Claude Nicolau

Summary

Affiliation: Harvard University
Country: USA

Publications

  1. pmc A liposome-based therapeutic vaccine against beta -amyloid plaques on the pancreas of transgenic NORBA mice
    Claude Nicolau
    Ecole Superieure de Biotechnologie de Strasbourg, Universite Louis Pasteur, 67091 Strasbourg, France
    Proc Natl Acad Sci U S A 99:2332-7. 2002
  2. pmc Liposomal vaccines with conformation-specific amyloid peptide antigens define immune response and efficacy in APP transgenic mice
    Andreas Muhs
    AC Immune, PSE B, Ecole Polytechnique Federale de Lausanne, 1015 Lausanne, Switzerland
    Proc Natl Acad Sci U S A 104:9810-5. 2007
  3. ncbi request reprint Induction of autoantibodies to murine P-glycoprotein: consequences on drug sensitivity in MDR cancer cells and on the expression of mdr genes in organs
    Laura Perrin
    Laboratory of Biochemistry, EA 3796, IFR 53 Biomolecules, 51 Rue Cognac Jay, 51096 Reims Cedex, France
    Biochem Biophys Res Commun 358:325-30. 2007
  4. ncbi request reprint Immunization with liposome-anchored pegylated peptides modulates doxorubicin sensitivity in P-glycoprotein-expressing P388 cells
    Gregory Gatouillat
    Laboratory of Biochemistry, IFR53, Faculty of Pharmacy, 51 rue Cognacq Jay, 51096 Reims Cedex, France
    Cancer Lett 257:165-71. 2007

Collaborators

  • Gregory Gatouillat
  • Laura Perrin
  • Johann Odot
  • Andreas Muhs
  • Pierre François Tosi
  • Claudie Madoulet
  • Emilie Balasse
  • David T Hickman
  • Andrea Pfeifer
  • Marie Catherine Weingertner
  • Ingrid Van der Auwera
  • Maria Pihlgren
  • Detlev Riesner
  • María Pilar López-Deber
  • Nathalie Chuard
  • Masae Sugawara
  • Valérie Giriens
  • Ruth Greferath
  • Fred Van Leuven
  • Luitgard Nagel-Steger
  • Roscoe O Brady
  • Burkhard Bechinger
  • Nadine Kolonko
  • Carine Meerschman

Detail Information

Publications4

  1. pmc A liposome-based therapeutic vaccine against beta -amyloid plaques on the pancreas of transgenic NORBA mice
    Claude Nicolau
    Ecole Superieure de Biotechnologie de Strasbourg, Universite Louis Pasteur, 67091 Strasbourg, France
    Proc Natl Acad Sci U S A 99:2332-7. 2002
    ..Possible implications for the therapy of Alzheimer's disease are discussed...
  2. pmc Liposomal vaccines with conformation-specific amyloid peptide antigens define immune response and efficacy in APP transgenic mice
    Andreas Muhs
    AC Immune, PSE B, Ecole Polytechnique Federale de Lausanne, 1015 Lausanne, Switzerland
    Proc Natl Acad Sci U S A 104:9810-5. 2007
    ..This finding supports the hypothesis that Alzheimer's disease is a "conformational" disease, implying that antibodies against amyloid sequences in the beta-sheet conformation are preferred as potential therapeutic agents...
  3. ncbi request reprint Induction of autoantibodies to murine P-glycoprotein: consequences on drug sensitivity in MDR cancer cells and on the expression of mdr genes in organs
    Laura Perrin
    Laboratory of Biochemistry, EA 3796, IFR 53 Biomolecules, 51 Rue Cognac Jay, 51096 Reims Cedex, France
    Biochem Biophys Res Commun 358:325-30. 2007
    ..These results suggest that the induction of autoantibodies to P-gp is a safe strategy to overcome MDR in cancer chemotherapy...
  4. ncbi request reprint Immunization with liposome-anchored pegylated peptides modulates doxorubicin sensitivity in P-glycoprotein-expressing P388 cells
    Gregory Gatouillat
    Laboratory of Biochemistry, IFR53, Faculty of Pharmacy, 51 rue Cognacq Jay, 51096 Reims Cedex, France
    Cancer Lett 257:165-71. 2007
    ..Overall, these results suggest that this approach can modulate Pgp activity by blocking drug efflux and may have clinical relevance as an alternative strategy to toxic chemosensitizers in drug-resistant cancer therapy...