Genomes and Genes


Stephanie E Mohr


Affiliation: Harvard University
Country: USA


  1. Mohr S, Hu Y, Rudd K, BUCKNER M, Gilly Q, Foster B, et al. Reagent and Data Resources for Investigation of RNA Binding Protein Functions in Drosophila melanogaster Cultured Cells. G3 (Bethesda). 2015;5:1919-24 pubmed publisher
    ..Importantly, we make the baseline data, including more than 200,000 images, easily accessible online. ..
  2. Hu Y, Comjean A, Roesel C, Vinayagam A, Flockhart I, ZIRIN J, et al. database of the Drosophila RNAi screening center and transgenic RNAi project: 2017 update. Nucleic Acids Res. 2017;45:D672-D678 pubmed publisher
    ..g. CRISPR) and support of integrated, cross-species approaches to uncovering gene function using functional genomics and other approaches. ..
  3. Yilmazel B, Hu Y, Sigoillot F, Smith J, Shamu C, Perrimon N, et al. Online GESS: prediction of miRNA-like off-target effects in large-scale RNAi screen data by seed region analysis. BMC Bioinformatics. 2014;15:192 pubmed publisher
    ..With the tool, users can either use a built-in database or provide a database of transcripts for analysis. This makes it possible to analyze RNAi data from any organism for which the user can provide transcript sequences. ..
  4. Mohr S, Rudd K, Hu Y, Song W, Gilly Q, BUCKNER M, et al. Zinc Detoxification: A Functional Genomics and Transcriptomics Analysis in Drosophila melanogaster Cultured Cells. G3 (Bethesda). 2018;8:631-641 pubmed publisher
  5. Hu Y, Flockhart I, Vinayagam A, Bergwitz C, Berger B, Perrimon N, et al. An integrative approach to ortholog prediction for disease-focused and other functional studies. BMC Bioinformatics. 2011;12:357 pubmed publisher DIOPT and DIOPT-DIST are useful resources for researchers working with model organisms, especially those who are interested in exploiting model organisms such as Drosophila to study the functions of human disease genes. ..