B U Mueller

Summary

Affiliation: Harvard University
Country: USA

Publications

  1. ncbi request reprint The infant with a vascular tumor
    B U Mueller
    Department of Medicine, Harvard Medical School, Children s Hospital, Boston, MA 02115, USA
    Semin Perinatol 23:332-40. 1999
  2. pmc Serum and cerebrospinal fluid pharmacokinetics of intravenous and oral lamivudine in human immunodeficiency virus-infected children
    B U Mueller
    Pediatric Branch and Biostatistics and Data Management Section, National Cancer Institute, Bethesda, Maryland, USA
    Antimicrob Agents Chemother 42:3187-92. 1998
  3. pmc Pharmacokinetics of the protease inhibitor KNI-272 in plasma and cerebrospinal fluid in nonhuman primates after intravenous dosing and in human immunodeficiency virus-infected children after intravenous and oral dosing
    B U Mueller
    Pediatric Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA
    Antimicrob Agents Chemother 42:1815-8. 1998
  4. ncbi request reprint Long-term protease inhibitor-containing therapy results in limited improvement in T cell function but not restoration of interleukin-12 production in pediatric patients with AIDS
    C Chougnet
    Experimental Immunology Branch, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, USA
    J Infect Dis 184:201-5. 2001
  5. ncbi request reprint Kinetics of HIV-1 RNA concentration changes in pediatric patients
    S L Zeichner
    HIV and AIDS Malignancies Branch, National Cancer Institute, NIH, Bethesda, MD 20892, USA
    Pathobiology 64:289-94. 1996
  6. ncbi request reprint Correlation between reduction in plasma HIV-1 RNA concentration 1 week after start of antiretroviral treatment and longer-term efficacy
    M A Polis
    Laboratory of Immunoregulation, National Institute of Allergy and Infectious Diseases, Building 10, Room 11C103, National Institutes of Health NIH, Bethesda, MD 20892, USA
    Lancet 358:1760-5. 2001
  7. ncbi request reprint Cytomegalovirus infection in children with human immunodeficiency virus infection
    B J Kitchen
    Pediatric Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA
    Pediatr Infect Dis J 16:358-63. 1997
  8. ncbi request reprint Cancer in human immunodeficiency virus-infected children: a case series from the Children's Cancer Group and the National Cancer Institute
    M O Granovsky
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, USA
    J Clin Oncol 16:1729-35. 1998
  9. ncbi request reprint Long-term virologic and immunologic responses in human immunodeficiency virus type 1-infected children treated with indinavir, zidovudine, and lamivudine
    S Jankelevich
    HIV and AIDS Malignancy Branch, Division of Clinical Sciences, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, USA
    J Infect Dis 183:1116-20. 2001
  10. ncbi request reprint HIV-associated malignancies in children
    B U Mueller
    Department of Pediatrics, Harvard Medical School, Children s Hospital, Boston, Massachusetts, USA
    AIDS Patient Care STDS 13:527-33. 1999

Collaborators

Detail Information

Publications13

  1. ncbi request reprint The infant with a vascular tumor
    B U Mueller
    Department of Medicine, Harvard Medical School, Children s Hospital, Boston, MA 02115, USA
    Semin Perinatol 23:332-40. 1999
    ..Vascular lesions should be biopsied if there is any suspicion of malignancy...
  2. pmc Serum and cerebrospinal fluid pharmacokinetics of intravenous and oral lamivudine in human immunodeficiency virus-infected children
    B U Mueller
    Pediatric Branch and Biostatistics and Data Management Section, National Cancer Institute, Bethesda, Maryland, USA
    Antimicrob Agents Chemother 42:3187-92. 1998
    ..A limited-sampling strategy was developed to estimate the area under the concentration-time curve for concentrations in serum at 2 and 6 h...
  3. pmc Pharmacokinetics of the protease inhibitor KNI-272 in plasma and cerebrospinal fluid in nonhuman primates after intravenous dosing and in human immunodeficiency virus-infected children after intravenous and oral dosing
    B U Mueller
    Pediatric Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA
    Antimicrob Agents Chemother 42:1815-8. 1998
    ..The pharmacokinetic profile of KNI-272 may limit the drug's efficacy in vivo. It appears that KNI-272 will play a limited role in the treatment of HIV-infected children...
  4. ncbi request reprint Long-term protease inhibitor-containing therapy results in limited improvement in T cell function but not restoration of interleukin-12 production in pediatric patients with AIDS
    C Chougnet
    Experimental Immunology Branch, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, USA
    J Infect Dis 184:201-5. 2001
    ..These findings suggest that long-term nonsuppressive antiretroviral therapy can induce limited improvement in immune function in pediatric AIDS patients and that the effect of suppressive treatments should be investigated...
  5. ncbi request reprint Kinetics of HIV-1 RNA concentration changes in pediatric patients
    S L Zeichner
    HIV and AIDS Malignancies Branch, National Cancer Institute, NIH, Bethesda, MD 20892, USA
    Pathobiology 64:289-94. 1996
    ..These findings may have implications for understanding HIV-1 pathogenesis and the development of therapeutic protocols...
  6. ncbi request reprint Correlation between reduction in plasma HIV-1 RNA concentration 1 week after start of antiretroviral treatment and longer-term efficacy
    M A Polis
    Laboratory of Immunoregulation, National Institute of Allergy and Infectious Diseases, Building 10, Room 11C103, National Institutes of Health NIH, Bethesda, MD 20892, USA
    Lancet 358:1760-5. 2001
    ..75 or 1.00 log, respectively. We investigated the possibility of assessing drug efficacy from measurements of plasma HIV-1 concentrations made during the first week on therapy...
  7. ncbi request reprint Cytomegalovirus infection in children with human immunodeficiency virus infection
    B J Kitchen
    Pediatric Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA
    Pediatr Infect Dis J 16:358-63. 1997
    ..To determine retrospectively the prevalence of positive cytomegalovirus (CMV) cultures in pediatric patients with human immunodeficiency virus infection...
  8. ncbi request reprint Cancer in human immunodeficiency virus-infected children: a case series from the Children's Cancer Group and the National Cancer Institute
    M O Granovsky
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, USA
    J Clin Oncol 16:1729-35. 1998
    ..To describe the spectrum of malignancies in human immunodeficiency virus (HIV)-infected children and the clinical outcome of patients with these tumors...
  9. ncbi request reprint Long-term virologic and immunologic responses in human immunodeficiency virus type 1-infected children treated with indinavir, zidovudine, and lamivudine
    S Jankelevich
    HIV and AIDS Malignancy Branch, Division of Clinical Sciences, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, USA
    J Infect Dis 183:1116-20. 2001
    ..CD4+ CD45RA+ (naive) T cells were the major contributor to CD4+ T cell expansion. Continued long-term immunologic benefit may be experienced by a subset of children, despite only transient virologic suppression...
  10. ncbi request reprint HIV-associated malignancies in children
    B U Mueller
    Department of Pediatrics, Harvard Medical School, Children s Hospital, Boston, Massachusetts, USA
    AIDS Patient Care STDS 13:527-33. 1999
    ..Such regimens may be complicated, however, by multiple HIV-associated organ dysfunctions, drug interactions, and infectious complications secondary to severe immunosuppression...
  11. ncbi request reprint Cancers in children infected with the human immunodeficiency virus
    B U Mueller
    Harvard Medical School, Hunnewell Children s Hospital, Boston, Massachusetts 02115, USA
    Oncologist 4:309-17. 1999
    ..This article provides an overview of epidemiology and clinical and pathological presentations, as well as preliminary data regarding treatment options in children with HIV-associated malignancies...
  12. ncbi request reprint Prevention of red cell dehydration: a possible new treatment for sickle cell disease
    B U Mueller
    Children s Hospital, Harvard Medical School, Boston, Massachusetts, USA
    Pediatr Pathol Mol Med 20:15-25. 2001
    ..In this brief review, we discuss the pathophysiologic background and explore some new treatment options to prevent vaso-occlusive crises or other problems in this patient population...
  13. ncbi request reprint Chemokine gene expression and clonal analysis of B cells in tissues involved by lymphoid interstitial pneumonitis from HIV-infected pediatric patients
    J Teruya-Feldstein
    Laboratory of Pathology, Hematopathology Section, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892, USA
    Mod Pathol 14:929-36. 2001
    ..In addition, LIP may represent an early stage of MALT lymphoma or an immunologic response to a chronic antigenic stimulus that may provide a milieu or microenvironment for the evolution of a monoclonal B-cell population...