Jean B Nachega

Summary

Affiliation: Harvard University
Country: USA

Publications

  1. ncbi request reprint Adherence to nonnucleoside reverse transcriptase inhibitor-based HIV therapy and virologic outcomes
    Jean B Nachega
    Johns Hopkins Bloomberg School of Public Health and Johns Hopkins School of Medicine, Baltimore, Maryland 21205, USA
    Ann Intern Med 146:564-73. 2007
  2. doi request reprint Antiretroviral therapy adherence and retention in care in middle-income and low-income countries: current status of knowledge and research priorities
    Jean B Nachega
    Harvard School of Public Health, Boston, Massachusetts 02115, USA
    Curr Opin HIV AIDS 5:70-7. 2010
  3. doi request reprint Association of antiretroviral therapy adherence and health care costs
    Jean B Nachega
    Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA
    Ann Intern Med 152:18-25. 2010
  4. pmc Patient-nominated, community-based HIV treatment supporters: patient perspectives, feasibility, challenges, and factors for success in HIV-infected South African adults
    Monique M Duwell
    Department of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA
    AIDS Patient Care STDS 27:96-102. 2013
  5. pmc Antiretroviral therapy adherence, virologic and immunologic outcomes in adolescents compared with adults in southern Africa
    Jean B Nachega
    Department of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA
    J Acquir Immune Defic Syndr 51:65-71. 2009
  6. pmc Randomized controlled trial of trained patient-nominated treatment supporters providing partial directly observed antiretroviral therapy
    Jean B Nachega
    Department of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA
    AIDS 24:1273-80. 2010
  7. ncbi request reprint Adherence to highly active antiretroviral therapy assessed by pharmacy claims predicts survival in HIV-infected South African adults
    Jean B Nachega
    Department of International Health, Johns Hopkins University, Bloomberg School of Public Health, Baltimore, MD 21205, USA
    J Acquir Immune Defic Syndr 43:78-84. 2006
  8. ncbi request reprint Treatment supporter to improve adherence to antiretroviral therapy in HIV-infected South African adults. A qualitative study
    Jean B Nachega
    Department of International Health, Johns Hopkins University, Bloomberg School of Public Health, Baltimore, Maryland 21215, USA
    J Acquir Immune Defic Syndr 43:S127-33. 2006
  9. pmc Impact of immune reconstitution inflammatory syndrome on antiretroviral therapy adherence
    Jean B Nachega
    University of Cape Town, Department of Medicine, Division of Clinical Pharmacology, Cape Town, South Africa Johns Hopkins University, Bloomberg School of Public Health, Departments of International Health and Epidemiology, Baltimore, Maryland, USA Johns Hopkins University, Center for Tuberculosis Research, Baltimore, Maryland, USA
    Patient Prefer Adherence 6:887-91. 2012
  10. ncbi request reprint Antiretroviral therapy adherence and drug-drug interactions in the aging HIV population
    Jean B Nachega
    Department of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland 21205, USA
    AIDS 26:S39-53. 2012

Detail Information

Publications21

  1. ncbi request reprint Adherence to nonnucleoside reverse transcriptase inhibitor-based HIV therapy and virologic outcomes
    Jean B Nachega
    Johns Hopkins Bloomberg School of Public Health and Johns Hopkins School of Medicine, Baltimore, Maryland 21205, USA
    Ann Intern Med 146:564-73. 2007
    ..Adherence of 95% or more to unboosted protease regimens is required for optimal virologic suppression in HIV-1-infected patients. Whether the same is true for nonnucleoside reverse transcriptase inhibitor (NNRTI)-based therapy is unclear...
  2. doi request reprint Antiretroviral therapy adherence and retention in care in middle-income and low-income countries: current status of knowledge and research priorities
    Jean B Nachega
    Harvard School of Public Health, Boston, Massachusetts 02115, USA
    Curr Opin HIV AIDS 5:70-7. 2010
    ..This review presents recent developments in both treatment adherence and retention of patients in low-income and middle-income countries...
  3. doi request reprint Association of antiretroviral therapy adherence and health care costs
    Jean B Nachega
    Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA
    Ann Intern Med 152:18-25. 2010
    ..Antiretroviral therapy (ART) adherence predicts HIV disease progression and survival, but its effect on direct health care costs is unclear...
  4. pmc Patient-nominated, community-based HIV treatment supporters: patient perspectives, feasibility, challenges, and factors for success in HIV-infected South African adults
    Monique M Duwell
    Department of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA
    AIDS Patient Care STDS 27:96-102. 2013
    ....
  5. pmc Antiretroviral therapy adherence, virologic and immunologic outcomes in adolescents compared with adults in southern Africa
    Jean B Nachega
    Department of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA
    J Acquir Immune Defic Syndr 51:65-71. 2009
    ..To determine adherence to and effectiveness of antiretroviral therapy (ART) in adolescents vs. adults in southern Africa...
  6. pmc Randomized controlled trial of trained patient-nominated treatment supporters providing partial directly observed antiretroviral therapy
    Jean B Nachega
    Department of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA
    AIDS 24:1273-80. 2010
    ..Directly observed therapy (DOT) for antiretroviral therapy (ART) may improve adherence, but there are limited data on its clinical effectiveness...
  7. ncbi request reprint Adherence to highly active antiretroviral therapy assessed by pharmacy claims predicts survival in HIV-infected South African adults
    Jean B Nachega
    Department of International Health, Johns Hopkins University, Bloomberg School of Public Health, Baltimore, MD 21205, USA
    J Acquir Immune Defic Syndr 43:78-84. 2006
    ..42-7.72, for CD4+ T-cell count<or=50 cells/microL vs >200 cells/microL). Pharmacy-based records may be a simple and effective population-level tool for monitoring adherence as HAART programs in Africa are scaled up...
  8. ncbi request reprint Treatment supporter to improve adherence to antiretroviral therapy in HIV-infected South African adults. A qualitative study
    Jean B Nachega
    Department of International Health, Johns Hopkins University, Bloomberg School of Public Health, Baltimore, Maryland 21215, USA
    J Acquir Immune Defic Syndr 43:S127-33. 2006
    ..In addition, our results suggest that interventions tailored to treatment supporter characteristics and relationship factors may be effective in influencing patients' antiretroviral therapy adherence...
  9. pmc Impact of immune reconstitution inflammatory syndrome on antiretroviral therapy adherence
    Jean B Nachega
    University of Cape Town, Department of Medicine, Division of Clinical Pharmacology, Cape Town, South Africa Johns Hopkins University, Bloomberg School of Public Health, Departments of International Health and Epidemiology, Baltimore, Maryland, USA Johns Hopkins University, Center for Tuberculosis Research, Baltimore, Maryland, USA
    Patient Prefer Adherence 6:887-91. 2012
    ..We determined the impact of immune reconstitution inflammatory syndrome (IRIS) on antiretroviral therapy (ART) adherence in a cohort of 274 human immunodeficiency virus (HIV)-infected South African adults initiating ART...
  10. ncbi request reprint Antiretroviral therapy adherence and drug-drug interactions in the aging HIV population
    Jean B Nachega
    Department of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland 21205, USA
    AIDS 26:S39-53. 2012
    ..Well designed ART adherence interventions and DDI studies are needed in the elderly HIV population...
  11. ncbi request reprint HIV treatment adherence, drug resistance, virologic failure: evolving concepts
    Jean B Nachega
    Departments of International Health and Epidemiology, Johns Hopkins Bloomberg School of Public Health, 615 North Wolfe Street, Baltimore, MD 21205, USA
    Infect Disord Drug Targets 11:167-74. 2011
    ....
  12. doi request reprint Depression, alcohol use and adherence to antiretroviral therapy in sub-Saharan Africa: a systematic review
    Etheldreda Nakimuli-Mpungu
    Department of Mental Health, Johns Hopkins Bloomberg School of Public Health, 624N Broadway, Hampton House, Baltimore, MD, 21205, USA
    AIDS Behav 16:2101-18. 2012
    ..45 (95% CI 0.31-0.66, Tau(2) = 0.20, P value = 0.000). Interventions to improve mental health of HIV-positive individuals and to support adherence are desperately needed in sub-Saharan Africa...
  13. doi request reprint Adherence to antiretroviral therapy during and after pregnancy in low-income, middle-income, and high-income countries: a systematic review and meta-analysis
    Jean B Nachega
    Department of International Health, Global Disease Epidemiology and Control Program, Johns Hopkins University Bloomberg School of Public Health, 615N Wolfe Street, Suite W5031, Baltimore, MD21205, USA
    AIDS 26:2039-52. 2012
    ..To estimate antiretroviral therapy (ART) adherence rates during pregnancy and postpartum in high-income, middle-income, and low-income countries...
  14. ncbi request reprint Severe mental illness at ART initiation is associated with worse retention in care among HIV-infected Ugandan adults
    Jean B Nachega
    Department of Medicine and Centre for Infectious Diseases, Stellenbosch University, Cape Town, South Africa
    Trop Med Int Health 18:53-7. 2013
    ..We aimed to measure the association between SMI at antiretroviral therapy (ART) initiation and subsequent retention in care in HIV-infected Ugandan adults...
  15. doi request reprint HIV-related stigma, isolation, discrimination, and serostatus disclosure: a global survey of 2035 HIV-infected adults
    Jean B Nachega
    1Department of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA
    J Int Assoc Physicians AIDS Care (Chic) 11:172-8. 2012
    ..Little is known globally about the perspectives of people living with HIV/AIDS (PLWHA) on perceived HIV-related stigma and its consequences...
  16. ncbi request reprint Addressing the Achilles' Heel in the HIV Care Continuum for the Success of a Test-and-Treat Strategy to Achieve an AIDS-Free Generation
    Jean B Nachega
    Department of Epidemiology, Infectious Diseases Epidemiology Research Program, Pittsburgh University Graduate School of Public Health, Pennsylvania Departments of Epidemiology and International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland Department of Medicine and Centre for Infectious Diseases, Stellenbosch University, Faculty of Medicine and Health Sciences, Cape Town, South Africa
    Clin Infect Dis 59:S21-7. 2014
    ....
  17. pmc The global status of HIV drug resistance: clinical and public-health approaches for detection, treatment and prevention
    Steven Y Hong
    Division of Geographic Medicine and Infectious Diseases, Tufts Medical Center, Tufts University School of Medicine, 150 Harrison Avenue, Boston, MA 02111, USA
    Infect Disord Drug Targets 11:124-33. 2011
    ..These HIVDR surveys are designed to be implemented in conjunction with annual monitoring of program and site factors known to create situations favorable to the developments of HIV DR...
  18. ncbi request reprint Management of adult active tuberculosis disease in era of HIV pandemic, current practices and future perspectives
    Jean B Nachega
    Department of International Health, Global Disease Epidemiology and Control Program, Johns Hopkins Bloomberg School of Public Health, 615 North Wolfe Street, Baltimore, MD 21205, USA
    Infect Disord Drug Targets 11:134-43. 2011
    ....
  19. ncbi request reprint Impact of metabolic complications on antiretroviral treatment adherence: clinical and public health implications
    Jean B Nachega
    Department of International Health, Global Disease Epidemiology and Control Program, Johns Hopkins Bloomberg School of Public Health, 615 N Wolfe Street, Suite W5031, Baltimore, MD 21205, USA
    Curr HIV/AIDS Rep 6:121-9. 2009
    ..In this article, we review the effects of these metabolic complications on ART adherence and approaches to prevent or reverse them...
  20. pmc Twice-daily versus once-daily antiretroviral therapy and coformulation strategies in HIV-infected adults: benefits, risks, or burden?
    Jean B Nachega
    Department of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA
    Patient Prefer Adherence 5:645-51. 2011
    ..Comprehensive cost-benefit analysis of regimen simplification could help facilitate evidence-based decisions regarding antiretroviral regimen choices...
  21. ncbi request reprint HIV/AIDS and antiretroviral treatment knowledge, attitudes, beliefs, and practices in HIV-infected adults in Soweto, South Africa
    Jean B Nachega
    Department of International Health, Johns Hopkins University, Bloomberg School of Public Health, Baltimore, MD, USA
    J Acquir Immune Defic Syndr 38:196-201. 2005
    ..The low rate of HIV serostatus disclosure to sexual partners calls for multidimensional interventions to reduce HIV-related stigma...