Ara Nazarian

Summary

Affiliation: Harvard University
Country: USA

Publications

  1. doi request reprint A biomechanical evaluation of all-inside 2-stitch meniscal repair devices with matched inside-out suture repair
    Arun J Ramappa
    Ara Nazarian, Center for Advanced Orthopaedic Studies, Department of Orthopaedic Surgery, Beth Israel Deaconess Medical Center, 330 Brookline Avenue, RN115, Boston, MA 02215
    Am J Sports Med 42:194-9. 2014
  2. pmc Preliminary evaluation of a robotic apparatus for the analysis of passive glenohumeral joint kinematics
    Claudio Rosso
    Orthopaedic Department, University Hospital Basel, University of Basel, Basel, Switzerland
    J Orthop Surg Res 8:24. 2013
  3. doi request reprint Tensile properties of rat femoral bone as functions of bone volume fraction, apparent density and volumetric bone mineral density
    Ara Nazarian
    Center for Advanced Orthopaedic Studies, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA, USA
    J Biomech 44:2482-8. 2011
  4. doi request reprint Bone volume fraction explains the variation in strength and stiffness of cancellous bone affected by metastatic cancer and osteoporosis
    Ara Nazarian
    Orthopedic Biomechanics Laboratory, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA
    Calcif Tissue Int 83:368-79. 2008
  5. doi request reprint Application of structural rigidity analysis to assess fidelity of healed fractures in rat femurs with critical defects
    Ara Nazarian
    Center for Advanced Orthopedic Studies, Beth Israel Deaconess Medical Center, Harvard Medical School, 330 Brookline Avenue, RN115, Boston, MA 02215, USA
    Calcif Tissue Int 86:397-403. 2010
  6. doi request reprint Functional dependence of cancellous bone shear properties on trabecular microstructure evaluated using time-lapsed micro-computed tomographic imaging and torsion testing
    Ara Nazarian
    Orthopedic Biomechanics Laboratory, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachusetts, USA
    J Orthop Res 27:1667-74. 2009
  7. doi request reprint Compressive axial mechanical properties of rat bone as functions of bone volume fraction, apparent density and micro-ct based mineral density
    Esther Cory
    Center for Advanced Orthopedic Studies, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA, USA
    J Biomech 43:953-60. 2010
  8. doi request reprint An improved method to assess torsional properties of rodent long bones
    Ara Nazarian
    Orthopedic Biomechanics Laboratory, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA 02215, USA
    J Biomech 42:1720-5. 2009
  9. doi request reprint Further improvements on the factors affecting bone mineral density measured by quantitative micro-computed tomography
    Vahid Entezari
    Center for Advanced Orthopedic Studies, Department of Orthopaedic Surgery, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA
    Bone 50:611-8. 2012
  10. ncbi request reprint The interaction of microstructure and volume fraction in predicting failure in cancellous bone
    Ara Nazarian
    Orthopedic Biomechanics Laboratory, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA, USA
    Bone 39:1196-202. 2006

Collaborators

Detail Information

Publications30

  1. doi request reprint A biomechanical evaluation of all-inside 2-stitch meniscal repair devices with matched inside-out suture repair
    Arun J Ramappa
    Ara Nazarian, Center for Advanced Orthopaedic Studies, Department of Orthopaedic Surgery, Beth Israel Deaconess Medical Center, 330 Brookline Avenue, RN115, Boston, MA 02215
    Am J Sports Med 42:194-9. 2014
    ..0 Hi-Fi, using an inside-out repair technique...
  2. pmc Preliminary evaluation of a robotic apparatus for the analysis of passive glenohumeral joint kinematics
    Claudio Rosso
    Orthopaedic Department, University Hospital Basel, University of Basel, Basel, Switzerland
    J Orthop Surg Res 8:24. 2013
    ..Similarly, most established techniques track shoulder motion discontinuously with limited accuracy...
  3. doi request reprint Tensile properties of rat femoral bone as functions of bone volume fraction, apparent density and volumetric bone mineral density
    Ara Nazarian
    Center for Advanced Orthopaedic Studies, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA, USA
    J Biomech 44:2482-8. 2011
    ..The relationships reported in this study can be used in the structural rigidity to provide a non-invasive method to assess the tensile behavior of bones affected by pathology and/or treatment options...
  4. doi request reprint Bone volume fraction explains the variation in strength and stiffness of cancellous bone affected by metastatic cancer and osteoporosis
    Ara Nazarian
    Orthopedic Biomechanics Laboratory, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA
    Calcif Tissue Int 83:368-79. 2008
    ....
  5. doi request reprint Application of structural rigidity analysis to assess fidelity of healed fractures in rat femurs with critical defects
    Ara Nazarian
    Center for Advanced Orthopedic Studies, Beth Israel Deaconess Medical Center, Harvard Medical School, 330 Brookline Avenue, RN115, Boston, MA 02215, USA
    Calcif Tissue Int 86:397-403. 2010
    ..These findings suggest considerable promise in the use of structural rigidity analysis of microCT data to accurately and quantitatively measure fracture-healing progression...
  6. doi request reprint Functional dependence of cancellous bone shear properties on trabecular microstructure evaluated using time-lapsed micro-computed tomographic imaging and torsion testing
    Ara Nazarian
    Orthopedic Biomechanics Laboratory, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachusetts, USA
    J Orthop Res 27:1667-74. 2009
    ....
  7. doi request reprint Compressive axial mechanical properties of rat bone as functions of bone volume fraction, apparent density and micro-ct based mineral density
    Esther Cory
    Center for Advanced Orthopedic Studies, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA, USA
    J Biomech 43:953-60. 2010
    ....
  8. doi request reprint An improved method to assess torsional properties of rodent long bones
    Ara Nazarian
    Orthopedic Biomechanics Laboratory, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA 02215, USA
    J Biomech 42:1720-5. 2009
    ..Coupled with the structural rigidity analysis technique introduced by the authors, the relationships reported here can provide a non-invasive tool to assess fracture risk in bones affected by pathologies and/or treatment options...
  9. doi request reprint Further improvements on the factors affecting bone mineral density measured by quantitative micro-computed tomography
    Vahid Entezari
    Center for Advanced Orthopedic Studies, Department of Orthopaedic Surgery, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA
    Bone 50:611-8. 2012
    ..horizontal orientation at the center of the reconstruction space (P value<0.001). We conclude that energy, resolution and post processing correction factor are significant predictors of the observed mineral density in μCT...
  10. ncbi request reprint The interaction of microstructure and volume fraction in predicting failure in cancellous bone
    Ara Nazarian
    Orthopedic Biomechanics Laboratory, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA, USA
    Bone 39:1196-202. 2006
    ....
  11. doi request reprint Quantitative micro-computed tomography: a non-invasive method to assess equivalent bone mineral density
    Ara Nazarian
    Orthopedic Biomechanics Laboratory, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA, 02215, USA
    Bone 43:302-11. 2008
    ..However, as with any liquid calibration phantom, they are susceptible to degradation over time...
  12. doi request reprint Non-invasive assessment of failure torque in rat bones with simulated lytic lesions using computed tomography based structural rigidity analysis
    Vahid Entezari
    Center for Advanced Orthopaedic Studies, Beth Israel Deaconess Medical Center, Harvard Medical School, 330 Brookline Avenue, RN115, Boston, MA 02215, USA
    J Biomech 44:552-6. 2011
    ..Structural rigidity analysis can provide more accurate predictions on maximal torque to mechanical failure than dual energy X-ray absorptiometry based on bone mineral density...
  13. doi request reprint The effect of simulated scapular winging on glenohumeral joint translations
    Andreas M Mueller
    Center for Advanced Orthopaedic Studies, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA, USA
    J Shoulder Elbow Surg 22:986-92. 2013
    ..In this study, we aim to test whether scapular winging results in a significant change in glenohumeral translation in the initial phase of the throwing motion...
  14. doi request reprint A prospective study of radiographic manifestations in Hutchinson-Gilford progeria syndrome
    Robert H Cleveland
    Pediatric Radiology, Children s Hospital Boston, Harvard Medical School, Boston, MA 02115, USA
    Pediatr Radiol 42:1089-98. 2012
    ..There has been no comprehensive prospective study describing the skeletal abnormalities associated with progeria...
  15. pmc Clinical trial of a farnesyltransferase inhibitor in children with Hutchinson-Gilford progeria syndrome
    Leslie B Gordon
    Department of Anesthesia, Boston Children s Hospital and Harvard Medical School, Boston, MA 02115, USA
    Proc Natl Acad Sci U S A 109:16666-71. 2012
    ..Results from this clinical treatment trial for children with HGPS provide preliminary evidence that lonafarnib may improve vascular stiffness, bone structure, and audiological status...
  16. pmc Quantitative (31)P NMR spectroscopy and (1)H MRI measurements of bone mineral and matrix density differentiate metabolic bone diseases in rat models
    Haihui Cao
    Department of Orthopaedic Surgery, Children s Hospital, Boston, MA 02115, USA
    Bone 46:1582-90. 2010
    ..These results demonstrate that the combined (31)P NMR/WASPI method is capable of discerning the difference in EBM between animals with osteoporosis and those with impaired bone mineralization...
  17. ncbi request reprint Densitometric, morphometric and mechanical distributions in the human proximal femur
    Ara Nazarian
    Orthopedic Biomechanics Laboratory, Beth Israel Deaconess Medical Center, Harvard Medical School, 330 Brookline Avenue, RN115, Boston, MA 02215, USA
    J Biomech 40:2573-9. 2007
    ....
  18. pmc Microstructural, densitometric and metabolic variations in bones from rats with normal or altered skeletal States
    Andrew N Luu
    Center for Advanced Orthopaedic Studies, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachusetts, United States of America School of Medicine, Tufts University, Boston, Massachusetts, United States of America
    PLoS ONE 8:e82709. 2013
    ..The aim of this study was to assess the ability of µPET/CT imaging to differentiate changes in rat bone tissue density and microstructure induced by metabolic bone diseases more accurately than current available methods...
  19. doi request reprint Specimen size and porosity can introduce error into microCT-based tissue mineral density measurements
    Roberto J Fajardo
    Orthopedic Biomechanics Laboratory, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA, USA
    Bone 44:176-84. 2009
    ..Measurements of rho(m) of specimens of unequal size or quantities of bone mineral must be interpreted with caution unless appropriate steps are taken to minimize these potential artifacts...
  20. doi request reprint Assessment of the bilateral asymmetry of human femurs based on physical, densitometric, and structural rigidity characteristics
    Melissa A Pierre
    Center for Advanced Orthopaedic Studies, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA
    J Biomech 43:2228-36. 2010
    ..In addition, our statistical analysis provides sample size estimates for planning future orthopedic research studies...
  21. doi request reprint Comparison of all-inside meniscal repair devices with matched inside-out suture repair
    Claudio Rosso
    Center for Advanced Orthopaedic Studies, Harvard Medical School, Boston, Massachusetts, USA
    Am J Sports Med 39:2634-9. 2011
    ..All-inside meniscal repairs are performed with increasing frequency because of the availability of newly developed devices. A comparison of their biomechanical characteristics may aid physicians in selecting a method of meniscal repair...
  22. doi request reprint Design and validation of a testing system to assess torsional cancellous bone failure in conjunction with time-lapsed micro-computed tomographic imaging
    Ara Nazarian
    Orthopedic Biomechanics Laboratory OBL, Beth Israel Deaconess Medical Center and Harvard Medical School, 330 Brookline Avenue, RN115, Boston, MA 02215, USA
    J Biomech 41:3496-501. 2008
    ..In conclusion, a novel torsion testing system for non-homogeneous, orthotropic materials using the incremental step-wise application of torsion and simultaneous time-lapsed microCT imaging was designed and validated...
  23. doi request reprint Effects of tissue preservation on murine bone mechanical properties
    Ara Nazarian
    Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA 02215, USA
    J Biomech 42:82-6. 2009
    ..Future studies should address the long-term effects of both formalin fixation and freezing on the mechanical properties of murine bone...
  24. doi request reprint Finite element analysis and computed tomography based structural rigidity analysis of rat tibia with simulated lytic defects
    John A Rennick
    Center for Advanced Orthopaedic Studies, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA Department of Mechanical Engineering, Northeastern University, Boston, MA, USA
    J Biomech 46:2701-9. 2013
    ..In addition there exist a good correlation between structural rigidity parameters and experimental failure loads. In contrast, there was no correlation between average bone density and failure load. ..
  25. ncbi request reprint Direct percutaneous gene delivery to enhance healing of segmental bone defects
    Oliver B Betz
    Center for Molecular Orthopaedics, 221 Longwood Avenue, BLI 152, Boston, MA 02115, USA
    J Bone Joint Surg Am 88:355-65. 2006
    ..Direct transfer of osteogenic genes offers an alternative, clinically expeditious, cost-effective approach. We evaluated its potential in a well-established, critical-size, rat femoral defect model...
  26. ncbi request reprint Water- and fat-suppressed proton projection MRI (WASPI) of rat femur bone
    Yaotang Wu
    Laboratory for the Study of Skeletal Disorders and Rehabilitation, Department of Orthopaedic Surgery, Children s Hospital, Boston, Massachusetts 02115, USA
    Magn Reson Med 57:554-67. 2007
    ..Proton solid-matrix images of rat femurs with 0.4-mm resolution and 12-mm field of view (FOV) were obtained. This method provides a noninvasive means of studying bone matrix in small animals...
  27. doi request reprint Hutchinson-Gilford progeria is a skeletal dysplasia
    Catherine M Gordon
    Division of Adolescent Medicine and Endocrinology, Children s Hospital Boston, Harvard Medical School, Boston, MA, USA
    J Bone Miner Res 26:1670-9. 2011
    ..Dietary intake was adequate, confirming that HGPS does not represent a model of malnutrition-induced bone loss. Taken together, these findings suggest that the phenotype of HGPS represents a unique skeletal dysplasia...
  28. doi request reprint Finite element analysis and CT-based structural rigidity analysis to assess failure load in bones with simulated lytic defects
    Lorenzo Anez-Bustillos
    Center for Advanced Orthopaedic Studies, Beth Israel Deaconess Medical Center, 330 Brookline Avenue, RN115, Boston, MA 02215, USA Electronic address
    Bone 58:160-7. 2014
    ..The results in this study showed slight differences between the methods, yet validation in prospective patient studies should confirm these preliminary findings. ..
  29. ncbi request reprint Design and implementation of a novel mechanical testing system for cellular solids
    Ara Nazarian
    Orthopedic Biomechanics Laboratory, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachusetts 02215, USA
    J Biomed Mater Res B Appl Biomater 73:400-11. 2005
    ..Therefore, this approach complements the conventional mechanical testing methods by providing visual insight into the failure propagation mechanisms of cellular solids...
  30. doi request reprint The safe zone for TransFix fixation in anterior cruciate ligament reconstruction using the anteromedial portal technique
    Timothy J McGlaston
    Center for Advanced Orthopaedic Studies, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachusetts, USA
    Arthroscopy 27:77-82. 2011
    ....