V Novak

Summary

Affiliation: Harvard University
Country: USA

Publications

  1. ncbi request reprint Venous cavernoma at 8 Tesla MRI
    Vera Novak
    Department of Medicine Gerontology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA
    Magn Reson Imaging 21:1087-9. 2003
  2. pmc High-resolution ultrahigh-field MRI of stroke
    Vera Novak
    Department of Medicine Gerontology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA
    Magn Reson Imaging 23:539-48. 2005
  3. pmc Multimodal pressure-flow method to assess dynamics of cerebral autoregulation in stroke and hypertension
    Vera Novak
    Division of Gerontology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA
    Biomed Eng Online 3:39. 2004
  4. ncbi request reprint Altered cerebral vasoregulation in hypertension and stroke
    V Novak
    Division of Gerontology, Harvard Medical School, Beth Israel Deaconess Medical Center, Boston, MA 02215, USA
    Neurology 60:1657-63. 2003
  5. ncbi request reprint Intracranial ossifications and microangiopathy at 8 Tesla MRI
    V Novak
    Department of Neurology, The Ohio State University, Columbus, Ohio 43210, USA
    Magn Reson Imaging 19:1133-7. 2001
  6. ncbi request reprint Treatment of painful sensory neuropathy with tiagabine: a pilot study
    V Novak
    Department of Neurology, The Ohio State University, Columbus, USA
    Clin Auton Res 11:357-61. 2001
  7. ncbi request reprint Painful sensory neuropathy: prospective evaluation using skin biopsy
    M I Periquet
    Department of Neurology, The Ohio State University, Columbus 43210, USA
    Neurology 53:1641-7. 1999
  8. pmc Altered control of postural sway following cerebral infarction: a cross-sectional analysis
    B Manor
    Division of Gerontology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA
    Neurology 74:458-64. 2010
  9. ncbi request reprint Ultra high field MRI at 8 Tesla of subacute hemorrhagic stroke
    V Novak
    Department of Neurology, Ohio State University, Columbus 43210, USA
    J Comput Assist Tomogr 25:431-5. 2001
  10. ncbi request reprint Autonomic impairment in painful neuropathy
    V Novak
    Department of Neurology, The Ohio State University, Columbus, OH 43210, USA
    Neurology 56:861-8. 2001

Detail Information

Publications35

  1. ncbi request reprint Venous cavernoma at 8 Tesla MRI
    Vera Novak
    Department of Medicine Gerontology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA
    Magn Reson Imaging 21:1087-9. 2003
    ..Cavernoma was not apparent on routine T(2)-weighted FSE images at 1.5 Tesla MRI. This case report indicates that GE images at 8 Tesla can be useful for evaluation of vascular pathologies and microvasculature...
  2. pmc High-resolution ultrahigh-field MRI of stroke
    Vera Novak
    Department of Medicine Gerontology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA
    Magn Reson Imaging 23:539-48. 2005
    ..Ultrahigh-field MRI at 8 T offers unprecedented resolution for imaging brain structures and microvasculature...
  3. pmc Multimodal pressure-flow method to assess dynamics of cerebral autoregulation in stroke and hypertension
    Vera Novak
    Division of Gerontology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA
    Biomed Eng Online 3:39. 2004
    ..The autoregulatory dynamics are difficult to assess because of the nonstationarity and nonlinearity of the component signals...
  4. ncbi request reprint Altered cerebral vasoregulation in hypertension and stroke
    V Novak
    Division of Gerontology, Harvard Medical School, Beth Israel Deaconess Medical Center, Boston, MA 02215, USA
    Neurology 60:1657-63. 2003
    ..Autoregulation of blood flow that maintains steady perfusion over the range of systemic blood pressure is compromised by stroke...
  5. ncbi request reprint Intracranial ossifications and microangiopathy at 8 Tesla MRI
    V Novak
    Department of Neurology, The Ohio State University, Columbus, Ohio 43210, USA
    Magn Reson Imaging 19:1133-7. 2001
    ..Conclusions: MRI at 8 Tesla improves visualization of microangiopathy, ossifications and iron deposits due to enhanced magnetic susceptibility at ultra high magnetic field...
  6. ncbi request reprint Treatment of painful sensory neuropathy with tiagabine: a pilot study
    V Novak
    Department of Neurology, The Ohio State University, Columbus, USA
    Clin Auton Res 11:357-61. 2001
    ..Higher doses (12-16 mg) were associated with increased number of adverse events. Tiagabine may have potential benefits for treatment of painful neuropathy; however, assessment of its efficacy in a larger study is needed...
  7. ncbi request reprint Painful sensory neuropathy: prospective evaluation using skin biopsy
    M I Periquet
    Department of Neurology, The Ohio State University, Columbus 43210, USA
    Neurology 53:1641-7. 1999
    ..have a peripheral neuropathy? 2) What is the role of skin biopsy in establishing a diagnosis of neuropathy? 3) What conditions are associated with the neuropathy? and 4) What laboratory studies are useful in this patient population?..
  8. pmc Altered control of postural sway following cerebral infarction: a cross-sectional analysis
    B Manor
    Division of Gerontology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA
    Neurology 74:458-64. 2010
    ..We examined dependence upon vision and noninfarcted regional brain tissue volumes for postural control in individuals with right and left hemisphere middle cerebral artery (MCA) infarcts...
  9. ncbi request reprint Ultra high field MRI at 8 Tesla of subacute hemorrhagic stroke
    V Novak
    Department of Neurology, Ohio State University, Columbus 43210, USA
    J Comput Assist Tomogr 25:431-5. 2001
    ..MRI at the ultra high field (UHF) of 8 T offers unprecedented resolution, but its utility for stroke evaluation has not been determined yet...
  10. ncbi request reprint Autonomic impairment in painful neuropathy
    V Novak
    Department of Neurology, The Ohio State University, Columbus, OH 43210, USA
    Neurology 56:861-8. 2001
    ..1) To determine the degree and distribution and quantitate the severity of autonomic impairment in painful neuropathy (PN). 2) To assess the role of autonomic testing in evaluating PN...
  11. pmc The effects of body mass index on cerebral blood flow velocity
    Magdy Selim
    Dept of Neurology, Stroke Division, Beth Israel Deaconess Medical Center, Boston, MA, USA
    Clin Auton Res 18:331-8. 2008
    ..Obesity is a risk factor for cerebrovascular disease. We aimed to determine the effects of high body mass index (BMI) on cerebral blood flow regulation in patients with type-2 diabetes mellitus, hypertension, and stroke...
  12. pmc Cross-correlation of instantaneous phase increments in pressure-flow fluctuations: applications to cerebral autoregulation
    Zhi Chen
    Center for Polymer Studies and Department of Physics, Boston University, Boston, Massachusetts 02215, USA
    Phys Rev E Stat Nonlin Soft Matter Phys 73:031915. 2006
    ....
  13. ncbi request reprint High resolution MRI of the brainstem at 8 T
    P Novak
    Department of Neurology, Ohio State University, Columbus, OH 43210, USA
    J Comput Assist Tomogr 25:242-6. 2001
    ..It is concluded that UHFMRI enables the acquisition of high quality images of the upper brainstem with details approaching that of histologic specimen...
  14. pmc Hypertension and cerebral vasoreactivity: a continuous arterial spin labeling magnetic resonance imaging study
    Ihab Hajjar
    Harvard Medical School, Institute for Aging Research Hebrew SeniorLife, Division of Gerontology, Beth Israel Deaconess Medical Center, Boston, MA 02131, USA
    Hypertension 56:859-64. 2010
    ..Because lower vasoreactivity is associated with poor outcomes, studies of the impact of antihypertensive on vasoreactivity are important...
  15. pmc Nonlinear pressure-flow relationship is able to detect asymmetry of brain blood circulation associated with midline shift
    Kun Hu
    Division of Gerontology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts 02215, USA
    J Neurotrauma 26:227-33. 2009
    ..Moreover, mean pressure-flow phase shift is sensitive to the displacement of midline of the brain, and may potentially serve as a marker of asymmetry of cerebral autoregulation...
  16. pmc White matter hyperintensities and dynamics of postural control
    Vera Novak
    Division of Gerontology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA
    Magn Reson Imaging 27:752-9. 2009
    ..This study evaluated the relationship between WMHs and dynamics of postural control in older adults without history of falls...
  17. pmc Association of blood pressure elevation and nocturnal dipping with brain atrophy, perfusion and functional measures in stroke and nonstroke individuals
    Ihab Hajjar
    Department of Medicine, Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA
    Am J Hypertens 23:17-23. 2010
    ..Although both blood pressure elevation and lower nocturnal dipping increase vascular risk, it is not known whether either or both are also associated with brain atrophy, cerebral perfusion, and functional status...
  18. pmc Physiological complexity and system adaptability: evidence from postural control dynamics of older adults
    Brad Manor
    Division of Gerontology, Beth Israel Deaconess Medical Center, 110 Francis St Suite 1B, Boston, MA 02215, USA
    J Appl Physiol 109:1786-91. 2010
    ..Relatively low baseline complexity may, therefore, indicate control systems that are more vulnerable to cognitive and other stressors...
  19. pmc The rationale and design of the antihypertensives and vascular, endothelial, and cognitive function (AVEC) trial in elderly hypertensives with early cognitive impairment: role of the renin angiotensin system inhibition
    Ihab Hajjar
    Harvard Medical School, Boston, MA, USA
    BMC Geriatr 9:48. 2009
    ....
  20. pmc Cerebral flow velocities during daily activities depend on blood pressure in patients with chronic ischemic infarctions
    Vera Novak
    Division of Gerontology, Beth Israel Deaconess Medical Center, 110 Francis Street, Boston, MA 02215, USA
    Stroke 41:61-6. 2010
    ..Target blood pressure (BP) values for optimal cerebral perfusion after an ischemic stroke are still debated. We sought to examine the relationship between BP and cerebral blood flow velocities (BFVs) during daily activities...
  21. pmc Nonlinear assessment of cerebral autoregulation from spontaneous blood pressure and cerebral blood flow fluctuations
    Kun Hu
    Division of Gerontology, Beth Israel Deaconess Medical Center, Harvard Medical School, 812 Stoneman Bldg, 330 Brookline Avenue, Boston, MA 02115, USA
    Cardiovasc Eng 8:60-71. 2008
    ....
  22. ncbi request reprint The relationship between nighttime dipping in blood pressure and cerebral hemodynamics in nonstroke patients
    Ihab Hajjar
    Beth Israel Deaconess Medical Center, Institute for Aging Research at Hebrew SeniorLife, Boston, MA 02131, USA
    J Clin Hypertens (Greenwich) 9:929-36. 2007
    ..03) were associated with higher daytime BFV and lower CVR (P=.01 for systolic BP; P=.02 for diastolic BP). Inadequate nocturnal BP dipping is associated with lower daytime cerebral blood flow, especially during head-up tilt...
  23. pmc Cardiolocomotor coupling in young and elderly people
    Vera Novak
    Division of Gerontology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, USA
    J Gerontol A Biol Sci Med Sci 62:86-92. 2007
    ..Walking is a complex act that requires the coordination of locomotor, cardiovascular, and autonomic systems. Aging affects each of these systems and may alter physiological mechanisms regulating the interactions between them...
  24. pmc Cerebral blood flow velocity and periventricular white matter hyperintensities in type 2 diabetes
    Vera Novak
    Division of Gerontology, Beth Israel Deaconess Medical Center, 110 Francis St, Boston, MA 02215, USA
    Diabetes Care 29:1529-34. 2006
    ....
  25. pmc The relationship between blood pressure and cognitive function
    Vera Novak
    Division of Gerontology, Beth Israel Deaconess Medical Center and Harvard Medical School, 110 Francis Street, LMOB Suite 1b, Boston, MA 02215, USA
    Nat Rev Cardiol 7:686-98. 2010
    ..In this Review, we address the underlying pathophysiology and the existing evidence supporting the role of vascular factors in late-life cognitive decline...
  26. pmc Vasoreactivity and peri-infarct hyperintensities in stroke
    P Zhao
    Department of Medicine, Beth Israel Deaconess Medical Center, Boston, MA 02215, USA
    Neurology 72:643-9. 2009
    ..We investigated the regional differences in CO2 vasoreactivity (CO2 VR) and their relationships to peri-infarct T2 hyperintensities (PIHs), chronic infarct volumes, and clinical outcomes...
  27. pmc Global and regional effects of type 2 diabetes on brain tissue volumes and cerebral vasoreactivity
    David Last
    Division of Gerontology, Beth Israel Deaconess Medical Center, Harvard Medical School, 110 Francis St, Boston, MA 02215, USA
    Diabetes Care 30:1193-9. 2007
    ..The aim of this study was to evaluate the regional effects of type 2 diabetes and associated conditions on cerebral tissue volumes and cerebral blood flow (CBF) regulation...
  28. pmc Nonlinear phase interaction between nonstationary signals: a comparison study of methods based on Hilbert-Huang and Fourier transforms
    Men Tzung Lo
    Division of Gerontology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts 02215, USA
    Phys Rev E Stat Nonlin Soft Matter Phys 79:061924. 2009
    ..Furthermore, we propose certain strategies that can be implemented in the TFA and the MMPF methods to reduce the effects of nonstationarities, thus improving the performances of the two methods...
  29. ncbi request reprint Time-frequency mapping of R-R interval during complex partial seizures of temporal lobe origin
    V Novak
    Department of Neurology, The Ohio State University, Columbus 43210, USA
    J Auton Nerv Syst 77:195-202. 1999
    ..Activation of autonomic nervous system is common with seizures. No reliable biological markers of impending seizures have been found. Evaluation of autonomic changes might help elucidate the transition from interictal to ictal states...
  30. pmc Foot pressure distribution during walking in young and old adults
    Mary Josephine Hessert
    Division of Gerontology, Beth Israel Deaconess Medical Center Harvard Medical School, Boston, MA 02215, USA
    BMC Geriatr 5:8. 2005
    ..The effects of healthy aging on FPD during walking are not well known. This study evaluated FPD during normal walking in healthy young and elderly subjects...
  31. ncbi request reprint Comparison of 1.5 and 8 tesla high-resolution magnetic resonance imaging of lacunar infarcts
    Donald W Chakeres
    Department of Radiology, Sections of Neuroradiology and Magnetic Resonance Imaging Research, Boston Medical University, Harvard School of Medicine, Boston, Massachusetts, USA
    J Comput Assist Tomogr 26:628-32. 2002
    ..We present a case report comparing 1.5 fast spin-echo (FSE) and high-resolution 8 Tesla (T) gradient echo (GE) MRI of a patient with multiple lacunar infarcts...
  32. pmc Blood pressure and blood flow variation during postural change from sitting to standing: model development and validation
    Mette S Olufsen
    Department of Mathematics, North Carolina State University, Raleigh, 27695, USA
    J Appl Physiol 99:1523-37. 2005
    ..Finally, we formulate an inverse least-squares problem to estimate parameters and demonstrate that our mathematical model is in agreement with physiological data from a young subject during postural change from sitting to standing...
  33. ncbi request reprint Spectral analysis of slow modulation of EEG amplitude and cardiovascular variables in subjects with postural tachycardia syndrome
    Terrence D Lagerlund
    Department of Neurology, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, United States
    Auton Neurosci 117:132-42. 2005
    ....
  34. ncbi request reprint Effects of the anticholinesterase edrophonium on spectral analysis of heart rate and blood pressure variability in humans
    Alain Deschamps
    Department of Anesthesia, Royal Victoria Hospital, McGill University, Montreal, Quebec, Canada
    J Pharmacol Exp Ther 300:112-7. 2002
    ..These observations may account for the modest autonomic side effects of edrophonium when this drug is used clinically...
  35. ncbi request reprint Modeling baroreflex regulation of heart rate during orthostatic stress
    Mette S Olufsen
    Dept of Mathematics, North Carolina State Univ, Campus Box 8205, Raleigh, NC 27695, USA
    Am J Physiol Regul Integr Comp Physiol 291:R1355-68. 2006
    ....