David T Miller

Summary

Affiliation: Harvard University
Country: USA

Publications

  1. pmc Consensus statement: chromosomal microarray is a first-tier clinical diagnostic test for individuals with developmental disabilities or congenital anomalies
    David T Miller
    Division of Genetics and Department of Laboratory Medicine, Children s Hospital Boston and Harvard Medical School, Boston, MA, USA
    Am J Hum Genet 86:749-64. 2010
  2. pmc A prospective assessment of the Y402H variant in complement factor H, genetic variants in C-reactive protein, and risk of age-related macular degeneration
    Debra A Schaumberg
    Division of Preventive Medicine, Center for Cardiovascular Disease Prevention, Brigham and Women s Hospital, and Department of Ophthalmology, Schepens Eye Research Institute, Harvard Medical School, Boston, MA 02215, USA
    Invest Ophthalmol Vis Sci 47:2336-40. 2006
  3. doi request reprint Oligonucleotide microarrays for clinical diagnosis of copy number variation and zygosity status
    David T Miller
    Department of Laboratory Medicine, Division of Genetics, Children s Hospital Boston, and Harvard Medical School, Boston, Massachusetts, USA
    Curr Protoc Hum Genet . 2012
  4. ncbi request reprint Lack of association between genetic variation in 9 innate immunity genes and baseline CRP levels
    Piotr Kozlowski
    Division of Hematology, Brigham and Women s Hospital, Boston, MA 02115, USA
    Ann Hum Genet 70:574-86. 2006
  5. ncbi request reprint Development of a focused oligonucleotide-array comparative genomic hybridization chip for clinical diagnosis of genomic imbalance
    Yiping Shen
    Department of Laboratory Medicine, Children s Hospital Boston, Boston, MA 02115, USA
    Clin Chem 53:2051-9. 2007
  6. doi request reprint Association between microdeletion and microduplication at 16p11.2 and autism
    Lauren A Weiss
    Autism Consortium, Boston, USA
    N Engl J Med 358:667-75. 2008
  7. doi request reprint Oligonucleotide microarrays for clinical diagnosis of copy number variation
    David T Miller
    Department of Laboratory Medicine, Children s Hospital Boston, Boston, Massachusetts, USA
    Curr Protoc Hum Genet . 2008
  8. doi request reprint Clinical genetic testing for patients with autism spectrum disorders
    Yiping Shen
    Autism Consortium, Boston, Massachusetts, USA
    Pediatrics 125:e727-35. 2010
  9. pmc Deletions of NRXN1 (neurexin-1) predispose to a wide spectrum of developmental disorders
    Michael S L Ching
    Division of Developmental Medicine, Children s Hospital Boston, Boston, Massachusetts 02115, USA
    Am J Med Genet B Neuropsychiatr Genet 153:937-47. 2010

Collaborators

Detail Information

Publications9

  1. pmc Consensus statement: chromosomal microarray is a first-tier clinical diagnostic test for individuals with developmental disabilities or congenital anomalies
    David T Miller
    Division of Genetics and Department of Laboratory Medicine, Children s Hospital Boston and Harvard Medical School, Boston, MA, USA
    Am J Hum Genet 86:749-64. 2010
    ..G-banded karyotype analysis should be reserved for patients with obvious chromosomal syndromes (e.g., Down syndrome), a family history of chromosomal rearrangement, or a history of multiple miscarriages...
  2. pmc A prospective assessment of the Y402H variant in complement factor H, genetic variants in C-reactive protein, and risk of age-related macular degeneration
    Debra A Schaumberg
    Division of Preventive Medicine, Center for Cardiovascular Disease Prevention, Brigham and Women s Hospital, and Department of Ophthalmology, Schepens Eye Research Institute, Harvard Medical School, Boston, MA 02215, USA
    Invest Ophthalmol Vis Sci 47:2336-40. 2006
    ..Although plasma CRP levels have been related to AMD and plasma CRP levels are partly determined by genetic variation, there is no information on whether genetic variants in CRP are associated with AMD...
  3. doi request reprint Oligonucleotide microarrays for clinical diagnosis of copy number variation and zygosity status
    David T Miller
    Department of Laboratory Medicine, Division of Genetics, Children s Hospital Boston, and Harvard Medical School, Boston, Massachusetts, USA
    Curr Protoc Hum Genet . 2012
    ..Most clinical laboratories now offer arrays with some level of probe coverage throughout the genome, and many are offering detection of LCSH. Updated guidelines for array design and result interpretation are reviewed...
  4. ncbi request reprint Lack of association between genetic variation in 9 innate immunity genes and baseline CRP levels
    Piotr Kozlowski
    Division of Hematology, Brigham and Women s Hospital, Boston, MA 02115, USA
    Ann Hum Genet 70:574-86. 2006
    ....
  5. ncbi request reprint Development of a focused oligonucleotide-array comparative genomic hybridization chip for clinical diagnosis of genomic imbalance
    Yiping Shen
    Department of Laboratory Medicine, Children s Hospital Boston, Boston, MA 02115, USA
    Clin Chem 53:2051-9. 2007
    ..We report the design and validation of a focused oligonucleotide-array CGH assay for clinical laboratory diagnosis of genomic imbalance...
  6. doi request reprint Association between microdeletion and microduplication at 16p11.2 and autism
    Lauren A Weiss
    Autism Consortium, Boston, USA
    N Engl J Med 358:667-75. 2008
    ..Autism spectrum disorder is a heritable developmental disorder in which chromosomal abnormalities are thought to play a role...
  7. doi request reprint Oligonucleotide microarrays for clinical diagnosis of copy number variation
    David T Miller
    Department of Laboratory Medicine, Children s Hospital Boston, Boston, Massachusetts, USA
    Curr Protoc Hum Genet . 2008
    ..e., targeted versus whole genome). Array platform influences the likelihood of detecting variants of unknown significance. Clinical interpretation of such variants is discussed...
  8. doi request reprint Clinical genetic testing for patients with autism spectrum disorders
    Yiping Shen
    Autism Consortium, Boston, Massachusetts, USA
    Pediatrics 125:e727-35. 2010
    ..Current guidelines for clinical genetic testing recommend a G-banded karyotype to detect chromosomal abnormalities and fragile X DNA testing, but guidelines for chromosomal microarray analysis have not been established...
  9. pmc Deletions of NRXN1 (neurexin-1) predispose to a wide spectrum of developmental disorders
    Michael S L Ching
    Division of Developmental Medicine, Children s Hospital Boston, Boston, Massachusetts 02115, USA
    Am J Med Genet B Neuropsychiatr Genet 153:937-47. 2010
    ..Our study indicates that deletions of NRXN1 predispose to a wide spectrum of developmental disorders...