Ramon M Molina

Summary

Affiliation: Harvard University
Country: USA

Publications

  1. pmc Belgrade rats display liver iron loading
    Khristy Thompson
    Department of Genetics and Complex Diseases, Harvard School of Public Health, Boston, MA, 02115, USA
    J Nutr 136:3010-4. 2006
  2. pmc Ingestion of Mn and Pb by rats during and after pregnancy alters iron metabolism and behavior in offspring
    Ramon M Molina
    Program in Molecular and Integrative Physiological Sciences, Department of Environmental Health, Harvard School of Public Health, 665 Huntington Avenue, Boston, MA 02115, United States
    Neurotoxicology 32:413-22. 2011
  3. ncbi request reprint In vivo comparison of cat alveolar and pulmonary intravascular macrophages: phagocytosis, particle clearance, and cytoplasmic motility
    Ramon M Molina
    Molecular and Integrative Physiological Sciences Program, Department of Environmental Health, Harvard School of Public Health, Boston, Massachusetts 02115, USA
    Exp Lung Res 33:53-70. 2007
  4. ncbi request reprint Iron absorption by Belgrade rat pups during lactation
    Khristy Thompson
    Department of Genetics and Complex Diseases, Harvard School of Public Health, 665 Huntington Avenue, Boston, MA 02115, USA
    Am J Physiol Gastrointest Liver Physiol 293:G640-4. 2007
  5. pmc Influence of DMT1 and iron status on inflammatory responses in the lung
    Jonghan Kim
    Department of Genetics and Complex Diseases, Harvard School of Public Health, Boston, Massachusetts, USA
    Am J Physiol Lung Cell Mol Physiol 300:L659-65. 2011
  6. pmc Manganese uptake and distribution in the brain after methyl bromide-induced lesions in the olfactory epithelia
    Khristy J Thompson
    Molecular and Integrative Physiological Sciences Program, Department of Environmental Health, Harvard School of Public Health, Boston, Massachusetts 02115, USA
    Toxicol Sci 120:163-72. 2011
  7. pmc Effects of iron status on transpulmonary transport and tissue distribution of Mn and Fe
    Joseph D Brain
    Department of Environmental Health, Harvard School of Public Health, 665 Huntington Ave, Boston, MA 02115, USA
    Am J Respir Cell Mol Biol 34:330-7. 2006
  8. pmc Olfactory uptake of manganese requires DMT1 and is enhanced by anemia
    Khristy Thompson
    Department of Genetics and Complex Diseases, Harvard School of Public Health, 665 Huntington Ave, Boston, MA 02115, USA
    FASEB J 21:223-30. 2007
  9. ncbi request reprint Manganese and iron transport across pulmonary epithelium
    Elizabeth A Heilig
    Deptartment of Genetics and Complex Diseases, Harvard School of Public Health, 665 Huntington Avenue, Boston, MA 02115, USA
    Am J Physiol Lung Cell Mol Physiol 290:L1247-59. 2006
  10. pmc Pulmonary responses to Stachybotrys chartarum and its toxins: mouse strain affects clearance and macrophage cytotoxicity
    Jamie H Rosenblum Lichtenstein
    Department of Environmental Health, Program in Molecular and Integrative Physiological Sciences, Harvard School of Public Health, Boston, Massachusetts 02115, USA
    Toxicol Sci 116:113-21. 2010

Collaborators

Detail Information

Publications14

  1. pmc Belgrade rats display liver iron loading
    Khristy Thompson
    Department of Genetics and Complex Diseases, Harvard School of Public Health, Boston, MA, 02115, USA
    J Nutr 136:3010-4. 2006
    ..These results indicate that, similar to human patients with DMT1 mutations, Belgrade rats also display hepatic iron loading. Our data suggest this condition arises from ineffective erythropoiesis...
  2. pmc Ingestion of Mn and Pb by rats during and after pregnancy alters iron metabolism and behavior in offspring
    Ramon M Molina
    Program in Molecular and Integrative Physiological Sciences, Department of Environmental Health, Harvard School of Public Health, 665 Huntington Avenue, Boston, MA 02115, United States
    Neurotoxicology 32:413-22. 2011
    ..The data suggest that perturbation in Fe metabolism may contribute to the pathophysiologic consequences of Mn and Pb exposure during early development...
  3. ncbi request reprint In vivo comparison of cat alveolar and pulmonary intravascular macrophages: phagocytosis, particle clearance, and cytoplasmic motility
    Ramon M Molina
    Molecular and Integrative Physiological Sciences Program, Department of Environmental Health, Harvard School of Public Health, Boston, Massachusetts 02115, USA
    Exp Lung Res 33:53-70. 2007
    ..Our data show that PAMs have a slower rate of in vivo phagocytosis, higher cell motility, and faster particle clearance than PIMs...
  4. ncbi request reprint Iron absorption by Belgrade rat pups during lactation
    Khristy Thompson
    Department of Genetics and Complex Diseases, Harvard School of Public Health, 665 Huntington Avenue, Boston, MA 02115, USA
    Am J Physiol Gastrointest Liver Physiol 293:G640-4. 2007
    ..Tissue (59)Fe levels were also lower in b/b rats postgavage. Combined, these data suggest that DMT1 function is not essential for iron assimilation from milk during early development in the rat...
  5. pmc Influence of DMT1 and iron status on inflammatory responses in the lung
    Jonghan Kim
    Department of Genetics and Complex Diseases, Harvard School of Public Health, Boston, Massachusetts, USA
    Am J Physiol Lung Cell Mol Physiol 300:L659-65. 2011
    ..Loss of DMT1 alters pulmonary responses necessary for lung homeostasis in the basal state and enhances LPS-induced inflammation and therefore would contribute to progression of lung injury...
  6. pmc Manganese uptake and distribution in the brain after methyl bromide-induced lesions in the olfactory epithelia
    Khristy J Thompson
    Molecular and Integrative Physiological Sciences Program, Department of Environmental Health, Harvard School of Public Health, Boston, Massachusetts 02115, USA
    Toxicol Sci 120:163-72. 2011
    ..We conclude that (1) sustentacular cells are necessary for Mn transport to the blood and (2) intact axonal projections are required for Mn transport from the nasal cavity to the olfactory bulb and brain...
  7. pmc Effects of iron status on transpulmonary transport and tissue distribution of Mn and Fe
    Joseph D Brain
    Department of Environmental Health, Harvard School of Public Health, 665 Huntington Ave, Boston, MA 02115, USA
    Am J Respir Cell Mol Biol 34:330-7. 2006
    ..Although lung DMT1 expression did not correlate with iron status, differences in pharmacokinetics of instilled metals suggest that their potential toxicity can be modified by iron status...
  8. pmc Olfactory uptake of manganese requires DMT1 and is enhanced by anemia
    Khristy Thompson
    Department of Genetics and Complex Diseases, Harvard School of Public Health, 665 Huntington Ave, Boston, MA 02115, USA
    FASEB J 21:223-30. 2007
    ..The apparent function of DMT1 in olfactory manganese absorption suggests that the neurotoxicity of the metal can be modified by iron status due to the iron-responsive regulation of the transporter...
  9. ncbi request reprint Manganese and iron transport across pulmonary epithelium
    Elizabeth A Heilig
    Deptartment of Genetics and Complex Diseases, Harvard School of Public Health, 665 Huntington Avenue, Boston, MA 02115, USA
    Am J Physiol Lung Cell Mol Physiol 290:L1247-59. 2006
    ..These results demonstrate that iron and manganese are absorbed by the pulmonary epithelium through different pathways and reveal the potential role for nonselective calcium channels in lung metal clearance...
  10. pmc Pulmonary responses to Stachybotrys chartarum and its toxins: mouse strain affects clearance and macrophage cytotoxicity
    Jamie H Rosenblum Lichtenstein
    Department of Environmental Health, Program in Molecular and Integrative Physiological Sciences, Harvard School of Public Health, Boston, Massachusetts 02115, USA
    Toxicol Sci 116:113-21. 2010
    ..chartarum pulmonary effects. Analogous genetic differences among humans may contribute to reported variable sensitivity to S. chartarum...
  11. pmc Diminished organelle motion in murine Kupffer cells during the erythrocytic stage of malaria
    Charles F Bellows
    Molecular and Integrative Physiological Sciences Program, Harvard School of Public Health, 665 Huntington Avenue, Boston, MA 02115, USA
    J R Soc Interface 8:711-9. 2011
    ..We conclude that ingestion and metabolism of parasitized erythrocytes by liver macrophages during malaria infection decreases their organelle motion with likely consequences of compromised host defences...
  12. pmc Noninfectious entry of HIV-1 into peripheral and brain macrophages mediated by the mannose receptor
    J Roberto Trujillo
    Molecular and Integrative Physiological Sciences, Department of Environmental Health, Harvard School of Public Health, Boston, MA 02115, USA
    Proc Natl Acad Sci U S A 104:5097-102. 2007
    ..Therefore, characterization of the HIV-1 noninfectious MR-mediated phagocytic pathway may foster advances in HIV-1 vaccine design and an improved understanding of HIV-1/AIDS pathogenesis and host defenses...
  13. pmc Strain differences influence murine pulmonary responses to Stachybotrys chartarum
    Jamie H Rosenblum Lichtenstein
    Harvard School of Public Health, Molecular and Integrative Physiological Sciences, Department of Environmental Health, 665 Huntington Ave, Building 2 Room 219, Boston, MA 02115, USA
    Am J Respir Cell Mol Biol 35:415-23. 2006
    ..chartarum. These responses differ from those reported for LPS and other fungi. Analogous underlying genetic differences may contribute to the wide range of sensitivity to Stachybotrys among humans...
  14. doi request reprint Development and characterization of a Versatile Engineered Nanomaterial Generation System (VENGES) suitable for toxicological studies
    Philip Demokritou
    Department of Environmental Health, Harvard School of Public Health, Harvard University, Boston, MA 02215, USA
    Inhal Toxicol 22:107-16. 2010
    ..We demonstrated linkage between physicochemical ENM properties and potential toxicity...