Lise E Nigrovic

Summary

Affiliation: Harvard University
Country: USA

Publications

  1. ncbi Aseptic meningitis
    Lise E Nigrovic
    Department of Medicine, Children s Hospital Boston and Harvard Medical School, Boston, MA, USA Electronic address
    Handb Clin Neurol 112:1153-6. 2013
  2. ncbi Trends in the Management of Viral Meningitis at United States Children's Hospitals
    Lise E Nigrovic
    Division of Emergency Medicine, Boston Children s Hospital, 300 Longwood Ave, Boston, MA 02115
    Pediatrics 131:670-6. 2013
  3. ncbi Meta-analysis of bacterial meningitis score validation studies
    Lise E Nigrovic
    Division of Emergency Medicine, Department of Pediatrics, Children s Hospital Boston and Harvard Medical School, 300 Longwood Avenue, Boston, MA 02115, USA
    Arch Dis Child 97:799-805. 2012
  4. ncbi Utility of plain radiographs in detecting traumatic injuries of the cervical spine in children
    Lise E Nigrovic
    Division of Emergency Medicine, Children s Hospital Boston and Harvard Medical School, Boston, MA 02115, USA
    Pediatr Emerg Care 28:426-32. 2012
  5. ncbi Prevalence of clinically important traumatic brain injuries in children with minor blunt head trauma and isolated severe injury mechanisms
    Lise E Nigrovic
    Division of Emergency Medicine, Children s Hospital, Boston, 300 Longwood Ave, Boston, MA 02115, USA
    Arch Pediatr Adolesc Med 166:356-61. 2012
  6. ncbi Correction of cerebrospinal fluid protein for the presence of red blood cells in children with a traumatic lumbar puncture
    Lise E Nigrovic
    Division of Emergency Medicine, Department of Pediatrics, Children s Hospital Boston and Harvard Medical School, Boston, MA 02115, USA
    J Pediatr 159:158-9. 2011
  7. ncbi The effect of observation on cranial computed tomography utilization for children after blunt head trauma
    Lise E Nigrovic
    Division of Emergency Medicine, Children s Hospital Boston, Boston, Boston, MA 02115, USA
    Pediatrics 127:1067-73. 2011
  8. ncbi Cerebrospinal fluid pleocytosis in children in the era of bacterial conjugate vaccines: distinguishing the child with bacterial and aseptic meningitis
    Lise E Nigrovic
    Division of Emergency Medicine, Children s Hospital Boston and Harvard Medical School, Boston, MA 02115, USA
    Pediatr Emerg Care 25:112-7; quiz 118-20. 2009
  9. ncbi Clinical predictors of Lyme disease among children with a peripheral facial palsy at an emergency department in a Lyme disease-endemic area
    Lise E Nigrovic
    Division of Emergency Medicine, Children s Hospital Boston, Boston, Massachusetts 02115, USA
    Pediatrics 122:e1080-5. 2008
  10. ncbi Effect of antibiotic pretreatment on cerebrospinal fluid profiles of children with bacterial meningitis
    Lise E Nigrovic
    Children s Hospital Boston and Harvard Medical School, Boston, MA 02115, USA
    Pediatrics 122:726-30. 2008

Detail Information

Publications33

  1. ncbi Aseptic meningitis
    Lise E Nigrovic
    Department of Medicine, Children s Hospital Boston and Harvard Medical School, Boston, MA, USA Electronic address
    Handb Clin Neurol 112:1153-6. 2013
    ....
  2. ncbi Trends in the Management of Viral Meningitis at United States Children's Hospitals
    Lise E Nigrovic
    Division of Emergency Medicine, Boston Children s Hospital, 300 Longwood Ave, Boston, MA 02115
    Pediatrics 131:670-6. 2013
    ..To determine trends in the diagnosis and management of children with viral meningitis at US children's hospitals...
  3. ncbi Meta-analysis of bacterial meningitis score validation studies
    Lise E Nigrovic
    Division of Emergency Medicine, Department of Pediatrics, Children s Hospital Boston and Harvard Medical School, 300 Longwood Avenue, Boston, MA 02115, USA
    Arch Dis Child 97:799-805. 2012
    ..The study objective of the present work was to calculate the performance of the Bacterial Meningitis Score by performing a meta-analysis of all published validation studies...
  4. ncbi Utility of plain radiographs in detecting traumatic injuries of the cervical spine in children
    Lise E Nigrovic
    Division of Emergency Medicine, Children s Hospital Boston and Harvard Medical School, Boston, MA 02115, USA
    Pediatr Emerg Care 28:426-32. 2012
    ..The objective of this study was to estimate the sensitivity of plain radiographs in identifying bony or ligamentous cervical spine injury in children...
  5. ncbi Prevalence of clinically important traumatic brain injuries in children with minor blunt head trauma and isolated severe injury mechanisms
    Lise E Nigrovic
    Division of Emergency Medicine, Children s Hospital, Boston, 300 Longwood Ave, Boston, MA 02115, USA
    Arch Pediatr Adolesc Med 166:356-61. 2012
    ....
  6. ncbi Correction of cerebrospinal fluid protein for the presence of red blood cells in children with a traumatic lumbar puncture
    Lise E Nigrovic
    Division of Emergency Medicine, Department of Pediatrics, Children s Hospital Boston and Harvard Medical School, Boston, MA 02115, USA
    J Pediatr 159:158-9. 2011
    ..For every 1000 cell increase in CSF red blood cells per mm(3), CSF protein increases by 1.1 mg/dL (95% CI, 0.9-1.1 mg/dL)...
  7. ncbi The effect of observation on cranial computed tomography utilization for children after blunt head trauma
    Lise E Nigrovic
    Division of Emergency Medicine, Children s Hospital Boston, Boston, Boston, MA 02115, USA
    Pediatrics 127:1067-73. 2011
    ..Children with minor blunt head trauma often are observed in the emergency department before a decision is made regarding computed tomography use. We studied the impact of this clinical strategy on computed tomography use and outcomes...
  8. ncbi Cerebrospinal fluid pleocytosis in children in the era of bacterial conjugate vaccines: distinguishing the child with bacterial and aseptic meningitis
    Lise E Nigrovic
    Division of Emergency Medicine, Children s Hospital Boston and Harvard Medical School, Boston, MA 02115, USA
    Pediatr Emerg Care 25:112-7; quiz 118-20. 2009
    ....
  9. ncbi Clinical predictors of Lyme disease among children with a peripheral facial palsy at an emergency department in a Lyme disease-endemic area
    Lise E Nigrovic
    Division of Emergency Medicine, Children s Hospital Boston, Boston, Massachusetts 02115, USA
    Pediatrics 122:e1080-5. 2008
    ..Although Lyme disease can cause peripheral facial palsy in Lyme disease-endemic areas, diagnostic predictors in children have not been described...
  10. ncbi Effect of antibiotic pretreatment on cerebrospinal fluid profiles of children with bacterial meningitis
    Lise E Nigrovic
    Children s Hospital Boston and Harvard Medical School, Boston, MA 02115, USA
    Pediatrics 122:726-30. 2008
    ..The goal of this study was to evaluate the effect of antibiotic administration before lumbar puncture on cerebrospinal fluid profiles in children with bacterial meningitis...
  11. ncbi Tularemia
    Lise E Nigrovic
    Division of Emergency Medicine, Children s Hospital, Boston, 300 Longwood Avenue, Boston, MA 02115, USA
    Infect Dis Clin North Am 22:489-504, ix. 2008
    ..Recent world events have led to a new recognition of F tularensis as a viable agent of bioterrorism, which has sparked a renewed focus on this pathogen...
  12. ncbi Children with bacterial meningitis presenting to the emergency department during the pneumococcal conjugate vaccine era
    Lise E Nigrovic
    Division of Emergency Medicine, Children s Hospital, Boston, MA, USA
    Acad Emerg Med 15:522-8. 2008
    ..The epidemiology of bacterial meningitis in children in the era of widespread heptavalent conjugate pneumococcal vaccination (PCV7) is unknown...
  13. ncbi Cerebrospinal fluid xanthochromia in newborns is related to maternal labor before delivery
    Lise E Nigrovic
    Division of Emergency Medicine, Children s Hospital Boston, 300 Longwood Ave, Boston, MA 02115, USA
    Pediatrics 120:e1212-6. 2007
    ..The purpose of this work was to investigate whether xanthochromia in newborns is related to maternal labor before delivery...
  14. ncbi Lumbar puncture success rate is not influenced by family-member presence
    Lise E Nigrovic
    Division of Emergency Medicine, Children s Hospital Boston and Harvard Medical School, Boston, MA 02115, USA
    Pediatrics 120:e777-82. 2007
    ..However, family presence might also affect clinicians' stress and anxiety, with uncertain consequences for procedural success...
  15. ncbi Risk factors for traumatic or unsuccessful lumbar punctures in children
    Lise E Nigrovic
    Division of Emergency Medicine, Children s Hospital and Harvard Medical School, Boston, MA 02115, USA
    Ann Emerg Med 49:762-71. 2007
    ..We sought to determine patient, physician, and procedural factors associated with traumatic and unsuccessful lumbar punctures in children...
  16. ncbi Clinical prediction rule for identifying children with cerebrospinal fluid pleocytosis at very low risk of bacterial meningitis
    Lise E Nigrovic
    Department of Medicine, Children s Hospital Boston and Harvard Medical School, Boston, Mass 02115, USA
    JAMA 297:52-60. 2007
    ....
  17. ncbi Integrating spatial epidemiology into a decision model for evaluation of facial palsy in children
    Andrew M Fine
    Division of Emergency Medicine, Children s Hospital Boston, Boston, MA 02115, USA
    Arch Pediatr Adolesc Med 165:61-7. 2011
    ..To develop a novel diagnostic algorithm for Lyme disease among children with facial palsy by integrating public health surveillance data with traditional clinical predictors...
  18. ncbi Diagnostic value of immature neutrophils (bands) in the cerebrospinal fluid of children with cerebrospinal fluid pleocytosis
    John T Kanegaye
    Division of Emergency Medicine, Rady Children s Hospital San Diego, 3020 Children s Way, MC 5075, San Diego, CA 92123, USA
    Pediatrics 123:e967-71. 2009
    ..We evaluated the diagnostic utility of the presence and number of cerebrospinal fluid (CSF) bands in distinguishing bacterial from aseptic meningitis among children with CSF pleocytosis...
  19. ncbi Development and validation of a multivariable predictive model to distinguish bacterial from aseptic meningitis in children in the post-Haemophilus influenzae era
    Lise E Nigrovic
    Department of Medicine, Children's Hospital and Harvard Medical School, Boston, Massachusetts 02115, USA
    Pediatrics 110:712-9. 2002
    ..CONCLUSIONS: The BMS accurately identifies children at low (BMS = 0) or high (BMS > or =2) risk of bacterial meningitis. Outpatient management may be considered for children in the low-risk group...
  20. ncbi Use of population health data to refine diagnostic decision-making for pertussis
    Andrew M Fine
    Division of Emergency Medicine, Children s Hospital Boston and Department of Pediatrics, Harvard Medical School, Boston, Massachusetts 02115, USA
    J Am Med Inform Assoc 17:85-90. 2010
    ..To improve identification of pertussis cases by developing a decision model that incorporates recent, local, population-level disease incidence...
  21. ncbi Linking surveillance to action: incorporation of real-time regional data into a medical decision rule
    Andrew M Fine
    Division of Emergency Medicine, Children s Hospital Boston, 300 Longwood Avenue, Boston, MA 02115, USA
    J Am Med Inform Assoc 14:206-11. 2007
    ..We incorporate data about recent local trends in meningitis epidemiology into a prediction model differentiating aseptic from bacterial meningitis...
  22. ncbi Impact of in-hospital enteroviral polymerase chain reaction testing on the clinical management of children with meningitis
    Todd W Lyons
    Department of Pediatrics, Boston Children s Hospital, Harvard Medical School, Boston, MA, USA
    J Hosp Med 7:517-20. 2012
    ..Enteroviral meningitis is a common cause of meningitis in children which requires only supportive care...
  23. ncbi Treatment complications in children with lyme meningitis
    Amy D Thompson
    Division of Emergency Medicine, Department of Pediatrics, Nemours, Alfred I duPont Hospital for Children, Jefferson Medical College, Wilmington, DE, USA
    Pediatr Infect Dis J 31:1032-5. 2012
    ..The rate and type of treatment complications in children treated for Lyme meningitis have not been described...
  24. ncbi Validation of a clinical prediction rule to distinguish Lyme meningitis from aseptic meningitis
    Keri A Cohn
    Division of Emergency Medicine, Children s Hospital and Harvard Medical School, Boston 300 Longwood Ave, Boston, MA 02115, USA
    Pediatrics 129:e46-53. 2012
    ..The goal of this study was to test the performance of the Rule of 7's in a multicenter cohort of children with CSF pleocytosis...
  25. ncbi Factors associated with the use of cervical spine computed tomography imaging in pediatric trauma patients
    Rebekah Mannix
    Division of Emergency Medicine, Department of Medicine, Children s Hospital Boston, MA, USA
    Acad Emerg Med 18:905-11. 2011
    ....
  26. ncbi Cerebrospinal latex agglutination fails to contribute to the microbiologic diagnosis of pretreated children with meningitis
    Lise E Nigrovic
    Division of Emergency Medicine, Children's Hospital, Boston, MA, USA
    Pediatr Infect Dis J 23:786-8. 2004
    ..Clinical decision-making algorithms for the management of pretreated patients at risk for bacterial meningitis should not include latex agglutination testing...
  27. ncbi Pediatric traumatic brain injury and radiation risks: a clinical decision analysis
    Kara E Hennelly
    Division of Emergency Medicine, Children s Hospital Boston, Boston, MA 02115, USA
    J Pediatr 162:392-7. 2013
    ....
  28. ncbi The prevalence of traumatic brain injuries after minor blunt head trauma in children with ventricular shunts
    Lise E Nigrovic
    Division of Emergency Medicine, Boston Children s Hospital, Harvard Medical School, Boston, MA, USA
    Ann Emerg Med 61:389-93. 2013
    ..We compare the prevalence of clinically important traumatic brain injuries and the use of cranial computed tomography (CT) in children with minor blunt head trauma with and without ventricular shunts...
  29. ncbi Factors associated with cervical spine injury in children after blunt trauma
    Julie C Leonard
    Department of Pediatrics, Division of Emergency Medicine, School of Medicine, Washington University in St Louis, St Louis Children s Hospital, One Children s Place, St Louis, MO 63110, USA
    Ann Emerg Med 58:145-55. 2011
    ..The purpose of our study is to identify risk factors associated with cervical spine injury in children after blunt trauma...
  30. ncbi Predictors of ventricular shunt infection among children presenting to a pediatric emergency department
    Elisabeth Ashley Rogers
    Department of Emergency Medicine, University of Virginia, Charlottesville, VA 22908, USA
    Pediatr Emerg Care 28:405-9. 2012
    ....
  31. ncbi Extreme thrombocytosis predicts Kawasaki disease in infants
    Lise E Nigrovic
    Division of Emergency Medicine, Children's Hospital Boston, Boston, MA 02115, USA
    Clin Pediatr (Phila) 45:446-52. 2006
    ..Because many infants present atypically, Kawasaki disease should be considered in all children of 1 year or less with prolonged fever, extreme elevation of the platelet count, and no compelling alternative diagnosis...
  32. ncbi Distinguishing lyme from septic knee monoarthritis in lyme disease-endemic areas
    Julia K Deanehan
    Division of Emergency Medicine, Boston Children s Hospital andHarvard Medical School, Boston, MA 02115, USA
    Pediatrics 131:e695-701. 2013
    ..Because Lyme and septic arthritis may present similarly, we sought to identify children with knee monoarthritis at low risk for septic arthritis who may not require arthrocentesis...
  33. ncbi Patients with juvenile psoriatic arthritis comprise two distinct populations
    Matthew L Stoll
    Children's Hospital Boston, Harvard Medical School, Massachusetts 02115, USA
    Arthritis Rheum 54:3564-72. 2006
    ..Although the pathophysiologic correlate of this finding remains undefined, future studies should avoid the assumption that PsA in childhood constitutes a single etiologic entity...