Michael A Myre

Summary

Affiliation: Harvard University
Country: USA

Publications

  1. ncbi Clues to γ-secretase, huntingtin and Hirano body normal function using the model organism Dictyostelium discoideum
    Michael A Myre
    Molecular Neurogenetics Unit, Center for Human Genetic Research, Department of Neurology, Massachusetts General Hospital, Boston, MA 02114, USA
    J Biomed Sci 19:41. 2012
  2. ncbi Reduced amyloidogenic processing of the amyloid beta-protein precursor by the small-molecule Differentiation Inducing Factor-1
    Michael A Myre
    Molecular Neurogenetics Unit, Center for Human Genetic Research, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA
    Cell Signal 21:567-76. 2009
  3. ncbi Deficiency of huntingtin has pleiotropic effects in the social amoeba Dictyostelium discoideum
    Michael A Myre
    Molecular Neurogenetics Unit, Center for Human Genetic Research, Massachusetts General Hospital, Boston, Massachusetts, United States of America
    PLoS Genet 7:e1002052. 2011

Collaborators

Detail Information

Publications3

  1. ncbi Clues to γ-secretase, huntingtin and Hirano body normal function using the model organism Dictyostelium discoideum
    Michael A Myre
    Molecular Neurogenetics Unit, Center for Human Genetic Research, Department of Neurology, Massachusetts General Hospital, Boston, MA 02114, USA
    J Biomed Sci 19:41. 2012
    ....
  2. ncbi Reduced amyloidogenic processing of the amyloid beta-protein precursor by the small-molecule Differentiation Inducing Factor-1
    Michael A Myre
    Molecular Neurogenetics Unit, Center for Human Genetic Research, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA
    Cell Signal 21:567-76. 2009
    ..Our findings suggest that DIF-1 affects G0/G1-associated amyloidogenic processing of APP by a gamma-secretase-, proteasome- and calpain-insensitive pathway, and that this effect requires the presence of residue Thr668...
  3. ncbi Deficiency of huntingtin has pleiotropic effects in the social amoeba Dictyostelium discoideum
    Michael A Myre
    Molecular Neurogenetics Unit, Center for Human Genetic Research, Massachusetts General Hospital, Boston, Massachusetts, United States of America
    PLoS Genet 7:e1002052. 2011
    ..Thus, Dictyostelium provides a novel haploid organism model for genetic, cell biological, and biochemical studies to delineate the functions of the HD protein...