KARIN MICHELS

Summary

Affiliation: Harvard University
Country: USA

Publications

  1. pmc Polycarbonate bottle use and urinary bisphenol A concentrations
    Jenny L Carwile
    Department of Epidemiology, Harvard School of Public Health, Harvard University, Cambridge, Massachusetts, USA
    Environ Health Perspect 117:1368-72. 2009
  2. pmc Parental smoking in pregnancy and the risks of adult-onset hypertension
    Layla L de Jonge
    Department of Epidemiology, Erasmus Medical Center, Rotterdam, The Netherlands
    Hypertension 61:494-500. 2013
  3. pmc Body fatness during childhood and adolescence and incidence of breast cancer in premenopausal women: a prospective cohort study
    Heather J Baer
    Channing Laboratory, Department of Medicine, Brigham and Women s Hospital, Boston, Massachusetts, USA
    Breast Cancer Res 7:R314-25. 2005
  4. pmc Risk of breast cancer among daughters of mothers with diabetes: a population-based cohort study
    Olof Stephansson
    Clinical Epidemiology Unit, Department of Medicine, Solna, Karolinska University Hospital and Institute, T2, Stockholm, SE 171 76, Sweden
    Breast Cancer Res 12:R14. 2010
  5. ncbi request reprint Role of birthweight in the etiology of breast cancer
    Karin B Michels
    Obstetrics and Gynecology Epidemiology Center, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02115, USA
    Int J Cancer 119:2007-25. 2006
  6. ncbi request reprint The role of nutrition in cancer development and prevention
    Karin B Michels
    Obstetrics and Gynecology Epidemiology Center, Brigham and Women s Hospital, Harvard Medical School, 221 Longwood Avenue, Boston, MA 02115, USA
    Int J Cancer 114:163-5. 2005
  7. ncbi request reprint Diet and breast cancer: a review of the prospective observational studies
    Karin B Michels
    Obstetrics and Gynecology Epidemiology Center, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA
    Cancer 109:2712-49. 2007
  8. pmc Coffee, tea, and caffeine consumption and incidence of colon and rectal cancer
    Karin B Michels
    Obstetrics and Gynecology Epidemiology Center, Brigham and Women s Hospital, and Harvard Medical School, 221 Longwood Ave, Boston, MA 02115, USA
    J Natl Cancer Inst 97:282-92. 2005
  9. ncbi request reprint Fiber intake and incidence of colorectal cancer among 76,947 women and 47,279 men
    Karin B Michels
    Obstetrics and Gynecology Epidemiology Center, Department of Obstetrics and Gynecology, Brigham and Women s Hospital, Harvard Medical School, 221 Longwood Avenue, Boston, MA 02115, USA
    Cancer Epidemiol Biomarkers Prev 14:842-9. 2005
  10. ncbi request reprint Diet and cancer: current knowledge, methodologic pitfalls and future directions
    Karin B Michels
    Obstetrics and Gynecology Epidemiology Center, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02115, USA
    Int J Cancer 116:665-6. 2005

Collaborators

Detail Information

Publications78

  1. pmc Polycarbonate bottle use and urinary bisphenol A concentrations
    Jenny L Carwile
    Department of Epidemiology, Harvard School of Public Health, Harvard University, Cambridge, Massachusetts, USA
    Environ Health Perspect 117:1368-72. 2009
    ..Low-level concentrations of BPA in animals and possibly in humans may cause endocrine disruption. Whether ingestion of food or beverages from polycarbonate containers increases BPA concentrations in humans has not been studied...
  2. pmc Parental smoking in pregnancy and the risks of adult-onset hypertension
    Layla L de Jonge
    Department of Epidemiology, Erasmus Medical Center, Rotterdam, The Netherlands
    Hypertension 61:494-500. 2013
    ....
  3. pmc Body fatness during childhood and adolescence and incidence of breast cancer in premenopausal women: a prospective cohort study
    Heather J Baer
    Channing Laboratory, Department of Medicine, Brigham and Women s Hospital, Boston, Massachusetts, USA
    Breast Cancer Res 7:R314-25. 2005
    ..We examined prospectively the relation between body fatness during childhood and adolescence and the incidence of breast cancer in premenopausal women...
  4. pmc Risk of breast cancer among daughters of mothers with diabetes: a population-based cohort study
    Olof Stephansson
    Clinical Epidemiology Unit, Department of Medicine, Solna, Karolinska University Hospital and Institute, T2, Stockholm, SE 171 76, Sweden
    Breast Cancer Res 12:R14. 2010
    ..Diabetes during pregnancy is related to enhanced fetal growth, which has been associated with increased breast cancer risk. Whether daughters of mothers with a diagnosis of diabetes have an increased risk of breast cancer is not known...
  5. ncbi request reprint Role of birthweight in the etiology of breast cancer
    Karin B Michels
    Obstetrics and Gynecology Epidemiology Center, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02115, USA
    Int J Cancer 119:2007-25. 2006
    ..LOI of IGF2 has also been found in mammary tumor tissue. The role of environmental factors that stimulate such epigenetic regulation of gene expression remains to be elucidated...
  6. ncbi request reprint The role of nutrition in cancer development and prevention
    Karin B Michels
    Obstetrics and Gynecology Epidemiology Center, Brigham and Women s Hospital, Harvard Medical School, 221 Longwood Avenue, Boston, MA 02115, USA
    Int J Cancer 114:163-5. 2005
    ..Finally, epigenetic research is likely to contribute to the understanding of nutritional regulation of gene expression...
  7. ncbi request reprint Diet and breast cancer: a review of the prospective observational studies
    Karin B Michels
    Obstetrics and Gynecology Epidemiology Center, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA
    Cancer 109:2712-49. 2007
    ..The risk of breast cancer can be reduced by avoidance of weight gain in adulthood and limiting the consumption of alcohol...
  8. pmc Coffee, tea, and caffeine consumption and incidence of colon and rectal cancer
    Karin B Michels
    Obstetrics and Gynecology Epidemiology Center, Brigham and Women s Hospital, and Harvard Medical School, 221 Longwood Ave, Boston, MA 02115, USA
    J Natl Cancer Inst 97:282-92. 2005
    ..Cohort studies have not revealed such an association but were limited in size. We explored the association between consumption of coffee and tea and the incidence of colorectal cancer in two large prospective cohorts of women and men...
  9. ncbi request reprint Fiber intake and incidence of colorectal cancer among 76,947 women and 47,279 men
    Karin B Michels
    Obstetrics and Gynecology Epidemiology Center, Department of Obstetrics and Gynecology, Brigham and Women s Hospital, Harvard Medical School, 221 Longwood Avenue, Boston, MA 02115, USA
    Cancer Epidemiol Biomarkers Prev 14:842-9. 2005
    ....
  10. ncbi request reprint Diet and cancer: current knowledge, methodologic pitfalls and future directions
    Karin B Michels
    Obstetrics and Gynecology Epidemiology Center, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02115, USA
    Int J Cancer 116:665-6. 2005
  11. pmc Measurement of fruit and vegetable consumption with diet questionnaires and implications for analyses and interpretation
    Karin B Michels
    Obstetrics and Gynecology Epidemiology Center, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02115, USA
    Am J Epidemiol 161:987-94. 2005
    ....
  12. ncbi request reprint Self-administered semiquantitative food frequency questionnaires: patterns, predictors, and interpretation of omitted items
    Karin B Michels
    Department of Obstetrics, Gynecology and Reproductive Biology, Obstetrics and Gynecology Epidemiology Center, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts, USA
    Epidemiology 20:295-301. 2009
    ..Food items on a self-administered food frequency questionnaire (FFQ) may be left blank because the food was not consumed, because of difficulties remembering the frequency or amount of intake, or due to an oversight...
  13. doi request reprint The Women's Health Initiative Randomized Controlled Dietary Modification Trial: a post-mortem
    Karin B Michels
    Department of Obstetrics, Gynecology and Reproductive Biology, Obstetrics and Gynecology Epidemiology Center, Brigham and Women s Hospital, Harvard Medical School, 221 Longwood Avenue, Boston, MA 02115, USA
    Breast Cancer Res Treat 114:1-6. 2009
    ..The best information on prevention by diet and lifestyle will generally come from long-term prospective studies combined with controlled trials of intermediate endpoints...
  14. pmc A study of the importance of education and cost incentives on individual food choices at the Harvard School of Public Health cafeteria
    Karin B Michels
    Department of Epidemiology, Harvard School of Public Health, 677 Huntington Avenue, Boston, MA 02115, USA
    J Am Coll Nutr 27:6-11. 2008
    ..To investigate the importance of cost and awareness of health- or disease-promoting properties of foods and meals for choices by customers of a cafeteria...
  15. ncbi request reprint Preschool diet and adult risk of breast cancer
    Karin B Michels
    Obstetrics and Gynecology Epidemiology Center, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02115, USA
    Int J Cancer 118:749-54. 2006
    ..Further studies are needed to evaluate whether the association between preschool diet and breast cancer is reproducible in prospective data not subject to recall bias...
  16. ncbi request reprint Fruit and vegetable consumption and colorectal adenomas in the Nurses' Health Study
    Karin B Michels
    Obstetrics and Gynecology Epidemiology Center, Department of Obstetrics, Gynecology and Reproductive Biology, Brigham and Women s Hospital, 221 Longwood Avenue, Boston, MA 02115, USA
    Cancer Res 66:3942-53. 2006
    ..67; 95% CI, 0.51-0.90; P(trend) = 0.005). Frequent consumption of fruit may reduce the risk of colorectal adenomas...
  17. ncbi request reprint Longitudinal study of birthweight and the incidence of breast cancer in adulthood
    Karin B Michels
    Obstetrics and Gynecology Epidemiology Center, Channing Laboratory, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02115, USA
    Carcinogenesis 27:2464-8. 2006
    ..This association was independent of other factors operating later in life, except for adult height...
  18. ncbi request reprint A longitudinal study of infant feeding and obesity throughout life course
    K B Michels
    Obstetrics and Gynecology Epidemiology Center, Department of Obstetrics, Gynecology and Reproductive Biology, Brigham and Women s Hospital, Harvard Medical School, Boston, MA, USA
    Int J Obes (Lond) 31:1078-85. 2007
    ..We evaluated the relation between infant feeding and the development of overweight and obesity throughout life course...
  19. doi request reprint The promises and challenges of epigenetic epidemiology
    Karin B Michels
    Obstetrics and Gynecology Epidemiology Center, Department of Obstetrics, Gynecology and Reproductive Biology, Brigham and Women s Hospital, Harvard Medical School, Boston, MA, United States
    Exp Gerontol 45:297-301. 2010
    ..In particular, the tissue-specificity of epigenetic marks restricts epidemiologic studies of adequate size to easily accessible tissues...
  20. pmc The contribution of the environment (especially diet) to breast cancer risk
    Karin B Michels
    Epidemiology Center, Department of Obstetrics and Gynecology, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA
    Breast Cancer Res 4:58-61. 2002
    ....
  21. ncbi request reprint A prospective study of variety of healthy foods and mortality in women
    Karin B Michels
    Obstetrics and Gynecology Epidemiology Center, Brigham and Women s Hospital, Harvard Medical School, Harvard School of Public Health, Boston, MA, USA
    Int J Epidemiol 31:847-54. 2002
    ..The simplest way to describe dietary preferences is to separate foods considered beneficial to health from foods considered to promote disease, and separate individuals on the basis of their regular consumption of these foods...
  22. ncbi request reprint Being breastfed in infancy and breast cancer incidence in adult life: results from the two nurses' health studies
    K B Michels
    Channing Laboratory, Department of Medicine, Brigham and Women s Hospital, and Harvard Medical School, Boston, MA, USA
    Am J Epidemiol 153:275-83. 2001
    ..11 (95% CI: 0.88, 1.39) for women who were breastfed compared with those who were not. Data from these two large cohorts do not support the hypothesis that being breastfed confers protection against subsequent breast cancer...
  23. ncbi request reprint Hormone replacement therapy in epidemiologic studies and randomized clinical trials - are we checkmate?
    Karin B Michels
    Department of Epidemiology, Harvard School of Public Health, Boston, MA 02115, USA
    Epidemiology 14:3-5. 2003
  24. pmc Birthweight, maternal weight trajectories and global DNA methylation of LINE-1 repetitive elements
    Karin B Michels
    Obstetrics and Gynecology Epidemiology Center, Department of Obstetrics, Gynecology and Reproductive Biology, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts, United States of America
    PLoS ONE 6:e25254. 2011
    ..Future studies may elucidate whether chromosomal instabilities or other functional consequences of these changes contribute to the increased risk of chronic diseases among individuals with these characteristics...
  25. ncbi request reprint Early life predictors of chronic disease
    Karin B Michels
    Obstetrics and Gynecology Epidemiology Center, Brigham and Women s Hospital, Boston, Massachusetts 02115, USA
    J Womens Health (Larchmt) 12:157-61. 2003
    ..A life course approach to chronic disease prevention includes the study of maternal diet during pregnancy, intrauterine exposures, postnatal growth, and the adolescent period...
  26. ncbi request reprint Type 2 diabetes and subsequent incidence of breast cancer in the Nurses' Health Study
    Karin B Michels
    Obstetrics and Gynecology Epidemiology Center and Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA
    Diabetes Care 26:1752-8. 2003
    ..We prospectively evaluated the association between type 2 diabetes and invasive breast cancer incidence in the Nurses' Health Study...
  27. ncbi request reprint Update on unethical use of placebos in randomised trials
    Karin B Michels
    Department of Epidemiology, Harvard School of Public Health, 677 Huntington Avenue, Boston, MA 02115, USA
    Bioethics 17:188-204. 2003
    ..We suggest that the FDA's arguments defending their practice are insufficient to justify medical research that violates the Declaration of Helsinki...
  28. pmc Adult weight change and incidence of premenopausal breast cancer
    Karin B Michels
    Department of Obstetrics, Gynecology and Reproductive Biology, Obstetrics and Gynecology Epidemiology Center, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02115, USA
    Int J Cancer 130:902-9. 2012
    ....
  29. ncbi request reprint Caloric restriction and incidence of breast cancer
    Karin B Michels
    Obstetrics and Gynecology Epidemiology Center, Brigham and Women s Hospital, Harvard Medical School, Boston, Mass 02115, USA
    JAMA 291:1226-30. 2004
    ..Restricting caloric intake is one of the most effective ways to extend lifespan and to reduce spontaneous tumor occurrence in experimental animals, but whether similar associations hold in humans has not been appropriately studied...
  30. ncbi request reprint Hyperparathyroidism and subsequent incidence of breast cancer
    Karin B Michels
    Obstetrics and Gynecology Epidemiology Center, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02115, USA
    Int J Cancer 110:449-51. 2004
    ....
  31. ncbi request reprint The effect of correlated measurement error in multivariate models of diet
    Karin B Michels
    Obstetrics and Gynecology Epidemiology Center, Brigham and Women s Hospital, Harvard Medical School, Boston, MA, USA
    Am J Epidemiol 160:59-67. 2004
    ..Energy adjustment using regression residuals or energy density models led to improved parameter stability...
  32. ncbi request reprint Prospective study of fruit and vegetable consumption and incidence of colon and rectal cancers
    K B Michels
    Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, MA, USA
    J Natl Cancer Inst 92:1740-52. 2000
    ..Frequent consumption of fruit and vegetables has been associated with a reduced risk of colorectal cancer in many observational studies...
  33. ncbi request reprint Longitudinal study on the role of body size in premenopausal breast cancer
    Karin B Michels
    Department of Obstetrics and Gynecology, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02115, USA
    Arch Intern Med 166:2395-402. 2006
    ..A high body mass index (BMI) has been related to a reduced risk of breast cancer in premenopausal women. The mechanisms underlying this association have not been elucidated...
  34. pmc Lactation and incidence of premenopausal breast cancer: a longitudinal study
    Alison M Stuebe
    Division of Maternal Fetal Medicine, Department of Obstetrics and Gynecology, School of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, Massachusetts, USA
    Arch Intern Med 169:1364-71. 2009
    ..Findings from observational studies suggest an inverse association between lactation and premenopausal breast cancer risk, but results are inconsistent, and data from large prospective cohort studies are lacking...
  35. ncbi request reprint Coffee, tea, and caffeine consumption and breast cancer incidence in a cohort of Swedish women
    Karin B Michels
    Obstetrics and Gynecology Epidemiology Center, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02115, USA
    Ann Epidemiol 12:21-6. 2002
    ..Prior epidemiologic evidence has not supported an overall association between consumption of caffeinated beverages and risk of breast cancer, but consumption in some studies was low...
  36. ncbi request reprint A prospective study of breast size and premenopausal breast cancer incidence
    Aaron S Kusano
    Department of Epidemiology, Harvard School of Public Health, and Obstetrics and Gynecology Epidemiology Center, Brigham and Women s Hospital, Boston, MA 02115, USA
    Int J Cancer 118:2031-4. 2006
    ..Stratifying by BMI at age 18 at a cutoff point of 21 kg/m2 gave similar results. Larger bra cup size at a young age is associated with a higher incidence of premenopausal breast cancer, though this association is limited to leaner women...
  37. ncbi request reprint Diabetes, metabolic syndrome, and breast cancer: a review of the current evidence
    Fei Xue
    Obstetrics and Gynecology Epidemiology Center, Brigham and Women s Hospital, Harvard Medical School, Boston, MA, USA
    Am J Clin Nutr 86:s823-35. 2007
    ....
  38. ncbi request reprint Parental characteristics as predictors of birthweight
    Fei Xue
    Obstetrics and Gynecology Epidemiology Center, Department of Obstetrics, Gynecology and Reproductive Biology, Brigham and Women s Hospital, Harvard Medical School, 221 Longwood Avenue, Boston, MA 02115, USA
    Hum Reprod 23:168-77. 2008
    ..Previous studies provided conflicting results on the relevance of parental characteristics for offspring's size at birth. The objective of this study was to investigate parental predictors of birthweight...
  39. ncbi request reprint Intrauterine factors and risk of breast cancer: a systematic review and meta-analysis of current evidence
    Fei Xue
    Obstetrics and Gynecology Epidemiology Center, Department of Obstetrics, Gynecology and Reproductive Biology, Brigham and Women s Hospital, Harvard Medical School, Boston, MA, USA
    Lancet Oncol 8:1088-100. 2007
    ..We reviewed and summarised quantitatively the available data on intrauterine exposures and risk of breast cancer...
  40. pmc Measurement error correction for nutritional exposures with correlated measurement error: use of the method of triads in a longitudinal setting
    Bernard Rosner
    Channing Laboratory, Harvard Medical School, Boston, MA, USA
    Stat Med 27:3466-89. 2008
    ....
  41. pmc Observational studies analyzed like randomized experiments: an application to postmenopausal hormone therapy and coronary heart disease
    Miguel A Hernán
    Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts, USA
    Epidemiology 19:766-79. 2008
    ..Observational studies had previously suggested reduced CHD risk in hormone users...
  42. ncbi request reprint Exposure to cigarette smoke in utero: comparison of reports from mother and daughter
    Julia F Simard
    Department of Epidemiology, Harvard School of Public Health, Boston, MA 02115, USA
    Epidemiology 19:628-33. 2008
    ..To study the role of in utero smoking exposure in offsprings' adult health outcomes, it may be necessary to rely upon reports by the offspring themselves...
  43. pmc Infant feeding and the incidence of endometrial cancer
    Fei Xue
    Obstetrics and Gynecology Epidemiology Center, Brigham and Women s Hospital, 221 Longwood Avenue, Boston, MA 02115, USA
    Cancer Epidemiol Biomarkers Prev 17:1316-21. 2008
    ..Having been breast-fed was not associated with the incidence of endometrial cancer in this cohort, but statistical power for analyses restricted to premenopausal women was limited...
  44. pmc Validity of maternal recall of preschool diet after 43 years
    Jorge E Chavarro
    Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02115, USA
    Am J Epidemiol 169:1148-57. 2009
    ..27; range, -0.14 to 0.85). Correlations for nutrient intakes were consistently low (median, 0.06; range, -0.35 to 0.27). Overall, the FFQ did not validly reflect overall preschool diet when completed by mothers 4 decades later...
  45. pmc Cigarette smoking and the incidence of breast cancer
    Fei Xue
    Obstetrics and Gynecology Epidemiology Center, Department of Obstetrics and Gynecology, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02115, USA
    Arch Intern Med 171:125-33. 2011
    ..Conversely, cigarette smoking also has antiestrogenic effects, which may reduce the risk of BC. The association between smoking and BC remains controversial...
  46. doi request reprint Green tea consumption and breast cancer risk or recurrence: a meta-analysis
    Adeyemi A Ogunleye
    Department of Epidemiology, Harvard School of Public Health, 677, Huntington Avenue, Boston, MA, USA
    Breast Cancer Res Treat 119:477-84. 2010
    ..The association between green tea consumption and breast cancer incidence remains unclear based on the current evidence...
  47. pmc Caffeine consumption during pregnancy and risk of preterm birth: a meta-analysis
    Ekaterina Maslova
    Department of Nutrition, Harvard School of Public Health, Boston, MA 02115, USA
    Am J Clin Nutr 92:1120-32. 2010
    ..The effect of caffeine intake during pregnancy on the risk of preterm delivery has been studied for the past 3 decades with inconsistent results...
  48. pmc Menstrual cycle characteristics and incidence of premenopausal breast cancer
    Kathryn L Terry
    Obstetrics and Gynecology Epidemiology Center, Harvard School of Public Health, Brigham and Women s Hospital, 221 Longwood Avenue, Boston, Massachusetts 02115, USA
    Cancer Epidemiol Biomarkers Prev 14:1509-13. 2005
    ..Anovulation, which is more common with long or irregular cycles, has been hypothesized to reduce the incidence of breast cancer...
  49. pmc Longitudinal study of birth weight and adult body mass index in predicting risk of coronary heart disease and stroke in women
    Janet W Rich-Edwards
    Department of Ambulatory Care and Prevention, Harvard Medical School and Harvard Pilgrim Health Care, 133 Brookline Avenue, Boston, MA 02215, USA
    BMJ 330:1115. 2005
    ..To determine whether birth weight and adult body size interact to predict coronary heart disease in women, as has been observed for men. To determine whether birth weight and adult body size interact to predict risk of stroke...
  50. pmc Adult recall of adolescent diet: reproducibility and comparison with maternal reporting
    Sonia S Maruti
    Channing Laboratory, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston 02215, MA, USA
    Am J Epidemiol 161:89-97. 2005
    ..30 (range, 0.10-0.61). While further studies are warranted, these findings imply that this food frequency questionnaire provides a reasonable record of adolescent diet...
  51. ncbi request reprint In utero exposures and the incidence of endometriosis
    Stacey A Missmer
    Channing Laboratory, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, Massachusetts 02115, USA
    Fertil Steril 82:1501-8. 2004
    ..To investigate the relation between the fetal environment and endometriosis...
  52. ncbi request reprint Smoking and other lifestyle factors and the risk of Graves' hyperthyroidism
    Ingrid A Holm
    Division of Genetics, Department of Medicine, Children s Hospital, Boston, MA 02115, USA
    Arch Intern Med 165:1606-11. 2005
    ..We sought to determine whether lifestyle factors, including smoking, alcohol consumption, physical activity level, and body mass index, are risk factors for Graves' hyperthyroidism...
  53. ncbi request reprint Duration of lactation and incidence of type 2 diabetes
    Alison M Stuebe
    Department of Obstetrics, Gynecology, and Reproductive Biology, Brigham and Women s Hospital, and Harvard Medical School, Boston, Mass 02115, USA
    JAMA 294:2601-10. 2005
    ..Lactation is associated with improved glucose and insulin homeostasis, independent of weight change...
  54. ncbi request reprint A prospective study on habitual duration of sleep and incidence of breast cancer in a large cohort of women
    Simone P Pinheiro
    Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts, USA
    Cancer Res 66:5521-5. 2006
    ..05). In this prospective study, we found no convincing evidence for an association between sleep duration and the incidence of breast cancer...
  55. ncbi request reprint Adult height, age at attained height, and incidence of breast cancer in premenopausal women
    Heather J Baer
    Channing Laboratory, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02115, USA
    Int J Cancer 119:2231-5. 2006
    ..65). These results confirm previous findings that taller adult height is associated with increased risk of premenopausal breast cancer but do not provide evidence that age at attained height is related to risk...
  56. pmc Validity of adolescent diet recall 48 years later
    Jorge E Chavarro
    Department of Nutrition, Harvard School of Public Health, Boston, MA 02115, USA
    Am J Epidemiol 170:1563-70. 2009
    ..However, this food frequency questionnaire did not validly measure overall adolescent diet when completed by middle-aged and older adults on average 48 years after adolescence...
  57. ncbi request reprint Birthweight and body size throughout life in relation to sex hormones and prolactin concentrations in premenopausal women
    Shelley S Tworoger
    Channing Laboratory, 181 Longwood Avenue, 3rd Floor, Boston, MA 02115, USA
    Cancer Epidemiol Biomarkers Prev 15:2494-501. 2006
    ..Our results suggest that effects on premenopausal sex hormone levels may be one mechanism through which adult adiposity, but not birthweight or childhood body size, affects premenopausal breast cancer risk...
  58. ncbi request reprint Breastfeeding during infancy and the risk of cardiovascular disease in adulthood
    Janet W Rich-Edwards
    Department of Ambulatory Care and Prevention, Harvard Medical School and Harvard Pilgrim Health Care, Boston, Massachusetts 02215, USA
    Epidemiology 15:550-6. 2004
    ..Only 2 studies have evaluated the relation between having been breastfed and the risk of adult cardiovascular events...
  59. ncbi request reprint A prospective study of infertility due to ovulatory disorders, ovulation induction, and incidence of breast cancer
    Kathryn L Terry
    Department of Epidemiology, Harvard School of Public Health, Boston, MA, USA
    Arch Intern Med 166:2484-9. 2006
    ..Anovulation has been hypothesized to decrease the risk of breast cancer. Therefore, infertility attributed to ovulatory disorders and ovulation-induction therapy may influence breast cancer risk...
  60. ncbi request reprint Parental age at delivery and incidence of breast cancer: a prospective cohort study
    Fei Xue
    Obstetrics and Gynecology Epidemiology Center, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02115, USA
    Breast Cancer Res Treat 104:331-40. 2007
    ..Studies on parental age at delivery in relation to breast cancer risk have had mixed results, but prospective data are limited. No study has explored the associations with subtypes of breast cancer defined by hormonal receptor status...
  61. ncbi request reprint Induced and spontaneous abortion and incidence of breast cancer among young women: a prospective cohort study
    Karin B Michels
    Obstetrics and Gynecology Epidemiology Center, Department of Obstetrics and Gynecology, Brigham and Women s Hospital, Harvard Medical School, Boston, Mass 02115, USA
    Arch Intern Med 167:814-20. 2007
    ..Retrospective cohort studies using registry information in Scandinavia have not suggested an increase in the incidence of breast cancer, although data on individual reproductive factors were not accounted for...
  62. pmc Maternal pregnancy-related hypertension and risk for hypertension in offspring later in life
    Kristin Palmsten
    Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts, USA
    Obstet Gynecol 116:858-64. 2010
    ..To estimate the association between maternal pregnancy-related hypertension and offspring hypertension later in life in a birth cohort from New England...
  63. pmc Prenatal and perinatal factors and risk of multiple sclerosis
    Hannah Gardener
    Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts, USA
    Epidemiology 20:611-8. 2009
    ..A potential role of prenatal and perinatal exposures in autoimmunity has been hypothesized, but few studies have examined the relation between various prenatal and perinatal factors and the risk of multiple sclerosis (MS)...
  64. ncbi request reprint Dads as breastfeeding advocates: results from a randomized controlled trial of an educational intervention
    Adam J Wolfberg
    Department of Obstetrics and Gynecology, Brigham and Women s Hospital, Harvard Medical School, Boston, Mass 02115, USA
    Am J Obstet Gynecol 191:708-12. 2004
    ....
  65. pmc Duration of lactation and incidence of myocardial infarction in middle to late adulthood
    Alison M Stuebe
    Division of Maternal Fetal Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, MA, USA
    Am J Obstet Gynecol 200:138.e1-8. 2009
    ..We assessed the relation between duration of lactation and maternal incident myocardial infarction...
  66. pmc Body fat distribution and risk of premenopausal breast cancer in the Nurses' Health Study II
    Holly R Harris
    Department of Epidemiology, Harvard School of Public Health, Boston, MA, USA
    J Natl Cancer Inst 103:273-8. 2011
    ..01) for waist to hip ratio. Our findings suggest that body fat distribution does not play an important role in the overall incidence of premenopausal breast cancer but is associated with an increased risk for ER-negative breast cancer...
  67. doi request reprint Birth weight and childhood leukemia: a meta-analysis and review of the current evidence
    Robert W Caughey
    Department of Epidemiology, Harvard School of Public Health, Boston, MA, USA
    Int J Cancer 124:2658-70. 2009
    ..For AML the risk may be elevated at both high and low extremes of birth weight, suggesting a U-shaped association...
  68. ncbi request reprint Nutritional epidemiology--past, present, future
    Karin B Michels
    Int J Epidemiol 32:486-8. 2003
  69. ncbi request reprint The women's health initiative--curse or blessing?
    Karin B Michels
    Int J Epidemiol 35:814-6. 2006
  70. ncbi request reprint Breast cancer--early life matters
    Karin B Michels
    N Engl J Med 351:1679-81. 2004
  71. pmc Breast size and risk of type 2 diabetes mellitus
    Joel G Ray
    Departments of Medicine, and the Li Ka Shing Knowledge Institute, St Michael s Hospital, University of Toronto, Toronto, Ont
    CMAJ 178:289-95. 2008
    ..We sought to evaluate whether a woman's breast size in late adolescence is associated with an increased risk of type 2 diabetes mellitus in adulthood...
  72. ncbi request reprint Environmental pollutants, diet, physical activity, body size, and breast cancer: where do we stand in research to identify opportunities for prevention?
    Julia Green Brody
    Silent Spring Institute, Newton, Massachusetts 02458, USA
    Cancer 109:2627-34. 2007
    ..Investments in research on environmental factors in breast cancer have potentially large public health benefits...
  73. ncbi request reprint Chromatin fluorescence characteristics and standard semen analysis parameters: correlations observed in andrology testing among 136 males referred for infertility evaluation
    E Scott Sills
    Georgia Reproductive Specialists LLC, Atlanta, GA 30342, USA
    J Obstet Gynaecol 24:74-7. 2004
    ..Additionally, SCSA data may offer explanations for previous miscarriage, providing closure for some couples contemplating future use of anonymous donor sperm...
  74. ncbi request reprint Postmenopausal hormone therapy: a reversal of fortune
    Karin B Michels
    Circulation 107:1830-3. 2003
  75. ncbi request reprint A maternalistic approach to prevention
    Karin B Michels
    Int J Epidemiol 34:3-4. 2005
  76. ncbi request reprint Epigenetic epidemiology of the developmental origins hypothesis
    Robert A Waterland
    Department of Pediatrics, USDA Children s Nutrition Research Center, Baylor College of Medicine, Houston, TX, USA
    Annu Rev Nutr 27:363-88. 2007
    ....
  77. doi request reprint The promise and challenges of population strategies of prevention
    Karin B Michels
    Int J Epidemiol 37:914-6. 2008
  78. ncbi request reprint Estimating treatment effects from observational data: dissonant and resonant notes from the SYMPHONY trials
    Karin B Michels
    JAMA 287:3130-2. 2002

Research Grants10

  1. Epigenetic Changes After Intrauterine Exposure to Endocrine Disrupting Chemicals
    KARIN MICHELS; Fiscal Year: 2007
    ....
  2. METHODOLOGIC ISSUES IN NUTRITIONAL EPIDEMIOLOGY
    KARIN MICHELS; Fiscal Year: 2000
    ..We aim to provide guidance to researchers who wish to explore diet-disease relations in how to use data best to obtain most valid results and avoid pitfalls which might produce misleading associations. ..
  3. Maternal obesity, intrauterine gene expression and breast cancer
    KARIN MICHELS; Fiscal Year: 2007
    ....
  4. Lifetime body weight and premenopausal breast cancer
    KARIN MICHELS; Fiscal Year: 2007
    ..It is also highly efficient since it borrows from questionnaire data, blood samples, and mammograms already collected for the NHS II. ..
  5. Lifetime body weight and premenopausal breast cancer
    KARIN MICHELS; Fiscal Year: 2006
    ..It is also highly efficient since it borrows from questionnaire data, blood samples, and mammograms already collected for the NHS II. ..
  6. Validation of Preschool and High School Diet Recall
    KARIN MICHELS; Fiscal Year: 2006
    ..Lastly we will determine whether the validity of recall depends on characteristics such as time between diet record and FFQ, number of children, gender of the subject, and nutritional status. ..
  7. METHODOLOGIC ISSUES IN NUTRITIONAL EPIDEMIOLOGY
    KARIN MICHELS; Fiscal Year: 2002
    ..We aim to provide guidance to researchers who wish to explore diet-disease relations in how to use data best to obtain most valid results and avoid pitfalls which might produce misleading associations. ..
  8. METHODOLOGIC ISSUES IN NUTRITIONAL EPIDEMIOLOGY
    KARIN MICHELS; Fiscal Year: 2001
    ..We aim to provide guidance to researchers who wish to explore diet-disease relations in how to use data best to obtain most valid results and avoid pitfalls which might produce misleading associations. ..