Daniel J Needleman

Summary

Affiliation: Harvard University
Country: USA

Publications

  1. doi request reprint Plasmid segregation: is a total understanding within reach?
    Daniel J Needleman
    Department of Systems Biology, Harvard Medical School, Boston, Massachusetts 02115, USA
    Curr Biol 18:R212-4. 2008
  2. pmc Pin-hole array correlation imaging: highly parallel fluorescence correlation spectroscopy
    Daniel J Needleman
    Department of Systems Biology, Harvard Medical School, Boston, Massachusetts, USA
    Biophys J 96:5050-9. 2009
  3. doi request reprint Cellular allometry: the spindle in development and inheritance
    Daniel J Needleman
    Harvard University, 52 Oxford Street, Room 365 10, Cambridge, MA 02138, USA
    Curr Biol 19:R846-7. 2009
  4. pmc Fast microtubule dynamics in meiotic spindles measured by single molecule imaging: evidence that the spindle environment does not stabilize microtubules
    Daniel J Needleman
    School of Engineering and Applied Sciences, Molecular and Cellular Biology, Harvard University, Cambridge, MA 02138, USA
    Mol Biol Cell 21:323-33. 2010
  5. doi request reprint Mitosis: taking the measure of spindle length
    Daniel J Needleman
    Harvard University, Cambridge, MA 02138, USA
    Curr Biol 20:R359-60. 2010
  6. pmc Evidence for an upper limit to mitotic spindle length
    Martin Wühr
    Department of Systems Biology, Harvard Medical School, Boston, Massachusetts 02115, USA
    Curr Biol 18:1256-61. 2008
  7. pmc How does a millimeter-sized cell find its center?
    Martin Wühr
    Department of Systems Biology, Harvard Medical School, 200 Longwood Avenue, Boston, MA 02115 USA
    Cell Cycle 8:1115-21. 2009

Detail Information

Publications7

  1. doi request reprint Plasmid segregation: is a total understanding within reach?
    Daniel J Needleman
    Department of Systems Biology, Harvard Medical School, Boston, Massachusetts 02115, USA
    Curr Biol 18:R212-4. 2008
    ..Recent in vitro and in vivo studies of the proteins responsible for the active partitioning of bacterial plasmids suggest that it will be possible to develop a quantitative, molecular understanding of this form of DNA segregation...
  2. pmc Pin-hole array correlation imaging: highly parallel fluorescence correlation spectroscopy
    Daniel J Needleman
    Department of Systems Biology, Harvard Medical School, Boston, Massachusetts, USA
    Biophys J 96:5050-9. 2009
    ....
  3. doi request reprint Cellular allometry: the spindle in development and inheritance
    Daniel J Needleman
    Harvard University, 52 Oxford Street, Room 365 10, Cambridge, MA 02138, USA
    Curr Biol 19:R846-7. 2009
    ..Recent studies have demonstrated a correlation between cell size and the behaviors of the cytoskeletal division machinery during embryogenesis, giving insight into how a core cellular process is modulated over the course of development...
  4. pmc Fast microtubule dynamics in meiotic spindles measured by single molecule imaging: evidence that the spindle environment does not stabilize microtubules
    Daniel J Needleman
    School of Engineering and Applied Sciences, Molecular and Cellular Biology, Harvard University, Cambridge, MA 02138, USA
    Mol Biol Cell 21:323-33. 2010
    ..It follows that the key to understanding spindle morphogenesis will be to elucidate how nucleation is spatially controlled...
  5. doi request reprint Mitosis: taking the measure of spindle length
    Daniel J Needleman
    Harvard University, Cambridge, MA 02138, USA
    Curr Biol 20:R359-60. 2010
    ..Recent studies have investigated the mechanisms responsible for setting spindle length - and how spindle length changes over the course of development...
  6. pmc Evidence for an upper limit to mitotic spindle length
    Martin Wühr
    Department of Systems Biology, Harvard Medical School, Boston, Massachusetts 02115, USA
    Curr Biol 18:1256-61. 2008
    ..We conclude that early mitotic spindle length in Xenopus laevis is uncoupled from cell length, reaching an upper bound determined by mechanisms that are intrinsic to the spindle...
  7. pmc How does a millimeter-sized cell find its center?
    Martin Wühr
    Department of Systems Biology, Harvard Medical School, 200 Longwood Avenue, Boston, MA 02115 USA
    Cell Cycle 8:1115-21. 2009
    ....