M Niznikiewicz

Summary

Affiliation: Harvard University
Country: USA

Publications

  1. pmc Interactions between mood and the structure of semantic memory: event-related potentials evidence
    Ana P Pinheiro
    Neuropsychophysiology Lab, CIPSI, School of Psychology, University of Minho, Braga, Portugal
    Soc Cogn Affect Neurosci 8:579-94. 2013
  2. pmc Left auditory cortex gamma synchronization and auditory hallucination symptoms in schizophrenia
    Kevin M Spencer
    Research Service, Veterans Affairs Boston Healthcare System and Department of Psychiatry, Harvard Medical School, Research 151C, 150 S, Huntington Ave, Boston, MA 02130, USA
    BMC Neurosci 10:85. 2009
  3. doi request reprint Abnormal inhibitory processes in semantic networks in schizophrenia
    M Niznikiewicz
    Boston VA Medical Center, Boston, MA, USA
    Int J Psychophysiol 75:133-40. 2010
  4. pmc Semantic dysfunction in women with schizotypal personality disorder
    Margaret A Niznikiewicz
    Department of Psychiatry, Harvard Medical School, Boston, MA, USA
    Am J Psychiatry 159:1767-74. 2002
  5. doi request reprint Abnormal pitch mismatch negativity in individuals with schizotypal personality disorder
    Margaret A Niznikiewicz
    VA Boston Healthcare System Boston VA Healthcare System, Jamaica Plain VA and Brockton VA campuses, United States
    Schizophr Res 110:188-93. 2009
  6. ncbi request reprint Future directions for examining semantic memory in schizophrenia spectrum disorders
    M Niznikiewicz
    Harvard Medical School and Boston VA Healthcare System, Brockton, Massachusetts 02301, USA
    Clin EEG Neurosci 39:95-8. 2008
  7. pmc Processing sentence context in women with schizotypal personality disorder: an ERP study
    Margaret A Niznikiewicz
    Department of Psychiatry, Harvard Medical School, Neuroscience Laboratory, Brockton West Roxbury VAMC, Brockton, Massachusetts 02301, USA
    Psychophysiology 41:367-71. 2004
  8. pmc Semantic disturbance in schizophrenia and its relationship to the cognitive neuroscience of attention
    P G Nestor
    Department of Psychiatry, Harvard Medical School, Brockton VAMC 116A, 940 Belmont Street, Brockton, MA 02401, USA
    Biol Psychol 57:23-46. 2001
  9. pmc MRI study of caudate nucleus volume and its cognitive correlates in neuroleptic-naive patients with schizotypal personality disorder
    James J Levitt
    Clinical Neuroscience Division, Laboratory of Neuroscience, Dept of Psychiatry, VA Boston Healthcare System Brockton Division, Harvard Medical School, 940 Belmont Street, Brockton, MA 02301, USA
    Am J Psychiatry 159:1190-7. 2002
  10. pmc Fronto-temporal disconnectivity in schizotypal personality disorder: a diffusion tensor imaging study
    Motoaki Nakamura
    Clinical Neuroscience Division, Department of Psychiatry, Veterans Affairs Boston Healthcare System, Brockton Division, Harvard Medical School, MA 02301, USA
    Biol Psychiatry 58:468-78. 2005

Research Grants

Detail Information

Publications38

  1. pmc Interactions between mood and the structure of semantic memory: event-related potentials evidence
    Ana P Pinheiro
    Neuropsychophysiology Lab, CIPSI, School of Psychology, University of Minho, Braga, Portugal
    Soc Cogn Affect Neurosci 8:579-94. 2013
    ..These findings suggest the differential impact of mood on access to long-term semantic memory during sentence comprehension...
  2. pmc Left auditory cortex gamma synchronization and auditory hallucination symptoms in schizophrenia
    Kevin M Spencer
    Research Service, Veterans Affairs Boston Healthcare System and Department of Psychiatry, Harvard Medical School, Research 151C, 150 S, Huntington Ave, Boston, MA 02130, USA
    BMC Neurosci 10:85. 2009
    ..A 5-dipole model was fit from the HC grand average ASSR, with 2 pairs of superior temporal dipoles and a deep midline dipole. Time-frequency decomposition was performed on the scalp EEG and source data...
  3. doi request reprint Abnormal inhibitory processes in semantic networks in schizophrenia
    M Niznikiewicz
    Boston VA Medical Center, Boston, MA, USA
    Int J Psychophysiol 75:133-40. 2010
    ..Furthermore, reduced N400 in the unrelated condition found in this study suggests that the abnormality was related to inefficient early inhibitory processes...
  4. pmc Semantic dysfunction in women with schizotypal personality disorder
    Margaret A Niznikiewicz
    Department of Psychiatry, Harvard Medical School, Boston, MA, USA
    Am J Psychiatry 159:1767-74. 2002
    ..The N400 component of the EEG event-related potentials was used as a probe of semantic processes...
  5. doi request reprint Abnormal pitch mismatch negativity in individuals with schizotypal personality disorder
    Margaret A Niznikiewicz
    VA Boston Healthcare System Boston VA Healthcare System, Jamaica Plain VA and Brockton VA campuses, United States
    Schizophr Res 110:188-93. 2009
    ..Biological Psychiatry (2006); 59(8):762-772], in recent onset schizophrenia patients. To our knowledge no reports exist of MMN in SPD individuals...
  6. ncbi request reprint Future directions for examining semantic memory in schizophrenia spectrum disorders
    M Niznikiewicz
    Harvard Medical School and Boston VA Healthcare System, Brockton, Massachusetts 02301, USA
    Clin EEG Neurosci 39:95-8. 2008
    ..In addition, the review points to future directions of study of the areas that received little attention thus far and whose investigation might contribute to a more detailed understanding of semantic memory dysfunction in schizophrenia...
  7. pmc Processing sentence context in women with schizotypal personality disorder: an ERP study
    Margaret A Niznikiewicz
    Department of Psychiatry, Harvard Medical School, Neuroscience Laboratory, Brockton West Roxbury VAMC, Brockton, Massachusetts 02301, USA
    Psychophysiology 41:367-71. 2004
    ..In SPD women, relative to their comparison group, a more negative N400 was found only to auditory congruent sentences...
  8. pmc Semantic disturbance in schizophrenia and its relationship to the cognitive neuroscience of attention
    P G Nestor
    Department of Psychiatry, Harvard Medical School, Brockton VAMC 116A, 940 Belmont Street, Brockton, MA 02401, USA
    Biol Psychol 57:23-46. 2001
    ..We propose a similar failure of NMDA-mediated recurrent inhibition as a candidate biological substrate for attention and semantic anomalies of schizophrenia...
  9. pmc MRI study of caudate nucleus volume and its cognitive correlates in neuroleptic-naive patients with schizotypal personality disorder
    James J Levitt
    Clinical Neuroscience Division, Laboratory of Neuroscience, Dept of Psychiatry, VA Boston Healthcare System Brockton Division, Harvard Medical School, 940 Belmont Street, Brockton, MA 02301, USA
    Am J Psychiatry 159:1190-7. 2002
    ....
  10. pmc Fronto-temporal disconnectivity in schizotypal personality disorder: a diffusion tensor imaging study
    Motoaki Nakamura
    Clinical Neuroscience Division, Department of Psychiatry, Veterans Affairs Boston Healthcare System, Brockton Division, Harvard Medical School, MA 02301, USA
    Biol Psychiatry 58:468-78. 2005
    ..Here, we investigate these two bundles in unmedicated subjects with schizotypal personality disorder (SPD)...
  11. pmc An MRI study of superior temporal gyrus volume in women with schizotypal personality disorder
    Chandlee C Dickey
    VA Boston Healthcare System, Psychiatry 116A, 940 Belmont St, Brockton, MA 02401, USA
    Am J Psychiatry 160:2198-201. 2003
    ..This is the first structural magnetic resonance imaging study to examine a group of female subjects with schizotypal personality disorder...
  12. pmc Functional and structural deficits in brain regions subserving face perception in schizophrenia
    Toshiaki Onitsuka
    Department of Psychiatry, VA Boston Healthcare System, Brockton Division, Harvard Medical School, Brockton, MA 02301, USA
    Am J Psychiatry 163:455-62. 2006
    ....
  13. pmc A prospective longitudinal volumetric MRI study of superior temporal gyrus gray matter and amygdala-hippocampal complex in chronic schizophrenia
    Takeshi Yoshida
    Clinical Neuroscience Division, Laboratory of Neuroscience, Department of Psychiatry, Boston VA Healthcare System, Brockton Division and Harvard Medical School, Brockton, MA 02301, USA
    Schizophr Res 113:84-94. 2009
    ..These data, and separately reported first episode data from our laboratory, suggest marked progression at the initial stage of schizophrenia, but less in chronic schizophrenia...
  14. pmc Neural synchrony indexes disordered perception and cognition in schizophrenia
    Kevin M Spencer
    Department of Psychiatry, Veterans Affairs Boston Healthcare System, Harvard Medical School, Psychiatry 116A, 940 Belmont Street, Brockton, MA 02301, USA
    Proc Natl Acad Sci U S A 101:17288-93. 2004
    ..These data provide support for linking dysfunctional neural circuitry and the core symptoms of schizophrenia...
  15. pmc Reduction of caudate nucleus volumes in neuroleptic-naïve female subjects with schizotypal personality disorder
    Min Seong Koo
    Clinical Neuroscience Division, Laboratory of Neuroscience, Department of Psychiatry, Veterans Affairs Boston Healthcare System, Brockton Division, Brockton, and Harvard Medical School, Boston, MA 02401, USA
    Biol Psychiatry 60:40-8. 2006
    ....
  16. pmc A MRI study of fusiform gyrus in schizotypal personality disorder
    Chandlee C Dickey
    Laboratory of Neuroscience, Department of Psychiatry, VA Boston Healthcare System, and Surgical Planning Laboratory, MRI Division, Department of Radiology, Brigham and Women s Hospital, Harvard Medical School, Boston, MA, USA
    Schizophr Res 64:35-9. 2003
    ..This suggests that future studies may be useful in determining the functional competence of this gyrus in SPD...
  17. pmc Smaller left Heschl's gyrus volume in patients with schizotypal personality disorder
    Chandlee C Dickey
    Harvard Medical School, Clinical Neuroscience Division, Department of Psychiatry, VA Boston Healthcare System, Brockton, MA 02401, USA
    Am J Psychiatry 159:1521-7. 2002
    ..In a further exploration, the authors studied two components of the superior temporal gyrus: Heschl's gyrus and the planum temporale...
  18. pmc Factors in sensory processing of prosody in schizotypal personality disorder: an fMRI experiment
    Chandlee C Dickey
    Serious Mental Illness Program, VA Boston Healthcare System, Psychiatry 116A 7, 940 Belmont St, Brockton, MA 02301, United States
    Schizophr Res 121:75-89. 2010
    ..The superior temporal gyrus (STG) was selected as the region-of-interest (ROI) given its known abnormalities in SPD and its important role in the processing of prosody...
  19. pmc Dichotic listening in schizotypal personality disorder: evidence for gender and laterality effects
    Martina M Voglmaier
    Department of Psychiatry at MMHC Public Psychiatry Division of Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, United States
    Schizophr Res 115:290-2. 2009
    ..The results suggest that left hemisphere temporal lobe structures may be particularly involved in male, but not female, SPD...
  20. pmc Shape abnormalities of caudate nucleus in schizotypal personality disorder
    James J Levitt
    Laboratory of Neuroscience, Department of Psychiatry, Veterans Affairs Boston Healthcare System, Brockton Division, Harvard Medical School, Brockton, MA, USA
    Schizophr Res 110:127-39. 2009
    ..Here, we use a new shape measure which importantly permits local in addition to global shape analysis, as well as local correlations with behavioral measures...
  21. pmc The startle reflex in schizophrenia: habituation and personality correlates
    Sare J Akdag
    Department of Psychology, University of Massachusetts Boston, 100 Morrissey Boulevard, Boston, MA 02125, USA
    Schizophr Res 64:165-73. 2003
    ..The relationship of these findings to cognitive disturbances in schizophrenia is considered and directions for future research are discussed...
  22. pmc A comparative profile analysis of neuropsychological function in men and women with schizotypal personality disorder
    Martina M Voglmaier
    Harvard Medical School, Department of Psychiatry at the Massachusetts Mental Health Center, Boston, MA 02139, USA
    Schizophr Res 74:43-9. 2005
    ..The results suggest a less severe pattern of cognitive deficits in women with SPD compared to men, consistent with hypotheses of gender differences in cognitive function in schizophrenia...
  23. pmc Auditory processing abnormalities in schizotypal personality disorder: an fMRI experiment using tones of deviant pitch and duration
    Chandlee C Dickey
    Serious Mental Illness Program, VA Boston Healthcare System, Psychiatry 116A RC, 940 Belmont St, Brockton, MA 02401, United States
    Schizophr Res 103:26-39. 2008
    ..The focus of this study was to determine whether or not there are also processing abnormalities of pure tones differing in pitch and duration in SPD...
  24. pmc Sensory-evoked gamma oscillations in chronic schizophrenia
    Kevin M Spencer
    Department of Psychiatry, VA Boston Healthcare System, Harvard Medical School, Brockton, Massachusetts 02301, USA
    Biol Psychiatry 63:744-7. 2008
    ..We investigated these issues by examining the VGO and AGO in chronic schizophrenic (SZ) and matched healthy control (HC) subjects...
  25. pmc MRI abnormalities of the hippocampus and cavum septi pellucidi in females with schizotypal personality disorder
    Chandlee C Dickey
    Clinical Neuroscience Division, Laboratory of Neuroscience, Department of Psychiatry, VA Boston Healthcare System, Harvard Medical School, Boston, MA, USA
    Schizophr Res 89:49-58. 2007
    ..This study examined MRI hippocampal volume and cavum septi pellucidi (CSP) in female subjects with schizotypal personality disorder (SPD) and comparison subjects...
  26. pmc Clinical, cognitive, and social characteristics of a sample of neuroleptic-naive persons with schizotypal personality disorder
    Chandlee C Dickey
    Clinical Neuroscience Division, Laboratory of Neuroscience, Department of Psychiatry, VA Boston Healthcare System, Harvard Medical School, Psychiatry 116A, 940 Belmont St, Brockton, MA 02401, USA
    Schizophr Res 78:297-308. 2005
    ..This report describes the clinical, cognitive and socio-occupational characteristics of a community sample of subjects diagnosed with SPD...
  27. pmc Enhanced facilitation of spatial attention in schizophrenia
    Kevin M Spencer
    Veterans Affairs Boston Healthcare System Harvard Medical School, Research 151C, 150 S Huntington Avenue, Boston, MA 02130, USA
    Neuropsychology 25:76-85. 2011
    ..We tested this hypothesis with orienting tasks involving the cued detection of a laterally presented target stimulus...
  28. pmc Gray matter volume reduction in rostral middle frontal gyrus in patients with chronic schizophrenia
    Z Kikinis
    Psychiatry Neuroimaging Laboratory, Department of Psychiatry, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02215, USA
    Schizophr Res 123:153-9. 2010
    ..This method of parcellation offers a more precise way of measuring MR-MFG that will likely be important in further documentation of DLPFC anomalies in schizophrenia...
  29. pmc DTI and MTR abnormalities in schizophrenia: analysis of white matter integrity
    M Kubicki
    Clinical Neuroscience Division, Laboratory of Neuroscience, Boston VA Healthcare System Brockton Division, Department of Psychiatry, Harvard Medical School, Brockton, MA 02301, USA
    Neuroimage 26:1109-18. 2005
    ....
  30. pmc Association between reduced extraversion and right posterior fusiform gyrus gray matter reduction in chronic schizophrenia
    Toshiaki Onitsuka
    Department of Psychiatry, Boston VA Healthcare System Brockton Division, Harvard Medical School, 940 Belmont St, Brockton, MA 02301, USA
    Am J Psychiatry 162:599-601. 2005
    ..The authors examined the association between volume of the fusiform gyrus, a region involved in face processing, and the personality trait of extraversion in patients with schizophrenia...
  31. pmc Color Stroop and negative priming in schizophrenia: an fMRI study
    Lida Ungar
    Psychiatry Neuroimaging Laboratory, Department of Psychiatry, Brigham and Women s Hospital, Harvard Medical School, 1249 Boylston Street 3rd Floor, Boston, MA 02215, USA
    Psychiatry Res 181:24-9. 2010
    ..These different patterns of fMRI activation may reflect faulty interaction in schizophrenia within networks of brain regions that are vital to selective attention...
  32. pmc Abnormal neural synchrony in schizophrenia
    Kevin M Spencer
    Department of Psychiatry, Harvard Medical School Veterans Affairs Boston Healthcare System, Brockton, Massachusetts 02301, USA
    J Neurosci 23:7407-11. 2003
    ..These findings support the hypothesis that schizophrenia is associated with impaired neural circuitry demonstrated as a failure of gamma band synchronization, especially in the 40 Hz range...
  33. pmc The five-factor model in schizotypal personality disorder
    Ronald J Gurrera
    Harvard Medical School, Department of Psychiatry, Boston, MA, USA
    Schizophr Res 80:243-51. 2005
    ..These findings suggest that gender-associated differences in openness may account for prior inconsistent findings regarding this dimension, and they further underscore the importance of examining gender effects in future studies of SPD...
  34. ncbi request reprint Clozapine action on auditory P3 response in schizophrenia
    Margaret A Niznikiewicz
    Schizophr Res 76:119-21. 2005
  35. pmc Early nicotine withdrawal and transdermal nicotine effects on neurocognitive performance in schizophrenia
    Christopher G AhnAllen
    Center for Alcohol and Addictions Studies, Brown University, 121 South Main St, Providence, RI, 02912, USA
    Schizophr Res 100:261-9. 2008
    ....
  36. pmc The uncinate fasciculus and extraversion in schizotypal personality disorder: a diffusion tensor imaging study
    Ronald J Gurrera
    Schizophr Res 90:360-2. 2007

Research Grants7

  1. Language Systems in Schizophrenia: Behavioral & ERP Data
    Margaret Niznikiewicz; Fiscal Year: 2006
    ..Correlational analyses among the four data sets will seek to characterize the relationships among the four domains of analysis.We predict that females will show less impairment than males on all these measures. ..
  2. Semantic knowledge and its underlying structures in schizophrenia-an fMRI study
    Margaret Niznikiewicz; Fiscal Year: 2007
    ..Thus, in this application we propose to use fMRI to describe possible abnormalities in semantic memory structure in schizophrenia and identify which brain structures are involved in mediating these abnormalities. ..