Research Topics
| S L MitchellSummaryAffiliation: Harvard University Country: USA Publications
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Detail Information
Publications
Dying with advanced dementia in the nursing homeSusan L Mitchell
Research and Training Institute, Hebrew Rehabilitation Center for Aged, Boston, MA 02131, USA
Arch Intern Med 164:321-6. 2004..Nursing homes are important providers of end-of-life care to persons with advanced dementia...- A national study of the location of death for older persons with dementiaSusan L Mitchell
Hebrew Rehabilitation Center for Aged Research and Training Institute, Boston, Massachusetts 02131, USA
J Am Geriatr Soc 53:299-305. 2005..To describe where older Americans with dementia die and to compare the state health system factors related to the location of dementia-related deaths with those of cancer and all other conditions in this population... - Estimating prognosis for nursing home residents with advanced dementiaSusan L Mitchell
Hebrew Rehabilitation Center for Aged Research and Training Institute, The Harvard Medical School, Boston, Mass 02131, USA
JAMA 291:2734-40. 2004..Survival varies for patients with advanced dementia, and accurate prognostic tools have not been developed. A small proportion of patients admitted to hospice have dementia, in part because of the difficulty in predicting survival... - Tube-feeding versus hand-feeding nursing home residents with advanced dementia: a cost comparisonSusan L Mitchell
Hebrew Rehabilitation Center for Aged Research and Training Institute, Department of Medicine of Beth Israel Deaconess Medical Center, Division on Aging, Harvard Medical School, Boston, MA 02131, USA
J Am Med Dir Assoc 5:S22-9. 2004..To compare the costs associated with caring for severely demented residents nursing homes with and without feeding tubes... - Clinical and organizational factors associated with feeding tube use among nursing home residents with advanced cognitive impairmentSusan L Mitchell
Hebrew Rehabilitation Center for Aged Research and Training Institute, Department of Medicine, Beth Israel Deaconess Medical Center, and Division on Aging, Harvard Medical School, Boston, MA 02131, USA
JAMA 290:73-80. 2003..Empiric data and expert opinion suggest that use of feeding tubes is not beneficial for older persons with advanced dementia. Previous research has shown a 10-fold variation in this practice across the United States... - Tube-feeding versus hand-feeding nursing home residents with advanced dementia: a cost comparisonSusan L Mitchell
Hebrew Rehabilitation Center for Aged Research and Training Institute, the Department of Medicine of Beth Israel Deaconess Medical Center, and the Division on Aging, Harvard Medical School, Boston, MA 02131, USA
J Am Med Dir Assoc 4:27-33. 2003..To compare the costs associated with caring for severely demented residents nursing homes with and without feeding tubes... - Nursing home characteristics associated with tube feeding in advanced cognitive impairmentSusan L Mitchell
Hebrew Rehabilitation Center for Aged Research and Training Institute, Harvard Medical School, Boston, Massachusetts 02131, USA
J Am Geriatr Soc 51:75-9. 2003..To identify nursing homes factors associated with the use of tube feeding in advanced cognitive impairment... - Survival after percutaneous endoscopic gastrostomy placement in older personsS L Mitchell
Division of Geriatric Medicine, Loeb Health Research Institute, Ottawa Hospital, University of Ottawa, Ontario, Canada
J Gerontol A Biol Sci Med Sci 55:M735-9. 2000..This report critically synthesizes the evidence regarding the impact of percutaneous endoscopic gastrostomy (PEG) tube placement on survival in older persons... - The association between antiulcer medication and initiation of cobalamin replacement in older personsS L Mitchell
Division of Geriatric Medicine and the Clinical Epidemiology Unit, Loeb Health Research Institute, the Ottawa Hospital and the University of Ottawa, Ontario, Canada
J Clin Epidemiol 54:531-4. 2001..While the relationship is not unambiguously causal, this finding underscores the need for judicious prescribing of antiulcer medications for older persons... - The risk factors and impact on survival of feeding tube placement in nursing home residents with severe cognitive impairmentS L Mitchell
Hebrew Rehabilitation Center for Aged Research and Training Institute, Department of Medicine, Beth Israel Deaconess Medical Center, Boston, Mass USA
Arch Intern Med 157:327-32. 1997..The provision of artificial enteral nutrition to an aged person with severe cognitive impairment is a complex dilemma in the long-term care setting... - Satisfaction with end-of-life care for nursing home residents with advanced dementiaSharon E Engel
School of Medicine, Emory University, Atlanta, Georgia 30306, USA
J Am Geriatr Soc 54:1567-72. 2006..To identify factors associated with satisfaction with care for healthcare proxies (HCPs) of nursing home (NH) residents with advanced dementia... - The hierarchy of functional loss associated with cognitive decline in older personsV Njegovan
Geriatric Assessment Unit, Ottawa Hospital, Ottawa, Ontario, Canada
J Gerontol A Biol Sci Med Sci 56:M638-43. 2001.... - Does artificial enteral nutrition prolong the survival of institutionalized elders with chewing and swallowing problems?S L Mitchell
Hebrew Rehabilitation Center for Aged Research and Training Institute, Department of Medicine of Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA
J Gerontol A Biol Sci Med Sci 53:M207-13. 1998..The objective of this study was to determine the impact of feeding tubes on the survival of nursing home residents with chewing and swallowing problems, and to follow the course of the tube-fed residents over one year... - Associations between end-of-life discussions, patient mental health, medical care near death, and caregiver bereavement adjustmentAlexi A Wright
Department of Medical Oncology and Center for Psycho Oncology and Palliative Care Research, Dana Farber Cancer Institute, 550 Shields Warren, 44 Binney St, Boston, MA 02115, USA
JAMA 300:1665-73. 2008..Talking about death can be difficult. Without evidence that end-of-life discussions improve patient outcomes, physicians must balance their desire to honor patient autonomy against a concern of inflicting psychological harm... - Decisions to hospitalize nursing home residents dying with advanced dementiaJennifer L Lamberg
Hebrew SeniorLife, Research and Training Institute, Boston, Massachusetts 02131, USA
J Am Geriatr Soc 53:1396-401. 2005..Thus, hospital transfers are common near the end of life. The finding that DNH orders are associated with patient and surrogate factors can help clinicians identify cases in which decisions to forgo hospitalizations may be facilitated... - Do financial incentives of introducing case mix reimbursement increase feeding tube use in nursing home residents?Joan M Teno
Center for Gerontology and Health Care Research, Department of Community Health, The Warren Alpert Medical School, Brown University, Providence, Rhode Island, USA
J Am Geriatr Soc 56:887-90. 2008..To determine whether adoption of Medicaid case mix reimbursement is associated with greater prevalence of feeding tube use in nursing home (NH) residents... - A decision aid for long-term tube feeding in cognitively impaired older personsS L Mitchell
Division of Geriatrics, The Ottawa Hospital, University of Ottawa, Ontario, Canada
J Am Geriatr Soc 49:313-6. 2001..There are particular challenges for developing and evaluating these tools in the context of end-of-life decisions... - Defining parkinsonism in the Canadian Study of Health and AgingS L Mitchell
Division of Geriatric Medicine Loeb Health Research Institute, the Ottawa Hospital and the University of Ottawa, Ontario, Canada
Int Psychogeriatr 13:107-13. 2001..Despite limitations, the approach presented in this article is a valid method to operationalize parkinsonism from the dataset... - Multidrug-resistant gram-negative bacteria in a long-term care facility: prevalence and risk factorsAurora Pop-Vicas
Division of Infectious Diseases, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts02215, USA
J Am Geriatr Soc 56:1276-80. 2008..To quantify the prevalence, risk factors, and mode of transmission associated with colonization by multidrug-resistant gram-negative bacteria (MDRGN) in the long-term care (LTC) setting... - Occurrence and treatment of suspected pneumonia in long-term care residents dying with advanced dementiaJen Hau Chen
Hebrew SeniorLife, Research and Training Institute and Department of Medicine, Beth Israel Deaconess Medical Center, Boston, Massachusetts 02131, USA
J Am Geriatr Soc 54:290-5. 2006..To describe the occurrence and management of suspected pneumonia in end-stage dementia and to identify factors associated with aggressiveness of antibiotic treatment... - Family oversight and the quality of nursing home care for residents with advanced dementiaDavid C Grabowski
Department of Health Care Policy, Harvard Medical School, 180 Longwood Avenue, Boston, MA 02115, USA
Med Care 47:568-74. 2009..One relatively understudied factor in the provision of NH care is the role of private oversight and monitoring by family members and friends... - Concerns about end-of-life care and support for euthanasiaJane L Givens
Division of Gerontology, Beth Israel Deaconess Medical Center and Hebrew SeniorLife Institute for Aging Research, Boston, Massachusetts, USA
J Pain Symptom Manage 38:167-73. 2009..Future work can evaluate whether alleviating these concerns may reduce the perceived desire for euthanasia by patients near the end of life... - Health care proxy grief symptoms before the death of nursing home residents with advanced dementiaDan K Kiely
Hebrew Senior Life, Institute for Aging Research, Center for Psychosocial Oncology and Palliative Care Research, Dana Farber Cancer Institute, Boston, Massachusetts, USA
Am J Geriatr Psychiatry 16:664-73. 2008.... - Healthcare proxies of nursing home residents with advanced dementia: decisions they confront and their satisfaction with decision-makingJane L Givens
Division of Gerontology, Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA
J Am Geriatr Soc 57:1149-55. 2009..To describe the medical decisions confronting healthcare proxies (HCPs) of nursing home (NH) residents with advanced dementia and to identify factors associated with greater decision-making satisfaction... - The clinical course of advanced dementiaSusan L Mitchell
Hebrew SeniorLife Institute for Aging Research, Boston, MA 02131, USA
N Engl J Med 361:1529-38. 2009..Dementia is a leading cause of death in the United States but is underrecognized as a terminal illness. The clinical course of nursing home residents with advanced dementia has not been well described... - Use of video to facilitate end-of-life discussions with patients with cancer: a randomized controlled trialAreej El-Jawahri
Departments of Medicine, Neurology and Cancer Center, and Oncology, Massachusetts General Hospital, 50 Staniford St, 9th Floor, Boston, MA 02114, USA
J Clin Oncol 28:305-10. 2010..To determine whether the use of a goals-of-care video to supplement a verbal description can improve end-of-life decision making for patients with cancer... - The influence of nursing home culture on the use of feeding tubesRuth Palan Lopez
MGH Institute of Health Professions School of Nursing, Boston, MA 02129 4557, USA
Arch Intern Med 170:83-8. 2010..Studies suggest that organizational features of NHs are associated with this practice, but underlying reasons for these associations are poorly understood... - Daily medication use in nursing home residents with advanced dementiaJennifer Tjia
Division of Geriatric Medicine, University of Massachusetts Medical School, Worcester, Massachusetts 01605, USA
J Am Geriatr Soc 58:880-8. 2010..To describe the pattern and factors associated with daily medication use in nursing home (NH) residents with advanced dementia... - The advanced dementia prognostic tool: a risk score to estimate survival in nursing home residents with advanced dementiaSusan L Mitchell
Hebrew SeniorLife Institute for Aging Research, Beth Israel Deaconess Medical Center, Boston, Massachusetts 02131, USA
J Pain Symptom Manage 40:639-51. 2010..Estimating life expectancy is challenging in advanced dementia... - Survival and comfort after treatment of pneumonia in advanced dementiaJane L Givens
Division of Gerontology, Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA
Arch Intern Med 170:1102-7. 2010..The objective of this study was to examine the effect of antimicrobial treatment for suspected pneumonia on survival and comfort in patients with advanced dementia... - Antipsychotic and benzodiazepine use among nursing home residents: findings from the 2004 National Nursing Home SurveyDavid G Stevenson
Department of Health Care Policy, Harvard Medical School, Boston, MA, USA
Am J Geriatr Psychiatry 18:1078-92. 2010..To document the extent and appropriateness of use of antipsychotics and benzodiazepines among nursing home residents using a nationally representative survey... - Prediction of 6-month survival of nursing home residents with advanced dementia using ADEPT vs hospice eligibility guidelinesSusan L Mitchell
The Hebrew Senior Life, Institute for Aging Research, Boston, Massachusetts, USA
JAMA 304:1929-35. 2010..Estimating life expectancy is challenging in advanced dementia, potentially limiting the use of hospice care in these patients... - Patterns of antimicrobial use among nursing home residents with advanced dementiaErika D'Agata
Division of Infectious Diseases, Department of Medicine, Beth Israel Deaconess Medical Center, Boston, MA 02215, USA
Arch Intern Med 168:357-62. 2008..Nursing home residents with advanced dementia are at high risk of infections and antimicrobial exposure near the end of life. Detailed studies quantifying antimicrobial prescribing practices among these residents have not been performed... - Depressive symptom trajectories and associated risks among bereaved Alzheimer disease caregiversBaohui Zhang
Center for Psycho Oncology and Palliative Care Research, Dana Farber Cancer Institute, Boston, MA 02115, USA
Am J Geriatr Psychiatry 16:145-55. 2008..The present study sought to determine if subgroups of bereaved AD caregivers follow distinctive depressive symptom trajectories and the characteristics associated with membership in depressive symptom subgroups... - Advanced dementia research in the nursing home: the CASCADE studySusan L Mitchell
Hebrew Senior Life Institute for Aging Research, Department of Medicine of Beth Israel Deaconess Medical Center, Boston, MA, USA
Alzheimer Dis Assoc Disord 20:166-75. 2006..The CASCADE experience establishes the feasibility of conducting rigorous, multisite dementia NH research, and the described methodology serves as a detailed reference for subsequent CASCADE publications as results from the study emerge... - The influence of outpatient comprehensive geriatric assessment on survival: a meta-analysisHsu Ko Kuo
Hebrew Rehabilitation Center for Aged, Research and Training Institute, 1200 Centre Street, Boston, MA 02131, USA
Arch Gerontol Geriatr 39:245-54. 2004..Future researches of outpatient CGA should focus on coordinated and standardized measurement of outcomes related to functional status, institutionalization rate, and quality of life... - A 93-year-old man with advanced dementia and eating problemsSusan L Mitchell
Harvard Medical School and Department of Medicine, Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA
JAMA 298:2527-36. 2007.... - Terminal care for persons with advanced dementia in the nursing home and home care settingsSusan L Mitchell
Hebrew Rehabilitation Center for Aged Research and Training Institute, Boston, Massachusetts, USA
J Palliat Med 7:808-16. 2004..Many older persons with advanced dementia receive terminal care in nursing homes, others remain in the community with home care services... - The validity and reliability of scales for the evaluation of end-of-life care in advanced dementiaDan K Kiely
Hebrew SeniorLife Institute for Aging Research, Boston, MA, USA
Alzheimer Dis Assoc Disord 20:176-81. 2006..81). The results of this study demonstrate that the 3 EOLD scales demonstrate "internal consistency" reliability and demonstrate convergent validity, and further establish their utility in palliative care dementia research... - Hospice care for patients with dementiaSusan L Mitchell
Institute for Aging Research, Hebrew SeniorLife, Boston, Massachusetts 02131, USA
J Pain Symptom Manage 34:7-16. 2007..These data suggest that the evaluation of hospice care for older patients is generally high, and does not vary with respect to terminal diagnoses... - Decisions to forgo hospitalization in advanced dementia: a nationwide studySusan L Mitchell
Hebrew SeniorLife, Institute for Aging Research and Beth Israel Deaconess Medical Center, Boston, Massachusetts 02131, USA
J Am Geriatr Soc 55:432-8. 2007..To examine the prevalence and factors associated with decisions to forgo hospitalization in nursing home (NH) residents with advanced dementia... - Hospice care for patients with dementia: does volume make a difference?Susan C Miller
Center for Gerontology and Health Care Research, Department of Community Health, The Warren Alpert Medical School of Brown University, Providence, RI 02912, USA
J Pain Symptom Manage 35:283-91. 2008..Further study is needed to understand the nonintuitive negative association between higher volume and lower satisfaction. This study emphasizes the need for examination of quality outcomes by profit status... - Financial incentives for placing feeding tubes in nursing home residents with advanced dementiaSusan L Mitchell
J Am Geriatr Soc 51:129-31. 2003 - Prediction of 6-month mortality in nursing home residents with advanced dementia: validity of a risk scoreJenny T van der Steen
Department of Nursing Home Medicine, EMGO Institute of the VU University Medical Center, Amsterdam, The Netherlands
J Am Med Dir Assoc 8:464-8. 2007..We aim to validate a risk score that uses Minimum Data Set (MDS) to estimate 6-month mortality for nursing home residents with advanced dementia... - Racial and state differences in the designation of advance directives in nursing home residentsD K Kiely
Hebrew Rehabilitation Center for Aged Research and Training Institute, Boston, Massachusetts 02131, USA
J Am Geriatr Soc 49:1346-52. 2001..The distinctly higher rates of LWs among all racial groups in Ohio than in other states suggest that states can potentially increase the use of advance directives through intervention... - Terminal trajectories of functional decline in the long-term care settingJen Hau Chen
Hebrew SeniorLife, Institute for Aging Research, Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA
J Gerontol A Biol Sci Med Sci 62:531-6. 2007..Little is known about the terminal trajectories of functional decline among long-term care (LTC) residents dying with different diseases... - Using video images to improve the accuracy of surrogate decision-making: a randomized controlled trialAngelo E Volandes
General Medicine Unit, Department of Medicine, Massachusetts General Hospital, Boston, MA 02114, USA
J Am Med Dir Assoc 10:575-80. 2009..Unfortunately, multiple studies have shown that surrogates' knowledge of patient preferences is poor. We hypothesized that a video decision tool would improve concordance between patients and their surrogates for end-of-life preferences... - Video decision support tool for advance care planning in dementia: randomised controlled trialAngelo E Volandes
General Medicine Unit, Department of Medicine, Massachusetts General Hospital, 50 Staniford Street, Boston, MA 02114, USA
BMJ 338:b2159. 2009..To evaluate the effect of a video decision support tool on the preferences for future medical care in older people if they develop advanced dementia, and the stability of those preferences after six weeks... - Bereaved family members' evaluation of hospice care: what factors influence overall satisfaction with services?Ramona L Rhodes
The Warren Alpert Medical School of Brown University, Brown University, Providence, RI 02912, USA
J Pain Symptom Manage 35:365-71. 2008..02, CI=1.92-2.13). These four key processes of care appear to significantly influence an "excellent" rating of overall satisfaction with hospice care... - Nurses' perspectives on feeding decisions for nursing home residents with advanced dementiaRuth Palan Lopez
MGH Institute of Health Professions School of Nursing, Boston, MA 02129 4557, USA
J Clin Nurs 19:632-8. 2010..To develop a broad understanding of nursing beliefs, knowledge and roles in feeding decisions for nursing home residents with advanced dementia... - Physicians' intentions and use of three patient decision aidsIan D Graham
Ottawa Health Research Institute, Clinical Epidemiology Program, Ottawa, ON, Canada
BMC Med Inform Decis Mak 7:20. 2007..The purpose of this study was to describe physicians' perceptions of three decision aids, their expressed intent to use them, and their subsequent use of them... - Cholecystoenterostomy for treatment of extrahepatic biliary tract obstruction in cats: 22 cases (1994-2003)Nicole J Buote
Department of Clinical Sciences, Cummings School of Veterinary Medicine at Tufts University, North Grafton, MA 01536, USA
J Am Vet Med Assoc 228:1376-82. 2006..However, the overall prognosis for cats with EHBTO undergoing cholecystoenterostomy must be considered guarded to poor, and the incidence of perioperative complications is high... - Liver lobe torsion in dogs: 13 cases (1995-2004)Susanna G Hinkle Schwartz
Department of Clinical Sciences, Cummings School of Veterinary Medicine at Tufts University, North Grafton, MA 01536, USA
J Am Vet Med Assoc 228:242-7. 2006..Abdominal ultrasonography with Doppler assessment may be useful in establishing the diagnosis. The long-term outcome for dogs that survive the hospitalization period is excellent... - Oral cobalamin remains medicine's best kept secretIan D Graham
Clinical Epidemiology Program, Ottawa Health Research Institute, Room 2 008, Administrative Services Building, 1053 Carling Ave, Ottawa, Ont, Canada K1Y 4E9
Arch Gerontol Geriatr 44:49-59. 2007..Strategies to promote the use of oral cobalamin should be directed at educating physicians of its efficacy and providing them with prescribing information on where it can be purchased... - Extensive small bowel resection in dogs and cats: 20 cases (1998-2004)Stephanie C Gorman
Department of Clinical Sciences, Cummings School of Veterinary Medicine at Tufts University, North Grafton, MA 01536, USA
J Am Vet Med Assoc 228:403-7. 2006..The amount of intestine resected was not associated with outcome. These data may be useful in providing prognostic information in cases of extensive small intestinal resection...
Research Grants
- The ADEPT Study: Estimating Prognosis in Advanced DementiaSusan Mitchell; Fiscal Year: 2009..Thus, the information derived from this study has the potential to make important clinical, research and policy-relevant contributions to the care of older persons with dementia at the end-of-life. ..
- Tube-feeding in Elderly: Decision-making and OutcomesSusan Mitchell; Fiscal Year: 2003..By the end of the award period the applicant will have the skills, experience and research track record necessary to become an independent investigator and leader in academic geriatrics. ..
- The ADEPT Study: Estimating Prognosis in Advanced DementiaSusan Mitchell; Fiscal Year: 2007..Thus, the information derived from this study has the potential to make important clinical, research and policy-relevant contributions to the care of older persons with dementia at the end-of-life. ..
- The CASCADE Study: End-of-Life in Advanced DementiaSusan Mitchell; Fiscal Year: 2007..abstract_text> ..
- Determinants, Decision-Making and Outcomes of Antibiotic Use in Advanced DementiaSusan Mitchell; Fiscal Year: 2009....