in Drosophila...
  6. ncbi request reprint Genomic gigantism: DNA loss is slow in mountain grasshoppers
    D Bensasson
    Hartl Lab, Department of Organismic and Evolutionary Biology, Harvard University, Cambridge, MA 02138, USA
    Mol Biol Evol 18:246-53. 2001
    ..The main factor contributing to the difference in the rates of DNA loss estimated for grasshoppers, crickets, and Drosophila appears to be deletion size. Large deletions are relatively rare in Podisma and Italopodisma...
  7. ncbi request reprint A combined molecular and cytogenetic approach to genome evolution in Drosophila using large-fragment DNA cloning
    E R Lozovskaya
    Department of Organismic and Evolutionary Biology, Harvard University, Cambridge, MA 02138
    Chromosoma 102:253-66. 1993
    ..melanogaster. The materials and methods described will make it possible to carry out a direct study of molecular evolution at the level of chromosome structure and organization as well as at the level of individual genes...
  8. ncbi request reprint Genomic regulation of transposable elements in Drosophila
    E R Lozovskaya
    Department of Organismic and Evolutionary Biology, Harvard University, Cambridge, MA 02138, USA
    Curr Opin Genet Dev 5:768-73. 1995
    ..The finding of a type of hybrid dysgenesis in D. virilis, in which multiple unrelated transposable elements are mobilized simultaneously, may also be relevant to host-factor regulation of transposition...