Linda J Metzger
Affiliation: Harvard University
- Event-related potentials to auditory stimuli in female Vietnam nurse veterans with posttraumatic stress disorderLinda J Metzger
Veterans Affairs Medical Center, Manchester, New Hampshire, USA
Psychophysiology 39:49-63. 2002..Future research is needed to determine whether the opposite ERP abnormalities observed in this PTSD sample reflect gender-, trauma-, or sample-specific findings...
- PTSD arousal and depression symptoms associated with increased right-sided parietal EEG asymmetryLinda J Metzger
Veterans Affairs Medical Center Research Service, Manchester, NH 03104, USA
J Abnorm Psychol 113:324-9. 2004..These findings underscore the importance of isolating, both theoretically and statistically, emotional subcomponents in studies of regional brain activation...
- Subtle neurologic compromise as a vulnerability factor for combat-related posttraumatic stress disorder: results of a twin studyTamara V Gurvits
Research Service, Veterans Affairs Medical Center, Manchester, NH, USA
Arch Gen Psychiatry 63:571-6. 2006..Previous studies have demonstrated subtle neurologic dysfunction in chronic posttraumatic stress disorder (PTSD) manifest as increased neurologic soft signs (NSSs). The origin of this dysfunction is undetermined...
- Event-related potentials to auditory stimuli in monozygotic twins discordant for combat: association with PTSDLinda J Metzger
Veterans Affairs Medical Center, Manchester, New Hampshire 03104, USA
Psychophysiology 46:172-8. 2009..Results replicate increased N2 latency and diminished P3b amplitude in PTSD and suggest that diminished P3b amplitude is an acquired condition in PTSD...
- Intensity dependence of auditory P2 in monozygotic twins discordant for Vietnam combat: associations with posttraumatic stress disorderLinda J Metzger
Research Service, Department of Veterans Affairs VA Medical Center, Manchester, NH 03104, USA
J Rehabil Res Dev 45:437-49. 2008..Inspection of group means suggests that the observed increased P2 intensity dependence is a consequence of PTSD. Our findings further suggest that low serotonergic tone may emerge as one potential consequence of this disorder...
- Basal and suppressed salivary cortisol in female Vietnam nurse veterans with and without PTSDLinda J Metzger
Research Service, VA Medical Center, Research Service 151, Manchester, NH 03104, United States
Psychiatry Res 161:330-5. 2008....
- Effects of beta blockade, PTSD diagnosis, and explicit threat on the extinction and retention of an aversively conditioned responseScott P Orr
Department of Veterans Affairs Medical Center, Research Service 151, 718 Smyth Road, Manchester, NH 03104, United States
Biol Psychol 73:262-71. 2006..This suggests that belief in the presence of a threat is necessary and sufficient for activating a previously established CR...
- Physiologic reactivity to startling tones in female Vietnam nurse veterans with PTSDMargaret A Carson
Department of Nursing, Saint Anselm College, Manchester, NH 03102 1310, USA
J Trauma Stress 20:657-66. 2007..A larger HR response to loud tones is one of the most robust physiologic findings in PTSD and may reflect increased defensive responding...
- Performance on visuospatial copying tasks in individuals with chronic posttraumatic stress disorderTamara V Gurvits
VA Research Service, 718 Smyth Rd, Manchester, NH 03104, USA
Psychiatry Res 112:263-8. 2002..These findings are consistent with pre-trauma visual-spatial impairment as being among the risk factors for chronic PTSD...
- Clarifying the origin of biological abnormalities in PTSD through the study of identical twins discordant for combat exposureRoger K Pitman
Massachusetts General Hospital, Room 2616, Bldg 149, 13th St, Charlestown, MA 02129, USA
Ann N Y Acad Sci 1071:242-54. 2006..These results support the conclusion that the latter abnormalities represent antecedent, familial vulnerability factors for developing chronic PTSD upon exposure to a traumatic event...
- Physiologic responses to sudden, loud tones in monozygotic twins discordant for combat exposure: association with posttraumatic stress disorderScott P Orr
Department of Psychiatry, Massachusetts General Hospital and Harvard Medical School, Boston, USA
Arch Gen Psychiatry 60:283-8. 2003..Studying identical twins discordant for traumatic exposure offers an opportunity to resolve these competing origins...
- Psychophysiology of post-traumatic stress disorderScott P Orr
Department of Psychiatry, Harvard Medical School, Massachusetts General Hospital, Charlestown, MA 02129, USA
Psychiatr Clin North Am 25:271-93. 2002..We hope that the broad range of psychophysiologic investigations and findings in PTSD will inspire others to consider possible applications of these methodologies to their own clinical and research endeavors...
- Regional cerebral blood flow in the amygdala and medial prefrontal cortex during traumatic imagery in male and female Vietnam veterans with PTSDLisa M Shin
Department of Psychology, Tufts University, Medford, MA 02155, USA
Arch Gen Psychiatry 61:168-76. 2004..However, the functional relationship between these brain regions in PTSD has not been directly examined...