C A Paronis
Affiliation: Harvard University
- Evaluation of the reinforcing effects of monoamine reuptake inhibitors under a concurrent schedule of food and i.v. drug delivery in rhesus monkeysMaciej Gasior
McLean Hospital, Harvard Medical School, Belmont, MA 02478, USA
Neuropsychopharmacology 30:758-64. 2005..The absence of reinforcing effects of atomoxetine support the view that, like desipramine, it has no evident abuse potential...
- Apparent pA2 values of benzodiazepine antagonists and partial agonists in monkeysC A Paronis
Harvard Medical School, Behavioral Pharmacology Program, McLean Hospital, Belmont, Massachusetts, USA
J Pharmacol Exp Ther 290:1222-9. 1999..These results further demonstrate that some benzodiazepine-site ligands, e. g., bretazenil and Ro 42-8773, may function as both agonists and as competitive antagonists in vivo...
- Modulating GABA modulatorsCarol A Paronis
McLean Hospital, Harvard Medical School, Belmont, MA, USA
Br J Pharmacol 147:237-8. 2006..These studies raise interesting questions regarding the nature of the interaction between the benzodiazepine and neurosteroid binding sites on GABAA receptors...
- Effects of cocaine under concurrent fixed ratio schedules of food and IV drug availability: a novel choice procedure in monkeysCarol A Paronis
Preclinical Pharmacology Laboratory ADARC, McLean Hospital, 115 Mill Street, Belmont, MA 02478, USA
Psychopharmacology (Berl) 163:283-91. 2002..The relative reinforcing strength of cocaine can be characterized by the distribution of operant behavior during the availability of other reinforcing stimuli...
- Different types of GABA(A) receptors may mediate the anticonflict and response rate-decreasing effects of zaleplon, zolpidem, and midazolam in squirrel monkeysC A Paronis
Harvard Medical School, McLean Hospital, 115 Mill Street, Belmont, MA 02478, USA
Psychopharmacology (Berl) 156:461-8. 2001..The role of different types of GABA(A) receptors in mediating anticonflict and response rate-decreasing effects of benzodiazepines in primate species is not known...
- Modification by dopaminergic drugs of choice behavior under concurrent schedules of intravenous saline and food delivery in monkeysMaciej Gasior
Behaviroal Pharmacology Laboratory Alcohol and Drug Abuse Research Center, McLean Hospital, Belmont, Massachusetts 02478, USA
J Pharmacol Exp Ther 308:249-59. 2004..v. self-administration behavior engendered by priming doses of cocaine may involve actions mediated through both D1 and D2 families of dopamine receptors...
- Evaluation of cannabinoid agonists using punished responding and midazolam discrimination procedures in squirrel monkeysMarcus S Delatte
McLean Hospital Harvard Medical School, Preclinical Pharmacology Laboratory and the ADARC, 115 Mill Street, Belmont, MA 02478, USA
Psychopharmacology (Berl) 198:521-8. 2008..Clinical studies have suggested that marijuana and nabilone have anxiolytic effects in humans, yet studies of anxiolytic-like effects of cannabinoid agonists in mice and rats have yielded mixed results...
- Some effects of CB1 antagonists with inverse agonist and neutral biochemical propertiesJack Bergman
McLean Hospital Harvard Medical School Belmont MA USA
Physiol Behav 93:666-70. 2008..Further studies with AM4113 and other novel CB1 antagonists differing in efficacy should amplify our understanding of the relationship between the pharmacological activity of CB1 antagonists and their behavioral effects...
- Measuring the reinforcing strength of abused drugsJack Bergman
McLean Hospital Harvard Medical School, 115 Mill Street, Belmont, MA 02478, USA
Mol Interv 6:273-83. 2006....
- Behavioral effects of the R-(+)- and S-(-)-enantiomers of the dopamine D(1)-like partial receptor agonist SKF 83959 in monkeysRajeev I Desai
McLean Hospital Harvard Medical School, Belmont, MA 02478, USA
Eur J Pharmacol 558:98-106. 2007..In addition, the inactivity of MCL 201, the S-(-)-enantiomer, suggests that the behavioral effects of SKF 83959 can be attributed primarily to the activity of its R-(+)-enantiomer...