J Manuel Perez

Summary

Affiliation: Harvard University
Country: USA

Publications

  1. doi request reprint Dextran-coated gold nanoparticles for the assessment of antimicrobial susceptibility
    Sudip Nath
    NanoScience Technology Center, Burnett School of Biomedical Sciences, and Department of Chemistry, University of Central Florida, 12424 Research Parkway, Orlando, FL 32826, USA
    Anal Chem 80:1033-8. 2008
  2. ncbi request reprint Viral-induced self-assembly of magnetic nanoparticles allows the detection of viral particles in biological media
    J Manuel Perez
    MGH Center for Molecular Imaging Research, Harvard Medical School, 149 13th Street, Charlestown, Massachusetts 02129, USA
    J Am Chem Soc 125:10192-3. 2003
  3. ncbi request reprint Novel nanosensors for rapid analysis of telomerase activity
    Jan Grimm
    Center for Molecular Imaging Research, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA
    Cancer Res 64:639-43. 2004
  4. ncbi request reprint Use of magnetic nanoparticles as nanosensors to probe for molecular interactions
    J Manuel Perez
    Center for Molecular Imaging Research, Massachusetts General Hospital, Harvard Medical School, Building 149, 13th Street, 5404, Charlestown, MA 02129, USA
    Chembiochem 5:261-4. 2004
  5. ncbi request reprint DNA-based magnetic nanoparticle assembly acts as a magnetic relaxation nanoswitch allowing screening of DNA-cleaving agents
    J Manuel Perez
    MGH Center for Molecular Imaging Research, Harvard Medical School, 149 13th Street, Charlestown, MA 02129, USA
    J Am Chem Soc 124:2856-7. 2002
  6. ncbi request reprint Polymeric nanoparticle preparation that eradicates tumors
    Jason R McCarthy
    MGH Harvard Medical School, Center for Molecular Imaging Research, 149 13th Street, Room 5404, Charlestown, MA 02129, USA
    Nano Lett 5:2552-6. 2005
  7. ncbi request reprint Detection of peroxidase/H2O2-mediated oxidation with enhanced yellow fluorescent protein
    Andrew Tsourkas
    Center for Molecular Imaging Research, Massachusetts General Hospital, Charlestown, Massachusetts 02129, USA
    Anal Chem 77:2862-7. 2005
  8. ncbi request reprint Magnetic relaxation switches capable of sensing molecular interactions
    J Manuel Perez
    Center for Molecular Imaging Research, Massachusetts General Hospital and Harvard Medical School, Boston, MA, 02129
    Nat Biotechnol 20:816-20. 2002
  9. doi request reprint Synthesis of biocompatible dextran-coated nanoceria with pH-dependent antioxidant properties
    J Manuel Perez
    NanoScience Technology Center, Department of Chemistry, and Burnett School of Biomedical Sciences University of Central Florida 12424 Research Parkway, Suite 400 Orlando, FL 32826, USA
    Small 4:552-6. 2008
  10. ncbi request reprint One-step, nanoparticle-mediated bacterial detection with magnetic relaxation
    Charalambos Kaittanis
    NanoScience Technology Center, University of Central Florida, 12424 Research Parkway, Suite 400, Orlando, Florida 32826, USA
    Nano Lett 7:380-3. 2007

Collaborators

Detail Information

Publications11

  1. doi request reprint Dextran-coated gold nanoparticles for the assessment of antimicrobial susceptibility
    Sudip Nath
    NanoScience Technology Center, Burnett School of Biomedical Sciences, and Department of Chemistry, University of Central Florida, 12424 Research Parkway, Orlando, FL 32826, USA
    Anal Chem 80:1033-8. 2008
    ....
  2. ncbi request reprint Viral-induced self-assembly of magnetic nanoparticles allows the detection of viral particles in biological media
    J Manuel Perez
    MGH Center for Molecular Imaging Research, Harvard Medical School, 149 13th Street, Charlestown, Massachusetts 02129, USA
    J Am Chem Soc 125:10192-3. 2003
    ..The applications of this new method span from high-throughput NMR detection of viruses in biological samples to potential MR imaging of viral distribution in vivo...
  3. ncbi request reprint Novel nanosensors for rapid analysis of telomerase activity
    Jan Grimm
    Center for Molecular Imaging Research, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA
    Cancer Res 64:639-43. 2004
    ..Together, these studies establish and validate a novel and powerful tool for rapidly sensing telomerase activity and provide the rationale for developing analogous magnetic nanoparticles for in vivo sensing...
  4. ncbi request reprint Use of magnetic nanoparticles as nanosensors to probe for molecular interactions
    J Manuel Perez
    Center for Molecular Imaging Research, Massachusetts General Hospital, Harvard Medical School, Building 149, 13th Street, 5404, Charlestown, MA 02129, USA
    Chembiochem 5:261-4. 2004
    ..These magnetic nanosensors have been designed to detect specific mRNA, proteins, enzymatic activity, and pathogens (e.g., virus) with sensitivity in the low femtomole range (0.5-30 fmol)...
  5. ncbi request reprint DNA-based magnetic nanoparticle assembly acts as a magnetic relaxation nanoswitch allowing screening of DNA-cleaving agents
    J Manuel Perez
    MGH Center for Molecular Imaging Research, Harvard Medical School, 149 13th Street, Charlestown, MA 02129, USA
    J Am Chem Soc 124:2856-7. 2002
    ..These qualities render the developed nanoparticles and their nanoassemblies as magnetic relaxation switches capable of screening for DNA-cleaving compounds by magnetic resonance methods such as MRI and NMR...
  6. ncbi request reprint Polymeric nanoparticle preparation that eradicates tumors
    Jason R McCarthy
    MGH Harvard Medical School, Center for Molecular Imaging Research, 149 13th Street, Room 5404, Charlestown, MA 02129, USA
    Nano Lett 5:2552-6. 2005
    ..Importantly, in vivo experiments show complete eradication of cancers in mouse models. The concept of photosensitizers with selective phototoxicity should have widespread applications in cancer therapy...
  7. ncbi request reprint Detection of peroxidase/H2O2-mediated oxidation with enhanced yellow fluorescent protein
    Andrew Tsourkas
    Center for Molecular Imaging Research, Massachusetts General Hospital, Charlestown, Massachusetts 02129, USA
    Anal Chem 77:2862-7. 2005
    ..Combined expression of EYFP (quenchable) and ECFP or EGFP (nonquenchable) is expected to allow sensitive monitoring of oxidative stress...
  8. ncbi request reprint Magnetic relaxation switches capable of sensing molecular interactions
    J Manuel Perez
    Center for Molecular Imaging Research, Massachusetts General Hospital and Harvard Medical School, Boston, MA, 02129
    Nat Biotechnol 20:816-20. 2002
    ....
  9. doi request reprint Synthesis of biocompatible dextran-coated nanoceria with pH-dependent antioxidant properties
    J Manuel Perez
    NanoScience Technology Center, Department of Chemistry, and Burnett School of Biomedical Sciences University of Central Florida 12424 Research Parkway, Suite 400 Orlando, FL 32826, USA
    Small 4:552-6. 2008
  10. ncbi request reprint One-step, nanoparticle-mediated bacterial detection with magnetic relaxation
    Charalambos Kaittanis
    NanoScience Technology Center, University of Central Florida, 12424 Research Parkway, Suite 400, Orlando, Florida 32826, USA
    Nano Lett 7:380-3. 2007
    ..The use of the described magnetic nanosensors in the identification and quantification of bacteria in clinical and environmental samples is anticipated...
  11. doi request reprint Iron oxide nanoparticles: hidden talent
    J Manuel Perez
    Nat Nanotechnol 2:535-6. 2007