Paula Nunes

Summary

Affiliation: Harvard University
Country: USA

Publications

  1. pmc A fluorimetry-based ssYFP secretion assay to monitor vasopressin-induced exocytosis in LLC-PK1 cells expressing aquaporin-2
    Paula Nunes
    Massachusetts General Hospital, Boston, MA 02114, USA
    Am J Physiol Cell Physiol 295:C1476-87. 2008
  2. pmc Calcitonin has a vasopressin-like effect on aquaporin-2 trafficking and urinary concentration
    Richard Bouley
    Massachusetts General Hospital, Center for Systems Biology, Program in Membrane Biology and Division of Nephrology, Simches Research Center, Room 8202, 185 Cambridge Street, Boston, MA 02114, USA
    J Am Soc Nephrol 22:59-72. 2011
  3. pmc Simvastatin enhances aquaporin-2 surface expression and urinary concentration in vasopressin-deficient Brattleboro rats through modulation of Rho GTPase
    Wei Li
    Center for Systems Biology, Program in Membrane Biology, Division of Nephrology, Dept of Medicine, Massachusetts General Hospital, Boston, MA 02114, USA
    Am J Physiol Renal Physiol 301:F309-18. 2011
  4. pmc Heterologous downregulation of vasopressin type 2 receptor is induced by transferrin
    Richard Bouley
    1Nephrology Division, MGH Center for Systems Biology, Program in Membrane Biology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts 02114, USA
    Am J Physiol Renal Physiol 304:F553-64. 2013
  5. pmc Phosphorylation events and the modulation of aquaporin 2 cell surface expression
    Dennis Brown
    MGH Center for Systems Biology, Program in Membrane Biology and Nephrology Division, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts 02114, USA
    Curr Opin Nephrol Hypertens 17:491-8. 2008
  6. pmc Bypassing vasopressin receptor signaling pathways in nephrogenic diabetes insipidus
    Richard Bouley
    Massachusetts General Hospital Center for Systems Biology, Program in Membrane Biology and Nephrology Division, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA
    Semin Nephrol 28:266-78. 2008
  7. pmc Acute hypertonicity alters aquaporin-2 trafficking and induces a MAPK-dependent accumulation at the plasma membrane of renal epithelial cells
    Udo Hasler
    Massachusetts General Hospital Center for Systems Biology, Program in Membrane Biology and Nephrology Division, Massachusetts General Hospital, Boston, Massachusetts 02114 2790, USA
    J Biol Chem 283:26643-61. 2008
  8. pmc Angiotensin II and hypertonicity modulate proximal tubular aquaporin 1 expression
    Richard Bouley
    Center for Systems Biology, Program in Membrane Biology, Nephrology Division, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA
    Am J Physiol Renal Physiol 297:F1575-86. 2009

Detail Information

Publications8

  1. pmc A fluorimetry-based ssYFP secretion assay to monitor vasopressin-induced exocytosis in LLC-PK1 cells expressing aquaporin-2
    Paula Nunes
    Massachusetts General Hospital, Boston, MA 02114, USA
    Am J Physiol Cell Physiol 295:C1476-87. 2008
    ..These results support the idea that, in addition to its role in reducing AQP2 endocytosis, VP increases AQP2 exocytosis...
  2. pmc Calcitonin has a vasopressin-like effect on aquaporin-2 trafficking and urinary concentration
    Richard Bouley
    Massachusetts General Hospital, Center for Systems Biology, Program in Membrane Biology and Division of Nephrology, Simches Research Center, Room 8202, 185 Cambridge Street, Boston, MA 02114, USA
    J Am Soc Nephrol 22:59-72. 2011
    ..This suggests that calcitonin has a potential therapeutic use in nephrogenic diabetes insipidus...
  3. pmc Simvastatin enhances aquaporin-2 surface expression and urinary concentration in vasopressin-deficient Brattleboro rats through modulation of Rho GTPase
    Wei Li
    Center for Systems Biology, Program in Membrane Biology, Division of Nephrology, Dept of Medicine, Massachusetts General Hospital, Boston, MA 02114, USA
    Am J Physiol Renal Physiol 301:F309-18. 2011
    ..Our study provides an alternative mechanism to regulate AQP2 trafficking, bypassing the VP-vasopressin receptor signaling pathway...
  4. pmc Heterologous downregulation of vasopressin type 2 receptor is induced by transferrin
    Richard Bouley
    1Nephrology Division, MGH Center for Systems Biology, Program in Membrane Biology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts 02114, USA
    Am J Physiol Renal Physiol 304:F553-64. 2013
    ..It also provides new insights into urine-concentrating defects observed in rat models of hemochromatosis...
  5. pmc Phosphorylation events and the modulation of aquaporin 2 cell surface expression
    Dennis Brown
    MGH Center for Systems Biology, Program in Membrane Biology and Nephrology Division, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts 02114, USA
    Curr Opin Nephrol Hypertens 17:491-8. 2008
    ....
  6. pmc Bypassing vasopressin receptor signaling pathways in nephrogenic diabetes insipidus
    Richard Bouley
    Massachusetts General Hospital Center for Systems Biology, Program in Membrane Biology and Nephrology Division, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA
    Semin Nephrol 28:266-78. 2008
    ....
  7. pmc Acute hypertonicity alters aquaporin-2 trafficking and induces a MAPK-dependent accumulation at the plasma membrane of renal epithelial cells
    Udo Hasler
    Massachusetts General Hospital Center for Systems Biology, Program in Membrane Biology and Nephrology Division, Massachusetts General Hospital, Boston, Massachusetts 02114 2790, USA
    J Biol Chem 283:26643-61. 2008
    ..This may have important implications on adaptational processes governing transcellular water flux and/or cell survival under extreme conditions of hypertonicity...
  8. pmc Angiotensin II and hypertonicity modulate proximal tubular aquaporin 1 expression
    Richard Bouley
    Center for Systems Biology, Program in Membrane Biology, Nephrology Division, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA
    Am J Physiol Renal Physiol 297:F1575-86. 2009
    ....