Mark A Parker

Summary

Affiliation: Harvard University
Country: USA

Publications

  1. pmc Neural stem cells injected into the sound-damaged cochlea migrate throughout the cochlea and express markers of hair cells, supporting cells, and spiral ganglion cells
    Mark A Parker
    Department of Communication Sciences and Disorders, Emerson College, Boston, MA 02114, USA
    Hear Res 232:29-43. 2007
  2. pmc Biotechnology in the treatment of sensorineural hearing loss: foundations and future of hair cell regeneration
    Mark A Parker
    Emerson College, Boston, MA, USA
    J Speech Lang Hear Res 54:1709-31. 2011
  3. pmc TAK1 expression in the cochlea: a specific marker for adult supporting cells
    Mark A Parker
    Department of Communication Sciences and Disorders, Emerson College, Boston, MA, USA
    J Assoc Res Otolaryngol 12:471-83. 2011
  4. ncbi request reprint Expression profile of an operationally-defined neural stem cell clone
    Mark A Parker
    Department of Otolaryngology, EN41, Children s Hospital Boston, 300 Longwood Avenue, Boston, MA 02115, USA
    Exp Neurol 194:320-32. 2005
  5. ncbi request reprint Regeneration and replacement in the vertebrate inner ear
    Jonathan I Matsui
    Laboratory for Cellular and Molecular Hearing Research, Department of Otolaryngology, Children s Hospital, Boston, MA 02115, USA
    Drug Discov Today 10:1307-12. 2005
  6. ncbi request reprint The potential use of stem cells for cochlear repair
    Mark A Parker
    Department of Otology and Laryngology, Harvard Medical School, Boston, Mass, USA
    Audiol Neurootol 9:72-80. 2004
  7. ncbi request reprint Cell contact-dependent mechanisms specify taste bud pattern during a critical period early in embryonic development
    Mark A Parker
    Department of Cell and Developmental Biology and Rocky Mountain Taste and Smell Center, University of Colorado Health Sciences Center, Denver, 80262, USA
    Dev Dyn 230:630-42. 2004

Detail Information

Publications8

  1. pmc Neural stem cells injected into the sound-damaged cochlea migrate throughout the cochlea and express markers of hair cells, supporting cells, and spiral ganglion cells
    Mark A Parker
    Department of Communication Sciences and Disorders, Emerson College, Boston, MA 02114, USA
    Hear Res 232:29-43. 2007
    ..Moreover, they suggest that cells of this neural stem cell line may derive some information needed from the microenvironment of the cochlea to differentiate into replacement cells in the cochlea...
  2. pmc Biotechnology in the treatment of sensorineural hearing loss: foundations and future of hair cell regeneration
    Mark A Parker
    Emerson College, Boston, MA, USA
    J Speech Lang Hear Res 54:1709-31. 2011
    ..Next, the author presents a review of stem cell and gene therapy and provides a critical appraisal of their application to hair cell regeneration. The methodologies used in these approaches are highlighted...
  3. pmc TAK1 expression in the cochlea: a specific marker for adult supporting cells
    Mark A Parker
    Department of Communication Sciences and Disorders, Emerson College, Boston, MA, USA
    J Assoc Res Otolaryngol 12:471-83. 2011
    ..While the role of TAK1 in the inner ear is unclear, TAK1 expression may be used as a novel marker for specific sub-populations of supporting cells...
  4. ncbi request reprint Expression profile of an operationally-defined neural stem cell clone
    Mark A Parker
    Department of Otolaryngology, EN41, Children s Hospital Boston, 300 Longwood Avenue, Boston, MA 02115, USA
    Exp Neurol 194:320-32. 2005
    ..Furthermore, when operational definitions are employed, a common set of stem-like genes does emerge across both embryonic and somatic stem cells of various organ systems, including the nervous system...
  5. ncbi request reprint Regeneration and replacement in the vertebrate inner ear
    Jonathan I Matsui
    Laboratory for Cellular and Molecular Hearing Research, Department of Otolaryngology, Children s Hospital, Boston, MA 02115, USA
    Drug Discov Today 10:1307-12. 2005
    ..Current research efforts are focusing on gene manipulation, gene therapy and stem cell transplantation for repairing or replacing damaged mammalian cochlear hair cells, which could lead to therapies for treating deafness in humans...
  6. ncbi request reprint The potential use of stem cells for cochlear repair
    Mark A Parker
    Department of Otology and Laryngology, Harvard Medical School, Boston, Mass, USA
    Audiol Neurootol 9:72-80. 2004
    ..The potential use of several types of stem cells, including embryonic, neural and hematopoietic stem cells, as agents for cochlear repair is examined...
  7. ncbi request reprint Cell contact-dependent mechanisms specify taste bud pattern during a critical period early in embryonic development
    Mark A Parker
    Department of Cell and Developmental Biology and Rocky Mountain Taste and Smell Center, University of Colorado Health Sciences Center, Denver, 80262, USA
    Dev Dyn 230:630-42. 2004
    ..Furthermore, our findings are consistent with specification of taste buds by means of lateral inhibitory signaling, which we hypothesize results from cell contact-dependent or short-range diffusible signals...