MingMing Ning

Summary

Affiliation: Harvard University
Country: USA

Publications

  1. doi request reprint Pharmaco-proteomics opportunities for individualizing neurovascular treatment
    M M Ning
    Clinical Proteomics Research Center, Department of Neurology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA
    Neurol Res 35:448-56. 2013
  2. pmc The brain's heart - therapeutic opportunities for patent foramen ovale (PFO) and neurovascular disease
    MingMing Ning
    Cardio Neurology Clinic, Massachusetts General Hospital, Harvard Medical School, USA
    Pharmacol Ther 139:111-23. 2013
  3. pmc Application of proteomics to cerebrovascular disease
    MingMing Ning
    Clinical Proteomics Research Center, Department of Neurology, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA
    Electrophoresis 33:3582-97. 2012
  4. pmc Proteomic temporal profile of human brain endothelium after oxidative stress
    MingMing Ning
    Clinical Proteomics Research Center, Massachusetts General Hospital, Harvard Medial School, Boston, MA, USA
    Stroke 42:37-43. 2011
  5. pmc The vasculome of the mouse brain
    Shuzhen Guo
    Neuroprotection Research Laboratory, Departments of Radiology and Neurology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA
    PLoS ONE 7:e52665. 2012
  6. pmc Heart-brain signaling in patent foramen ovale-related stroke: differential plasma proteomic expression patterns revealed with a 2-pass liquid chromatography-tandem mass spectrometry discovery workflow
    Mary F Lopez
    Thermo Fisher Scientific BRIMS, Cambridge, MA 02139, USA
    J Investig Med 60:1122-30. 2012
  7. doi request reprint Studying extracellular signaling utilizing a glycoproteomic approach: lectin blot surveys, a first and important step
    Jing Cao
    Neuroprotection Research Laboratory, Massachussetts General Hospital and Harvard Medical School, Boston, MA, USA
    Methods Mol Biol 1013:227-33. 2013
  8. pmc Early elevation of serum tumor necrosis factor-α is associated with poor outcome in subarachnoid hemorrhage
    Sherry H Y Chou
    Department of Neurology, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02114, USA
    J Investig Med 60:1054-8. 2012
  9. pmc Amelioration of inflammation and cytotoxicity by dipyridamole in brain endothelial cells
    Shuzhen Guo
    Neuroprotection Research Laboratory, Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Boston, Mass, USA
    Cerebrovasc Dis 30:290-6. 2010
  10. pmc Early insulin glycemic control combined with tPA thrombolysis reduces acute brain tissue damages in a focal embolic stroke model of diabetic rats
    Xiang Fan
    Neuroprotection Research Laboratory, Departments of Neurology and Radiology, Massachusetts General Hospital, Harvard Medical School, 149 13th Street, Room 2411A, Charlestown, MA 02129, USA
    Stroke 44:255-9. 2013

Collaborators

Detail Information

Publications22

  1. doi request reprint Pharmaco-proteomics opportunities for individualizing neurovascular treatment
    M M Ning
    Clinical Proteomics Research Center, Department of Neurology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA
    Neurol Res 35:448-56. 2013
    ..In the future, this clinical proteomics approach may help to improve patient selection, ensure more precise clinical phenotyping for clinical trials, and individualize patient treatment...
  2. pmc The brain's heart - therapeutic opportunities for patent foramen ovale (PFO) and neurovascular disease
    MingMing Ning
    Cardio Neurology Clinic, Massachusetts General Hospital, Harvard Medical School, USA
    Pharmacol Ther 139:111-23. 2013
    ....
  3. pmc Application of proteomics to cerebrovascular disease
    MingMing Ning
    Clinical Proteomics Research Center, Department of Neurology, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA
    Electrophoresis 33:3582-97. 2012
    ....
  4. pmc Proteomic temporal profile of human brain endothelium after oxidative stress
    MingMing Ning
    Clinical Proteomics Research Center, Massachusetts General Hospital, Harvard Medial School, Boston, MA, USA
    Stroke 42:37-43. 2011
    ..because brain endothelial cells exist at the neurovascular interface, they may serve as cellular reporters of brain dysfunction by releasing biomarkers into the circulation...
  5. pmc The vasculome of the mouse brain
    Shuzhen Guo
    Neuroprotection Research Laboratory, Departments of Radiology and Neurology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA
    PLoS ONE 7:e52665. 2012
    ..Mapping and dissecting the vasculome of the brain in health and disease may provide a novel database for investigating disease mechanisms, assessing therapeutic targets and exploring new biomarkers for the CNS...
  6. pmc Heart-brain signaling in patent foramen ovale-related stroke: differential plasma proteomic expression patterns revealed with a 2-pass liquid chromatography-tandem mass spectrometry discovery workflow
    Mary F Lopez
    Thermo Fisher Scientific BRIMS, Cambridge, MA 02139, USA
    J Investig Med 60:1122-30. 2012
    ..These findings demonstrate the feasibility and robustness of using a proteomic approach for biomarker discovery to help gauge therapeutic efficacy in stroke...
  7. doi request reprint Studying extracellular signaling utilizing a glycoproteomic approach: lectin blot surveys, a first and important step
    Jing Cao
    Neuroprotection Research Laboratory, Massachussetts General Hospital and Harvard Medical School, Boston, MA, USA
    Methods Mol Biol 1013:227-33. 2013
    ..Here, we will use patient plasma samples post hypothermic therapy-an extremely complex medium-as a tool to describe in detail the technique of lectin blotting for proteomic analysis...
  8. pmc Early elevation of serum tumor necrosis factor-α is associated with poor outcome in subarachnoid hemorrhage
    Sherry H Y Chou
    Department of Neurology, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02114, USA
    J Investig Med 60:1054-8. 2012
    ..We hypothesize that elevated serum tumor necrosis factor α (TNF-α) and interleukin 6 (IL-6) are associated with vasospasm and poor outcome in SAH...
  9. pmc Amelioration of inflammation and cytotoxicity by dipyridamole in brain endothelial cells
    Shuzhen Guo
    Neuroprotection Research Laboratory, Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Boston, Mass, USA
    Cerebrovasc Dis 30:290-6. 2010
    ..In this experimental cellular study, we asked whether dipyridamole can ameliorate brain endothelial injury after exposure to inflammatory and metabolic insults...
  10. pmc Early insulin glycemic control combined with tPA thrombolysis reduces acute brain tissue damages in a focal embolic stroke model of diabetic rats
    Xiang Fan
    Neuroprotection Research Laboratory, Departments of Neurology and Radiology, Massachusetts General Hospital, Harvard Medical School, 149 13th Street, Room 2411A, Charlestown, MA 02129, USA
    Stroke 44:255-9. 2013
    ..In this study, we tested the effects of insulin plus tPA combination in a model of focal embolic stroke in Type I diabetic rats...
  11. ncbi request reprint Hemorrhage burden predicts recurrent intracerebral hemorrhage after lobar hemorrhage
    Steven M Greenberg
    Department of Neurology, Massachusetts General Hospital and Harvard Medical School, Boston, Mass 02114, USA
    Stroke 35:1415-20. 2004
    ..We sought to determine whether hemorrhages detected at the time of lobar ICH predict the major clinical complications of CAA: recurrent ICH or decline in cognition and function...
  12. pmc Neurovascular effects of CD47 signaling: promotion of cell death, inflammation, and suppression of angiogenesis in brain endothelial cells in vitro
    Changhong Xing
    Neuroprotection Research Laboratory, Department of Radiology and Neurology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts 02129, USA
    J Neurosci Res 87:2571-7. 2009
    ..We conclude that CD47 signaling can negatively affect the viability and function of cerebral endothelial cells, further supporting the notion that CD47 may be a potential neurovascular target for stroke and brain injury...
  13. doi request reprint Evaluation of plasma D-dimer plus fibrinogen in predicting acute CVST
    Ran Meng
    Cerebral Vascular Diseases Research Institute China America Institute of Neuroscience and Neurology Department, Xuanwu Hospital, Capital Medical University, Key Lab of Neurodegenerative Diseases of Ministry of Education, Beijing, China Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA
    Int J Stroke 9:166-73. 2014
    ..Prompt diagnosis of cerebral venous sinus thrombosis is a challenge owing in part to its complex and non-specific early clinical symptoms...
  14. doi request reprint Pearls and Oy-sters: Reversible iatrogenic Balint syndrome
    Nicte I Mejia
    Department of Neurology, Massachusetts General Hospital, Boston, MA 02114, USA
    Neurology 70:e97-8. 2008
  15. pmc May-Thurner syndrome in patients with cryptogenic stroke and patent foramen ovale: an important clinical association
    Thomas J Kiernan
    Department of Interventional Cardiology and Vascular Medicine, Massachusetts General Hospital, Boston, MA 02114, USA
    Stroke 40:1502-4. 2009
    ..We aimed to investigate the incidence of May-Thurner syndrome in patients with cryptogenic stroke with patent foramen ovale...
  16. doi request reprint Discrimination of ischemic and hemorrhagic strokes using a multiplexed, mass spectrometry-based assay for serum apolipoproteins coupled to multi-marker ROC algorithm
    Mary F Lopez
    ThermoFisher Scientific BRIMS, Cambridge, MA, USA
    Proteomics Clin Appl 6:190-200. 2012
    ..In this report, we describe the development of a multiplexed selected reaction monitoring (SRM) based assay for a panel of apolipoproteins and its application to a clinical cohort of samples derived from acute stroke patients...
  17. pmc Cerebral edema and a transtentorial brain herniation syndrome associated with pandemic swine influenza A (H1N1) virus infection
    Kristopher T Kahle
    Department of Neurosurgery, Massachusetts General Hospital and Harvard Medical School, White Building, Room 502, 55 Fruit Street, Boston, Massachusetts 02114, USA
    J Clin Neurosci 18:1245-8. 2011
    ....
  18. ncbi request reprint Comparison of clinical characteristics and functional outcomes of ischemic stroke in different vascular territories
    Yee Sien Ng
    Department of Rehabilitation Medicine, Spaulding Rehabilitation Hospital, Harvard Medical School, Boston, MA, USA
    Stroke 38:2309-14. 2007
    ..Such comparative data are important in functional prognostication, rehabilitation, and healthcare planning, but literature is scarce and isolated...
  19. ncbi request reprint Mechanisms of hemorrhagic transformation after tissue plasminogen activator reperfusion therapy for ischemic stroke
    Xiaoying Wang
    Department of Radiology, Massachusetts General Hospital and Harvard Medical School, Boston, Mass, USA
    Stroke 35:2726-30. 2004
    ..Understanding these pleiotropic actions of tPA may reveal new therapeutic opportunities for combination stroke therapy...
  20. pmc Plasma-type gelsolin is decreased in human blood and cerebrospinal fluid after subarachnoid hemorrhage
    Sherry H Y Chou
    Department of Neurology, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02114, USA
    Stroke 42:3624-7. 2011
    ..How these 2 phenomena are related remains unclear. We hypothesize that matrix metalloproteinases (MMPs) mediate the depletion of anti-inflammatory plasma-type gelsolin (pGSN)...
  21. doi request reprint Spinal dural arteriovenous fistula mimicking prostate hyperplasia
    Sarah I Sheikh
    Department of Neurology, Massachusetts General Hospital, Boston, Massachusetts, USA
    J Emerg Med 41:e137-40. 2011
    ..Presenting symptoms are often common complaints in general practice or the emergency department, such as leg weakness or numbness. One of the less recognized early features is that of sphincteric disturbance...
  22. ncbi request reprint Preventing a second stroke in the young
    MingMing Ning
    Massachusetts General Hospital, Boston, Massachusetts, USA
    Top Stroke Rehabil 11:40-50. 2004
    ....