Winston Patrick Kuo
Affiliation: Harvard University
- Microarray profiling reveals the integrated stress response is activated by halofuginone in mammary epithelial cellsYana G Kamberov
Genetics Department, Harvard Medical School, Boston, MA, USA
BMC Res Notes 4:381. 2011..abstract:..
- A potential role for intragenic miRNAs on their hosts' interactomeLudwig Christian G Hinske
Department of Anaesthesiology, Clinic of the University of Munich, Munich, Germany
BMC Genomics 11:533. 2010....
- Comparison of hybridization-based and sequencing-based gene expression technologies on biological replicatesFang Liu
Department of Tumor Biology, Rikshopitalet Radiumhospitalet Medical Center, Montebello, Oslo, Norway
BMC Genomics 8:153. 2007..As part of an ongoing large-scale cross-platform data comparison framework, we report here a comparison based on identical samples between one-dye DNA microarray platforms and MPSS (Massively Parallel Signature Sequencing)...
- Validation of oligoarrays for quantitative exploration of the transcriptomeVigdis Nygaard
Department of Tumor Biology, Institute for Cancer Research, Norwegian Radium Hospital, Montebello, Oslo, Norway
BMC Genomics 9:258. 2008..105. Our aim was to investigate whether the less resource demanding and more widespread oligoarray technique could provide data that were correlated to and had the same absolute scale as those obtained with MPSS and SAGE...
- A sequence-oriented comparison of gene expression measurements across different hybridization-based technologiesWinston Patrick Kuo
Department of Developmental Biology, Harvard School of Dental Medicine, 188 Longwood Ave, Boston, Massachusetts 02115, USA
Nat Biotechnol 24:832-40. 2006..We demonstrate that, after stringent preprocessing, commercial arrays were more consistent than in-house arrays, and by most measures, one-dye platforms were more consistent than two-dye platforms...
- A primer on gene expression and microarrays for machine learning researchersWinston Patrick Kuo
Decision Systems Group, Brigham and Women s Hospital, Harvard Medical School, Boston, MA, USA
J Biomed Inform 37:293-303. 2004..The goal of this article is to familiarize machine learning researchers with data originated from gene expression microarrays...
- Deciphering gene expression profiles generated from DNA microarrays and their applications in oral medicineWinston Patrick Kuo
Department of Oral Medicine, Infection, and Immunity, Harvard School of Dental Medicine, Cambridge, MA 02115, USA
Oral Surg Oral Med Oral Pathol Oral Radiol Endod 97:584-91. 2004....
- Overview of bioinformatics and its application to oral genomicsW P Kuo
Harvard School of Dental Medicine, Department of Oral Medicine, Infection, and Immunity, 188 Longwood Avenue, Boston, MA 02115, USA
Adv Dent Res 17:89-94. 2003..This manuscript reviews the two most commonly used microarray technologies, basic microarray data analysis, and the results from several ongoing oral cancer genomic studies...
- Microarrays and clinical dentistryWinston Patrick Kuo
Department of Oral Medicine, Infection and Immunity, Harvard School of Dental Medicine, Boston, Mass 02115, USA
J Am Dent Assoc 134:456-62. 2003....
- Gene expression profiling by DNA microarrays and its application to dental researchWinston Patrick Kuo
Department of Oral Medicine and Diagnostic Sciences, Harvard School of Dental Medicine, 188 Longwood Avenue, Boston, MA 02115, USA
Oral Oncol 38:650-6. 2002..The technology permits the simultaneous analysis of tens of thousands of genes for the purposes of gene discovery, disease diagnosis. improved drug development, and therapeutics tailored to specific disease processes...
- Analysis of matched mRNA measurements from two different microarray technologiesWinston Patrick Kuo
Children s Hospital Informatics Program and Division of Endocrinology, Department of Medicine, Children s Hospital, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02115, USA
Bioinformatics 18:405-12. 2002..Cross-platform utilization of data from different technologies has the potential to reduce the need to duplicate experiments but requires corresponding measurements to be comparable...
- Classification and identification of genes associated with oral cancer based on gene expression profiles. A preliminary studyWinston Patrick Kuo
N Y State Dent J 69:23-6. 2003..We found 651 genes to be associated with cancer. This article describes a preliminary study of current developments from the Human Genome Project (HGP) and its application to OSCC...
- Peripheral arterial occlusive disease: global gene expression analyses suggest a major role for immune and inflammatory responsesShijun Fu
Institute of Health Sciences, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences and Shanghai Jiao Tong University School of Medicine, Shanghai, PR China
BMC Genomics 9:369. 2008..However, mechanisms underlying the genesis and progression of the disease are far from clear. Genome-wide gene expression profiling of clinical samples may represent an effective approach to gain relevant information...
- DNA microarrays in otolaryngology-head and neck surgeryMark Eliot Whipple
Department of Otolaryngology Head and Neck Surgery, University of Washington School of Medicine, Seattle 98195 6515, USA
Otolaryngol Head Neck Surg 127:196-204. 2002..Our goal was to review the technologies underlying DNA microarrays and to explore their use in otolaryngology-head and neck surgery...
- Angiogenic heterogeneity in head and neck squamous cell carcinoma: biological and therapeutic implicationsRifat Hasina
Department of Pathology, Medicine and Radiation and Cellular Oncology, The University of Chicago, Chicago, IL, USA
Lab Invest 88:342-53. 2008..Finally, they suggest that studies in conjunction with the ongoing clinical trials that explore the correlation between target expression and clinical outcome are warranted...