Research Topics
| JOSEPH NADOLSummaryAffiliation: Harvard University Country: USA Publications
Research Grants
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Detail Information
Publications
Results after revision stapedectomy with malleus grip prosthesisSarp Sarac
Department of Otolaryngology, Massachusetts Eye and Ear Infirmary, Boston, Massachusetts 02114, USA
Ann Otol Rhinol Laryngol 115:317-22. 2006..Our results are similar to those published in the literature for malleus attachment stapedectomy and conventional revision incus stapedectomy...
Histopathology and molecular genetics of hearing loss in the humanJ B Nadol
Department of Otology and Laryngology, Harvard Medical School, Massachusetts Eye and Ear Infirmary, 243 Charles Street, Boston, MA 02114 3096, USA
Int J Pediatr Otorhinolaryngol 61:1-15. 2001....
Foreign body or hypersensitivity granuloma of the inner ear after cochlear implantation: one possible cause of a soft failure?Joseph B Nadol
Department of Otology and Laryngology, Harvard Medical School, Massachusetts Eye and Ear Infirmary, Boston, Massachusetts 02114, USA
Otol Neurotol 29:1076-84. 2008..A tissue response in the form of foreign body or a hypersensitivity reaction to cochlear implantation is common and may be one possible cause of a soft failure of cochlear implantation...- Revision mastoidectomyJoseph B Nadol
Department of Otology and Laryngology, Harvard Medical School, Boston, MA, USA
Otolaryngol Clin North Am 39:723-40, vi-vii. 2006..The focus of this article is the management of recurrent cholesteatoma or suppuration; that is, failure to achieve either of the first two priorities... - Histopathology of the inner ear relevant to cochlear implantationJoseph B Nadol
Department of Otology and Laryngology, Harvard Medical School, Boston, Mass, USA
Adv Otorhinolaryngol 64:31-49. 2006..Rupture of the basilar membrane may occur. Over time, new bone forms at the cochleostomy and along the implant track. Further investigation is necessary to evaluate the causes of variability of behavioral measures of performance... - Temporal bone histopathology in a case of sensorineural hearing loss caused by superficial siderosis of the central nervous system and treated by cochlear implantationJoseph B Nadol
Otopathology Laboratory, Massachusetts Eye and Ear Infirmary, Boston, Massachusetts 02114, USA
Otol Neurotol 32:748-55. 2011..To evaluate the histopathology of the temporal bones of a patient with documented superficial siderosis of the central nervous system who underwent right cochlear implantation six years before death... - Histologic evaluation of the tissue seal and biologic response around cochlear implant electrodes in the humanJoseph B Nadol
Department of Otology and Laryngology, Harvard Medical School, Boston, Massachusetts, USA
Otol Neurotol 25:257-62. 2004.... - Obituary: William W. Montgomery, MDJoseph B Nadol
Massachusetts Eye and Ear Infirmary, 243 Charles Street, Boston, MA 02114, USA
Laryngoscope 113:2228-9. 2003 - Otopathology in Mohr-Tranebjaerg syndromeFayez Bahmad
Department of Otolaryngology, Massachusetts Eye and Ear Infirmary, Boston, Massachusetts 02114 3096, USA
Laryngoscope 117:1202-8. 2007..MTS is caused by mutations in the DDP/TIMM8A gene, which encodes for a 97 amino acid polypeptide; this polypeptide is a translocase of the inner mitochondrial membrane... - Cochleosaccular dysplasia associated with a connexin 26 mutation in keratitis-ichthyosis-deafness syndromeAndrew J Griffith
Section on Gene Structure and Function, National Institute on Deafness and Other Communication Disorders, National Institutes of Health, Bethesda, MD, USA
Laryngoscope 116:1404-8. 2006..CONCLUSIONS: GJB2 mutations can cause deafness in KID syndrome, and possibly in other GJB2 mutant phenotypes, by disrupting cochlear differentiation... - Quantitative evaluation of new bone and fibrous tissue in the cochlea following cochlear implantation in the humanMehmet A Somdas
Department of Otology and Laryngology, Harvard Medical School Massachusetts Eye and Ear Infirmary, Boston, Mass, USA
Audiol Neurootol 12:277-84. 2007..This should assist in correlating psychophysical and speech perception tests with intracochlear pathology, evaluating both electrode design and the techniques of preserving residual auditory function... - Anatomy of the round window and hook region of the cochlea with implications for cochlear implantation and other endocochlear surgical proceduresPeter M M C Li
Department of Otology and Laryngology, Harvard Medical School Massachusetts Eye and Ear Infirmary, Boston, Massachusetts 02114, USA
Otol Neurotol 28:641-8. 2007..The goal of this study was to create a three-dimensional model of the anatomy of the hook region to identify the optimal site for cochleostomy in cochlear implant surgery... - Histopathology of the peripheral vestibular system after cochlear implantation in the humanOphir Handzel
Department of Otology and Laryngology, Harvard Medical School, Massachusetts Eye and Ear Infirmary, Boston, MA 02114, USA
Otol Neurotol 27:57-64. 2006..Hydrops could be caused by obstruction of endolymphatic flow in the ductus reuniens or in the hook portion of the cochlea or by damage to the lateral cochlear wall caused by implantation... - Analysis of intracochlear new bone and fibrous tissue formation in human subjects with cochlear implantsPeter M M C Li
Department of Otology and Laryngology, Harvard Medical School Massachusetts Eye and Ear Infirmary, Boston, Massachusetts 02114 3096, USA
Ann Otol Rhinol Laryngol 116:731-8. 2007..In this study we aimed to evaluate new bone and new fibrous tissue formation in the inner ear following cochlear implantation... - Axodendritic and dendrodendritic synapses within outer spiral bundles in a humanFabio A Thiers
Department of Otology and Laryngology, Harvard Medical School and Department of Otolaryngology, Boston, MA 02114, USA
Hear Res 164:97-104. 2002..Similarly, numerous presumed dendrodendritic synapses may provide a morphological substrate for interaction between dendrites of type II's... - Histopathology of human cochlear implants: correlation of psychophysical and anatomical measuresAayesha M Khan
Cochlear Implant Research Laboratory, Massachusetts Eye and Ear Infirmary, 243 Charles Street, Boston, MA 02114, USA
Hear Res 205:83-93. 2005..These results lead us to hypothesize that 3D techniques will be required to asses the impact of peripheral anatomy on the benefit patients derive from cochlear implantation... - Is word recognition correlated with the number of surviving spiral ganglion cells and electrode insertion depth in human subjects with cochlear implants?Aayesha M Khan
Department of Otology and Laryngology, Harvard Medical School, Boston, Massachusetts 02114, USA
Laryngoscope 115:672-7. 2005..The depth of insertion of a multichannel cochlear implant has also been suggested as a clinical variable that may be correlated with word recognition. In the current study these correlations were evaluated in 15 human subjects... - Pathology and pathophysiology of idiopathic sudden sensorineural hearing lossSaumil N Merchant
Otopathology Laboratory, Department of Otolaryngology, Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, Massachusetts, USA
Otol Neurotol 26:151-60. 2005..The cause and pathogenesis of idiopathic sudden sensorineural hearing loss remain unknown. Proposed theories include vascular occlusion, membrane breaks, and viral cochleitis... - Pathophysiology of Meniere's syndrome: are symptoms caused by endolymphatic hydrops?Saumil N Merchant
Otopathology Laboratory, Department of Otolaryngology, Massachusetts Eye and Ear Infirmary, Boston, Massachusetts 02114 3096, USA
Otol Neurotol 26:74-81. 2005..If the central hypothesis were true, every case of Meniere's syndrome should have hydrops and every case of hydrops should show the typical symptoms... - Temporal bone histopathology in alport syndromeSaumil N Merchant
Department of Otolaryngology, Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, MA, USA
Laryngoscope 114:1609-18. 2004..To determine the histopathologic abnormalities within the cochlea in Alport syndrome... - Malleus fixation: clinical and histopathologic findingsJeffrey P Harris
Department of Otology and Laryngology, Harvard Medical School and the Massachusetts Eye and Ear Infirmary, Boston, USA
Ann Otol Rhinol Laryngol 111:246-54. 2002..Certain audiometric findings may lead one to suspect the diagnosis. The surgical approach used depends on the individual anatomy, and surgery is usually highly effective in improving hearing... - William W. Montgomery, MD, 1923-2003Mark A Varvares
Ann Otol Rhinol Laryngol 113:1-4. 2004 - Human temporal bone consortium for research resource enhancementSaumil N Merchant
Otol Neurotol 29:271-4. 2008 - The widely patent cochleovestibular communication of Edward Cock is a distinct inner ear malformation: implications for cochlear implantationAayesha M Khan
Department of Otology and Laryngology, Harvard Medical School, The Department of Otolaryngology, Massachusetts Eye and Ear Infirmary, Boston, MA 02114, USA
Ann Otol Rhinol Laryngol 115:595-606. 2006..A better understanding of the anatomy will allow more effective surgical planning and techniques and may have a significant impact in improving outcomes... - Reciprocal innervation of outer hair cells in a human infantFabio A Thiers
Department of Otology and Laryngology, Harvard Medical School, Boston, MA 02114, USA
J Assoc Res Otolaryngol 3:269-78. 2002.... - Histopathology of the inner ear in unoperated acoustic neuromaMohd Ridzo Mahmud
Department of Otolaryngology, National University of Malaysia, Kuala Lumpur, Malaysia
Ann Otol Rhinol Laryngol 112:979-86. 2003..It is hypothesized that the proteinaceous material seen histologically may represent the products of up-regulated genes in acoustic neuroma, some of which may interfere with normal cochlear function... - Cochlin immunostaining of inner ear pathologic deposits and proteomic analysis in DFNA9 deafness and vestibular dysfunctionNahid G Robertson
Department of Pathology, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02115, USA
Hum Mol Genet 15:1071-85. 2006.... - Carcinoid tumor of the middle ear: clinical features, recurrences, and metastasesMitchell J Ramsey
Division of Otolaryngology, Tripler Army Medical Center, Honolulu, HI, USA
Laryngoscope 115:1660-6. 2005..Surgical treatment is recommended and tailored to the extent of disease. Patients with carcinoid tumor of the middle ear require indefinite follow-up for possible recurrence or metastasis... - Morphometric changes in the cochlear nucleus in patients who had undergone cochlear implantation for bilateral profound deafnessTing Kuang Chao
Department of Otolaryngology, Far Eastern Memorial Hospital, Pan-Chiao, Taipei, Taiwan
Hear Res 174:196-205. 2002..05). However, electrical stimulation provided by the cochlear implantation did not alter these morphometric changes in adult cochlear implant patients... - Proton beam radiosurgery for vestibular schwannoma: tumor control and cranial nerve toxicityDamien C Weber
Department of Radiation Oncology, Massachusetts General Hospital, Boston, Massachusetts, USA
Neurosurgery 53:577-86; discussion 586-8. 2003..We sought to determine the tumor control rate and cranial nerve function outcomes in patients with vestibular schwannomas who were treated with proton beam stereotactic radiosurgery... - Effect of cochlear implantation on residual spiral ganglion cell count as determined by comparison with the contralateral nonimplanted inner ear in humansAayesha M Khan
Department of Otology and Laryngology, Harvard Medical School, Boston, Massachusetts, USA
Ann Otol Rhinol Laryngol 114:381-5. 2005..Possible interpretations of this finding are discussed...
Research Grants
- ELECTRON MICROSCOPY OF THE HUMAN INNER EARJOSEPH NADOL; Fiscal Year: 2005..abstract_text> ..
- RESEARCH TRAINING IN OTOLARYNGOLOGYJOSEPH NADOL; Fiscal Year: 2006..abstract_text> ..
- ELECTRON MICROSCOPY OF THE HUMAN INNER EARJOSEPH NADOL; Fiscal Year: 2007....
- ELECTRON MICROSCOPY OF THE HUMAN INNER EARJOSEPH NADOL; Fiscal Year: 1993....
- ELECTRON MICROSCOPY OF THE HUMAN INNER EARJOSEPH NADOL; Fiscal Year: 2000..The third component is an in depth examination of the co-pathology and hearing loss associated with the basilar membrane thickening in the human cochlea that they have observed with aging. ..
- ELECTRON MICROSCOPY OF THE HUMAN INNER EARJoseph B Nadol; Fiscal Year: 2010....