Megan B Murray

Summary

Affiliation: Harvard University
Country: USA

Publications

  1. pmc Determinants of cluster distribution in the molecular epidemiology of tuberculosis
    Megan Murray
    Department of Epidemiology, Harvard School of Public Health and Infectious Disease Unit, Massachusetts General Hospital, 677 Huntington Avenue, Boston, MA, 02115, USA
    Proc Natl Acad Sci U S A 99:1538-43. 2002
  2. doi request reprint Modeling social, environmental and biological determinants of tuberculosis
    M Murray
    Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts 02115, USA
    Int J Tuberc Lung Dis 15:S64-70. 2011
  3. pmc Tuberculosis and poverty: why are the poor at greater risk in India?
    Olivia Oxlade
    Department of Epidemiology, Harvard School of Public Health, Boston, MA, USA
    PLoS ONE 7:e47533. 2012
  4. pmc Barriers to successful tuberculosis treatment in Tomsk, Russian Federation: non-adherence, default and the acquisition of multidrug resistance
    I Y Gelmanova
    Partners In Health Russia, Moscow, Russian Federation
    Bull World Health Organ 85:703-11. 2007
  5. pmc Adaptation of a web-based, open source electronic medical record system platform to support a large study of tuberculosis epidemiology
    Hamish S F Fraser
    Division of Global Health Equity, Brigham and Women s Hospital, Boston, MA, USA
    BMC Med Inform Decis Mak 12:125. 2012
  6. pmc Comprehensive and integrated district health systems strengthening: the Rwanda Population Health Implementation and Training (PHIT) Partnership
    Peter C Drobac
    Partners In Health Inshuti Mu Buzima, Rwinkwavu, Rwanda
    BMC Health Serv Res 13:S5. 2013
  7. ncbi request reprint Measles outbreak in a northern Pakistani village: epidemiology and vaccine effectiveness
    M Murray
    Department of Epidemiology, Harvard School of Public Health, Boston, MA 02115, USA
    Am J Epidemiol 151:811-9. 2000
  8. pmc The effects of International Monetary Fund loans on health outcomes
    Megan Murray
    Harvard School of Public Health, Boston, Massachusetts, United States of America
    PLoS Med 5:e162. 2008
  9. pmc Molecular epidemiology and the dynamics of tuberculosis transmission among foreign-born people
    Megan B Murray
    Harvard School of Public Health, Boston, MA 02115, USA
    CMAJ 167:355-6. 2002
  10. pmc Sampling bias in the molecular epidemiology of tuberculosis
    Megan Murray
    Department of Epidemiology, Harvard School of Public Health, Boston, Massachussetts 02115, USA
    Emerg Infect Dis 8:363-9. 2002

Research Grants

Collaborators

Detail Information

Publications58

  1. pmc Determinants of cluster distribution in the molecular epidemiology of tuberculosis
    Megan Murray
    Department of Epidemiology, Harvard School of Public Health and Infectious Disease Unit, Massachusetts General Hospital, 677 Huntington Avenue, Boston, MA, 02115, USA
    Proc Natl Acad Sci U S A 99:1538-43. 2002
    ..We consider the implications of these results for the interpretation of cluster studies of M. tuberculosis as well as the more general application of microsimulation models to infectious disease epidemiology...
  2. doi request reprint Modeling social, environmental and biological determinants of tuberculosis
    M Murray
    Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts 02115, USA
    Int J Tuberc Lung Dis 15:S64-70. 2011
    ..We conclude by defining research priorities in both the study of specific determinants and the development of appropriate models to assess the impact of addressing these determinants...
  3. pmc Tuberculosis and poverty: why are the poor at greater risk in India?
    Olivia Oxlade
    Department of Epidemiology, Harvard School of Public Health, Boston, MA, USA
    PLoS ONE 7:e47533. 2012
    ..The objective of our study was to investigate the mechanisms by which poverty increases the risk of TB...
  4. pmc Barriers to successful tuberculosis treatment in Tomsk, Russian Federation: non-adherence, default and the acquisition of multidrug resistance
    I Y Gelmanova
    Partners In Health Russia, Moscow, Russian Federation
    Bull World Health Organ 85:703-11. 2007
    ....
  5. pmc Adaptation of a web-based, open source electronic medical record system platform to support a large study of tuberculosis epidemiology
    Hamish S F Fraser
    Division of Global Health Equity, Brigham and Women s Hospital, Boston, MA, USA
    BMC Med Inform Decis Mak 12:125. 2012
    ..We added new reports for study managers, and developed data extraction tools for research staff and statisticians. Further adaptation to handle direct entry of laboratory data occurred after the study was launched...
  6. pmc Comprehensive and integrated district health systems strengthening: the Rwanda Population Health Implementation and Training (PHIT) Partnership
    Peter C Drobac
    Partners In Health Inshuti Mu Buzima, Rwinkwavu, Rwanda
    BMC Health Serv Res 13:S5. 2013
    ....
  7. ncbi request reprint Measles outbreak in a northern Pakistani village: epidemiology and vaccine effectiveness
    M Murray
    Department of Epidemiology, Harvard School of Public Health, Boston, MA 02115, USA
    Am J Epidemiol 151:811-9. 2000
    ..These observations suggest that, in some areas of the developing world, the age groups targeted to receive measles vaccinations may need to be broadened to ensure adequate coverage to prevent recurrent outbreaks...
  8. pmc The effects of International Monetary Fund loans on health outcomes
    Megan Murray
    Harvard School of Public Health, Boston, Massachusetts, United States of America
    PLoS Med 5:e162. 2008
  9. pmc Molecular epidemiology and the dynamics of tuberculosis transmission among foreign-born people
    Megan B Murray
    Harvard School of Public Health, Boston, MA 02115, USA
    CMAJ 167:355-6. 2002
  10. pmc Sampling bias in the molecular epidemiology of tuberculosis
    Megan Murray
    Department of Epidemiology, Harvard School of Public Health, Boston, Massachussetts 02115, USA
    Emerg Infect Dis 8:363-9. 2002
    ..The bias consistently results in underestimating recent transmission and the impact of risk factors for recent transmission...
  11. ncbi request reprint Methodological problems in the molecular epidemiology of tuberculosis
    Megan Murray
    Department of Epidemiology, Harvard School of Public Health, Boston, MA 02115, USA
    Am J Epidemiol 155:565-71. 2002
    ..They demonstrate ways to conduct sensitivity analyses of estimated results and suggest strategies that may improve the usefulness of this approach to studying tuberculosis...
  12. pmc The impact of diabetes on tuberculosis treatment outcomes: a systematic review
    Meghan A Baker
    Department of Epidemiology, Harvard School of Public Health, Boston, MA, USA
    BMC Med 9:81. 2011
    ..We performed a systematic review and meta-analysis to quantitatively summarize evidence for the impact of diabetes on tuberculosis outcomes...
  13. pmc Implementation of genotype MTBDRplus reduces time to multidrug-resistant tuberculosis therapy initiation in South Africa
    Karen R Jacobson
    Division of Infectious Diseases, Massachusetts General Hospital, Boston, MA 02114, USA
    Clin Infect Dis 56:503-8. 2013
    ..We sought to determine whether implementation of the rapid MTBDRplus diagnostic shortened the time from specimen collection to patient MDR tuberculosis therapy initiation...
  14. pmc Treatment outcomes of isoniazid-resistant tuberculosis patients, Western Cape Province, South Africa
    Karen R Jacobson
    Division of Infectious Diseases, Massachusetts General Hospital, Boston, Massachusetts 02114, USA
    Clin Infect Dis 53:369-72. 2011
    ..These data reveal the need for early identification and aggressive follow-up of isoniazid monoresistance to increase treatment success...
  15. doi request reprint The risk of tuberculosis disease among persons with diabetes mellitus: a prospective cohort study
    Meghan A Baker
    Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts 02115, USA
    Clin Infect Dis 54:818-25. 2012
    ..In this study, we prospectively investigated the risk of tuberculosis among persons with diabetes stratified by severity...
  16. doi request reprint Recurrence after treatment for pulmonary multidrug-resistant tuberculosis
    Mercedes C Becerra
    Department of Global Health and Social Medicine, Harvard Medical School, Boston, MA 02115, USA
    Clin Infect Dis 51:709-11. 2010
    ..2% (95% confidence interval, 3.0%-8.2%) experienced true relapse. This is an upper-bound estimate of relapse on which new regimens must improve...
  17. pmc Epidemiologic inference from the distribution of tuberculosis cases in households in Lima, Peru
    Ellen Brooks-Pollock
    Department of Epidemiology, Harvard School of Public Health, Brigham and Women s Hospital, Massachusetts General Hospital, Boston, USA
    J Infect Dis 203:1582-9. 2011
    ..Tuberculosis (TB) often occurs among household contacts of people with active TB. It is unclear whether clustering of cases represents household transmission or shared household risk factors for TB...
  18. pmc Food insufficiency is a risk factor for suboptimal antiretroviral therapy adherence among HIV-infected adults in urban Peru
    Molly F Franke
    Department of Epidemiology, Harvard School of Public Health, Boston, MA, USA
    AIDS Behav 15:1483-9. 2011
    ..R. per 5 point increase:0.91; C.I.:[0.85, 0.98]) and good baseline adherence self-efficacy (O.R.:0.25; C.I.:[0.09, 0.69]). Interventions that ensure food security for HIV-infected individuals may help sustain high levels of adherence...
  19. pmc The prevalence and drug sensitivity of tuberculosis among patients dying in hospital in KwaZulu-Natal, South Africa: a postmortem study
    Ted Cohen
    Division of Global Health Equity, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts, United States of America
    PLoS Med 7:e1000296. 2010
    ..We conducted limited autopsies on young adults dying in a single public hospital in the province of KwaZulu-Natal between October 2008 and August 2009 in order to estimate the magnitude of deaths attributable to tuberculosis...
  20. ncbi request reprint The effect of drug resistance on the fitness of Mycobacterium tuberculosis
    Ted Cohen
    Department of Epidemiology, Harvard School of Public Health, Boston, MA 02115, USA
    Lancet Infect Dis 3:13-21. 2003
    ..On the basis of these diverse lines of evidence, we conclude that the fitness estimates of drug-resistant M tuberculosis are quite heterogeneous and that this variation may preclude our ability to predict future trends of this pathogen...
  21. pmc Mycobacterium tuberculosis mutation rate estimates from different lineages predict substantial differences in the emergence of drug-resistant tuberculosis
    Christopher B Ford
    Department of Immunology and Infectious Diseases, Harvard School of Public Health, Boston, MA, USA
    Nat Genet 45:784-90. 2013
    ..These data suggest that interventions to prevent the emergence of drug-resistant tuberculosis should target bacterial as well as treatment-related risk factors. ..
  22. doi request reprint Bi-directional screening for tuberculosis and diabetes: a systematic review
    Christie Y Jeon
    Department of Epidemiology, Harvard School of Public Health, 641 Huntington Avenue, Boston, MA 02115, USA
    Trop Med Int Health 15:1300-14. 2010
    ..To assess the yield of finding additional TB or diabetes mellitus (DM) cases through systematic screening and to determine the effectiveness of preventive TB therapy in people with DM...
  23. pmc Risk factors and mortality associated with default from multidrug-resistant tuberculosis treatment
    Molly F Franke
    Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts 02115, USA
    Clin Infect Dis 46:1844-51. 2008
    ....
  24. pmc Treatment outcomes among patients with extensively drug-resistant tuberculosis: systematic review and meta-analysis
    Karen R Jacobson
    Division of Infectious Disease, Massachusetts General Hospital, Boston, Massachusetts 02114, USA
    Clin Infect Dis 51:6-14. 2010
    ..We conducted a meta-analysis to assess XDR TB treatment outcomes and to identify therapeutic approaches associated with favorable responses...
  25. pmc Antiviral resistance and the control of pandemic influenza
    Marc Lipsitch
    Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts, United States of America
    PLoS Med 4:e15. 2007
    ..Nonetheless, antiviral resistance has received little attention when evaluating these plans...
  26. pmc Exogenous re-infection and the dynamics of tuberculosis epidemics: local effects in a network model of transmission
    Ted Cohen
    Division of Social Medicine and Health Inequalities, Brigham and Women s Hospital, One Brigham Circle, Boston, MA 02120, USA
    J R Soc Interface 4:523-31. 2007
    ..These results have important implications for the development of TB control strategies...
  27. pmc Adjustment for missing data in complex surveys using doubly robust estimation: application to commercial sexual contact among Indian men
    Kathleen E Wirth
    Department of Epidemiology, Harvard School of Public Health, Boston, MA 02115, USA
    Epidemiology 21:863-71. 2010
    ..If respondents skip questions about behaviors perceived as socially undesirable, such interviews may introduce bias. We sought to implement a doubly robust estimator to correct for dependent missing data in this context...
  28. pmc Mixed-strain Mycobacterium tuberculosis infections among patients dying in a hospital in KwaZulu-Natal, South Africa
    Ted Cohen
    Division of Global Health Equity, Brigham and Women s Hospital, Boston, MA 02115, USA
    J Clin Microbiol 49:385-8. 2011
    ..Of 56 culture-positive samples genotyped, we detected mixed strains in five (9%) and clonal heterogeneity in an additional four (7%)...
  29. doi request reprint Tuberculosis burden in households of patients with multidrug-resistant and extensively drug-resistant tuberculosis: a retrospective cohort study
    Mercedes C Becerra
    Department of Global Health and Social Medicine, Harvard Medical School, Boston, MA 02115, USA
    Lancet 377:147-52. 2011
    ..WHO recommends contact investigation in close contacts of patients with MDR and XDR tuberculosis. We aimed to assess the burden of tuberculosis disease in household contacts of such patients...
  30. pmc Cost-effectiveness of treating multidrug-resistant tuberculosis
    Stephen C Resch
    Department of Health Policy and Management, Harvard School of Public Health, Harvard University, Boston, Massachusetts, United States of America
    PLoS Med 3:e241. 2006
    ..We projected the health benefits and cost-effectiveness of using drug susceptibility testing and second-line drugs in a lower-middle-income setting with high levels of MDR TB...
  31. pmc Incident tuberculosis among recent US immigrants and exogenous reinfection
    Ted Cohen
    Division of Social Medicine and Health Inequalities, Brigham and Women s Hospital, Boston, Massachusetts, USA
    Emerg Infect Dis 11:725-8. 2005
    ..We offer additional data from tuberculosis cases among recent US immigrants which strengthen the claim that reinfection in areas of intense transmission is common...
  32. pmc Beneficial and perverse effects of isoniazid preventive therapy for latent tuberculosis infection in HIV-tuberculosis coinfected populations
    Ted Cohen
    Division of Social Medicine and Health Inequalities, Brigham and Women s Hospital, One Brigham Circle, 1620 Tremont Street, Boston, MA 02120, USA
    Proc Natl Acad Sci U S A 103:7042-7. 2006
    ....
  33. pmc Molecular epidemiology of tuberculosis: achievements and challenges to current knowledge
    Megan Murray
    Department of Epidemiology, Harvard School of Public Health, Boston, MA, USA
    Bull World Health Organ 80:477-82. 2002
    ..We summarize the recent achievements in TB epidemiology associated with the introduction of DNA fingerprinting techniques, and consider the implications of this technology for the design and analysis of epidemiological studies...
  34. pmc Are survey-based estimates of the burden of drug resistant TB too low? Insight from a simulation study
    Ted Cohen
    Division of Social Medicine and Health Inequalities, Brigham and Women s Hospital, Boston, Massachusetts, United States of America
    PLoS ONE 3:e2363. 2008
    ....
  35. ncbi request reprint Mathematical models of the epidemiology and control of drug-resistant TB
    Ted Cohen
    Division of Global Health Equity, Brigham and Women s Hospital, Boston, MA, USA and Department of Epidemiology, Harvard School of Public Health, 677 Huntington Avenue, Boston, MA 02115, USA
    Expert Rev Respir Med 3:67-79. 2009
    ..These models also highlight knowledge gaps for which new research will improve our ability to project trends of drug resistance and develop more effective policies for its control...
  36. pmc The impact of realistic age structure in simple models of tuberculosis transmission
    Ellen Brooks-Pollock
    Department of Epidemiology, Harvard School of Public Health, Brigham and Women s Hospital, Boston, Massachusetts, United States of America
    PLoS ONE 5:e8479. 2010
    ..While previous work has addressed the mathematical description of TB natural history, the impact of demography on the behaviour of TB models has not been assessed...
  37. pmc Challenges in estimating the total burden of drug-resistant tuberculosis
    Ted Cohen
    Division of Social Medicine and Health Inequalities, Brigham and Women s Hospital, Boston, Massachusetts 02115, USA
    Am J Respir Crit Care Med 177:1302-6. 2008
    ....
  38. pmc Modeling the effects of strain diversity and mechanisms of strain competition on the potential performance of new tuberculosis vaccines
    Ted Cohen
    Division of Global Health Equity, Brigham and Women s Hospital, Boston MA 02115, USA
    Proc Natl Acad Sci U S A 105:16302-7. 2008
    ..tuberculosis within communities...
  39. ncbi request reprint Association between tobacco smoking and active tuberculosis in Taiwan: prospective cohort study
    Hsien Ho Lin
    Department of Epidemiology, Harvard School of Public Health, Boston, MA 02115, USA
    Am J Respir Crit Care Med 180:475-80. 2009
    ....
  40. pmc Emergent heterogeneity in declining tuberculosis epidemics
    Caroline Colijn
    Department of Epidemiology, Harvard School of Public Health, Boston, MA, USA
    J Theor Biol 247:765-74. 2007
    ..We discuss the implications of this finding for tuberculosis control in low incidence settings...
  41. doi request reprint Modifiable factors associated with tuberculosis disease in children: a case-control study
    Molly F Franke
    From the Department of Global Health and Social Medicine, Harvard Medical School Department of Epidemiology, Harvard School of Public Health, Boston, MA Partners In Health, Boston, MA Socios En Salud Sucursal Peru, Lima, Peru Instituto Nacional de Salud del Niño, Lima, Peru Division of Global Health Equity, Brigham and Women s Hospital, Boston, MA and Dartmouth Center for Health Care Delivery Science, Dartmouth College, Hanover, NH
    Pediatr Infect Dis J 33:109-11. 2014
    ..Consumption of fruits/vegetables ≥5 days/week was associated with a lower rate. Isoniazid uptake was low among children with a known contact. ..
  42. doi request reprint Polymorphisms in the gene that encodes the iron transport protein ferroportin 1 influence susceptibility to tuberculosis
    Meghan A Baker
    Division of Infectious Diseases, Department of Medicine, Massachusetts General Hospital, Boston, MA, USA
    J Infect Dis 205:1043-7. 2012
    ..We studied the association between iron intake and polymorphisms in the iron transporter gene SLC40A1 and the risk of tuberculosis...
  43. pmc Effectiveness of early antiretroviral therapy initiation to improve survival among HIV-infected adults with tuberculosis: a retrospective cohort study
    Molly F Franke
    Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts, United States of America
    PLoS Med 8:e1001029. 2011
    ..We aimed to examine whether early cART initiation improved survival among HIV-infected adults who were diagnosed with TB in a clinical setting...
  44. pmc Modeling epidemics of multidrug-resistant M. tuberculosis of heterogeneous fitness
    Ted Cohen
    Department of Epidemiology, Harvard School of Public Health, 677 Huntington Avenue, Boston, Massachusetts 02115, USA
    Nat Med 10:1117-21. 2004
    ....
  45. pmc Tuberculosis and poverty: the contribution of patient costs in sub-Saharan Africa--a systematic review
    Devra M Barter
    Department of Global Health and Population, Harvard School of Public Health, 677 Huntington Avenue, Boston, MA 02115, USA
    BMC Public Health 12:980. 2012
    ..In order to comprehensively assess the existing evidence on the costs that TB patients incur, we undertook a systematic review of the literature...
  46. pmc How does sex trafficking increase the risk of HIV Infection? An observational study from Southern India
    Kathleen E Wirth
    Department of Epidemiology, Harvard School of Public Health, Boston, MA 02115, USA
    Am J Epidemiol 177:232-41. 2013
    ..13, 95% confidence interval: 2.41, 51.40). These findings indicate that forced prostitution coupled with sexual violence probably explains the association between sex trafficking and HIV...
  47. pmc Transmission dynamics and control of severe acute respiratory syndrome
    Marc Lipsitch
    Department of Epidemiology, Harvard School of Public Health, 677 Huntington Avenue, Boston, MA 02115, USA
    Science 300:1966-70. 2003
    ..Public-health efforts to reduce transmission are expected to have a substantial impact on reducing the size of the epidemic...
  48. pmc Interpreting expression data with metabolic flux models: predicting Mycobacterium tuberculosis mycolic acid production
    Caroline Colijn
    Broad Institute of MIT and Harvard, Cambridge, Massachusetts, United States of America
    PLoS Comput Biol 5:e1000489. 2009
    ..Our method also predicts a number of additional potential modulators of TB mycolic acid biosynthesis. E-Flux thus provides a promising new approach for algorithmically predicting metabolic state from gene expression data...
  49. pmc Effects of smoking and solid-fuel use on COPD, lung cancer, and tuberculosis in China: a time-based, multiple risk factor, modelling study
    Hsien Ho Lin
    Department of Epidemiology, Harvard School of Public Health, Boston, MA, USA
    Lancet 372:1473-83. 2008
    ..We aimed to predict the effects of risk-factor trends on COPD, lung cancer, and tuberculosis...
  50. pmc Expanding tuberculosis case detection by screening household contacts
    Mercedes C Becerra
    Department of Social Medicine, Harvard Medical School, Boston, MA, USA
    Public Health Rep 120:271-7. 2005
    ..Our objective was to assess the feasibility and yield of a simple active case finding strategy in a high incidence population in northern Lima, Peru...
  51. pmc Systematic review of allelic exchange experiments aimed at identifying mutations that confer drug resistance in Mycobacterium tuberculosis
    Hanna Nebenzahl-Guimaraes
    Department of Epidemiology, Harvard School of Public Health, Boston, MA 02115, USA
    J Antimicrob Chemother 69:331-42. 2014
    ..tuberculosis drug resistance are superior to associational studies in elucidating an individual mutation's contribution to the drug resistance phenotype...
  52. pmc Diabetes mellitus increases the risk of active tuberculosis: a systematic review of 13 observational studies
    Christie Y Jeon
    Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts, United States of America
    PLoS Med 5:e152. 2008
    ..We conducted a systematic review and a meta-analysis of observational studies assessing the association of DM and TB in order to summarize the existing evidence and to assess methodological quality of the studies...
  53. pmc Isoniazid resistance and the future of drug-resistant tuberculosis
    Ted Cohen
    Department of Epidemiology, Harvard School of Public Health, Boston, MA 02115, USA
    Microb Drug Resist 10:280-5. 2004
    ..Here we present ecological evidence to support the hypothesis that mutations at the 315 position of katG confer isoniazid resistance for Mycobacterium tuberculosis without diminishing virulence or transmissibility...
  54. ncbi request reprint Multiple equilibria: tuberculosis transmission require unrealistic assumptions
    Marc Lipsitch
    Department of Epidemiology, Harvard School of Public Health, 677 Huntington Avenue, Boston, MA 02115 6028, USA
    Theor Popul Biol 63:169-70. 2003
  55. pmc Role of ferroportin in macrophage-mediated immunity
    Erin E Johnson
    Department of Genetics and Complex Diseases, Harvard School of Public Health, Boston, MA 02115, USA
    Infect Immun 78:5099-106. 2010
    ..The proinflammatory cytokine gamma interferon reversed the inhibitory effect of ferroportin overexpression on NO production. These results suggest a novel role for ferroportin in attenuating macrophage-mediated immune responses...
  56. pmc Siderocalin inhibits the intracellular replication of Mycobacterium tuberculosis in macrophages
    Erin E Johnson
    Department of Genetics and Complex Diseases, Harvard School of Public Health, Boston, MA, USA
    FEMS Immunol Med Microbiol 58:138-45. 2010
    ..Our findings are consistent with an important role for siderocalin in protection against M.tb infection and suggest that exogenously administered siderocalin may have therapeutic applications in tuberculosis...
  57. pmc Tobacco smoke, indoor air pollution and tuberculosis: a systematic review and meta-analysis
    Hsien Ho Lin
    Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts, United States of America
    PLoS Med 4:e20. 2007
    ..We undertook a systematic review and meta-analysis to quantitatively assess the association between these exposures and the risk of infection, disease, and death from TB...
  58. pmc Modeling bacterial evolution with comparative-genome-based marker systems: application to Mycobacterium tuberculosis evolution and pathogenesis
    David Alland
    Department of Medicine, Center for Emerging Pathogens, New Jersey Medical School, Newark, New Jersey 07103, USA
    J Bacteriol 185:3392-9. 2003
    ..Finally, we present population-based evidence that KasA, an important component of mycolic acid biosynthesis, develops G312S polymorphisms under selective pressure...

Research Grants5

  1. MACROPHAGE IRON METABOLISM AND TUBERCULOSIS INFECTION
    Megan Murray; Fiscal Year: 2007
    ..The elucidation of the role of host iron status on the growth of M. tuberculosis may help identify those at high risk for disease progression and lead to therapeutic interventions aimed at reducing macrophage iron stores. ..
  2. Curriculum in emerging infectious disease transmission (RMI)
    Megan Murray; Fiscal Year: 2007
    ....