A Pascual-Leone

Summary

Affiliation: Harvard University
Country: USA

Publications

  1. ncbi Reversal of TMS-induced motor twitch by training is associated with a reduction in excitability of the antagonist muscle
    Viola Giacobbe
    Burke Cornell Medical Research Institute, White Plains, NY, USA
    J Neuroeng Rehabil 8:46. 2011
  2. ncbi Using non-invasive brain stimulation to augment motor training-induced plasticity
    Nadia Bolognini
    Berenson Allen Center for Noninvasive Brain Stimulation, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, USA
    J Neuroeng Rehabil 6:8. 2009
  3. ncbi Transcranial magnetic stimulation and neuroplasticity
    A Pascual-Leone
    Laboratory for Magnetic Brain Stimulation, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA
    Neuropsychologia 37:207-17. 1999
  4. ncbi The plastic human brain cortex
    Alvaro Pascual-Leone
    Center for Non Invasive Brain Stimulation, Department of Neurology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA
    Annu Rev Neurosci 28:377-401. 2005
  5. ncbi [Transcranial magnetic stimulation: the foundation and potential of modulating specific neuronal networks]
    A Pascual-Leone
    Berenson Allen Center for Noninvasive Brain Stimulation, Harvard Medical School and Beth Israel Deaconess Medical Center, Boston, Massachussets 02215, USA
    Rev Neurol 46:S3-10. 2008
  6. ncbi The right brain hypothesis for obesity
    Miguel Alonso-Alonso
    Berenson-Allen Center for Noninvasive Brain Stimulation, Behavioral Neurology Unit, Department of Neurology, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Mass 02215, USA
    JAMA 297:1819-22. 2007
  7. ncbi Characterizing brain cortical plasticity and network dynamics across the age-span in health and disease with TMS-EEG and TMS-fMRI
    Alvaro Pascual-Leone
    Berenson Allen Center for Noninvasive Brain Stimulation, Division of Cognitive Neurology, Department of Neurology, Beth Israel Deaconess Medical Center, Harvard Medical School, 330 Brookline Avenue, Boston, MA 02215, USA
    Brain Topogr 24:302-15. 2011
  8. ncbi Disrupting the brain to guide plasticity and improve behavior
    Alvaro Pascual-Leone
    Department of Neurology, Center for Non Invasive Brain Stimulation, Harvard Medical School and Beth Israel Deaconess Medical Center, Boston, MA 02215, USA
    Prog Brain Res 157:315-329. 2006
  9. ncbi Chronometry of parietal and prefrontal activations in verbal working memory revealed by transcranial magnetic stimulation
    F M Mottaghy
    Department of Neurology, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, 330 Brookline Avenue, Kirstein Building KS 452, Boston, MA 02215, USA
    Neuroimage 18:565-75. 2003
  10. ncbi Intracortical inhibition and facilitation in human facial motor area: difference between upper and lower facial area
    M Kobayashi
    Laboratory for Magnetic Brain Stimulation, Department of Neurology, Beth Israel Deaconess Medical Center, Harvard Medical School, 330 Brookline Avenue KS452, Boston, MA 02215, USA
    Clin Neurophysiol 112:1604-11. 2001

Research Grants

  1. NEURAL PLASTICITY ASSOCIATED WITH BRAILLE LEARNING
    Alvaro Pascual Leone; Fiscal Year: 2006
  2. Study and Modulation of Brain Plasticity
    Alvaro Pascual Leone; Fiscal Year: 2007
  3. Seeing through the Ears
    Alvaro Pascual Leone; Fiscal Year: 2006
  4. Perceptual encoding and imagery in prosopagnosia
    Alvaro Pascual Leone; Fiscal Year: 2005
  5. NEURAL PLASTICITY ASSOCIATED WITH BRAILLE LEARNING
    Alvaro Pascual Leone; Fiscal Year: 2001

Collaborators

Detail Information

Publications132 found, 100 shown here

  1. ncbi Reversal of TMS-induced motor twitch by training is associated with a reduction in excitability of the antagonist muscle
    Viola Giacobbe
    Burke Cornell Medical Research Institute, White Plains, NY, USA
    J Neuroeng Rehabil 8:46. 2011
    ..We investigated; (1) whether this phenomenon might occur for movements at the wrist, and (2) how specific TMS activation patterns of opposing muscles underlie the practice-induced change in direction...
  2. ncbi Using non-invasive brain stimulation to augment motor training-induced plasticity
    Nadia Bolognini
    Berenson Allen Center for Noninvasive Brain Stimulation, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, USA
    J Neuroeng Rehabil 6:8. 2009
    ..In this review we discuss how these techniques can enhance the effects of a behavioural intervention and the clinical evidence to date...
  3. ncbi Transcranial magnetic stimulation and neuroplasticity
    A Pascual-Leone
    Laboratory for Magnetic Brain Stimulation, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA
    Neuropsychologia 37:207-17. 1999
    ....
  4. ncbi The plastic human brain cortex
    Alvaro Pascual-Leone
    Center for Non Invasive Brain Stimulation, Department of Neurology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA
    Annu Rev Neurosci 28:377-401. 2005
    ..The challenge we face is to learn enough about the mechanisms of plasticity to modulate them to achieve the best behavioral outcome for a given subject...
  5. ncbi [Transcranial magnetic stimulation: the foundation and potential of modulating specific neuronal networks]
    A Pascual-Leone
    Berenson Allen Center for Noninvasive Brain Stimulation, Harvard Medical School and Beth Israel Deaconess Medical Center, Boston, Massachussets 02215, USA
    Rev Neurol 46:S3-10. 2008
    ..To offer an introduction to the neurophysiologic technique of transcranial magnetic stimulation (TMS)...
  6. ncbi The right brain hypothesis for obesity
    Miguel Alonso-Alonso
    Berenson-Allen Center for Noninvasive Brain Stimulation, Behavioral Neurology Unit, Department of Neurology, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Mass 02215, USA
    JAMA 297:1819-22. 2007
  7. ncbi Characterizing brain cortical plasticity and network dynamics across the age-span in health and disease with TMS-EEG and TMS-fMRI
    Alvaro Pascual-Leone
    Berenson Allen Center for Noninvasive Brain Stimulation, Division of Cognitive Neurology, Department of Neurology, Beth Israel Deaconess Medical Center, Harvard Medical School, 330 Brookline Avenue, Boston, MA 02215, USA
    Brain Topogr 24:302-15. 2011
    ..Furthermore, aberrant, excessive, insufficient, or mistimed plasticity may represent the proximal pathogenic cause of neurodevelopmental and neurodegenerative disorders such as autism spectrum disorders or Alzheimer's disease...
  8. ncbi Disrupting the brain to guide plasticity and improve behavior
    Alvaro Pascual-Leone
    Department of Neurology, Center for Non Invasive Brain Stimulation, Harvard Medical School and Beth Israel Deaconess Medical Center, Boston, MA 02215, USA
    Prog Brain Res 157:315-329. 2006
    ..Such interventions to guide behavior or treat pathological symptomatology might be more immediate in their behavioral repercussion and thus more effective than approaches intent on addressing underlying genetic predispositions...
  9. ncbi Chronometry of parietal and prefrontal activations in verbal working memory revealed by transcranial magnetic stimulation
    F M Mottaghy
    Department of Neurology, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, 330 Brookline Avenue, Kirstein Building KS 452, Boston, MA 02215, USA
    Neuroimage 18:565-75. 2003
    ..Left- and right-sided brain areas might be involved in parallel processing of semantic and object features of the stimuli, respectively...
  10. ncbi Intracortical inhibition and facilitation in human facial motor area: difference between upper and lower facial area
    M Kobayashi
    Laboratory for Magnetic Brain Stimulation, Department of Neurology, Beth Israel Deaconess Medical Center, Harvard Medical School, 330 Brookline Avenue KS452, Boston, MA 02215, USA
    Clin Neurophysiol 112:1604-11. 2001
    ..CONCLUSION: The bi-hemispheric control of volitional movement and the modulation from brainstem projections appear to markedly influence intracortical inhibitory and excitatory systems in the motor cortical representation of o. oculi...
  11. ncbi Phase-specific modulation of cortical motor output during movement observation
    M Gangitano
    Department of Neurology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA
    Neuroreport 12:1489-92. 2001
    ..The presence of such an effect is consistent with the notion of a mirror neuron system in premotor areas that couples action execution and action observation also in terms of temporal coding...
  12. ncbi Repetitive transcranial magnetic stimulation is as effective as fluoxetine in the treatment of depression in patients with Parkinson's disease
    F Fregni
    Department of Neurology, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachusetts 02215, USA
    J Neurol Neurosurg Psychiatry 75:1171-4. 2004
    ..To study the efficacy of 15 Hz repetitive transcranial magnetic stimulation (rTMS) in treating depression in patients with Parkinson's disease...
  13. ncbi Transcranial magnetic stimulation in cognitive neuroscience--virtual lesion, chronometry, and functional connectivity
    A Pascual-Leone
    Laboratory for Magnetic Brain Stimulation, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA
    Curr Opin Neurobiol 10:232-7. 2000
    ....
  14. ncbi Repetitive TMS of the motor cortex improves ipsilateral sequential simple finger movements
    M Kobayashi
    Laboratory for Magnetic Brain Stimulation, Department of Neurology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA
    Neurology 62:91-8. 2004
    ....
  15. ncbi Release of premotor activity after repetitive transcranial magnetic stimulation of prefrontal cortex
    Massimo Gangitano
    Harvard Medical School, Boston, Massachusetts, USA
    Soc Neurosci 3:289-302. 2008
    ..We hypothesize that the perceptual analysis for action selection within the PFC was modulated by rTMS and its temporary functional inactivation in turn influenced the premotor areas for motor programming...
  16. ncbi Enhanced visual spatial attention ipsilateral to rTMS-induced 'virtual lesions' of human parietal cortex
    C C Hilgetag
    Boston University School of Medicine, Department of Anatomy and Neurobiology, 700 Albany Street W746, Boston, Massachusetts 02118, USA
    Nat Neurosci 4:953-7. 2001
    ..These results underline the potential of focal brain dysfunction to produce behavioral improvement and give experimental support to models of interhemispheric competition in the distributed brain network for spatial attention...
  17. ncbi Effects of single-pulse transcranial magnetic stimulation (TMS) on functional brain activity: a combined event-related TMS and evoked potential study
    G Thut
    Laboratory for Magnetic Brain Stimulation, Beth Israel Deaconess Medical Center, 330 Brookline Avenue, Kirstein Building KS 454, Boston, MA 02215, USA
    Clin Neurophysiol 114:2071-80. 2003
    ..Our data suggest effects of relatively long duration (approximately 100 ms) when TMS is applied while functional neuronal activity evolves...
  18. ncbi Transient tinnitus suppression induced by repetitive transcranial magnetic stimulation and transcranial direct current stimulation
    F Fregni
    Harvard Center for Noninvasive Brain Stimulation, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA
    Eur J Neurol 13:996-1001. 2006
    ..These effects were short lasting. These results replicate the findings of the previous study and, in addition, show preliminary evidence that anodal tDCS of LTA induces a similar transient tinnitus reduction as high-frequency rTMS...
  19. ncbi Dissociable networks for the expectancy and perception of emotional stimuli in the human brain
    Felix Bermpohl
    Center for Non Invasive Brain Stimulation, Department of Neurology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02132, USA
    Neuroimage 30:588-600. 2006
    ..This dissociation may reflect a distinction between anticipatory and perceptive components of emotional stimulus processing...
  20. ncbi Increased variability of paced finger tapping accuracy following repetitive magnetic stimulation of the cerebellum in humans
    H Theoret
    Laboratory for Magnetic Brain Stimulation, Behavioral Neurology Unit, Beth Israel Deaconess Medical Center, Harvard Medical School, 330 Brookline Ave KS 454, Boston MA 02215, USA
    Neurosci Lett 306:29-32. 2001
    ..This method of 'virtual lesions' can expand the study of the role of the cerebellum in motor control and cognition...
  21. ncbi Tactile spatial resolution in blind braille readers
    R W Van Boven
    Department of Neurology, Northwestern University Medical School, Chicago, IL, USA
    Neurology 54:2230-6. 2000
    ..To determine if blind people have heightened tactile spatial acuity...
  22. ncbi Alpha-band electroencephalographic activity over occipital cortex indexes visuospatial attention bias and predicts visual target detection
    Gregor Thut
    Center for Noninvasive Brain Stimulation, Harvard Medical School, and Beth Israel Deaconess Medical Center, Boston, Massachusetts 02215, USA
    J Neurosci 26:9494-502. 2006
    ..They suggest that the momentary direction of attention, predicting spatial biases in imminent visual processing, can be estimated from a lateralization index of posterior alpha-activity...
  23. ncbi Opposite impact on 14C-2-deoxyglucose brain metabolism following patterns of high and low frequency repetitive transcranial magnetic stimulation in the posterior parietal cortex
    Antoni Valero-Cabre
    Laboratory of Cerebral Dynamics, Plasticity and Rehabilitation, Department of Anatomy and Neurobiology, Boston University School of Medicine, Boston, MA 02118, USA
    Exp Brain Res 176:603-15. 2007
    ..The findings are consistent with previous differential electrophysiological and behavioral effects of low and high frequency rTMS patterns and provide support to uses of rTMS in neuromodulation...
  24. ncbi Lateral visual field stimulation reveals extrastriate cortical activation in the contralateral hemisphere: an fMRI study
    Fredric Schiffer
    Department of Psychiatry, Harvard Medical School, and the Developmental Biopsychiatry Research Program, McLean Hospital, 115 Mill Street, Belmont, MA 02478, USA
    Psychiatry Res 131:1-9. 2004
    ..LSTM appears to increase contralateral fMRI activation in striate and extrastriate cortical areas as predicted by earlier studies reporting differential cognitive and/or emotional effects from unilateral sensory or motor stimulation...
  25. ncbi Diminishing risk-taking behavior by modulating activity in the prefrontal cortex: a direct current stimulation study
    Shirley Fecteau
    Berenson Allen Center for Noninvasive Brain Stimulation, Harvard Medical School, Boston, Massachusetts 02215, USA
    J Neurosci 27:12500-5. 2007
    ....
  26. ncbi Time-dependent changes in cortical excitability after prolonged visual deprivation
    Naomi B Pitskel
    Department of Neurology, Berenson Allen Center for Noninvasive Brain Stimulation, Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA
    Neuroreport 18:1703-7. 2007
    ..Thus, light deprivation is characterized by a transient increase in visual cortical excitability, followed by a sustained decrease in visual cortex excitability that quickly returns to baseline levels after re-exposure to light...
  27. ncbi M1 contributes to the intrinsic but not the extrinsic components of motor-skills
    Vincenzo Romei
    Berenson Allen Center for Noninvasive Brain Stimulation, Harvard Medical School and Beth Israel Deaconess Medical Center, Boston, MA, USA
    Cortex 45:1058-64. 2009
    ....
  28. ncbi Age-related differences in movement representation
    S Hutchinson
    Neuroimaging Laboratory, Department of Neurology, Beth Israel Deaconess Medical Center, Boston, Massachusetts 02215, USA
    Neuroimage 17:1720-8. 2002
    ..This study has important implications for functional imaging experiments of neurological disorders in older subjects...
  29. ncbi Effects of antidepressant treatment with rTMS and fluoxetine on brain perfusion in PD
    F Fregni
    Harvard Center for Noninvasive Brain Stimulation, Department of Neurology, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA 02215, USA
    Neurology 66:1629-37. 2006
    ..Although depression is highly prevalent in Parkinson disease (PD), little is known about the neural correlates associated with depression and antidepressant treatment in PD...
  30. ncbi Transcranial magnetic stimulation of primary motor cortex affects mental rotation
    G Ganis
    Department of Psychology, Harvard University and Laboratory for Magnetic Brain Stimulation, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA, USA
    Cereb Cortex 10:175-80. 2000
    ....
  31. ncbi Repetitive TMS temporarily alters brain diffusion
    F M Mottaghy
    Department of Neurology, Beth Israel Deaconess Medical Center, Boston, MA, USA
    Neurology 60:1539-41. 2003
    ..These findings provide a physiologic correlate to the reported behavioral consequences of off-line 1-Hz rTMS and reveal the transitory nature of the effects...
  32. ncbi Left hand advantage in a self-face recognition task
    J P Keenan
    Department of Neurology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA
    Neuropsychologia 37:1421-5. 1999
    ..These results are in agreement with previous research indicating that self-directed awareness is correlated with right prefrontal activity...
  33. ncbi Studies in cognition: the problems solved and created by transcranial magnetic stimulation
    E M Robertson
    Beth Israel Deaconess Medical Center, Boston, MA 02215, USA
    J Cogn Neurosci 15:948-60. 2003
    ..Although TMS can help bridge the gap between psychological models and brain-based arguments of cognitive functions, hypothesis-driven carefully designed experiments that acknowledge the current limitations of TMS are critical...
  34. ncbi Unconscious modulation of motor cortex excitability revealed with transcranial magnetic stimulation
    Hugo Theoret
    Laboratory for Magnetic Brain Stimulation, Beth Israel Deaconess Medical Center, Harvard Medical School, 330 Brookline Avenue, Boston, MA 02215, USA
    Exp Brain Res 155:261-4. 2004
    ..These data confirm previous reports showing specific motor neural responses associated with an unseen visual stimulus and establish TMS as a valuable tool in the study of the neural correlates of consciousness...
  35. ncbi Impaired interhemispheric interactions in patients with major depression
    Sami Bajwa
    Berenson Allen Center for Noninvasive Brain Stimulation, Department of Neurology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA
    J Nerv Ment Dis 196:671-7. 2008
    ..Our findings showing a decreased interhemispheric modulation in patients with major depression are consistent with the notion that mood disorders are associated with slow interhemispheric switching mechanisms...
  36. ncbi Impact of repetitive transcranial magnetic stimulation of the parietal cortex on metabolic brain activity: a 14C-2DG tracing study in the cat
    Antoni Valero-Cabre
    Cerebral Dynamics, Department of Anatomy and Neurobiology, Boston University School of Medicine, Boston, MA 02118, USA
    Exp Brain Res 163:1-12. 2005
    ..Thus, in the anesthetized animal, the impact of rTMS is upon a distributed network of structures connected to the primary site of application...
  37. ncbi Psychopathy and the mirror neuron system: preliminary findings from a non-psychiatric sample
    Shirley Fecteau
    Center for Non Invasive Brain Stimulation, Beth Israel Deaconess Medical Center and Harvard Medical School, 330 Brookline Avenue, Boston, MA 02215, USA
    Psychiatry Res 160:137-44. 2008
    ..These data suggest the existence of a functional link between 'motor empathy' and psychopathy...
  38. ncbi How do we modulate our emotions? Parametric fMRI reveals cortical midline structures as regions specifically involved in the processing of emotional valences
    Alexander Heinzel
    Behavioral Neurology Unit, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston 02215, USA
    Brain Res Cogn Brain Res 25:348-58. 2005
    ..We conclude that the psychological concept of emotional valence may be related to neural processing in cortical midline regions...
  39. ncbi Modulation of steady-state auditory evoked potentials by cerebellar rTMS
    Maria A Pastor
    Center for Noninvasive Brain Stimulation, Department of Neurology, Beth Israel Deaconess Medical Center, Boston, MA 02215, USA
    Exp Brain Res 175:702-9. 2006
    ....
  40. ncbi Reciprocal modulation and attenuation in the prefrontal cortex: an fMRI study on emotional-cognitive interaction
    Georg Northoff
    Laboratory for Magnetic Brain Stimulation, Division of Behavioral Neurology, Department of Neurology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, USA
    Hum Brain Mapp 21:202-12. 2004
    ..Reciprocal modulation and attenuation in medial and lateral prefrontal cortex might constitute the neurophysiologic basis for emotional-cognitive interaction as observed in both healthy and psychiatric subjects...
  41. ncbi Attentional modulation of emotional stimulus processing: an fMRI study using emotional expectancy
    Felix Bermpohl
    Center for Non Invasive Brain Stimulation, Department of Neurology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, USA
    Hum Brain Mapp 27:662-77. 2006
    ..This enhancement effect is not present in neutral pictures and might parallel accentuated subjective feeling states...
  42. ncbi Growing up blind does not change the neural bases of Theory of Mind
    Marina Bedny
    Berenson Allen Center for Noninvasive Brain Stimulation, Harvard Medical School, 330 Brookline Avenue, KS 158, Boston, MA 02215, USA
    Proc Natl Acad Sci U S A 106:11312-7. 2009
    ..We conclude that the development of neural mechanisms for ToM depends on innate factors and on experiences represented at an abstract level, amodally...
  43. ncbi Suppression of ipsilateral motor cortex facilitates motor skill learning
    Masahito Kobayashi
    Behavioral Neurology Unit, Department of Neurology, Berenson Allen Center for Noninvasive Brain Stimulation, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA, USA
    Eur J Neurosci 29:833-6. 2009
    ..This supports the notion of inter-hemispheric competition and provides novel insights that may be applicable to neurorehabilitation...
  44. ncbi Differential effects of low-frequency rTMS at the occipital pole on visual-induced alpha desynchronization and visual-evoked potentials
    G Thut
    Laboratory for Magnetic Brain Stimulation, Beth Israel Deaconess Medical Center, 330 Brookline Avenue, Kirstein Building KS 454, Boston, MA 02215, USA
    Neuroimage 18:334-47. 2003
    ..This is consistent with the idea that alpha desynchronization serves an integrative role through a corticocortical "gating function."..
  45. ncbi The neurocognitive connection between physical activity and eating behaviour
    R J Joseph
    Center for the Study of Nutrition Medicine, Beth Israel Deaconess Medical Center, Boston, MA 02215, USA
    Obes Rev 12:800-12. 2011
    ..Understanding how physical activity and eating behaviours interact on a neurocognitive level may help to maintain a healthy lifestyle in an obesogenic environment...
  46. ncbi Hand response differences in a self-face identification task
    J P Keenan
    Department of Neurology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA
    Neuropsychologia 38:1047-53. 2000
    ..The data suggest that participants are inclined to identify images as their own when the right hemisphere is preferentially accessed...
  47. ncbi Prefrontal cortex: procedural sequence learning and awareness
    E M Robertson
    Laboratory for Magnetic Brain Stimulation, Behavioral Neurology Unit, Beth Israel Deaconess Medical Center, Harvard Medical School, 330 Brookline Avenue, KS 454, 02215, Boston, MA, USA
    Curr Biol 13:R65-7. 2003
    ..A recent study, however, finds activation of the prefrontal cortex during such tasks regardless of awareness. So what is the neurophysiological basis of awareness, and what is the role of the prefrontal cortex in sequence learning?..
  48. ncbi Neuronavigation increases the physiologic and behavioral effects of low-frequency rTMS of primary motor cortex in healthy subjects
    S Bashir
    Berenson Allen Center for Noninvasive Brain Stimulation, Division of Cognitive Neurology, Department of Neurology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA
    Brain Topogr 24:54-64. 2011
    ..Our findings highlight the spatial specificity of inter-hemispheric TMS effects, illustrate the superiority of navigated rTMS for certain applications, and have implications for therapeutic applications of rTMS...
  49. ncbi Transcranial magnetic stimulation: studying the brain-behaviour relationship by induction of 'virtual lesions'
    A Pascual-Leone
    Department of Neurology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02115, USA
    Philos Trans R Soc Lond B Biol Sci 354:1229-38. 1999
    ..TMS can enhance the results of other neuroimaging techniques by establishing the causal link between brain activity and task performance, and by exploring functional brain connectivity...
  50. ncbi Modulation of spinal cord excitability by subthreshold repetitive transcranial magnetic stimulation of the primary motor cortex in humans
    A Valero-Cabre
    Laboratory for Magnetic Brain Stimulation, Department of Neurology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA
    Neuroreport 12:3845-8. 2001
    ..Sham stimulation did not induce any noticeable change in M or H waves. Slow rTMS might facilitate monosynaptic spinal cord reflexes by inhibiting the cortico-spinal projections modulating spinal excitability...
  51. ncbi Fast backprojections from the motion to the primary visual area necessary for visual awareness
    A Pascual-Leone
    Laboratory for Magnetic Brain Stimulation, Beth Israel Deaconess Medical Center, Harvard Medical School, 330 Brookline Avenue, Kirstein Hall KS454, Boston MA 02115, USA
    Science 292:510-2. 2001
    ..We used transcranial magnetic stimulation to probe the timing and function of feedback from human area MT+/V5 to V1 and found its action to be early and critical for awareness of visual motion...
  52. ncbi Effect of low-frequency transcranial magnetic stimulation on an affective go/no-go task in patients with major depression: role of stimulation site and depression severity
    Felix Bermpohl
    Harvard Center for Non Invasive Brain Stimulation, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA
    Psychiatry Res 141:1-13. 2006
    ..Further studies are needed to determine whether the present paradigm could be used to predict antidepressant treatment success or to individualize stimulation parameters according to specific pathology...
  53. ncbi A sham-controlled trial of a 5-day course of repetitive transcranial magnetic stimulation of the unaffected hemisphere in stroke patients
    Felipe Fregni
    Harvard Center for Non Invasive Brain Stimulation, Beth Israel Deaconess Medical Center, Harvard Medical School, 330 Brookline Ave, KS 452, Boston, Massachusetts 02215, USA
    Stroke 37:2115-22. 2006
    ..We therefore conducted a randomized, sham-controlled, phase II trial to evaluate whether five sessions of low-frequency rTMS can increase the magnitude and duration of these effects and whether this approach is safe...
  54. ncbi A controlled clinical trial of cathodal DC polarization in patients with refractory epilepsy
    Felipe Fregni
    Harvard Center for Noninvasive Brain Stimulation and Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, 330 Brookline Avenue, KS 452, Boston, MA 02215, U S A
    Epilepsia 47:335-42. 2006
    ..To study the effects of cathodal DC polarization in patients with refractory epilepsy and malformations of cortical development (MCDs) as indexed by seizure frequency and epileptiform EEG discharges...
  55. ncbi Cumulative sessions of repetitive transcranial magnetic stimulation (rTMS) build up facilitation to subsequent TMS-mediated behavioural disruptions
    Antoni Valero-Cabre
    Laboratory for Cerebral Dynamics, Plasticity and Rehabilitation, Department of Anatomy and Neurobiology, Boston University School of Medicine, Boston, MA 02118, USA
    Eur J Neurosci 27:765-74. 2008
    ..Such a phenomenon allows a behavioural effect of progressively higher magnitude, but equal duration, in response to individual TMS interventions...
  56. ncbi A sham-controlled, phase II trial of transcranial direct current stimulation for the treatment of central pain in traumatic spinal cord injury
    Felipe Fregni
    Harvard Center for Noninvasive Brain Stimulation, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA
    Pain 122:197-209. 2006
    ..We discuss potential mechanisms for pain amelioration after tDCS, such as a secondary modulation of thalamic nuclei activity...
  57. ncbi Noninvasive cortical stimulation with transcranial direct current stimulation in Parkinson's disease
    Felipe Fregni
    Harvard Center for Non Invasive Brain Stimulation, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts 02215, USA
    Mov Disord 21:1693-702. 2006
    ..These results confirm and extend the notion that cortical brain stimulation might improve motor function in patients with PD...
  58. ncbi Hand motor recovery after stroke: tuning the orchestra to improve hand motor function
    Felipe Fregni
    Harvard Center for Noninvasive Brain Stimulation, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA
    Cogn Behav Neurol 19:21-33. 2006
    ..This paper reviews the stroke characteristics that can predict a good recovery and compensations across brain areas that can be implemented after a stroke to accelerate motor function recovery...
  59. ncbi Transcranial direct current stimulation of the prefrontal cortex modulates the desire for specific foods
    Felipe Fregni
    Berenson Allen Center for Noninvasive Brain Stimulation, Beth Israel Deaconess Medical Center, Harvard Medical School, 330 Brookline Avenue KS 454, Boston, MA, 02215, USA
    Appetite 51:34-41. 2008
    ..These changes were not related to mood changes after any type of tDCS treatment. The effects of tDCS on food craving might be related to a modulation of neural circuits associated with reward and decision-making...
  60. ncbi The 'when' pathway of the right parietal lobe
    Lorella Battelli
    Center for Noninvasive Brain Stimulation, Department of Neurology, Beth Israel Deaconess Medical Center, Harvard Medical School, 330 Brookline Avenue, Boston, MA 02215, USA
    Trends Cogn Sci 11:204-10. 2007
    ..We propose that the disruption of this mechanism is the underlying cause of a wide range of seemingly unrelated tasks being impaired in right parietal patients...
  61. ncbi 'Who is the ideal candidate?': decisions and issues relating to visual neuroprosthesis development, patient testing and neuroplasticity
    Lotfi B Merabet
    Department of Neurology, Center for Noninvasive Brain Stimulation, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA
    J Neural Eng 4:S130-5. 2007
    ..Specifically, an understanding of the adaptive and compensatory changes that occur within the brain could assist in guiding the development of post-implantation rehabilitative strategies and optimize behavioral outcomes...
  62. ncbi Recent advances in the treatment of chronic pain with non-invasive brain stimulation techniques
    Felipe Fregni
    Center for Non Invasive Brain Stimulation, Department of Neurology, Harvard Medical School, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston 02115, USA
    Lancet Neurol 6:188-91. 2007
    ..Further trials must determine the optimum parameters of stimulation. After that, confirmatory, larger studies are mandatory...
  63. ncbi Shape conveyed by visual-to-auditory sensory substitution activates the lateral occipital complex
    Amir Amedi
    Berenson Allen Center for Noninvasive Brain Stimulation, Department of Neurology, Beth Israel Deaconess Medical Center, Harvard Medical School, 330 Brookline Ave, Boston, Massachusetts 02115, USA
    Nat Neurosci 10:687-9. 2007
    ..Recognizing objects by their typical sounds or learning to associate specific soundscapes with specific objects do not activate this region. This suggests that LOtv is driven by the presence of shape information...
  64. ncbi Combined activation and deactivation of visual cortex during tactile sensory processing
    Lotfi B Merabet
    Department of Neurology, Beth Israel Deaconess Medical Center, 330 Brookline Avenue, KS 430, Boston, MA 02215, USA
    J Neurophysiol 97:1633-41. 2007
    ....
  65. ncbi A randomized, sham-controlled, proof of principle study of transcranial direct current stimulation for the treatment of pain in fibromyalgia
    Felipe Fregni
    Harvard Medical School, Boston, Massachusetts 02215, USA
    Arthritis Rheum 54:3988-98. 2006
    ....
  66. ncbi A randomized clinical trial of repetitive transcranial magnetic stimulation in patients with refractory epilepsy
    Felipe Fregni
    Center for Non Invasive Brain Stimulation, Beth Israel Medical Center, Harvard Medical School, Boston, MA 02215, USA
    Ann Neurol 60:447-55. 2006
    ..To study the antiepileptic effects of rTMS in patients with refractory epilepsy and malformations of cortical development in a randomized, double-blind, sham-controlled trial...
  67. ncbi Immediate placebo effect in Parkinson's disease--is the subjective relief accompanied by objective improvement?
    Felipe Fregni
    Harvard Center for Noninvasive Brain Stimulation, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Mass, USA
    Eur Neurol 56:222-9. 2006
    ....
  68. ncbi Predictors of antidepressant response in clinical trials of transcranial magnetic stimulation
    Felipe Fregni
    Harvard Center for Noninvasive Brain Stimulation, Beth Israel Medical Center, Harvard Medical School, Boston, MA 02215, USA
    Int J Neuropsychopharmacol 9:641-54. 2006
    ..In conclusion TMS antidepressant therapy in younger and less treatment-resistant patients is associated with better outcome...
  69. ncbi Effects of transcranial direct current stimulation coupled with repetitive electrical stimulation on cortical spreading depression
    Felipe Fregni
    Center for Noninvasive Brain Stimulation, Harvard Medical School and Beth Israel Deaconess Medical Center, 330 Brookline Ave, KS 452, Boston, MA 02215, USA
    Exp Neurol 204:462-6. 2007
    ....
  70. ncbi Homeostatic effects of plasma valproate levels on corticospinal excitability changes induced by 1Hz rTMS in patients with juvenile myoclonic epilepsy
    Felipe Fregni
    Center for Noninvasive Brain Stimulation, Beth Israel Deaconess Medical Center, Harvard Medical School, 330 Brookline Ave, KS 452, Boston, MA 02215, USA
    Clin Neurophysiol 117:1217-27. 2006
    ..Therefore, we aimed to study the effects of 1 Hz rTMS on corticospinal excitability in patients with juvenile myoclonic epilepsy (JME) in two different conditions: low- or high-plasma valproate levels...
  71. ncbi Negative BOLD differentiates visual imagery and perception
    Amir Amedi
    Center for Noninvasive Brain Stimulation, Department of Neurology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts 02115, USA
    Neuron 48:859-72. 2005
    ..quot;..
  72. ncbi Cancellation of visuoparietal lesion-induced spatial neglect
    Bertram R Payne
    Cerebral Dynamics, Department of Anatomy and Neurobiology, Boston University School of Medicine, 700 Albany Street, Boston, MA 02118, USA
    Exp Brain Res 150:395-8. 2003
    ....
  73. ncbi What blindness can tell us about seeing again: merging neuroplasticity and neuroprostheses
    Lotfi B Merabet
    Department of Ophthalmology, Center for Noninvasive Brain Stimulation, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts 02215, USA
    Nat Rev Neurosci 6:71-7. 2005
    ..However, success in developing functional visual prostheses requires an understanding of how to communicate effectively with the visually deprived brain in order to merge what is perceived visually with what is generated electrically...
  74. ncbi Behavioral and neuroplastic changes in the blind: evidence for functionally relevant cross-modal interactions
    Hugo Theoret
    Laboratory for Magnetic Brain Stimulation, Department of Neurology, Beth Israel Deaconess Medical Center, Harvard Medical School, 330 Brookline Avenue, Boston, MA 02215, USA
    J Physiol Paris 98:221-33. 2004
    ..These issues have important implications for the development of visual prosthesis aimed at restoring some degree of vision in the blind...
  75. ncbi The 'when' parietal pathway explored by lesion studies
    Lorella Battelli
    Department of Neurology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA
    Curr Opin Neurobiol 18:120-6. 2008
    ..Here we show that the when pathway is distinct from and interacts with the well-established 'where' and 'what' pathways...
  76. ncbi Repetitive transcranial magnetic stimulation in the treatment of epilepsia partialis continua
    Alexander Rotenberg
    Department of Neurology, Children s Hospital, Harvard Medical School, Boston, MA 02115, USA
    Epilepsy Behav 14:253-7. 2009
    ..Here, we describe our recent experience with rTMS in the treatment of EPC, as an early step toward evaluating the safety and efficacy of rTMS in the treatment of intractable ongoing focal seizures...
  77. ncbi Awareness modifies the skill-learning benefits of sleep
    Edwin M Robertson
    Laboratory for Magnetic Brain Stimulation, Behavioral Neurology Unit, Beth Israel Deaconess Medical Center, 330 Brookline Avenue, Boston, MA 02215, USA
    Curr Biol 14:208-12. 2004
    ..These results show a behavioral dissociation, based upon an individual's awareness for having learned a sequence of finger movements. Offline learning is sleep dependent for explicit skills but time dependent for implicit skills...
  78. ncbi Repetitive transcranial magnetic stimulation of human area MT/V5 disrupts perception and storage of the motion aftereffect
    Hugo Theoret
    Laboratory for Magnetic Brain Stimulation, Beth Israel Deaconess Medical Center, Harvard Medical School, 330 Brookline Avenue, KS 454, Boston, MA 02215, USA
    Neuropsychologia 40:2280-7. 2002
    ..These data provide experimental support for the notion that MT/V5 subserves perception and storage of the motion aftereffect...
  79. ncbi Paired-pulse transcranial magnetic stimulation: effects of hemispheric laterality, gender, and handedness in normal controls
    Seth D Cahn
    Laboratory for Magnetic Brain Stimulation, Behavioral Neurology, Neurology Department, Beth Israel Deaconess Medical Center, Boston, Massachusetts 02215, USA
    J Clin Neurophysiol 20:371-4. 2003
    ....
  80. ncbi Functional recruitment of visual cortex for sound encoded object identification in the blind
    Lotfi B Merabet
    Department of Neurology, Berenson Allen Center for Noninvasive Brain Stimulation, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA
    Neuroreport 20:132-8. 2009
    ....
  81. ncbi Transcranial magnetic stimulation as an investigative tool in the study of visual function
    Lotfi B Merabet
    Laboratory for Magnetic Brain Stimulation, Department of Neurology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, USA
    Optom Vis Sci 80:356-68. 2003
    ..The application of TMS in the diagnosis as well as possible therapeutic use in various visual disorders is also discussed...
  82. ncbi Baseline cortical excitability determines whether TMS disrupts or facilitates behavior
    Juha Silvanto
    Berenson Allen Center for Noninvasive Brain Stimulation, Harvard Medical School and Beth Israel Deaconess Medical Center, 330 Brookline Avenue, Boston, MA 02215, USA
    J Neurophysiol 99:2725-30. 2008
    ..Our findings provide further evidence for the view that the effects of TMS are modulated by the initial activation state of the targeted neural population...
  83. ncbi Cortical stimulation of the prefrontal cortex with transcranial direct current stimulation reduces cue-provoked smoking craving: a randomized, sham-controlled study
    Felipe Fregni
    Berenson Allen Center for Noninvasive Brain Stimulation, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Mass 02215, USA
    J Clin Psychiatry 69:32-40. 2008
    ....
  84. ncbi Transcranial direct current stimulation of the unaffected hemisphere in stroke patients
    Felipe Fregni
    Harvard Center for Noninvasive Brain Stimulation, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts 02215, USA
    Neuroreport 16:1551-5. 2005
    ..These results suggest that the appropriate modulation of bihemispheric brain structures can promote motor function recovery...
  85. ncbi Off-line learning and the primary motor cortex
    Edwin M Robertson
    Center for Non Invasive Brain Stimulation, Beth Israel Deaconess Medical Center, Boston, Massachusetts 02215, USA
    J Neurosci 25:6372-8. 2005
    ..Off-line improvements of similar magnitude are not supported by similar mechanisms; instead, the mechanisms engaged may depend on brain state...
  86. ncbi Transcranial magnetic stimulation treatment for epilepsy: can it also improve depression and vice versa?
    Felipe Fregni
    Department of Neurology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, USA
    Epilepsy Behav 7:182-9. 2005
    ..This article reviews these data and explores further the question of whether depression and epilepsy can be simultaneously treated with TMS for optimal therapeutic impact...
  87. ncbi Anodal transcranial direct current stimulation of prefrontal cortex enhances working memory
    Felipe Fregni
    Harvard Center for Non Invasive Brain Stimulation, Beth Israel Deaconess Medical Center, Harvard Medical School, 330, Brookline Avenue, KS 452, Boston, MA 02215, USA
    Exp Brain Res 166:23-30. 2005
    ..Furthermore, this effect depends on the stimulation polarity and is specific to the site of stimulation. This result may be helpful to develop future interventions aiming at clinical benefits...
  88. ncbi Transient suppression of seizures by repetitive transcranial magnetic stimulation in a case of Rasmussen's encephalitis
    Alexander Rotenberg
    Division of Epilepsy and Clinical Neurophysiology, Children s Hospital, Harvard Medical School, Boston, MA 02115, USA
    Epilepsy Behav 13:260-2. 2008
    ..Thus, we present this case to illustrate a potential utility of combined continuous EEG recording and rTMS in seizure treatment...
  89. ncbi Antiepileptic effects of repetitive transcranial magnetic stimulation in patients with cortical malformations: an EEG and clinical study
    Felipe Fregni
    Center for Noninvasive Brain Stimulation, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA
    Stereotact Funct Neurosurg 83:57-62. 2005
    ..To study the effects of repetitive transcranial magnetic stimulation (rTMS) on epileptic EEG discharges in patients with refractory epilepsy and malformations of cortical development (MCDs)...
  90. ncbi The time course of off-line motor sequence learning
    Daniel Z Press
    Behavioral Neurology Unit and Center for Non Invasive Brain Stimulation, Department of Neurology, Beth Israel Deaconess Medical Center, Boston, MA 02215, USA
    Brain Res Cogn Brain Res 25:375-8. 2005
    ..Only those re-tested 4 h or 12 h after initial testing showed off-line improvements. This demonstrates that implicitly acquired skills can increase between sessions and the process occurs over hours...
  91. ncbi Lasting accelerative effects of 1 Hz and 20 Hz electrical stimulation on cortical spreading depression: relevance for clinical applications of brain stimulation
    Felipe Fregni
    Harvard Center for Non invasive Brain Stimulation and Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, USA
    Eur J Neurosci 21:2278-84. 2005
    ..Furthermore, the effects are found to be long lasting. We believe that these findings have strong relevance to support the clinical application of therapies involving electrical stimulation for diseases of reduced cortical excitability...
  92. ncbi Transcranial magnetic stimulation for the treatment of depression in neurologic disorders
    Felipe Fregni
    Beth Israel Deaconess Medical Center, Harvard Medical School, 330 Brookline Avenue, KS 452, Boston, MA 02215, USA
    Curr Psychiatry Rep 7:381-90. 2005
    ..Lastly, a framework that includes the parameters of stimulation (intensity, frequency, number of pulses, and site of stimulation) for the treatment of depression in neurologic diseases is proposed...
  93. ncbi Concepts are more than percepts: the case of action verbs
    Marina Bedny
    Berenson Allen Center for Noninvasive Brain Stimulation, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts 02215, USA
    J Neurosci 28:11347-53. 2008
    ..We conclude that concepts are abstracted away from sensory-motor experience and organized according to conceptual properties...
  94. ncbi Seizure suppression by EEG-guided repetitive transcranial magnetic stimulation in the rat
    Alexander Rotenberg
    Department of Neurology, Children s Hospital, Harvard Medical School, 300 Longwood Avenue Fegan 9, Boston, MA 02115, USA
    Clin Neurophysiol 119:2697-702. 2008
    ..To test the anticonvulsive potential of a range of repetitive transcranial magnetic stimulation (rTMS) frequencies by novel methods for simultaneous EEG and rTMS in a rat seizure model...
  95. ncbi Approaches to rehabilitation for visual field defects following brain lesions
    Ela B Plow
    Berenson Allen Center for Noninvasive Brain Stimulation, Department of Neurology, Beth Israel Deaconess Medical Center, Harvard Medical School, 330 Brookline Avenue, KS 158, Boston, MA, USA
    Expert Rev Med Devices 6:291-305. 2009
    ..Novel techniques, aimed at enhancing the effect of these rehabilitative strategies, are also discussed...
  96. ncbi The role of the parietal lobe in visual extinction studied with transcranial magnetic stimulation
    Lorella Battelli
    Harvard Medical School Berenson Allen Center for Nonvasive Brain Stimulation, Department of Neurology, Boston, MA
    J Cogn Neurosci 21:1946-55. 2009
    ..Our results provide a neuronal basis for visual extinction in patients with parietal lobe damage...
  97. ncbi The role of area 17 in visual imagery: convergent evidence from PET and rTMS
    S M Kosslyn
    Department of Psychology, Harvard University, Cambridge, MA 02138, USA
    Science 284:167-70. 1999
    ..In sum, the PET results showed that when patterns of stripes are visualized, Area 17 is activated, and the rTMS results showed that such activation underlies information processing...
  98. ncbi A sham stimulation-controlled trial of rTMS of the unaffected hemisphere in stroke patients
    C G Mansur
    Harvard Center for Non-invasive Brain Stimulation, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA
    Neurology 64:1802-4. 2005
    ..Patients showed a significant decrease in simple and choice reaction time and improved performance of the Purdue Pegboard test with their affected hand after rTMS of the motor cortex in the intact hemisphere as compared with sham rTMS...
  99. ncbi Non-invasive brain stimulation for Parkinson's disease: a systematic review and meta-analysis of the literature
    F Fregni
    Harvard Center for Noninvasive Brain Stimulation, Harvard Medical School and Beth Israel Deaconess Medical Center, Boston, MA, USA
    J Neurol Neurosurg Psychiatry 76:1614-23. 2005
    ..TMS, across applied stimulation sites and parameters, can exert a significant, albeit modest, positive effect on the motor function of patients with PD. ECT also may exert a significant effect on motor function in PD patients...
  100. ncbi Visual phosphene perception modulated by subthreshold crossmodal sensory stimulation
    Ciro Ramos Estebanez
    Berenson Allen Center for Noninvasive Brain Stimulation, Department of Neurology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts 02115, USA
    J Neurosci 27:4178-81. 2007
    ..These interactions may reflect an underlying anatomical connectivity and become further enhanced by attention modulation mechanisms...
  101. ncbi Technology insight: noninvasive brain stimulation in neurology-perspectives on the therapeutic potential of rTMS and tDCS
    Felipe Fregni
    Harvard Medical School and the Beth Israel Deaconess Medical Center, Boston, MA 02215, USA
    Nat Clin Pract Neurol 3:383-93. 2007
    ..We review randomized controlled studies, in focal epilepsy, Parkinson's disease, recovery from stroke, and chronic pain, to illustrate these principles, and we present evidence for the clinical effects of these two techniques...

Research Grants15

  1. NEURAL PLASTICITY ASSOCIATED WITH BRAILLE LEARNING
    Alvaro Pascual Leone; Fiscal Year: 2006
    ..abstract_text> ..
  2. Study and Modulation of Brain Plasticity
    Alvaro Pascual Leone; Fiscal Year: 2007
    ..abstract_text> ..
  3. Seeing through the Ears
    Alvaro Pascual Leone; Fiscal Year: 2006
    ..research grant ..
  4. Perceptual encoding and imagery in prosopagnosia
    Alvaro Pascual Leone; Fiscal Year: 2005
    ..From our prior work, we hypothesize that covert or unconscious recognition is the residual product of a partially damaged face network in the brain. We propose a functional imaging experiment to test this hypothesis. ..
  5. NEURAL PLASTICITY ASSOCIATED WITH BRAILLE LEARNING
    Alvaro Pascual Leone; Fiscal Year: 2001
    ....