Martha Pavlakis

Summary

Affiliation: Harvard University
Country: USA

Publications

  1. doi request reprint Pre-emptive kidney transplantation to improve survival in patients with type 1 diabetes and imminent risk of ESRD
    Martha Pavlakis
    Renal Division and the Transplant Institute at Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA
    Semin Nephrol 32:505-11. 2012
  2. doi request reprint The timing of dialysis and kidney transplantation in type 1 diabetes
    M Pavlakis
    Renal Division, The Transplant Institute, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA
    Diabetes Obes Metab 14:689-93. 2012
  3. doi request reprint Live kidney donation: a 36-year-old woman hoping to donate a kidney to her mother
    Martha Pavlakis
    Harvard Medical School, and Beth Israel Deaconess Medical Center, 110 Francis St, Boston, MA 02215, USA
    JAMA 305:592-9. 2011
  4. ncbi request reprint Renal allograft failure predictors after PAK transplantation: results from the New England Collaborative Association of Pancreas Programs
    Martha Pavlakis
    Department of Medicine, Division of Nephrology, The Transplant Institute, Beth Israel Deaconess Medical Center, Boston, MA 02215, USA
    Transplantation 89:1347-53. 2010
  5. ncbi request reprint Resolved: in minimizing kidney transplant immunosuppression, steroids should go before calcineurin inhibitors: con
    Martha Pavlakis
    Kidney Transplantation, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts 02215, USA
    J Am Soc Nephrol 18:3028-30. 2007
  6. ncbi request reprint Pancreas and islet cell transplantation in diabetes
    Martha Pavlakis
    Department of Medicine, Boston, Masachusetts, USA
    Curr Opin Endocrinol Diabetes Obes 14:146-50. 2007
  7. ncbi request reprint Transplantation for type 1 diabetes: whole organ pancreas and islet cells
    Martha Pavlakis
    Beth Israel Deaconess Medical Center, The Transplant Center, 110 Francis Street, 7th Floor, Boston, MA 02215, USA
    Curr Diab Rep 6:473-8. 2006
  8. ncbi request reprint New-onset diabetes after transplantation
    Martha Pavlakis
    Harvard Medical School, Beth Israel Deaconess Medical Center, Boston, MA 02215, USA
    Curr Diab Rep 5:300-4. 2005
  9. ncbi request reprint Mycophenolate mofetil versus sirolimus as an adjunct to calcineurin inhibition after renal transplantation
    Martha Pavlakis
    Medicine at Harvard Medical School, Beth Israel Deaconess Medical Center, Boston, MA 02215, USA
    Nat Clin Pract Nephrol 2:558-9. 2006
  10. doi request reprint Timing of sirolimus conversion influences recovery of renal function in liver transplant recipients
    Christin C Rogers
    Department of Pharmacy, Beth Israel Deaconess Medical Center, Boston, MA, USA
    Clin Transplant 23:887-96. 2009

Detail Information

Publications42

  1. doi request reprint Pre-emptive kidney transplantation to improve survival in patients with type 1 diabetes and imminent risk of ESRD
    Martha Pavlakis
    Renal Division and the Transplant Institute at Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA
    Semin Nephrol 32:505-11. 2012
    ....
  2. doi request reprint The timing of dialysis and kidney transplantation in type 1 diabetes
    M Pavlakis
    Renal Division, The Transplant Institute, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA
    Diabetes Obes Metab 14:689-93. 2012
    ..New data on both the optimal time to initiate dialysis or to pursue transplantation will be reviewed...
  3. doi request reprint Live kidney donation: a 36-year-old woman hoping to donate a kidney to her mother
    Martha Pavlakis
    Harvard Medical School, and Beth Israel Deaconess Medical Center, 110 Francis St, Boston, MA 02215, USA
    JAMA 305:592-9. 2011
    ..Evaluation and eligibility of live kidney donors and their short- and long-term risks are discussed...
  4. ncbi request reprint Renal allograft failure predictors after PAK transplantation: results from the New England Collaborative Association of Pancreas Programs
    Martha Pavlakis
    Department of Medicine, Division of Nephrology, The Transplant Institute, Beth Israel Deaconess Medical Center, Boston, MA 02215, USA
    Transplantation 89:1347-53. 2010
    ..The reasons for kidney allograft failure subsequent to pancreas after kidney (PAK) are multifactorial; therefore, we examined these factors to identify a meaningful risk assessment that could assist in patient selection...
  5. ncbi request reprint Resolved: in minimizing kidney transplant immunosuppression, steroids should go before calcineurin inhibitors: con
    Martha Pavlakis
    Kidney Transplantation, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts 02215, USA
    J Am Soc Nephrol 18:3028-30. 2007
  6. ncbi request reprint Pancreas and islet cell transplantation in diabetes
    Martha Pavlakis
    Department of Medicine, Boston, Masachusetts, USA
    Curr Opin Endocrinol Diabetes Obes 14:146-50. 2007
    ..The following review of the field of whole organ pancreas and islet cell transplantation for type 1 diabetes mellitus is timely and relevant, since new findings and outcomes in both fields have emerged in the recent past...
  7. ncbi request reprint Transplantation for type 1 diabetes: whole organ pancreas and islet cells
    Martha Pavlakis
    Beth Israel Deaconess Medical Center, The Transplant Center, 110 Francis Street, 7th Floor, Boston, MA 02215, USA
    Curr Diab Rep 6:473-8. 2006
    ..Beta-cell transplantation continues to evolve, with considerable improvement in results over the past two decades, and is a cost-effective option for select patients with type 1 diabetes...
  8. ncbi request reprint New-onset diabetes after transplantation
    Martha Pavlakis
    Harvard Medical School, Beth Israel Deaconess Medical Center, Boston, MA 02215, USA
    Curr Diab Rep 5:300-4. 2005
    ..Evaluation of patient risk for post-transplant diabetes mellitus and its complications is an important consideration in initial selection and subsequent modification of the immunosuppressive regimen...
  9. ncbi request reprint Mycophenolate mofetil versus sirolimus as an adjunct to calcineurin inhibition after renal transplantation
    Martha Pavlakis
    Medicine at Harvard Medical School, Beth Israel Deaconess Medical Center, Boston, MA 02215, USA
    Nat Clin Pract Nephrol 2:558-9. 2006
  10. doi request reprint Timing of sirolimus conversion influences recovery of renal function in liver transplant recipients
    Christin C Rogers
    Department of Pharmacy, Beth Israel Deaconess Medical Center, Boston, MA, USA
    Clin Transplant 23:887-96. 2009
    ..The only improvement in the LC group was from conversion to the three-month time point. We conclude that EC to SRL results in a profound improvement in eGFR that begins at three months and is sustained beyond one yr...
  11. doi request reprint Evaluation of native kidney recovery after simultaneous liver-kidney transplantation
    Jean M Francis
    Department of Medicine, Boston University Medical Center, Boston, MA, USA
    Transplantation 93:530-5. 2012
    ..Identifying predictors of native kidney function recovery after SLK requires an accurate measure of the relative function of all three kidneys in patients with SLK...
  12. doi request reprint Outcomes with conversion from calcineurin inhibitors to sirolimus after renal transplantation in the context of steroid withdrawal or steroid continuation
    Ogo I Egbuna
    The Transplant Institute, Beth Israel Deaconess Medical Center, Boston, MA 02215, USA
    Transplantation 88:684-92. 2009
    ..A number of studies have suggested that conversion from calcineurin inhibitors (CNI) to sirolimus (SRL) can improve graft function in renal transplant patients. None of these studies has converted patients to SRL in the absence of steroids...
  13. pmc On the intraoperative molecular status of renal allografts after vascular reperfusion and clinical outcomes
    Yingyos Avihingsanon
    Department of Medicine Beth Israel Deaconess Medical Center, Harvard Medical School, Boston MA, USA
    J Am Soc Nephrol 16:1542-8. 2005
    ..The transcriptional profiling data provide absolutely essential data to the predictive models, particularly with respect to AR and renal function 6 mo posttransplantation...
  14. pmc Gene expression profiling of the donor kidney at the time of transplantation predicts clinical outcomes 2 years after transplantation
    Gabor Bodonyi-Kovacs
    Transplant Institute, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, USA
    Hum Immunol 71:451-5. 2010
    ..This post hoc analysis demonstrates that hypothesis-driven, targeted polymerase chain reaction profiling of gene expression in the donor kidney at the time of engraftment can predict 2-year post-transplantation clinical outcomes...
  15. doi request reprint A cross-sectional study of fatigue and sleep quality before and after kidney transplantation
    James R Rodrigue
    The Transplant Institute, Beth Israel Deaconess Center for Transplant Outcomes and Quality Improvement and Medical Center, Harvard Medical School, Boston, MA 02215, USA
    Clin Transplant 25:E13-21. 2011
    ..Fatigue and sleep disturbances are common before and after KTx, and study findings have important implications for their assessment and management...
  16. pmc Willingness to pursue live-donor kidney transplantation among waitlisted patients infected with human immunodeficiency virus (HIV): a preliminary investigation
    James R Rodrigue
    Center for Transplant Outcomes and Quality Improvement, The Transplant Institute, Beth Israel Deaconess Medical Center and the Harvard Medical School, Boston, MA, USA
    Transplantation 95:787-90. 2013
    ....
  17. ncbi request reprint Intensive care unit extubation does not preclude extrarenal organ recovery from donors after cardiac death
    Scott R Johnson
    Division of Transplant Surgery, Department of Surgery, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA 02215, USA
    Transplantation 80:1244-50. 2005
    ..We have sought to increase the utilization of both renal and extrarenal organs from donors after cardiac death (DCD), including DCD donors with ICU extubation...
  18. doi request reprint Practices and barriers in long-term living kidney donor follow-up: a survey of U.S. transplant centers
    Didier A Mandelbrot
    The Transplant Institute, Beth Israel Deaconess Medical Center, Boston, MA 02215, USA
    Transplantation 88:855-60. 2009
    ....
  19. ncbi request reprint Donor postextubation hypotension and age correlate with outcome after donation after cardiac death transplantation
    Karen J Ho
    Department of Surgery, Beth Israel Deaconess Medical Center, Boston, MA 02215, USA
    Transplantation 85:1588-94. 2008
    ..We hypothesized that donor postextubation parameters, including duration and severity of hemodynamic instability or hypoxia might be a better predictor of subsequent graft function...
  20. ncbi request reprint Gender disparities in the live kidney donor evaluation process
    Kathryn A Tuohy
    Transplant Center, Division of Nephrology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA
    Transplantation 82:1402-7. 2006
    ..Females are live kidney donors more often than males. We examined the pool of potential donors to determine at what point in the donor evaluation process this gender disparity develops...
  21. doi request reprint Social adaptability index predicts kidney transplant outcome: a single-center retrospective analysis
    Jalaj Garg
    Division of Nephrology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA
    Nephrol Dial Transplant 27:1239-45. 2012
    ..It has been used in the past to define populations at higher risk for inferior clinical outcomes. The objective of this retrospective study was to evaluate the association of the SAI with renal transplant outcome...
  22. ncbi request reprint Older living donors provide excellent quality kidneys: a single center experience (older living donors)
    Scott R Johnson
    Division of Transplant Surgery, Department of Surgery, Beth Israel Deaconess Medical Center, Boston, MA 02215, USA
    Clin Transplant 19:600-6. 2005
    ..The role of advanced age live donors remains controversial because of decline in glomerular filtration rate and perceived increased risks of perioperative complications...
  23. doi request reprint Renal transplantation in the setting of early steroid withdrawal: a comparison of rabbit antithymocyte globulin induction dosing in two eras
    Christin C Rogers
    Department of Pharmacy, Beth Israel Deaconess Medical Center, Boston, Mass, USA
    Am J Nephrol 38:397-404. 2013
    ..Modern immunosuppression and rabbit antithymocyte globulin (rATG) have facilitated the success of early steroid withdrawal (ESW) protocols. Little data exist on optimal rATG dosing in ESW protocols...
  24. pmc The "House Calls" trial: a randomized controlled trial to reduce racial disparities in live donor kidney transplantation: rationale and design
    James R Rodrigue
    The Transplant Institute and The Center for Transplant Outcomes and Quality Improvement, Beth Israel Deaconess Medical Center, Boston, MA 02215, USA
    Contemp Clin Trials 33:811-8. 2012
    ..Similar trials have been developed recently to broaden the evaluation of House Calls as an innovative disparity-reducing intervention in kidney transplantation...
  25. ncbi request reprint Trajectories of perceived benefits in living kidney donors: association with donor characteristics and recipient outcomes
    James R Rodrigue
    1 Center for Transplant Outcomes and Quality Improvement, The Transplant Institute, Beth Israel Deaconess Medical Center, Boston, MA 2 Harvard Medical School, Boston, MA 3 Transplant Center, Maine Medical Center, Portland, ME 4 Address correspondence to James R Rodrigue, Ph D, The Transplant Institute, Beth Israel Deaconess Medical Center, 110 Francis Street, 7th Floor, Boston, MA 02215
    Transplantation 97:762-8. 2014
    ..This study sought to identify trajectories of perceived benefit over the first 2 years after donation...
  26. doi request reprint Measuring the expectations of kidney donors: initial psychometric properties of the Living Donation Expectancies Questionnaire
    James R Rodrigue
    The Transplant Center, Beth Israel Deaconess Medical Center, Boston, MA 02215, USA
    Transplantation 85:1230-4. 2008
    ..0001), Personal Growth (P<0.01), Quid Pro Quo (P<0.0001), and Health Consequences (P<0.0001) expectations. The LDEQ has promise in evaluating donor candidates' expectations...
  27. doi request reprint Spotting the owl: surreptitious cytomegalovirus disease in a renal transplant recipient
    Joshua L Tarkan
    Department of Medicine, Beth Israel Deaconess Medical Center, Boston, MA 02215, USA
    Clin Transplant 22:391-5. 2008
    ..Potential pitfalls in making a prompt diagnosis are reviewed. The differential diagnosis of a large oral ulceration in a transplant recipient is broad, but should include CMV infection...
  28. doi request reprint Impact of substance abuse on access to renal transplantation
    Gurprataap S Sandhu
    Division of Nephrology, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA, USA
    Transplantation 91:86-93. 2011
    ..The goal of this project was to evaluate the association between recipient's substance abuse and renal transplant access in patients with end-stage renal disease (ESRD)...
  29. pmc Living donor practices in the United States
    Didier A Mandelbrot
    Transplant Institute, Beth Israel Deaconess Medical Center, Boston, MA 02215, USA
    Adv Chronic Kidney Dis 19:212-9. 2012
    ..In this article, we review the current knowledge about living donor practices in the United States...
  30. ncbi request reprint Spouse caregivers of kidney transplant patients: quality of life and psychosocial outcomes
    James R Rodrigue
    The Transplant Institute, Beth Israel Deaconess Medical Center, Boston, Massachusetts 02215, USA
    Prog Transplant 20:335-42; quiz 343. 2010
    ..Little is known about the quality of life, caregiving strain, and psychosocial functioning of these caregivers...
  31. pmc A psychological intervention to improve quality of life and reduce psychological distress in adults awaiting kidney transplantation
    James R Rodrigue
    Center for Transplant Outcomes and Quality Improvement, The Transplant Institute, Beth Israel Deaconess Medical Center, Boston, MA, USA
    Nephrol Dial Transplant 26:709-15. 2011
    ..Effective psychological interventions to improve functioning in these areas are lacking...
  32. ncbi request reprint Acute crescentic glomerulonephritis in a renal allograft: an unusual complication of fungal infection
    Ogo Egbuna
    Division of Nephrology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA
    Am J Kidney Dis 50:468-70. 2007
  33. ncbi request reprint Donor kidney exchanges
    Francis L Delmonico
    New England Organ Bank, Newton, MA, USA
    Am J Transplant 4:1628-34. 2004
    ..Thus, this approach also increases access to deceased donor kidneys for the remaining candidates on the list...
  34. ncbi request reprint Rupture of an infected liver cyst into the pericardium in a kidney transplant recipient with polycystic kidney disease
    Ogo Egbuna
    Division of Nephrology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA
    Am J Kidney Dis 49:851-3. 2007
    ..We present the case of a renal transplant recipient with an infected dominant polycystic liver cyst that ruptured into the pericardium, leading to tamponade...
  35. ncbi request reprint Expression of protective genes in human renal allografts: a regulatory response to injury associated with graft rejection
    Yingyos Avihingsanon
    Division of Immunology, Department of Medicine, Immunobiology Research Center, Harvard Medical School, Boston, MA 02215, USA
    Transplantation 73:1079-85. 2002
    ..Little is known of the pattern of expression of such protective genes and the implication thereof in clinical transplantation...
  36. ncbi request reprint Determinants of hypofiltration during acute renal allograft rejection
    Alkesh Jani
    Division of Nephrology, Stanford University School of Medicine, Stanford, California, USA
    J Am Soc Nephrol 13:773-8. 2002
    ....
  37. doi request reprint Clinical pathways in transplantation: a review and examples from Beth Israel Deaconess Medical Center
    Martha Pavlakis
    Center for Transplant Outcomes and Quality Improvement, The Transplant Institute, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA 02115, USA
    Clin Transplant 26:382-6. 2012
    ..Our CPs can be found at http://bidmc.org/CentersandDepartments/Departments/TransplantInstitute/TransplantClinicalPathways.aspx...
  38. ncbi request reprint BK virus infection after non-renal transplantation
    Martha Pavlakis
    Beth Israel Deaconess Hospital, Boston, Massachusetts, USA
    Adv Exp Med Biol 577:185-9. 2006
    ..While much of the subsequent research focuses on patients after renal transplantation, we will review PV impact in patients after bone marrow transplant (BMT) and those with non-renal solid organ transplants...
  39. ncbi request reprint Activated intrarenal transcription of CTL-effectors and TGF-beta1 in children with focal segmental glomerulosclerosis
    Juergen Strehlau
    Division of Immunology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, USA
    Kidney Int 61:90-5. 2002
    ..Based on the presence of elevated cytokine levels in peripheral blood, a T cell-induced injury could be postulated...
  40. ncbi request reprint Diabetes after transplantation and sirolimus: what's the connection?
    Martha Pavlakis
    J Am Soc Nephrol 19:1255-6. 2008
  41. ncbi request reprint Do we know enough to mandate donor evaluation testing?
    Martha Pavlakis
    Am J Transplant 8:466. 2008
  42. ncbi request reprint Reproduction and pregnancy in transplant recipients: current practices
    Dianne B McKay
    Scripps Clinic and the Scripps Research Institute, La Jolla, Calif, USA
    Prog Transplant 16:127-32. 2006
    ....