Lise E Nigrovic

Summary

Affiliation: Harvard University
Country: USA

Publications

  1. doi request reprint Nurse and physician agreement in the assessment of minor blunt head trauma
    Lise E Nigrovic
    Division of Emergency Medicine, Boston Children s Hospital, Boston, MA, USA
    Pediatrics 132:e689-94. 2013
  2. doi request reprint Aseptic meningitis
    Lise E Nigrovic
    Department of Medicine, Children s Hospital Boston and Harvard Medical School, Boston, MA, USA Electronic address
    Handb Clin Neurol 112:1153-6. 2013
  3. doi request reprint Trends in the management of viral meningitis at United States children's hospitals
    Lise E Nigrovic
    Division of Emergency Medicine, Department of Medicine, Boston Children s Hospital and Harvard Medical School, Boston, Massachusetts 02115, USA
    Pediatrics 131:670-6. 2013
  4. doi request reprint Meta-analysis of bacterial meningitis score validation studies
    Lise E Nigrovic
    Division of Emergency Medicine, Department of Pediatrics, Children s Hospital Boston and Harvard Medical School, 300 Longwood Avenue, Boston, MA 02115, USA
    Arch Dis Child 97:799-805. 2012
  5. doi request reprint Utility of plain radiographs in detecting traumatic injuries of the cervical spine in children
    Lise E Nigrovic
    Division of Emergency Medicine, Children s Hospital Boston and Harvard Medical School, Boston, MA 02115, USA
    Pediatr Emerg Care 28:426-32. 2012
  6. doi request reprint Prevalence of clinically important traumatic brain injuries in children with minor blunt head trauma and isolated severe injury mechanisms
    Lise E Nigrovic
    Division of Emergency Medicine, Children s Hospital, Boston, 300 Longwood Ave, Boston, MA 02115, USA
    Arch Pediatr Adolesc Med 166:356-61. 2012
  7. doi request reprint Correction of cerebrospinal fluid protein for the presence of red blood cells in children with a traumatic lumbar puncture
    Lise E Nigrovic
    Division of Emergency Medicine, Department of Pediatrics, Children s Hospital Boston and Harvard Medical School, Boston, MA 02115, USA
    J Pediatr 159:158-9. 2011
  8. doi request reprint The effect of observation on cranial computed tomography utilization for children after blunt head trauma
    Lise E Nigrovic
    Division of Emergency Medicine, Children s Hospital Boston, Boston, Boston, MA 02115, USA
    Pediatrics 127:1067-73. 2011
  9. doi request reprint Cerebrospinal fluid pleocytosis in children in the era of bacterial conjugate vaccines: distinguishing the child with bacterial and aseptic meningitis
    Lise E Nigrovic
    Division of Emergency Medicine, Children s Hospital Boston and Harvard Medical School, Boston, MA 02115, USA
    Pediatr Emerg Care 25:112-7; quiz 118-20. 2009
  10. doi request reprint Clinical predictors of Lyme disease among children with a peripheral facial palsy at an emergency department in a Lyme disease-endemic area
    Lise E Nigrovic
    Division of Emergency Medicine, Children s Hospital Boston, Boston, Massachusetts 02115, USA
    Pediatrics 122:e1080-5. 2008

Detail Information

Publications42

  1. doi request reprint Nurse and physician agreement in the assessment of minor blunt head trauma
    Lise E Nigrovic
    Division of Emergency Medicine, Boston Children s Hospital, Boston, MA, USA
    Pediatrics 132:e689-94. 2013
    ..We measured the agreement between the registered nurse (RN) and physician (MD) assessments...
  2. doi request reprint Aseptic meningitis
    Lise E Nigrovic
    Department of Medicine, Children s Hospital Boston and Harvard Medical School, Boston, MA, USA Electronic address
    Handb Clin Neurol 112:1153-6. 2013
    ....
  3. doi request reprint Trends in the management of viral meningitis at United States children's hospitals
    Lise E Nigrovic
    Division of Emergency Medicine, Department of Medicine, Boston Children s Hospital and Harvard Medical School, Boston, Massachusetts 02115, USA
    Pediatrics 131:670-6. 2013
    ..To determine trends in the diagnosis and management of children with viral meningitis at US children's hospitals...
  4. doi request reprint Meta-analysis of bacterial meningitis score validation studies
    Lise E Nigrovic
    Division of Emergency Medicine, Department of Pediatrics, Children s Hospital Boston and Harvard Medical School, 300 Longwood Avenue, Boston, MA 02115, USA
    Arch Dis Child 97:799-805. 2012
    ..The study objective of the present work was to calculate the performance of the Bacterial Meningitis Score by performing a meta-analysis of all published validation studies...
  5. doi request reprint Utility of plain radiographs in detecting traumatic injuries of the cervical spine in children
    Lise E Nigrovic
    Division of Emergency Medicine, Children s Hospital Boston and Harvard Medical School, Boston, MA 02115, USA
    Pediatr Emerg Care 28:426-32. 2012
    ..The objective of this study was to estimate the sensitivity of plain radiographs in identifying bony or ligamentous cervical spine injury in children...
  6. doi request reprint Prevalence of clinically important traumatic brain injuries in children with minor blunt head trauma and isolated severe injury mechanisms
    Lise E Nigrovic
    Division of Emergency Medicine, Children s Hospital, Boston, 300 Longwood Ave, Boston, MA 02115, USA
    Arch Pediatr Adolesc Med 166:356-61. 2012
    ....
  7. doi request reprint Correction of cerebrospinal fluid protein for the presence of red blood cells in children with a traumatic lumbar puncture
    Lise E Nigrovic
    Division of Emergency Medicine, Department of Pediatrics, Children s Hospital Boston and Harvard Medical School, Boston, MA 02115, USA
    J Pediatr 159:158-9. 2011
    ..For every 1000 cell increase in CSF red blood cells per mm(3), CSF protein increases by 1.1 mg/dL (95% CI, 0.9-1.1 mg/dL)...
  8. doi request reprint The effect of observation on cranial computed tomography utilization for children after blunt head trauma
    Lise E Nigrovic
    Division of Emergency Medicine, Children s Hospital Boston, Boston, Boston, MA 02115, USA
    Pediatrics 127:1067-73. 2011
    ..Children with minor blunt head trauma often are observed in the emergency department before a decision is made regarding computed tomography use. We studied the impact of this clinical strategy on computed tomography use and outcomes...
  9. doi request reprint Cerebrospinal fluid pleocytosis in children in the era of bacterial conjugate vaccines: distinguishing the child with bacterial and aseptic meningitis
    Lise E Nigrovic
    Division of Emergency Medicine, Children s Hospital Boston and Harvard Medical School, Boston, MA 02115, USA
    Pediatr Emerg Care 25:112-7; quiz 118-20. 2009
    ....
  10. doi request reprint Clinical predictors of Lyme disease among children with a peripheral facial palsy at an emergency department in a Lyme disease-endemic area
    Lise E Nigrovic
    Division of Emergency Medicine, Children s Hospital Boston, Boston, Massachusetts 02115, USA
    Pediatrics 122:e1080-5. 2008
    ..Although Lyme disease can cause peripheral facial palsy in Lyme disease-endemic areas, diagnostic predictors in children have not been described...
  11. doi request reprint Effect of antibiotic pretreatment on cerebrospinal fluid profiles of children with bacterial meningitis
    Lise E Nigrovic
    Children s Hospital Boston and Harvard Medical School, Boston, MA 02115, USA
    Pediatrics 122:726-30. 2008
    ..The goal of this study was to evaluate the effect of antibiotic administration before lumbar puncture on cerebrospinal fluid profiles in children with bacterial meningitis...
  12. doi request reprint Tularemia
    Lise E Nigrovic
    Division of Emergency Medicine, Children s Hospital, Boston, 300 Longwood Avenue, Boston, MA 02115, USA
    Infect Dis Clin North Am 22:489-504, ix. 2008
    ..Recent world events have led to a new recognition of F tularensis as a viable agent of bioterrorism, which has sparked a renewed focus on this pathogen...
  13. ncbi request reprint Clinical prediction rule for identifying children with cerebrospinal fluid pleocytosis at very low risk of bacterial meningitis
    Lise E Nigrovic
    Department of Medicine, Children s Hospital Boston and Harvard Medical School, Boston, Mass 02115, USA
    JAMA 297:52-60. 2007
    ....
  14. ncbi request reprint Risk factors for traumatic or unsuccessful lumbar punctures in children
    Lise E Nigrovic
    Division of Emergency Medicine, Children s Hospital and Harvard Medical School, Boston, MA 02115, USA
    Ann Emerg Med 49:762-71. 2007
    ..We sought to determine patient, physician, and procedural factors associated with traumatic and unsuccessful lumbar punctures in children...
  15. ncbi request reprint Lumbar puncture success rate is not influenced by family-member presence
    Lise E Nigrovic
    Division of Emergency Medicine, Children s Hospital Boston and Harvard Medical School, Boston, MA 02115, USA
    Pediatrics 120:e777-82. 2007
    ..However, family presence might also affect clinicians' stress and anxiety, with uncertain consequences for procedural success...
  16. ncbi request reprint Cerebrospinal fluid xanthochromia in newborns is related to maternal labor before delivery
    Lise E Nigrovic
    Division of Emergency Medicine, Children s Hospital Boston, 300 Longwood Ave, Boston, MA 02115, USA
    Pediatrics 120:e1212-6. 2007
    ..The purpose of this work was to investigate whether xanthochromia in newborns is related to maternal labor before delivery...
  17. doi request reprint Children with bacterial meningitis presenting to the emergency department during the pneumococcal conjugate vaccine era
    Lise E Nigrovic
    Division of Emergency Medicine, Children s Hospital, Boston, MA, USA
    Acad Emerg Med 15:522-8. 2008
    ..The epidemiology of bacterial meningitis in children in the era of widespread heptavalent conjugate pneumococcal vaccination (PCV7) is unknown...
  18. pmc Integrating spatial epidemiology into a decision model for evaluation of facial palsy in children
    Andrew M Fine
    Division of Emergency Medicine, Children s Hospital Boston, Boston, MA 02115, USA
    Arch Pediatr Adolesc Med 165:61-7. 2011
    ..To develop a novel diagnostic algorithm for Lyme disease among children with facial palsy by integrating public health surveillance data with traditional clinical predictors...
  19. doi request reprint Enteroviral testing and length of hospital stay for children evaluated for lyme meningitis
    Lise E Nigrovic
    Division of Emergency Medicine, Boston Children s Hospital, Boston, MA 02115, USA
    J Emerg Med 44:1196-200. 2013
    ..Although Lyme serology takes several days, an enteroviral polymerase chain reaction (EV PCR) test takes only a few hours to return results...
  20. doi request reprint Diagnostic value of immature neutrophils (bands) in the cerebrospinal fluid of children with cerebrospinal fluid pleocytosis
    John T Kanegaye
    Division of Emergency Medicine, Rady Children s Hospital San Diego, 3020 Children s Way, MC 5075, San Diego, CA 92123, USA
    Pediatrics 123:e967-71. 2009
    ..We evaluated the diagnostic utility of the presence and number of cerebrospinal fluid (CSF) bands in distinguishing bacterial from aseptic meningitis among children with CSF pleocytosis...
  21. ncbi request reprint Development and validation of a multivariable predictive model to distinguish bacterial from aseptic meningitis in children in the post-Haemophilus influenzae era
    Lise E Nigrovic
    Department of Medicine, Children s Hospital and Harvard Medical School, Boston, Massachusetts 02115, USA
    Pediatrics 110:712-9. 2002
    ..Children with meningitis are routinely admitted to the hospital and administered broad-spectrum antibiotics pending culture results because distinguishing bacterial meningitis from aseptic meningitis is often difficult...
  22. doi request reprint Spinal cord injury without radiologic abnormality in children imaged with magnetic resonance imaging
    Prashant Mahajan
    From the Division of Emergency Medicine P M, Department of Pediatrics, Children s Hospital of Michigan and Wayne State University School of Medicine, Detroit and Departments of Emergency Medicine A J R and Pediatrics A J R, University of Michigan Medical Center and University of Michigan School of Medicine, Ann Arbor, Michigan Department of Pediatrics D M J, J C L, St Louis Children s Hospital D M J, J R L, J C L and Washington University School of Medicine, St Louis, Missouri Department of Pediatrics C S O, University of Utah School of Medicine, Salt Lake City, Utah Department of Neurosurgery J R L, Division of Emergency Medicine L E N, Boston Children s Hospital and Harvard Medical School, Boston, Massachusetts Departments of Emergency Medicine N K and Pediatrics N K, University of California, Davis, School of Medicine, Davis, California
    J Trauma Acute Care Surg 75:843-7. 2013
    ..This study aimed to compare children diagnosed with cervical spinal cord injury without radiographic abnormality (SCIWORA) relative to whether there is evidence of cervical spinal cord abnormalities on magnetic resonance imaging (MRI)...
  23. pmc Use of population health data to refine diagnostic decision-making for pertussis
    Andrew M Fine
    Division of Emergency Medicine, Children s Hospital Boston and Department of Pediatrics, Harvard Medical School, Boston, Massachusetts 02115, USA
    J Am Med Inform Assoc 17:85-90. 2010
    ..To improve identification of pertussis cases by developing a decision model that incorporates recent, local, population-level disease incidence...
  24. pmc Linking surveillance to action: incorporation of real-time regional data into a medical decision rule
    Andrew M Fine
    Division of Emergency Medicine, Children s Hospital Boston, 300 Longwood Avenue, Boston, MA 02115, USA
    J Am Med Inform Assoc 14:206-11. 2007
    ..We incorporate data about recent local trends in meningitis epidemiology into a prediction model differentiating aseptic from bacterial meningitis...
  25. doi request reprint The prevalence of traumatic brain injuries after minor blunt head trauma in children with ventricular shunts
    Lise E Nigrovic
    Division of Emergency Medicine, Boston Children s Hospital, Harvard Medical School, Boston, MA, USA
    Ann Emerg Med 61:389-93. 2013
    ..We compare the prevalence of clinically important traumatic brain injuries and the use of cranial computed tomography (CT) in children with minor blunt head trauma with and without ventricular shunts...
  26. doi request reprint Isolated skull fractures: trends in management in US pediatric emergency departments
    Rebekah Mannix
    Division of Emergency Medicine, Department of Medicine, Boston Children s Hospital, and Harvard Medical School, Harvard University, Boston, MA Electronic address
    Ann Emerg Med 62:327-31. 2013
    ..We seek to evaluate current practice for children presenting to the emergency department (ED) for isolated skull fractures in US children's hospitals...
  27. doi request reprint Impact of in-hospital enteroviral polymerase chain reaction testing on the clinical management of children with meningitis
    Todd W Lyons
    Department of Pediatrics, Boston Children s Hospital, Harvard Medical School, Boston, MA, USA
    J Hosp Med 7:517-20. 2012
    ..Enteroviral meningitis is a common cause of meningitis in children which requires only supportive care...
  28. ncbi request reprint Treatment complications in children with lyme meningitis
    Amy D Thompson
    Division of Emergency Medicine, Department of Pediatrics, Nemours, Alfred I duPont Hospital for Children, Jefferson Medical College, Wilmington, DE, USA
    Pediatr Infect Dis J 31:1032-5. 2012
    ..The rate and type of treatment complications in children treated for Lyme meningitis have not been described...
  29. doi request reprint Validation of a clinical prediction rule to distinguish Lyme meningitis from aseptic meningitis
    Keri A Cohn
    Division of Emergency Medicine, Children s Hospital and Harvard Medical School, Boston 300 Longwood Ave, Boston, MA 02115, USA
    Pediatrics 129:e46-53. 2012
    ..The goal of this study was to test the performance of the Rule of 7's in a multicenter cohort of children with CSF pleocytosis...
  30. doi request reprint Synovial fluid findings in children with knee monoarthritis in lyme disease endemic areas
    Julia K Deanehan
    From the Division of Emergency Medicine, Boston Children s Hospital Harvard Medical School, Boston, MA Johns Hopkins Medical School and Johns Hopkins Children s Center Baltimore, MD Division of Immunology, Boston Children s Hospital Division of Rheumatology, Immunology and Allergy, Brigham and Women s Hospital, Boston, MA Department of Orthopedics and Rehabilitation, Yale University School of Medicine, New Haven and Elite Sports Medicine, Connecticut Children s Medical Center, Farmington, CT and University of Melbourne School of Medicine, Melbourne, Australia
    Pediatr Emerg Care 30:16-9. 2014
    ..We sought to determine whether synovial fluid cell counts alone can discriminate between Lyme, septic, and other inflammatory arthritis...
  31. pmc Factors associated with the use of cervical spine computed tomography imaging in pediatric trauma patients
    Rebekah Mannix
    Division of Emergency Medicine, Department of Medicine, Children s Hospital Boston, MA, USA
    Acad Emerg Med 18:905-11. 2011
    ....
  32. ncbi request reprint Cerebrospinal latex agglutination fails to contribute to the microbiologic diagnosis of pretreated children with meningitis
    Lise E Nigrovic
    Division of Emergency Medicine, Children s Hospital, Boston, MA, USA
    Pediatr Infect Dis J 23:786-8. 2004
    ..Clinical decision-making algorithms for the management of pretreated patients at risk for bacterial meningitis should not include latex agglutination testing...
  33. doi request reprint Factors associated with cervical spine injury in children after blunt trauma
    Julie C Leonard
    Department of Pediatrics, Division of Emergency Medicine, School of Medicine, Washington University in St Louis, St Louis Children s Hospital, One Children s Place, St Louis, MO 63110, USA
    Ann Emerg Med 58:145-55. 2011
    ..The purpose of our study is to identify risk factors associated with cervical spine injury in children after blunt trauma...
  34. doi request reprint Pediatric traumatic brain injury and radiation risks: a clinical decision analysis
    Kara E Hennelly
    Division of Emergency Medicine, Children s Hospital Boston, Boston, MA 02115, USA
    J Pediatr 162:392-7. 2013
    ....
  35. doi request reprint The bacterial meningitis score to distinguish bacterial from aseptic meningitis in children from Sao Paulo, Brazil
    Eduardo Mekitarian Filho
    From the Pediatric Emergency Department, University of Sao Paulo, Sao Paulo, Brazil and Division of Emergency Medicine, Boston Children s Hospital, Boston, MA
    Pediatr Infect Dis J 32:1026-9. 2013
    ..Addition of cerebrospinal fluid lactate to the score did not improve clinical prediction rule performance. ..
  36. doi request reprint Effect of the duration of emergency department observation on computed tomography use in children with minor blunt head trauma
    Deborah Schonfeld
    Division of Emergency Medicine, Boston Children s Hospital, Boston, MA
    Ann Emerg Med 62:597-603. 2013
    ..We determine the effect of the duration of emergency department (ED) observation on computed tomography (CT) rate for children with minor blunt head trauma...
  37. doi request reprint Characteristics of the pediatric patients treated by the pediatric emergency care applied research network's affiliated EMS agencies
    E Brooke Lerner
    From the Department of Emergency Medicine, Medical College of Wisconsin, Milwaukee, Wisconsin EBL, Department of Pediatrics, Columbia University College of Physicians and Surgeons, The New York Presbyterian Morgan Stanley Children s Hospital, New York, New York PSD, MK, Departments of Pediatrics and Emergency Medicine, George Washington School of Medicine, Children s National Medical Center, Washington, DC KB, Department of Pediatrics, Feinberg School of Medicine, Northwestern University, Ann and Robert H Lurie Children s Hospital of Chicago, Chicago, Illinois SF, Department of Pediatrics, Washington University School of Medicine, St Louis Children s Hospital, St Louis, Missouri JL, Departments of Emergency Medicine, University of Michigan and Hurley Medical Center, Flint, Michigan DB, Department of Pediatric Emergency Medicine, Cincinnati Children s Hospital Medical Center, Cincinnati, Ohio LB, Division of Emergency Medicine, Michigan State University College of Human Medicine, Helen DeVos Children s Hospital, Grand Rapids, Michigan JDH, Department of Pediatrics, Division of Emergency Medicine, State University of New York at Buffalo, Department of Chemistry
    Prehosp Emerg Care 18:52-9. 2014
    ..To describe pediatric patients transported by the Pediatric Emergency Care Applied Research Network's (PECARN's) affiliated emergency medical service (EMS) agencies and the process of submitting and aggregating data from diverse agencies...
  38. doi request reprint Distinguishing Lyme from septic knee monoarthritis in Lyme disease-endemic areas
    Julia K Deanehan
    Division of Emergency Medicine, Boston Children s Hospital andHarvard Medical School, Boston, MA 02115, USA
    Pediatrics 131:e695-701. 2013
    ..Because Lyme and septic arthritis may present similarly, we sought to identify children with knee monoarthritis at low risk for septic arthritis who may not require arthrocentesis...
  39. doi request reprint Predictors of ventricular shunt infection among children presenting to a pediatric emergency department
    Elisabeth Ashley Rogers
    Department of Emergency Medicine, University of Virginia, Charlottesville, VA 22908, USA
    Pediatr Emerg Care 28:405-9. 2012
    ....
  40. ncbi request reprint Extreme thrombocytosis predicts Kawasaki disease in infants
    Lise E Nigrovic
    Division of Emergency Medicine, Children s Hospital Boston, Boston, MA 02115, USA
    Clin Pediatr (Phila) 45:446-52. 2006
    ..Because many infants present atypically, Kawasaki disease should be considered in all children of 1 year or less with prolonged fever, extreme elevation of the platelet count, and no compelling alternative diagnosis...
  41. doi request reprint Validation of anaphylaxis in the Food and Drug Administration's Mini-Sentinel
    Kathleen E Walsh
    Meyers Primary Care Institute, Worcester, MA, USA
    Pharmacoepidemiol Drug Saf 22:1205-13. 2013
    ..Previously published PPVs for anaphylaxis using International Classification of Diseases, ninth revision, Clinical Modification (ICD-9-CM) codes range from 52% to 57%...
  42. ncbi request reprint Patients with juvenile psoriatic arthritis comprise two distinct populations
    Matthew L Stoll
    Children s Hospital Boston, Harvard Medical School, Massachusetts 02115, USA
    Arthritis Rheum 54:3564-72. 2006
    ..Psoriatic arthritis (PsA) in children is clinically heterogeneous. We examined a large population of children with juvenile PsA for evidence of phenotypic clustering that could suggest the presence of distinct clinical entities...