Jennifer K Pai

Summary

Affiliation: Harvard University
Country: USA

Publications

  1. pmc C-reactive protein (CRP) gene polymorphisms, CRP levels, and risk of incident coronary heart disease in two nested case-control studies
    Jennifer K Pai
    Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts, USA
    PLoS ONE 3:e1395. 2008
  2. ncbi request reprint Complement factor H (Y402H) polymorphism and risk of coronary heart disease in US men and women
    Jennifer K Pai
    Department of Epidemiology, Harvard School of Public Health, 677 Huntington Avenue, Kresge 9th Floor, Boston, MA 02115, USA
    Eur Heart J 28:1297-303. 2007
  3. ncbi request reprint Polymorphisms in the CC-chemokine receptor-2 (CCR2) and -5 (CCR5) genes and risk of coronary heart disease among US women
    Jennifer K Pai
    Department of Epidemiology, Harvard School of Public Health, Boston, MA 02115, USA
    Atherosclerosis 186:132-9. 2006
  4. ncbi request reprint Moderate alcohol consumption and lower levels of inflammatory markers in US men and women
    Jennifer K Pai
    Department of Epidemiology, Harvard School of Public Health, Boston, MA 02115, USA
    Atherosclerosis 186:113-20. 2006
  5. ncbi request reprint Single nucleotide polymorphisms at the adiponectin locus and risk of coronary heart disease in men and women
    Tobias Pischon
    Department of Nutrition, Harvard School of Public Health, Boston, Massachusetts, USA
    Obesity (Silver Spring) 15:2051-60. 2007
  6. ncbi request reprint Inflammatory markers and the risk of coronary heart disease in men and women
    Jennifer K Pai
    Department of Epidemiology, Harvard School of Public Health, Boston, MA 02115, USA
    N Engl J Med 351:2599-610. 2004
  7. pmc CRP gene variation and risk of community-acquired pneumonia
    Kenneth J Mukamal
    Department of Medicine, Beth Israel Deaconess Medical Center, Boston, MA 02215, USA
    Respirology 15:160-4. 2010
  8. ncbi request reprint Paraoxonase 1 polymorphisms and risk of myocardial infarction in women and men
    Kenneth J Mukamal
    Department of Medicine, Beth Israel Deaconess Medical Center, 330 Brookline Avenue, Boston, MA 02215, USA
    Circ J 73:1302-7. 2009
  9. ncbi request reprint Peroxisome proliferator-activated receptor-gamma2 P12A polymorphism and risk of coronary heart disease in US men and women
    Tobias Pischon
    Department of Nutrition and Epidemiology, Harvard School of Public Health, Boston, Mass, USA
    Arterioscler Thromb Vasc Biol 25:1654-8. 2005
  10. ncbi request reprint Kidney dysfunction, inflammation, and coronary events: a prospective study
    Eric L Knight
    Channing Laboratory, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA
    J Am Soc Nephrol 15:1897-903. 2004

Detail Information

Publications20

  1. pmc C-reactive protein (CRP) gene polymorphisms, CRP levels, and risk of incident coronary heart disease in two nested case-control studies
    Jennifer K Pai
    Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts, USA
    PLoS ONE 3:e1395. 2008
    ..However, few studies have comprehensively examined six common single-nucleotide polymorphisms (SNPs) in the CRP gene, haplotypes, and plasma CRP levels with risk of coronary heart disease (CHD)...
  2. ncbi request reprint Complement factor H (Y402H) polymorphism and risk of coronary heart disease in US men and women
    Jennifer K Pai
    Department of Epidemiology, Harvard School of Public Health, 677 Huntington Avenue, Kresge 9th Floor, Boston, MA 02115, USA
    Eur Heart J 28:1297-303. 2007
    ..We assessed the association between Y402H and risk of CHD in nested case-control studies among two large prospective cohorts of US male health professionals and female nurses...
  3. ncbi request reprint Polymorphisms in the CC-chemokine receptor-2 (CCR2) and -5 (CCR5) genes and risk of coronary heart disease among US women
    Jennifer K Pai
    Department of Epidemiology, Harvard School of Public Health, Boston, MA 02115, USA
    Atherosclerosis 186:132-9. 2006
    ..Genetic variation in CC-chemokine receptor-2 (CCR2) and -5 (CCR5), and their common haplotypes, acting through inflammatory responses, may affect atherosclerosis and risk of coronary heart disease (CHD)...
  4. ncbi request reprint Moderate alcohol consumption and lower levels of inflammatory markers in US men and women
    Jennifer K Pai
    Department of Epidemiology, Harvard School of Public Health, Boston, MA 02115, USA
    Atherosclerosis 186:113-20. 2006
    ..Moderate alcohol consumption is associated with substantially lower risk of cardiovascular disease (CVD). We assessed the relationship between alcohol intake and inflammatory markers to partially explain this beneficial effect...
  5. ncbi request reprint Single nucleotide polymorphisms at the adiponectin locus and risk of coronary heart disease in men and women
    Tobias Pischon
    Department of Nutrition, Harvard School of Public Health, Boston, Massachusetts, USA
    Obesity (Silver Spring) 15:2051-60. 2007
    ..The objective was to examine the association of 5 common single nucleotide polymorphisms (SNPs) at the adiponectin locus with risk of coronary heart disease (CHD) in men and women...
  6. ncbi request reprint Inflammatory markers and the risk of coronary heart disease in men and women
    Jennifer K Pai
    Department of Epidemiology, Harvard School of Public Health, Boston, MA 02115, USA
    N Engl J Med 351:2599-610. 2004
    ..The value of these inflammatory markers as independent predictors remains controversial...
  7. pmc CRP gene variation and risk of community-acquired pneumonia
    Kenneth J Mukamal
    Department of Medicine, Beth Israel Deaconess Medical Center, Boston, MA 02215, USA
    Respirology 15:160-4. 2010
    ..Whether this variation influences risk of infection, and hence whether CRP has anti-infective activity in humans, is uncertain...
  8. ncbi request reprint Paraoxonase 1 polymorphisms and risk of myocardial infarction in women and men
    Kenneth J Mukamal
    Department of Medicine, Beth Israel Deaconess Medical Center, 330 Brookline Avenue, Boston, MA 02215, USA
    Circ J 73:1302-7. 2009
    ..Previous studies of genetic variants of paraoxonase 1 (PON1) and coronary heart disease (CHD) have been conflicting and the modifying effects of lifestyle factors that affect PON1 activity are uncertain...
  9. ncbi request reprint Peroxisome proliferator-activated receptor-gamma2 P12A polymorphism and risk of coronary heart disease in US men and women
    Tobias Pischon
    Department of Nutrition and Epidemiology, Harvard School of Public Health, Boston, Mass, USA
    Arterioscler Thromb Vasc Biol 25:1654-8. 2005
    ..Studies suggest that the A12 allele is associated with reduced risk of type 2 diabetes; however, data on the risk of coronary heart disease (CHD) are scarce and controversial...
  10. ncbi request reprint Kidney dysfunction, inflammation, and coronary events: a prospective study
    Eric L Knight
    Channing Laboratory, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA
    J Am Soc Nephrol 15:1897-903. 2004
    ..These findings warrant further investigation in other populations...
  11. ncbi request reprint Effects of lymphotoxin-alpha gene and galectin-2 gene polymorphisms on inflammatory biomarkers, cellular adhesion molecules and risk of coronary heart disease
    Folkert W Asselbergs
    Department of Nutrition, Harvard School of Public Health, 665 Huntington Avenue, Boston, MA 02115, U S A
    Clin Sci (Lond) 112:291-8. 2007
    ..05). However, no overall effect was demonstrated between LTA gene polymorphisms and risk of CHD...
  12. pmc Oxidation-specific biomarkers and risk of peripheral artery disease
    Monica L Bertoia
    Department of Medicine, Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA
    J Am Coll Cardiol 61:2169-79. 2013
    ..We examined, as secondary analyses, indirect measures of oxidized lipoproteins, including autoantibodies to malondialdehyde-modified low-density lipoprotein (MDA-LDL) and apolipoprotein B-100 immune complexes (ApoB-IC)...
  13. pmc Haptoglobin genotype is a consistent marker of coronary heart disease risk among individuals with elevated glycosylated hemoglobin
    Leah E Cahill
    Department of Nutrition, Harvard School of Public Health, Boston, Massachusetts
    J Am Coll Cardiol 61:728-37. 2013
    ..This study sought to investigate into the biologically plausible interaction between the common haptoglobin (Hp) polymorphism rs#72294371 and glycosylated hemoglobin (HbA(1c)) on risk of coronary heart disease (CHD)...
  14. pmc Total adiponectin and risk of symptomatic lower extremity peripheral artery disease in men
    Michel M Joosten
    Division of General Medicine and Primary Care, Department of Medicine, Beth Israel Deaconess Medical Center, Boston, MA, USA
    Arterioscler Thromb Vasc Biol 33:1092-7. 2013
    ..Whether similar relationships exist for the development of systemic atherosclerosis, such as peripheral artery disease (PAD), is uncertain. We investigated the association between total adiponectin and risk of lower extremity PAD...
  15. pmc Hemoglobin a1c is associated with increased risk of incident coronary heart disease among apparently healthy, nondiabetic men and women
    Jennifer K Pai
    Department of Epidemiology, Harvard School of Public Health, Boston, MA 02115, USA
    J Am Heart Assoc 2:e000077. 2013
    ..Few studies have examined HbA1c and risk of CHD among women and men without clinically elevated levels or previously diagnosed diabetes...
  16. pmc Long-term alcohol consumption in relation to all-cause and cardiovascular mortality among survivors of myocardial infarction: the Health Professionals Follow-up Study
    Jennifer K Pai
    Channing Laboratory, Department of Medicine, Brigham and Women s Hospital, and Harvard Medical School, Boston, MA, USA
    Eur Heart J 33:1598-605. 2012
    ..The aim of this study was to examine the association between long-term alcohol consumption, alcohol consumption before and after myocardial infarction (MI), and all-cause and cardiovascular mortality among survivors of MI...
  17. pmc Associations between conventional cardiovascular risk factors and risk of peripheral artery disease in men
    Michel M Joosten
    Division of General Medicine and Primary Care, Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, USA
    JAMA 308:1660-7. 2012
    ..Previous studies have examined the associations of individual clinical risk factors with risk of peripheral artery disease (PAD), but the combined effects of these risk factors are largely unknown...
  18. ncbi request reprint Common genetic variation in the ATP-binding cassette transporter A1, plasma lipids, and risk of coronary heart disease
    Majken K Jensen
    Department of Nutrition, Harvard School of Public Health, Boston, MA, United States
    Atherosclerosis 195:e172-80. 2007
    ..Neither the -17C/G SNP nor the 2 the coding polymorphisms were associated with risk of CHD. The -565C/T and the -191G/C variants were inversely associated with risk of CHD among healthy women, without pronounced effects on plasma lipids...
  19. ncbi request reprint Stability of novel plasma markers associated with cardiovascular disease: processing within 36 hours of specimen collection
    Jennifer K Pai
    Department of Epidemiology, Harvard School of Public Health, Boston, MA 02115, USA
    Clin Chem 48:1781-4. 2002
  20. ncbi request reprint Thrombospondin-4 Ala387Pro polymorphism is not associated with vascular function and risk of coronary heart disease in US men and women
    Folkert W Asselbergs
    Thromb Haemost 95:589-90. 2006