G F Mitchell

Summary

Affiliation: Harvard University
Country: USA

Publications

  1. ncbi request reprint Equipotent antihypertensive agents variously affect pulsatile hemodynamics and regression of cardiac hypertrophy in spontaneously hypertensive rats
    G F Mitchell
    Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, Mass 02115, USA
    Circulation 94:2923-9. 1996
  2. ncbi request reprint Sphygmomanometrically determined pulse pressure is a powerful independent predictor of recurrent events after myocardial infarction in patients with impaired left ventricular function. SAVE investigators. Survival and Ventricular Enlargement
    G F Mitchell
    Cardiovascular Division, Brigham and Women s Hospital, Harvard Medical School, Boston, Mass 02115, USA
    Circulation 96:4254-60. 1997
  3. ncbi request reprint The heart and conduit vessels in hypertension
    G F Mitchell
    Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts, USA
    Med Clin North Am 81:1247-71. 1997
  4. ncbi request reprint Effects of reperfusion on arrhythmias and death after coronary artery occlusion in the rat: increased electrical stability independent of myocardial salvage
    C F Opitz
    Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA
    J Am Coll Cardiol 32:261-7. 1998
  5. ncbi request reprint Increased pulse pressure and risk of heart failure in the elderly
    C U Chae
    Department of Medicine, Brigham and Women s Hospital, Boston, MA 02215 1204, USA
    JAMA 281:634-9. 1999
  6. pmc Long QT and ventricular arrhythmias in transgenic mice expressing the N terminus and first transmembrane segment of a voltage-gated potassium channel
    B London
    Division of Cardiology, University of Pittsburgh Medical Center, Pittsburgh, PA 15213, USA
    Proc Natl Acad Sci U S A 95:2926-31. 1998
  7. ncbi request reprint Inducible polymorphic ventricular tachyarrhythmias in a transgenic mouse model with a long Q-T phenotype
    A Jeron
    Cardiovascular Division, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02115, USA
    Am J Physiol Heart Circ Physiol 278:H1891-8. 2000
  8. ncbi request reprint Characterization of mice with a combined suppression of I(to) and I(K,slow)
    M Brunner
    Cardiovascular Research Division, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA
    Am J Physiol Heart Circ Physiol 281:H1201-9. 2001

Collaborators

Detail Information

Publications8

  1. ncbi request reprint Equipotent antihypertensive agents variously affect pulsatile hemodynamics and regression of cardiac hypertrophy in spontaneously hypertensive rats
    G F Mitchell
    Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, Mass 02115, USA
    Circulation 94:2923-9. 1996
    ..However, the pulsatile component of hemodynamic load has not been evaluated in this model...
  2. ncbi request reprint Sphygmomanometrically determined pulse pressure is a powerful independent predictor of recurrent events after myocardial infarction in patients with impaired left ventricular function. SAVE investigators. Survival and Ventricular Enlargement
    G F Mitchell
    Cardiovascular Division, Brigham and Women s Hospital, Harvard Medical School, Boston, Mass 02115, USA
    Circulation 96:4254-60. 1997
    ..There is increasing evidence of a link between conduit vessel stiffness and cardiovascular events, although the association has never been tested in a large post-myocardial infarction patient population...
  3. ncbi request reprint The heart and conduit vessels in hypertension
    G F Mitchell
    Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts, USA
    Med Clin North Am 81:1247-71. 1997
    ..This article reviews the adaptation of the heart and vessels to hypertension, the clinical implications of these structural and functional changes, and the effects of therapy on cardiovascular function...
  4. ncbi request reprint Effects of reperfusion on arrhythmias and death after coronary artery occlusion in the rat: increased electrical stability independent of myocardial salvage
    C F Opitz
    Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA
    J Am Coll Cardiol 32:261-7. 1998
    ..This study sought to delineate salvage-dependent from salvage-independent coronary reperfusion in acute myocardial infarction and the effects on spontaneously occurring arrhythmias and arrhythmic death in rats...
  5. ncbi request reprint Increased pulse pressure and risk of heart failure in the elderly
    C U Chae
    Department of Medicine, Brigham and Women s Hospital, Boston, MA 02215 1204, USA
    JAMA 281:634-9. 1999
    ..Arterial stiffness increases with age. Thus, pulse pressure, an index of arterial stiffening, may predict congestive heart failure (CHF) in the elderly...
  6. pmc Long QT and ventricular arrhythmias in transgenic mice expressing the N terminus and first transmembrane segment of a voltage-gated potassium channel
    B London
    Division of Cardiology, University of Pittsburgh Medical Center, Pittsburgh, PA 15213, USA
    Proc Natl Acad Sci U S A 95:2926-31. 1998
    ..These changes correlate with a marked decrease in the level of Kv1.5 polypeptide. Thus, overexpression of a truncated K+ channel in the heart alters native K+ channel expression and has profound effects on cardiac excitability...
  7. ncbi request reprint Inducible polymorphic ventricular tachyarrhythmias in a transgenic mouse model with a long Q-T phenotype
    A Jeron
    Cardiovascular Division, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02115, USA
    Am J Physiol Heart Circ Physiol 278:H1891-8. 2000
    ....
  8. ncbi request reprint Characterization of mice with a combined suppression of I(to) and I(K,slow)
    M Brunner
    Cardiovascular Research Division, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA
    Am J Physiol Heart Circ Physiol 281:H1201-9. 2001
    ..Thus the attenuation of fast I(to) in addition to I(K,slow) in Kv1/Kv4DN mice causes significant prolongation of APD and Q-T intervals and attenuation of spontaneous arrhythmias...