Affiliation: Harvard University
- Determination of the specific substrate sequence motifs of protein kinase C isozymesK Nishikawa
Division of Signal Transduction, Beth Israel Hospital, Boston, Massachusetts 02115, USA
J Biol Chem 272:952-60. 1997..The structural basis for the selectivity of PKC isozymes is discussed based on residues predicted to form the catalytic cleft...
- Association of protein kinase Cmu with type II phosphatidylinositol 4-kinase and type I phosphatidylinositol-4-phosphate 5-kinaseK Nishikawa
Division of Signal Transduction, Beth Israel Deaconess Medical Center and Department of Cell Biology, Harvard Medical School, Boston, Massachusetts 02115, USA
J Biol Chem 273:23126-33. 1998..These results suggest a novel model in which the non-catalytic region of PKCmu acts as a scaffold for assembly of enzymes involved in phosphoinositide synthesis at specific membrane locations...