Affiliation: Harvard University
Nadol J, Hedley Whyte E, Amr S, O Apos Malley J, Kamakura T. Histopathology of the Inner Ear in Charcot-Marie-Tooth Syndrome Caused by a Missense Variant (p.Thr65Ala) in the MPZ Gene. Audiol Neurootol. 2018;23:326-334 pubmed publisher
..The pathophysiology of cranial nerve dysfunction in CMT is unknown. Findings in the current case suggested, at least in cranial nerves 7 and 8, that a myelinopathy may be causative. ..
Nadol J, O Malley J, Burgess B, Galler D. Cellular immunologic responses to cochlear implantation in the human. Hear Res. 2014;318:11-7 pubmed publisher
..Platinum was identified as one of the antigens likely responsible for this cellular response. This foreign body response may in certain cases result in migration or even extrusion of an implant device. ..
Nadol J, Eddington D. Histologic evaluation of the tissue seal and biologic response around cochlear implant electrodes in the human. Otol Neurotol. 2004;25:257-62 pubmed
..This putative mechanism has implications for possible strategies to prevent meningitis after cochlear implantation. ..
Nadol J. Revision mastoidectomy. Otolaryngol Clin North Am. 2006;39:723-40, vi-vii pubmed
..The focus of this article is the management of recurrent cholesteatoma or suppuration; that is, failure to achieve either of the first two priorities. ..
Nadol J, Eddington D, Burgess B. Foreign body or hypersensitivity granuloma of the inner ear after cochlear implantation: one possible cause of a soft failure?. Otol Neurotol. 2008;29:1076-84 pubmed publisher
..A foreign body or hypersensitivity reaction in the form of giant cells and lymphocytic cell infiltration is common after cochlear implantation and may be one possible cause of soft failure. ..
Jung D, Nadol J, Folkerth R, Merola J. Histopathology of the Inner Ear in a Case With Recent Onset of Cogan's Syndrome: Evidence for Vasculitis. Ann Otol Rhinol Laryngol. 2016;125:20-4 pubmed publisher
Quesnel A, Nakajima H, Rosowski J, Hansen M, Gantz B, Nadol J. Delayed loss of hearing after hearing preservation cochlear implantation: Human temporal bone pathology and implications for etiology. Hear Res. 2016;333:225-234 pubmed publisher
..Reduction of the inflammatory and immune response to cochlear implantation may lead to better long term hearing preservation post-implantation. ..
Kamakura T, Nadol J. Correlation between word recognition score and intracochlear new bone and fibrous tissue after cochlear implantation in the human. Hear Res. 2016;339:132-41 pubmed publisher
..New bone formation may be reduced by limiting insertional trauma and increasing the biocompatibility of the electrodes. ..
Nadol J, Merchant S. Histopathology and molecular genetics of hearing loss in the human. Int J Pediatr Otorhinolaryngol. 2001;61:1-15 pubmed