Lotfi Merabet

Summary

Affiliation: Harvard University
Country: USA

Publications

  1. ncbi request reprint Transcranial magnetic stimulation as an investigative tool in the study of visual function
    Lotfi B Merabet
    Laboratory for Magnetic Brain Stimulation, Department of Neurology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, USA
    Optom Vis Sci 80:356-68. 2003
  2. pmc Functional recruitment of visual cortex for sound encoded object identification in the blind
    Lotfi B Merabet
    Department of Neurology, Berenson Allen Center for Noninvasive Brain Stimulation, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA
    Neuroreport 20:132-8. 2009
  3. pmc Neuroplasticity associated with tactile language communication in a deaf-blind subject
    Souzana Obretenova
    The Berenson Allen Center for Noninvasive Brain Stimulation, Department of Neurology, Beth Israel Deaconess Medical Center, Harvard Medical School Boston, MA, USA
    Front Hum Neurosci 3:60. 2010
  4. ncbi request reprint Combined activation and deactivation of visual cortex during tactile sensory processing
    Lotfi B Merabet
    Department of Neurology, Beth Israel Deaconess Medical Center, 330 Brookline Avenue, KS 430, Boston, MA 02215, USA
    J Neurophysiol 97:1633-41. 2007
  5. ncbi request reprint What blindness can tell us about seeing again: merging neuroplasticity and neuroprostheses
    Lotfi B Merabet
    Department of Ophthalmology, Center for Noninvasive Brain Stimulation, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts 02215, USA
    Nat Rev Neurosci 6:71-7. 2005
  6. pmc Neural reorganization following sensory loss: the opportunity of change
    Lotfi B Merabet
    Berenson Allen Center for Noninvasive Brain Stimulation, Department of Neurology, Beth Israel Deaconess Medical Center, Harvard Medical School, KS 158 Boston, Massachusetts 02215, USA
    Nat Rev Neurosci 11:44-52. 2010
  7. ncbi request reprint 'Who is the ideal candidate?': decisions and issues relating to visual neuroprosthesis development, patient testing and neuroplasticity
    Lotfi B Merabet
    Department of Neurology, Center for Noninvasive Brain Stimulation, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA
    J Neural Eng 4:S130-5. 2007
  8. ncbi request reprint Shape conveyed by visual-to-auditory sensory substitution activates the lateral occipital complex
    Amir Amedi
    Berenson Allen Center for Noninvasive Brain Stimulation, Department of Neurology, Beth Israel Deaconess Medical Center, Harvard Medical School, 330 Brookline Ave, Boston, Massachusetts 02115, USA
    Nat Neurosci 10:687-9. 2007
  9. ncbi request reprint Feeling by sight or seeing by touch?
    Lotfi Merabet
    Laboratory for Magnetic Brain Stimulation, Beth Israel Deaconess Medical Center, Harvard Medical School, 330 Brookline Avenue, Boston, MA 02215, USA
    Neuron 42:173-9. 2004
  10. ncbi request reprint Behavioral and neuroplastic changes in the blind: evidence for functionally relevant cross-modal interactions
    Hugo Theoret
    Laboratory for Magnetic Brain Stimulation, Department of Neurology, Beth Israel Deaconess Medical Center, Harvard Medical School, 330 Brookline Avenue, Boston, MA 02215, USA
    J Physiol Paris 98:221-33. 2004

Research Grants

Detail Information

Publications23

  1. ncbi request reprint Transcranial magnetic stimulation as an investigative tool in the study of visual function
    Lotfi B Merabet
    Laboratory for Magnetic Brain Stimulation, Department of Neurology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, USA
    Optom Vis Sci 80:356-68. 2003
    ..The application of TMS in the diagnosis as well as possible therapeutic use in various visual disorders is also discussed...
  2. pmc Functional recruitment of visual cortex for sound encoded object identification in the blind
    Lotfi B Merabet
    Department of Neurology, Berenson Allen Center for Noninvasive Brain Stimulation, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA
    Neuroreport 20:132-8. 2009
    ....
  3. pmc Neuroplasticity associated with tactile language communication in a deaf-blind subject
    Souzana Obretenova
    The Berenson Allen Center for Noninvasive Brain Stimulation, Department of Neurology, Beth Israel Deaconess Medical Center, Harvard Medical School Boston, MA, USA
    Front Hum Neurosci 3:60. 2010
    ..Finally, the resilience of language function within the context of early and combined visual and auditory deprivation may be related to enhanced connectivity between relevant cortical areas...
  4. ncbi request reprint Combined activation and deactivation of visual cortex during tactile sensory processing
    Lotfi B Merabet
    Department of Neurology, Beth Israel Deaconess Medical Center, 330 Brookline Avenue, KS 430, Boston, MA 02215, USA
    J Neurophysiol 97:1633-41. 2007
    ....
  5. ncbi request reprint What blindness can tell us about seeing again: merging neuroplasticity and neuroprostheses
    Lotfi B Merabet
    Department of Ophthalmology, Center for Noninvasive Brain Stimulation, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts 02215, USA
    Nat Rev Neurosci 6:71-7. 2005
    ..However, success in developing functional visual prostheses requires an understanding of how to communicate effectively with the visually deprived brain in order to merge what is perceived visually with what is generated electrically...
  6. pmc Neural reorganization following sensory loss: the opportunity of change
    Lotfi B Merabet
    Berenson Allen Center for Noninvasive Brain Stimulation, Department of Neurology, Beth Israel Deaconess Medical Center, Harvard Medical School, KS 158 Boston, Massachusetts 02215, USA
    Nat Rev Neurosci 11:44-52. 2010
    ..Here, we discuss crossmodal neuroplasticity with regards to behavioural adaptation after sensory deprivation and highlight the possibility of maladaptive consequences within the context of rehabilitation...
  7. ncbi request reprint 'Who is the ideal candidate?': decisions and issues relating to visual neuroprosthesis development, patient testing and neuroplasticity
    Lotfi B Merabet
    Department of Neurology, Center for Noninvasive Brain Stimulation, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA
    J Neural Eng 4:S130-5. 2007
    ..Specifically, an understanding of the adaptive and compensatory changes that occur within the brain could assist in guiding the development of post-implantation rehabilitative strategies and optimize behavioral outcomes...
  8. ncbi request reprint Shape conveyed by visual-to-auditory sensory substitution activates the lateral occipital complex
    Amir Amedi
    Berenson Allen Center for Noninvasive Brain Stimulation, Department of Neurology, Beth Israel Deaconess Medical Center, Harvard Medical School, 330 Brookline Ave, Boston, Massachusetts 02115, USA
    Nat Neurosci 10:687-9. 2007
    ..Recognizing objects by their typical sounds or learning to associate specific soundscapes with specific objects do not activate this region. This suggests that LOtv is driven by the presence of shape information...
  9. ncbi request reprint Feeling by sight or seeing by touch?
    Lotfi Merabet
    Laboratory for Magnetic Brain Stimulation, Beth Israel Deaconess Medical Center, Harvard Medical School, 330 Brookline Avenue, Boston, MA 02215, USA
    Neuron 42:173-9. 2004
    ..The differential effect of rTMS on task performance and corroborative clinical evidence suggest that occipital cortex is engaged in tactile tasks requiring fine spatial discrimination...
  10. ncbi request reprint Behavioral and neuroplastic changes in the blind: evidence for functionally relevant cross-modal interactions
    Hugo Theoret
    Laboratory for Magnetic Brain Stimulation, Department of Neurology, Beth Israel Deaconess Medical Center, Harvard Medical School, 330 Brookline Avenue, Boston, MA 02215, USA
    J Physiol Paris 98:221-33. 2004
    ..These issues have important implications for the development of visual prosthesis aimed at restoring some degree of vision in the blind...
  11. ncbi request reprint Modulation of right motor cortex excitability without awareness following presentation of masked self-images
    Hugo Theoret
    Laboratory for Magnetic Brain Stimulation, Behavioral Neurology Unit, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, USA
    Brain Res Cogn Brain Res 20:54-7. 2004
    ..These results demonstrate the utility of TMS to probe unconscious processing and support the notion of hemispheric asymmetry in the processing of self-images...
  12. ncbi request reprint Modulation in motor threshold after a severe episode of gastrointestinal distress
    Felipe Fregni
    Laboratory for Magnetic Brain Stimulation, Department of Neurology, Beth Israel Deaconess Medical Center, Boston, MA 02215, USA
    J ECT 20:50-1. 2004
  13. pmc High-resolution modeling assisted design of customized and individualized transcranial direct current stimulation protocols
    Marom Bikson
    Department of Biomedical Engineering, The City College of New York of CUNY, New York, NY 10031, USA
    Neuromodulation 15:306-15. 2012
    ..The aim of this review is to discuss the incorporation of high-resolution patient-specific computer modeling to guide and optimize tDCS...
  14. ncbi request reprint The plastic human brain cortex
    Alvaro Pascual-Leone
    Center for Non Invasive Brain Stimulation, Department of Neurology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA
    Annu Rev Neurosci 28:377-401. 2005
    ..The challenge we face is to learn enough about the mechanisms of plasticity to modulate them to achieve the best behavioral outcome for a given subject...
  15. ncbi request reprint Effects of complete monocular deprivation in visuo-spatial memory
    Zaira Cattaneo
    Department of Psychology, University of Pavia, Pavia, Italy
    Brain Res Bull 77:112-6. 2008
    ..No difference was observed between the monocular and binocular viewing control groups, suggesting that early monocular deprivation affects the development of cortical mechanisms mediating visuo-spatial cognition...
  16. ncbi request reprint Occipital transcranial magnetic stimulation has opposing effects on visual and auditory stimulus detection: implications for multisensory interactions
    Vincenzo Romei
    Functional Brain Mapping Laboratory, Department of Neurology, University Hospital Geneva, 1211 Geneva, Switzerland
    J Neurosci 27:11465-72. 2007
    ..The collective data support a mechanism of early auditory-visual interactions that is mediated by auditory-driven sensitivity changes in visual neurons that coincide in time with the initial volleys of visual input...
  17. ncbi request reprint Time-dependent changes in cortical excitability after prolonged visual deprivation
    Naomi B Pitskel
    Department of Neurology, Berenson Allen Center for Noninvasive Brain Stimulation, Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA
    Neuroreport 18:1703-7. 2007
    ..Thus, light deprivation is characterized by a transient increase in visual cortical excitability, followed by a sustained decrease in visual cortex excitability that quickly returns to baseline levels after re-exposure to light...
  18. ncbi request reprint Dissociable networks for the expectancy and perception of emotional stimuli in the human brain
    Felix Bermpohl
    Center for Non Invasive Brain Stimulation, Department of Neurology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02132, USA
    Neuroimage 30:588-600. 2006
    ..This dissociation may reflect a distinction between anticipatory and perceptive components of emotional stimulus processing...
  19. ncbi request reprint Visual topography of human intraparietal sulcus
    Jascha D Swisher
    Perceptual Neuroimaging Laboratory, Program in Neuroscience and Department of Psychology, Boston University, Boston, Massachusetts 02215, USA
    J Neurosci 27:5326-37. 2007
    ..These visual maps may provide a practical framework in which to characterize the functional organization of human IPS...
  20. ncbi request reprint Visual phosphene perception modulated by subthreshold crossmodal sensory stimulation
    Ciro Ramos-Estebanez
    Berenson Allen Center for Noninvasive Brain Stimulation, Department of Neurology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts 02115, USA
    J Neurosci 27:4178-81. 2007
    ..These interactions may reflect an underlying anatomical connectivity and become further enhanced by attention modulation mechanisms...
  21. ncbi request reprint Visual hallucinations during prolonged blindfolding in sighted subjects
    Lotfi B Merabet
    Laboratory for Magnetic Brain Stimulation, Department of Neurology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts 02115, USA
    J Neuroophthalmol 24:109-13. 2004
    ..Subjects were insightful as to their unreal nature. These results indicate that rapid and complete visual deprivation is sufficient to induce visual hallucinations in normal subjects...
  22. ncbi request reprint Suppression of complex visual hallucinatory experiences by occipital transcranial magnetic stimulation: a case report
    Lotfi B Merabet
    Laboratory for Magnetic Brain Stimulation, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA
    Neurocase 9:436-40. 2003
    ..The use of TMS to probe the neurophysiology, and possibly alleviate, visual hallucinatory experiences is discussed...
  23. ncbi request reprint Attentional modulation of emotional stimulus processing: an fMRI study using emotional expectancy
    Felix Bermpohl
    Center for Non Invasive Brain Stimulation, Department of Neurology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, USA
    Hum Brain Mapp 27:662-77. 2006
    ..This enhancement effect is not present in neutral pictures and might parallel accentuated subjective feeling states...

Research Grants3

  1. Role of Visual Cortex in Tactile Object Processing
    Lotfi Merabet; Fiscal Year: 2005
    ..These results are likely to have implications for the rehabilitation and education of the blind and visually impaired. ..
  2. The Occipital Cortex in Cross-Modal Sensory Processing
    Lotfi Merabet; Fiscal Year: 2007
    ..These results are likely to have implications for both the rehabilitation and education of the blind and visually impaired. ..